Pharmaceutical Packaging And Medical Devices

Transcription

Pharmaceuticalpackaging andmedical devicesPolypropylene, polyethylene,and EVA copolymers

Differentiated solutions for thehealthcare industryCommitmentDedicated storage facilities andquality management protocols toensure the highest quality standards.GuaranteeRepsol offerHigh quality productsReady to be part of new projectsCapable of developing tailor-made gradesExcellent logistics serviceTechnical service and developmentOur driveTo fulfill our customers’ needs:Product reliability and traceabilityComplianceLong term commitmentCertifying our products to meetEuropean & US Pharmacopoeias(USP/EP).ServiceAligning our Quality System with theGood Manufacturing Practicesrequired by the industry.

Repsol. A globalmulti-energycompanyWith over 8 decades of experienceIt is leading the energy transition with itsambition of achieving zero net emissions by2050.Present throughout the energy value chain,the company employs 24,000 peopleworldwide and distributes its products innearly 100 countries. Its customer-focusedproduct and services portfolio meets allconsumer needs of around 24 millioncustomers, whether at home or on the move.Repsol Campus, Corporate Headquarters in MadridLEED Platinum certificate, awarded by theprestigious U.S. Green Building Council (USGBC), fornew buildings construction REPSOL QUIMICA, S.A. 2022. All rights reserved.

ChemicalsRepsol manufactures a wide variety of products,ranging from base petrochemicals to derivatives.Base petrochemicals: ethylene, propylene, butadiene,and benzene.Intermediate products: styrene, propylene oxide, polyetherpolyols, and propylene glycols.Polyolefins: polypropylene (PP) and PP compounds, both highand low-density polyethylene (HDPE and LDPE), metallocenelinear low density polyethylene (mLLDPE), ethylene vinyl acetate(EVA), and ethylene butyl acrylate (EBA) copolymers.Over 100 scientists and researchers working for youIncluding qualified personnel specialized on ProductStewardship.Repsol’s commitment to R&D is evidence of the company'saim to attain business excellence to meet future horizons.Added valueRepsol’s Chemicals Division, with a high degree of integration,focuses its strategy on the constant generation of valuethrough differentiated products and services. REPSOL QUIMICA, S.A. 2022. All rights reserved.

ChemicalsOur goalTo manufacture and sell polyolefins or pharmaceuticalpackaging and medical devices, offering the maximum quality,service, commitment, and compliance worldwide, keeping thepatients’ safety as our number one priority.Over 40 years of experience producingand selling polyolefinsGrowing from our strengthsOver 40 years of experience producing and selling polyolefinswith a well-built prestige in Europe.Three integrated production facilities in the Iberian Peninsula.We have experience launching products with the maximumcleanliness and stringent manipulation procedures.Food packaging: we supply regularly to the food packagingindustry.Qualified in pharmaceutical applications. Repsol’s propyleneglycol USP/EP is qualified and approved for use as an excipientin pharmaceutical applications. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Over 30 grades for healthcarePolyolefins for pharmaceutical packaging and medical devicesRepsol takes another step in differentiating its solutions and offers.A suitable range of polyolefins: high and low density polyethylene (HDPE, LDPE), ethylene vinyl acetate copolymers (EVA)and polypropylene (PP).An outstanding and differentiated level of service.Eager to continue developing differentiated products.We put your needs first, always. Our tailor-made solutions are proof of our commitment to your singular cause.Our industry is full of challenges awaiting inspired solutions. That’s where we come in.Polypropylene homopolymerLow density polyethyleneHeterophasic polypropylene copolymerHigh density polyethylenePolypropylene random copolymerEVA copolymer REPSOL QUIMICA, S.A. 2022. All rights reserved.

