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Wellness Offerings: NutritionFullyStockedKitchensOne aim of our SageFlex model is for Sage’s offices to be amagnet, not a mandate; we want employees to want to comeinto our offices. How do we achieve this? Well, one thing thathas been true for Sage since the beginning is that food hasalways been a magnet for us – it brings Sageans together andgathers us to connect and collaborate.In our offices, Sage uses a grocery delivery company calledPeapod to maintain fully stocked fridges that are full of fresh,brain health-promoting food, which employees can eat formeals and snacks throughout the day. This makes it so easy forSageans to eat nutritious food while they’re in the office andsaves them money too, reducing any grocery shopping thatwould be required for their meals during the work day. Sagewants to make sure that all of our employees have access tothe food they need, when they need it.Our kitchens have yogurt and other dairy products, meat, eggs,fresh fruit, salad ingredients, bread, healthy snacks, seltzers,teas, and even cold brew coffee and kombucha on tap.In-OfficeLunchDeliveryOn Mondays and Fridays,Sage also uses Rita’sCatering to deliver individuallypackaged lunches to ourCambridge office. Rita’s offersa changing menu each daywith multiple options that caterto different dietary needs.Employees who want a Rita’slunch place their order in themorning, and then pick it up inour office kitchens when it’stime to eat!How you can get these started: There are so many grocerydelivery and catering companyoptions based on location. Findsome in your area!Sage Therapeutics 202113

Wellness Offerings: RelaxationSometimes you need a little bliss during thework day.Did you know?A few times every year, Sage arranges forseveral masseuses from Boston ChairMassage, Inc. to come into our offices to give20-minute chair massage sessions thatemployees can sign up for. This is anotherincentive for employees to come onsite, asthese massage sessions are extremelypopular among Sageans – the appointmentslots fill up within minutes of opening.Sage also has several automated massagechairs in our Cambridge office that employeescan sign up to use for 30-minute blocks oftime, whenever they want.MassagesResearch findings suggest thatgetting a massage for relaxationpurposes reduces the physical andpsychological symptoms of stress.This is because getting a massagecan activate the parasympatheticnervous system, which is thebody’s natural mechanism formanaging stress (Medical NewsToday).Sage Therapeutics 202114

Wellness Offerings: Financial GuidanceRetirementPlanningServicesSage utilizes Principal to offer retirementplanning services to our employees. Theservices employees can receive include willand legal document preparation, a personalinformation organizer, and estate planningeducation tools. We want to help Sageanshave peace of mind when it comes to ing our Wellness Weeks, we alsooffer individual appointments with aRetirement and Budgeting Specialistfrom Marsh and McLennan. Thisallows Sageans to receive financialguidance in an in-person, morecustomized format.How you can get these started: Financial wellbeing is an area of wellness that often getsoverlooked, but in reality, it can be a huge source of stress.Giving employees access to financial resources is so important.We recommend making this a priority and finding providers thatwork best for you.Sage Therapeutics 202115

Wellness Offerings: Wellness WeeksWellnessWeeksWe want to support employees’ wellnessalways, but Sage selects several weeksthroughout the year to make it a main focus.During our Wellness Weeks, we offer a widevariety of sessions to excite and engage ouremployees in all different areas of wellness.The sessions include some hosted by theorganizations we partner with throughoutthe year, as well as some guest hosts: Flex & Stretch Class hosted by InnerCityWeightlifting (ICW) Retirement & Budgeting SpecialistSessions with Marsh and McLennan Career & Lifestyle Coaching Sessionswith Pathways to Parenthood “Brain Food” Session with NutritionistChloe Schweinshaut Group Cooking Class with Chef BenRobinsonHow you can get this started: What are your employees’ needs? What gets them excited? Think of healthand wellness resources that would benefit your specific organization andwould get employees to take a break from their day-to-day work and maketheir wellness a priority. Find providers that would be a cool addition to yourtypical offerings! Ensure that the sessions you host have plenty of capacity for interestedemployees to participate. We announce the events far in advance andcreate a page on our company intranet for employees to sign up for eachsession.See one of ourpast WellnessWeek scheduleson the nextpage!Sage Therapeutics 202116

Wellness Offerings: Wellness WeeksExample: Sage Wellness Week ScheduleSessionFormatICW Flex & Stretch Class45-minute group classRetirement & BudgetingSpecialist Sessions30-minute individual appointmentsNutritionist Consultations30-minute individual appointmentsCareer & Lifestyle CoachingSessions30-minute individual appointments“Nutrition During COVID: How toKeep Yourself Healthy” “BrainFood” Session45-minute company-wide Lunch &LearnErgonomic SpecialistConsultations30-minute individual appointmentsHouseplants 101 Webinar60-minute company-wide webinarCooking Class with Chef Ben60-minute interactive activityHealth Coach Consultations30-minute individual appointmentsEAP “The Science & Practice ofHappiness” Webinar60-minute company-wide webinarMake Your Own Bath Bomb Class60-minute interactive activitySage Therapeutics 202117

