WIXLIB

FURTHER,TOGETHERCOMPANY OVERVIEW

SOLVING THE WORLD’SHEALTHCARE CHALLENGESTAKES MORE THANONE ORGANIZATION.

WHAT IF?That’s the question we ask ourselves, over and over.It’s how we’ve made hearts beat even stronger andlonger, helped surgeons see inside patients, and givenkids with diabetes the ability to just be kids.It’s how we alleviated pain, restored health and extendedlife for more than 62 million people last year.But what if we could do more? What if we could partneracross the industry to help solve healthcare’s biggestchallenges?Like finding new ways to tackle the burden of chronicdisease. Lower the cost of healthcare. Get everyonethe care they need.No single entity in the healthcare system can solvethese challenges alone. That’s why we combined withCovidien in 2015 — expanding our scope so we can treatmore people, for more diseases, more efficiently thanever before.And it’s why we’re reaching even further. We’re puttingthe full power of our technologies, services, resources —and our people — to work with new partners, in new ways,to transform healthcare.Let’s take healthcare Further, Together.2015 MEDTRONIC COMPANY OVERVIEW1

OUR COMPANYAT A GLANCE** Based on FY2015 data, which includes Medtronic fiscal year as reportedand the one-quarter contribution of the Covidien transaction, which closedon January 26, 2015.OUR MISSIONALLEVIATE PAIN.RESTORE HEALTH.EXTEND LIFE.OUR BUSINESSESCARDIAC ANDVASCULAR GROUPAortic and PeripheralVascularCardiac Rhythm andHeart FailureCoronary andStructural HeartMINIMALLYINVASIVETHERAPIES GROUPEarly TechnologiesPatient Monitoringand RecoveryRenal Care SolutionsSurgical InnovationsRESTORATIVETHERAPIES urgical TechnologiesDIABETES GROUPDiabetes Serviceand SolutionsIntensive InsulinManagementNon-IntensiveDiabetes TherapiesGEOGRAPHIC NET SALES MIX*60%Americas10%Asia Pacific5% Greater China25%Europe,Middle East,Africa2

97.8MCHARITABLE CONTRIBUTIONS48%FoundationGiving155 20.3BCOUNTRIESIN REVENUE40%CashContributions153,000 62MILLION LIVESIMPROVEDPATENTS12%Product Donations2I ncludes support of medical conferences, charitable grants,and research and public education programs2Estimated fair market value17,500 80 SCIENTISTSANDENGINEERSMANUFACTURINGFACILITIES400 CLINICAL TRIALS 1.6BRESEARCHAND DEVELOPMENTINVESTMENT85,000 MDTEMPLOYEESNYSE SYMBOL2015 MEDTRONIC COMPANY OVERVIEW3

OUROFFERINGSToday, we’re known for our life-changinginnovations and breakthrough medicaltechnologies. We offer therapies that treatnearly 70 conditions, including some of theworld’s most challenging chronic diseases —like diabetes, obesity, cancer, and heartdisease. We also provide many essentialsupport products and services that are usedacross multiple procedures and along theentire continuum of care.Our legacy of innovation and unique positionas the world’s largest medical technologycompany allow us to play a central role intransforming healthcare. We’re collaboratingwith new partners in new ways to create newinnovations — ones that add both clinicaland economic value. So that tomorrow, evenmore people can get the affordable carethey need.OUR THERAPIESIMPROVE THE LIVESOF MORE THAN2 PEOPLEEVERY SECOND.4

SUPPORTPRODUCTSAND SERVICESCONDITIONSOUR THERAPIES TREATCardiac Rhythm symptomatic heart rhythmsA Atrial fibrillation Fast heart rates (tachycardia) Heart failure Slow heart rates (bradycardia)Coronary Coronary artery diseaseDiabetes ype 1T Type 2Ear, Nose, and Throat inus diseasesS Thyroid conditions requiringthyroidectomy Conductive or mixed hearingloss and single-sided deafness Otologic and neurotologicdisorders Sleep-disordered breathingEndovascular ortic aneurysmsA Deep vein thrombosis (DVT) Peripheral vascular disease Venous insufficiencyGastroenterological,Urogynecological, andUrological cid refluxA Appendicitis Barrett’s esophagus Chronic benign liver disease Chronic fecal incontinencePulmonary hronic nausea andCvomiting associated withgastroparesis* Colon tumors Crohn’s disease Digestive disorders Gallstones Gastrointestinal bleeding Gastrointestinal functionaldisorders Hemorrhoids Hernias Nutrition insufficiency Obesity Ovarian tumors and rupturedectopic pregnancies Overactive bladder andnon-obstructive urinaryretention Pancreatic cancer Polyps Uterine tumors and fibroidsNeurological cute ischemic strokeA Blood clots Brain aneurysms Brain tumors and lesions Chronic cancer pain Chronic leg and back pain Cranial trauma Dystonia* Essential tremor Hydrocephalus Obsessive-compulsivedisorder* Parkinson’s disease Severe spasticity Subdural hematomasMedical Supplies Acute respiratory distresssyndrome (ARDS) Asthma Chronic obstructive pulmonarydisease (COPD) Lung cancer Pulmonary embolisms Respiratory compromise Sleep apneaSpine and Orthopedic Cervical degenerativedisc disease Degenerative disc disease Lumbar spinal stenosis Orthopedic trauma Scoliosis Spinal fractures Tibial fractures ompression productsC Dialysis catheters Incontinence care Nutritional delivery Safety needles Wound careSurgical NavigationI mage-guidednavigation systems Navigation catheters Navigated instrumentationand workflows Surgical imaging andnavigationPatient Monitoring nesthesia monitoringA Cerebral/somatic oxygensaturation monitoring End tidal CO2 monitoring Long- and short-termcardiac monitoring Intraoperative nervemonitoring Pulse oximetryStructural Heart Congenital heart disease Heart valve diseaseRemote Monitoring* Humanitarian device in the UnitedStates — the effectiveness for this usehas not been demonstrated. ardiac and diabetesCdevice monitoring Health informatics andmonitoring systems Telehealth monitoringsystemsService Solutions ospital solutionsHand efficiency Care management services Education programsSurgical Products dvanced energyAelectrosurgicalinstruments Antibacterial deviceenvelopes Manual and poweredsurgical instruments2015 MEDTRONIC COMPANY OVERVIEW5