Working for a more sustainable futureAt Repsol, we believe in the circular economy, and we run specific projects that minimize the environmentalimpact of our materials. To this end, we are committed to making our industrial processes increasinglyefficient and reducing the carbon footprint of our polymers.We have a specialized circular economy departmentdedicated to recycling post-consumer materials to drivedevelopment of new materials offering solutions based oninnovative polyolefins with recycled content.We use recycled plastics in critical applications, creatingnew markets for plastic waste and driving circularity bygiving that waste a new use. As a result, we offer a widerange of polyolefins with recycled content that deliverexcellent engineering performance.We have circular polyolefins obtained by incorporatingpyrolysis oil, from chemically recycled plastic waste notsuitable for mechanical recycling, together with virginfeedstock into our petrochemical process, reducing theconsumption of non-renewable resources.These circular polyolefins have the same properties andquality as virgin material and are therefore apt for healthcarepackaging and medical devices.We have obtained ISCC PLUS certification for circular andtraceable polyolefins that use plastic waste as raw material.Moreover, our wide range of polyolefins is 100% recyclable.Our ambition is to recycle the equivalent of 20% of thepolyolefins we produce to support, in conjunction with theother initiatives in Repsol’s circular economy strategy, thegoal we announced in December 2019: to reach net zeroemissions by 2050.To contribute to the company’s emissions neutrality goal, ourchemicals business has launched its 3030 Plan, intended tocut our carbon intensity by 30% by 2030.Advancing the circular economy and lowering carbonintensity in our chemicals business will contribute towardstransforming Repsol’s industrial operations, as well asdeveloping high-value-added raw materials, making itpossible to manufacture an infinite number of productsthat improve human well-being, safety, and quality of lifewhile enhancing the environment. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Voluntary commitments.Working to build a moresustainable worldBecause we care. At Repsol we believe that our society needsa transition towards a new Circular Economy, and we are fullycommitted to developing solutions, minimizing the impact ofour polymers on the environment.We have strengthened our commitment to sustainability by submittingour voluntary pledge in response to the European Commission’s call forstakeholders to come forward with pledges to boost the uptake ofrecycled plastics. The European Commission target is for 10 million tons ofrecycled plastics to find their way into products in the EU by 2025.To meet this ambitious EU target, Repsol has the ambition of recyclingthe equivalent of 20% of our polyolefin production by 2030. Thanks toRepsol’s commitment, in less than 10 years, 360 kty of plastic wastewill be diverted from landfill and will become raw materials to producenew chemical products. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Polypropylene homopolymerPropertiesGradeAdditivesMFICharpy impact Melting pointISO 1133 g/10 min strength notchedºC230ºC 2.16 kgISO 179 kJ/m2FlexuralmodulusISO 178 MpaComplianceEurPhUSPHPP08G841641500-3.1.3 / 3.1.6661.1HPP09M931641500Slip agent /Antiblock3.1.3 / 3.1.6*661.1*HPP12G1241641550-3.1.3 / 3.1.6661.1HPP25G2531641600-3.1.3 / 3.1.6661.1HPP25G12541571250-3.1.3 / 3.1.6661.1HPP40N402.51641700Nucleating agent3.1.3 / 00Clarifying agent/Radiation ResistantClarifying agent/Antistatic**ApplicationsBiocompatibilityUSP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11Pharmaceutical packaging, closures, pouches and medicalfilms.Pharmaceutical packaging, caps and closures.Injection molding, caps and closures and pharmaceuticalpackaging.Syringe parts, caps and closures, pharmaceuticalpackaging, injection molding items.Improved impact resistance. Syringe parts, pharmaceuticalpackaging, caps and closures, injection molding itemsThin wall injection molding, labware, dispensers.Gamma ray and E-beam resistant high fluidity PP resin.Offers stiffness and excellent transparency.Injection molding medical applications and labware.Offers stiffness and high transparency.* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comHeterophasic polypropylene copolymerAll ourpolypropylenegrades arephthalate freeThe information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Heterophasic polypropylene copolymerPropertiesGradeMFIISO 1133 g/10 min230ºC 2.16 kgHPB15NMDAdditivesCharpy impact Melting pointºCstrength notchedISO 179 kJ/m2156FlexuralmodulusISO 178 Mpa1600164ApplicationsComplianceNucleating agentEurPhUSP-In compositionBiocompatibilityUSP 87 USP Cytotoxicity (Elution Test) Injection molding medical applications. OffersUSP 88 class VI ISO 10993-4, -5, -10, -11 excellent impact/stiffness balance* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comPolypropylene homopolymerPolypropylene random copolymerPolypropylene homopolymer & Heterophasic polypropylene copolymerHPP55RMD HPP55CMD1800HPP40N1700Flexural Modulus1600Polypropylene homopolymerHPP25GHPB15NMDHeterophasic Polypropylene 0103020MFI405060'The information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Polypropylene random copolymerGradePropertiesAdditivesMFICharpy impactMelting pointFlexuralISO 1133 g/10 min strength notchedºCmodulus230ºC 2.16 kgISO 179 kJ/m2ISO 178 MpaComplianceEurPhUSPHPR02CMD1.6 9143800Clarifying agent**HPR02W1.8 9143800Clarifying- agent3.1.3 / 3.1.6661.1HPR09G98145950-3.1.3 / 3.1.6661.1HPR09M981459503.1.3 / 3.1 R50CMD5051491150**HPR75CMD7561491050Slip agent/AntiblockClarifying agent/AntistaticClarifing agent/Radiation resistanceClarifying agent/AntistaticClarifying agent/Antistatic**ApplicationsBiocompatibilityUSP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11Medical packaging, film and pouches, vials.Large volume parenteral BFS bottles apt for autoclavesterilization at 121ºC. Medical packaging, film and pouches.Barefoot grade. Medical packaging, films and pouches.Injection molding items.Contains slip and antiblock. Medical packaging, labware,caps and closures and ISBM.Caps and closures, syringe parts, medical devicecomponents.USP 87 USP Cytotoxicity (Elution Test) Caps and closures, syringe parts, tubes, labware. GammaUSP 88 class VI ISO 10993-4, -5, -10, -11 and E-beam rad.USP 87 USP Cytotoxicity (Elution Test) Caps and closures, syringe parts, medical deviceUSP 88 class VI ISO 10993-4, -5, -10, -11 components.USP 87 USP Cytotoxicity (Elution Test)Small syringes, thin wall parts.USP 88 class VI ISO 10993-4, -5, -10, -11* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comHeterophasic polypropylene copolymerLow density polyethyleneStringent productionprocedures to ensureproduct consistencyand the highestquality standardsThe information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Polypropylene Random lexural 10203040MFI50'607080ISO 1133Low density polyethylene