Wellness Offerings: What’s Next?We don’t want to stop here. In our commitment to supporting ouremployees’ wellness as their needs and the world around uscontinue to change, Sage is already thinking about what we cando next for our wellness initiatives. As we continue to bring ourSageFlex model to life, here are some new wellness offerings weare considering bringing to our employees Company-widestretch/screenbreaksTreadmill desksMeditation roomFinancial education“Brain Food” sessionsSpin bike desksSage Therapeutics 202118

Benefits ProgramsAt Sage, we celebrate the fact that everybody is different. It is fundamental to who we are as anorganization, as we are only able to think differently, push the boundaries of what’s possible, and forgenew pathways because of the uniqueness and individuality of every single Sagean who makes up ourteam.Because every person’s journey is different and therefore their needs are different too, we know that thebenefits that we offer to our employees can be anything but standard. Sage provides the basic benefitsthat are incredibly important for everyday life, such as medical, dental, vision, and life insurance andrelevant savings plans. However, our offerings don’t stop there. Sage’s overall benefits packageincludes a multitude of other options that go above and beyond and are custom-fit for our people.Sage Therapeutics 202119

Gifts forNew ParentsBenefits ProgramsCOVIDBenefitsHere is what we offer:Medical,Dental, Brain eParental andFamilyLeaveDiscretionaryVacationTimeTime onAssistanceProfessionalSupportCompanyWide MentalHealth DaysFive YearSabbaticalProgramConciergeServiceSage Therapeutics 202120

Benefits Programs: Clinical and Brain Health CareMedical,Dental, andVisionInsuranceVideoHealthcareVisitsCare is at the core of our benefits offerings; Sage believes that people can’t go italone and that everyone should have access to exceptional support, tools, andclinical care. All facets of wellbeing, including physical wellbeing, impact brainhealth, so we want to ensure that Sageans can receive any type of medical,dental, and vision treatment that they need.Sage uses BlueCross BlueShield of Massachusetts as our medical and dentalinsurance provider and VSP Choice Network as our vision insurance provider.Since we have employees all across the country and a significant part of ouremployee population is remote, it is of the utmost importance to us that ouremployees are able to see any type of clinician, no matter where they arelocated.The world has changed a lot in the past year.Healthcare providers’ virtual capabilities havegreatly expanded, so to adapt accordingly, ourbenefits package has evolved too to now includelive video healthcare visits through a primary careprovider called One Medical. This option makescare available to every single Sagean at anyplace, any time. Sage values flexibility, so we wantour benefits to give employees just that.Did you know?According to the National Alliance on MentalIllness (NAMI), 60 million Americans havemental health conditions. However, only roughlyhalf of those individuals receive mental healthtreatment. One of the main reasons for thisdisparity is that individuals who need care fortheir mental health often have difficulty findingproviders that are covered by their insurance.Since the treatment options for brain healthdisorders are multi-faceted, Sage has made it apriority to ensure that our medical insuranceprovider delivers optimal coverage forcounseling, therapy, and psychiatry cliniciansall around the U.S. We know that statistically,some of our employees will struggle with brainhealth at some point, so Sage wants to makesure that our employees are connected to thistype of care for any period in their life that theymay need it.Sage Therapeutics 202121

Benefits Programs: Professional SupportEmployeeAssistanceProgramThere may be times that employees find themselves in aspecific situation for which they need immediate one-onone support. This is why Sage provides an EmployeeAssistance Program (EAP) in partnership with KGA.Sageans can use our EAP to get expert advice in themoment, in the form of a live phone or video session formanaging emotional or mental distress or for anxiety,depression, substance misuse, or crisis intervention.ConciergeServiceTrying to get work done on your home? Planning a trip but don’t know whereto start? Need to organize a family event but can’t find the time to do it?We know that Sageans live full, busy lives and that a common source of stressfor everyone is having an ever-increasing to-do list with seemingly not enoughtime to do it all. Getting help with the little things can make a huge difference,so Sage partners with Circles Concierge, a personal assistance program thatour employees can use to get help with just about any tactical task at no costto them. This program can help with finding the best moving or storagecompany, coordinating pet services when going out of town, organizing aspecial flower delivery, booking spa or wellness appointments, and a lot more.Like the phrase “don’t sweat the small stuff”, by helping with tedious day-today errands Sage strives to reduce employees’ stress to allow them more timeto focus on what really matters.Our EAP also offers professional assistance foremployees and their families in the areas of budgetingand planning, debt management, parenting, childcarecoordination, and relationship counseling.Sage Therapeutics 202122