A HOSPITAL KNEW THATTO BETTER TREAT PATIENTSIT HAD TO FIRST TREAT ITSELF.Maastricht University Medical Center in theNetherlands was coping with the same challengeshealthcare providers around the world areconfronting. Patients have increasingly complexneeds that demand the latest innovative treatments.Talented healthcare workers are harder to attract andretain. And delivering the highest quality care at anaffordable cost is more necessary and difficult than ever.So a team of experts — medical center staff, the CEO,a professor, the director of the cardiovascular center,and Medtronic consultants — worked together toimprove the hospital’s operational processes, betteruse resources, and truly engage its employees.1Medtronic. A case study of Maastricht University Medical Center. 2015.6HOSPITAL SOLUTIONS AND EFFICIENCYWithin one year, the hospital’s Heart and VascularCenter treated 20 percent more patients withoutadding staff, cut the average patient length of stayby one-third, reached 100 percent compliance withguidelines — and saved 2.5 million in the process.1As a result, the hospital is well on its way to becominga Center of Excellence for the community.

MEANINGFUL INNOVATIONA STROKE OF UNKNOWN CAUSECREATES BIG CONCERN.A TINY DEVICE HELPS FIND THE ANSWERSTO HELP PREVENT ANOTHER ONE.On his way to a soccer game, 22-year-old ScottThompson suddenly began wobbling. His head startedthrobbing. What he thought was dehydration turned outto be much worse. The college student had suffered astroke. Surgeons removed a blood clot in his brain, but alooming question remained: What caused the stroke inthis seemingly healthy young man?short-term heart monitors may not detect it. SoScott’s doctors turned to a miniaturized, wirelesscardiac monitor — one-third the size of a AAA battery.They inserted it discreetly under the skin of Scott’schest during a simple outpatient procedure. Themonitor continuously recorded Scott’s heart activityand, within a few months, confirmed he had AF.Scott’s doctors suspected it was the result of an irregularheart rhythm called atrial fibrillation (AF) — believedto be responsible for many cryptogenic strokes (strokeswithout a known cause).1-3 Because AF often has nosymptoms and can occur infrequently, conventionalThe diagnosis not only gave Scott’s doctors theinformation they needed to prescribe strokepreventive blood thinners, it gave Scott the peaceof mind to live life fully again.For safety information, see back cover. eart Disease and Stroke Statistics 2015 Update Circulation. 2015; 131: e29-e322 Published online before print December 17, 2014, doi: 10.1161/CIR.0000000000000152.H Sacco RL, Ellenberg JH, Mohr JP, et al. Infarcts of undetermined cause: the NINCDS Stroke Data Bank. Ann Neurol. 1989;25:382-390.3 Petty GW, Brown RD, Jr., Whisnant JP, et al. Ischemic stroke subtypes: a population-based study of incidence and risk factors. Stroke. 1999;30:2513-2516.122015 MEDTRONIC COMPANY OVERVIEW7

NEARLY 400 MILLION PEOPLE NEED ABETTER WAY TO MANAGE DIABETES.A TEAM OF SPECIALISTS AND A COMPUTERARE CRUNCHING 125 MILLION CLUESTO UNCOVER NEW TREATMENTS.Today, there are nearly 400 million people withdiabetes in the world.1 And the number keeps growing— along with the cost and complexities of care. Insulinpumps and glucose monitors are great tools to helppeople manage blood sugar levels, but they’re notenough to deal with the epidemic.The hope is to uncover new ideas for treating andmanaging diabetes. New ideas to both improve careand reduce cost — so people living with diabetes canenjoy greater freedom and better health.So a team of specialists — from IBM’s Watson Healthcognitive computing business and Medtronic’s diabetesbusiness — are working to gather and analyze valuableinformation. Anonymous information like 125 milliondays of device use, electronic medical records, healthinsurance claims, and population health data.International Diabetes Federation. 2014 Diabetes Atlas. http://www.idf.org/diabetesatlas. Accessed Oct. 12, 2015.1 8PARTNERSHIPS

WHEN A COMMUNITYCAN’T ACCESS THE CARE IT NEEDS,AN UNCONVENTIONAL GROUP OF EXPERTSDIGS IN TO BREAK DOWN THE BARRIERS.Around the world, millions of people don’t getthe healthcare they need. Issues of access — cost,geography, awareness — result in disparities in care.It may be a remote Bolivian farmer who can’t get asimple surgery for a deadly, but treatable, condition.Or mothers in India at risk for gestational diabetes, butunaware of the threat.PARTNERSHIPSTogether, they come up with ways to addressbarriers to care. And each new cohort adds to ourunderstanding of how to better reach underservedpopulations around the world.Global Innovation Fellows, a program of MedtronicPhilanthropy, connects a team of local experts, includinghealth ministries and select nonprofit organizations, witha multidisciplinary cohort of Fellows — employees fromacross the company and around the world who want toengage in global health solutions through skilled service.The team spends three intense weeks on the ground,immersed in the community and its culture. They interviewlocal patients and healthcare workers. Observe localprocesses. Analyze the barriers. And brainstorm frugalinnovations — each adding their unique point of view.2015 MEDTRONIC COMPANY OVERVIEW9