Low density harpy impact Melting pointISO 1133 g/10 min strength notchedºC230ºC 2.16 kgISO 179 kJ/m2ApplicationsEurPhUSPHLD01S0.3922110No additives3.1.3. / 3.1.4661.1HLD01S10.55928117No additives3.1.3. / 3.1.4661.1HLD02S2920110No additives3.1.3. / 3.1.4661.1HLD02G2920110Antioxidants/Antiblock/Slip agent3.1.3. / 3.1.5661.1HLD08S8920109No additives3.1.3. / 3.1.4661.1HLD20S22923104No additives3.1.3. / 3.1.4661.1BiocompatibilityUSP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11Excelllent flexibility for small volume parenteral bottlesand ampoules.Small volume parenteral bottles and ampoules for steamautoclave treatment.Very flexible grade for ampoules. LDPE for pharmaceuticalbags, pouches and medical devices.Soft LDPE containing slip and antiblock. For pharmaceuticalpackaging, caps and closures and other medical devices.Extrusion coating and medical films. components.Caps and lids. Injection molded parts that require flexibility.* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comPolypropylene random copolymer930HLD01S1HLD01S920DensityHigh density 10'121416182022A comprenhensive range ofproducts designed according tothe standards of pharmaceuticalpackaging and medical devicesThe information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

High density polyethyleneGradePropertiesAdditivesMFIMFIISO 1133 g/10' ISO 1133 g/10'190ºC 21.6 kg190ºC 5 kgMFIISO 1133 g/10 min230ºC 2.16 kgDensityISO 1183kg/m3Melting 0135 Antioxidants 3.1.3 / 3.1.5HHD55G0.25-23955135 Antioxidants 3.1.3 / 3.1.5HHD62G0.3-30959133 Antioxidants 3.1.3 / 3.1.5HHD55G1-245.5955136 Antioxidants 3.1.3 / 3.1.5USP661.1BiocompatibilityTypical extrusion blow molding grade for pill jars, offeringUSP 87 USP Cytotoxicity (Elution Test)increased density and barrier properties. Typically alsoUSP 88 class VI ISO 10993-4, -5, -10, -11converted in IBM process.USP 87 USP Cytotoxicity (Elution Test) Blow molding HDPE grade presenting stiffness and excellentstress cracking resistance. Grade used for pill jars andUSP 88 class VI ISO 10993-4, -5, -10, -11 containers for pharmaceutical packaging.USP 87 USP Cytotoxicity (Elution Test)Packaging, diagnostic and tubes, blow molding bottles.661.1USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test) Extrusion blow molding HDPE grade for pharmaceutical661.1USP 88 class VI ISO 10993-4, -5, -10, -11 packaging including BFS processes. Good process stability.661.1* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comLow density polyethyleneEVA 0GA helping hand ontechnical mattersto obtain the 533.544.555.5620MFI25'MFI 2.16 kg30MFI 21.6 kgThe information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

EVA tionsBiocompatibilityMFIISO 1133 g/10 min230ºC 2.16 kgVA sHVA28G2728AntioxidantsUSP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11USP 87 USP Cytotoxicity (Elution Test)USP 88 class VI ISO 10993-4, -5, -10, -11It is used for transdermal patches but can also be used for small blow molding, injectionmolding or tubing.Extrusion of medical film and production of medical bags, seals.Medical film and bags, tubing, seals and closures.Medical film.Injection molding medical devices.* Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service & DevelopmentDepartment atd poliolefinas@repsol.comHigh density polyethyleneQualified in morepharmaceutical applicationsRepsol's propylene glycolUSP/EP is qualified andapproved for use as anexcipient in pharmaceuticalapplicationsThe information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