Benefits Programs: Professional SupportOur family members may require certain types ofeveryday care that are beyond what we can give withour own time and expertise constraints. Sage gives allof our employees a free Care.com membership sothat they can seek out care from a trusted, skilledprofessional for their children, senior family members,pets, and even their homes. This program providesSageans with services that range from child or seniorcaregiving to tutoring to housekeeping. Additionally,with this benefit, Sageans can use up to 10 days ofsubsidized emergency backup care throughCare.com. As a whole, this benefit supports Sageansso they can focus on areas of life that they want togive their full attention to, including work, withoutoverextending themselves.How you can get these started: As a company that strives to supportwellness and self-care for ourselves andothers, Sage knows that our missionmeans nothing if those who need care,treatment, and support aren’t able toreceive it. Regardless of which exactproviders you choose for your organization,ensuring that all of your employees haveaccess to exceptional care is an imperativestart to them being able to do their bestwork, carrying your company’s missionforward, and making a difference in theworld.CaregiverServiceSage Therapeutics 202123

Benefits Programs: Time OffDiscretionaryVacationTimeSage gives employees discretionaryvacation time. That’s right – Sageans cantake as much time off as they need,whenever they need, to rest, recharge, andspend time with their families. We believethat Sageans’ lives outside of work are justas important as the time they spend working,and we empower Sageans to create thebalance they need in their lives so that theycan be the best version of themselves anddo their best work.Five YearSabbaticalProgramFor employees who have devoted a great deal of time to Sage,we want to give a significant amount of time back, for them topause on their Sage journey and devote it to other areas of life– their wellbeing, their family, or others. All employees whohave worked at Sage for five continuous years are eligible totake a five week fully paid sabbatical to do anything they want –whether it be traveling, self-development in the form of trainingor community service, or just taking a substantial break. Givingthe opportunity for employees to take this much time off allowsthe time to be meaningful, and we know that fulfilled employeesare healthy and engaged employees.Sage Therapeutics 202124

Benefits Programs: Time OffDid you know?In a survey conducted by the AmericanPsychological Association (APA), Americansin the workforce who took vacation timereported having improved mood, increasedenergy and motivation, higher productivityand work quality, and less stress when theyreturned to work. This highlights the mutualbenefit of taking time off for bothemployees’ wellbeing and organizationalsuccess.CompanyWide MentalHealth DaysResearch shows that the days immediately followingDaylight Savings are some of the days when individualsare most at risk for experiencing mental health strugglesor crises. Sage gives two Mental Health Days during theyear on the two Mondays after Daylight Savings, whichthe whole company has off to rest and do what theyneed to support their own health.How you can get these started: Sage recommends establishingtime off policies that enable youremployees to take the amount oftime off that they really need. While many companies do this, acommon problem currently facingmany companies is gettingemployees to actually use andmaximize the paid time off thatthey’re given. A theme across mostresearch is that many employeesfeel that their workload is toooverwhelming or their companiesaren’t actually supportive of themtaking time off. It’s essential foremployees to use their time off forit to be beneficial, so create aculture that advocates for allemployees – at every level – to doso.Sage Therapeutics 202125

Benefits Programs: Parental BenefitsExtensiveParental andFamilyLeaveSage values the moments that trulymatter along every employee’s journey,especially important life and familyevents. Sageans who are welcoming anew child into their family can take 12weeks of 100% paid parental leave orthree days of 100% paid grandparentleave. Birth-giving parents can also takeone week of pre-partum leave and eightor more weeks of disability leave. Inaddition, Sageans can take four weeksof 100% paid and eight additional weeksof 50% paid family leave to care for theserious health condition of a familymember or other significant person in anemployee’s life.Family-centricity is in all that we do, andSage wants our employees to be able tobe fully present and free of added stressfor these moments with their loved ones.AdoptionAssistanceSage knows that cost can be asignificant hurdle for those who decideto grow their families throughadoption. For this reason, Sage offersto reimburse up to 10,000 for anyexpenses related to the adoption of achild.Gifts forNew ParentsWe want to both support andcelebrate with employees who aregrowing their families, so we give anassortment of gifts to supportSageans who are new parents. Ourgifts for new parents include a 6month supply of diapers and wipes, upto 350 of breast pump assistance, aTaskRabbit gift card for help withhousehold chores such as groceryshopping, a Milk Stork partnership sonew mothers who are traveling forbusiness can ship breastmilk whileaway from home, and access to thefull suite of Ovia health applications.Sage Therapeutics 202126

Benefits Programs: COVID BenefitsWe recognize that our employees work very hard and achieve incredibleresults. This often entails work days that are long and involve manymeetings. To acknowledge this Sage has Friday Sizzlers, which means thatevery Friday, all employees’ calendars are blocked off beginning at noonuntil the end of the day. During Friday Sizzlers, employees cannot scheduleany meetings and are not expected to respond to any messages or emails.The time is meant for employees to use however they need, whether it behaving some uninterrupted time to catch up on work or starting theweekend early.While Sage originally only had Friday Sizzlers during the summer

Taking Action 3 We are living amidst a pressing brain health crisis. It is estimated that more than 19 million adults in the U.S. and more than 260 million people worldwide suffer from depression, demonstrating an existing worldwide brain health pandemic that was previously hidden, which has been exacerbated and brought to light by the