SterilizationRepsol HealthcareAutoclaveEtOGradoGamma and E-beam radiationPolypropylene Homopolymer HPPOnly for HPP55RMDPolypropylene Random Copolymer HPROnly for HPR35RMDLow Density Polyethylene HLD*High Density Polyethylene HHDEVA Copolymer HVARepsol Healthcaregrades resiststerilization withoutaffecting the aestheticor mechanical propertiesof the polymer.* For specific information on sterilization resistance, please contact the Tecnnical Service and Development DepartmentMEDICAL POLICY DISCLAIMERSThe use of this product in any Medical Device must comply with the following criteria:Class I Medical Devices (European Union and/or U.S. FDA): the product may only be used for this purpose with prior notification to REPSOL QUIMICA, S.A. of each specific final application.Class II Medical Devices (European Union and/or U.S. FDA): the product may only be used for this purpose with REPSOL QUIMICA, S.A.’s prior written approval.This product may not be used for implantable devices and for Class III Medical Devices (European Union and/or U.S. FDA).REPSOL QUÍMICA, S.A. makes no warranties, express or implied, which extend beyond the description contained herein. Nothing herein shall constitute any warranty of merchantability or fitness for a particular purpose.Before using a product sold by REPSOL QUÍMICA, S.A. users should make their own independent determination that the product is safe, lawful and technically suitable for the intended use.REPSOL QUÍMICA, S.A. accepts no liability from the use of its materials in conjunction with other materials.The information contained herein is based on REPSOL QUIMICA’s current knowledge and experience and is presented in good faith for guidance only. Although REPSOL QUIMICA declares to have been most diligent when including the information contained herein, taking into account that several and different factors may affect the processing, application or useof the products, the convertor shall be responsible in every case for the conditions under which the products are transformed as well as for the final use given to them. REPSOL QUIMICA warns that this information may undergo variations or improvements; therefore REPSOL QUIMICA is not obliged to reflect these in this document or to communicate them towhomever may have access to it. Moreover, these readers should be aware that some or all of the products might be protected by intellectual property rights. REPSOL QUIMICA, S.A. 2022. All rights reserved.

Safety and quality are our priorityAll our petrochemical complexes and production plants meet the most stringent quality and safety standards.Our petrochemical complexes, packaging production plants and logistics centers have rigorous food-safety managementsystems in place and hold ISO 45001.Their manufacturing, distribution, transport, and end-product storage processes are also certified to the ISO 9001 quality standard.The Chemicals units at our complexes operate under an Energy Management System. Our Certified Environmental ManagementSystem guarantees that Best Available Practices and Technologies are in place to minimize the impact of our sites.IATF 16949 certifiedIn 2021 we have obtained the highest certification for our auto products, having adapted all our automotive materials productioncenters under the IATF 16949 standard, an international standard for quality management systems in the automotive industry.This standard is the most demanding for quality management systems in the automotive sector at an international level and oneof the essential requirements that car manufacturers require from their suppliers.CertificationsAll Repsolcomplexesand plantsISO 45001FSSC 22000All RepsolcomplexesISO 9001ISCC PlusPuertollano,Tarragonaand SinesPuertollano,Tarragonaand Monzón plantsISO 50001ISO 14001ISO 14064IATF 16949CollaborationMay 2022IntrapreneurshipResults orientationPuertollanoand Monzón plantsUNE–EN 15343Inspiring leadershipAccountability REPSOL QUIMICA, S.A. 2022. All rights reserved.

Chemicals Customer CareSpainItalyTel.: 900 10 32 39Tel.: 800 60 509 999Tel.: 34 91 753 18 01Tel.: 34 91 753 18 04PortugalGermanyTel.: 800 60 501 111Tel.: 800 60 504 444Tel.: 34 91 753 18 05Tel.: 34 91 753 18 00FranceUnited KingdomTel.: 800 60 503 333Tel.: 800 60 502 222Tel.: 34 91 753 18 02Tel.: 34 91 753 18 03sacrq@repsol.comwww.repsol.com

Corporate HeadquartersMéndez Álvaro, 4428045 Madrid. SpainTel.: 34 91 753 81 00www.repsol.comTechnical Service & DevelopmentRepsol Technology LabAgustín Betancurt, s/n28935 Móstoles, Madrid. SpainTel.: 34 91 753 86 00atd poliolefinas@repsol.com

USP 88 class VI ISO 10993-4, -5, -10, -11 1900 * Clarifying agent/ Antistatic HPP55CMD 164 All our polypropylene grades are phthalate free *Repsol Healthcare grades are DMF listed. For more detailed information on DMF listing, European Pharmacopoeia (Ph Eur.) and United States Pharmacopoeia (USP), please contact Repsol's Technical Service .