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C H I L E A N SO C I E T Y F O R C E L L B I O L O G YX X VI ANNU A L M E E TINGO ctober, 23 – 27th , 2012Puerto V arasSPO NSORSA N I L L O A T C-71 E I NST I T U T O M I L E N I O , C E N T R O I N T E R D ISC IP L I N A R I O D E N E U R O C I E N C I ASD E V A L PA R A ISOC E N T R O D E I N V ES T I G A C I O N ES B I O M E D I C AS, U N A BC ENTRO F ONDAP DE RE GUL A C ION DE L G ENO M AF O N D E C Y T 1095089 Y 1100137, U. D E C H I L EF O N D E C Y T D E C O O P E R A C I O N I N T E R N A C I O N A L 1120512 Y 1110310,P. U N I V E RSI D A D C A T O L I C A D E C H I L EC E N T E R F O R M O L E C U L A R ST U D I ES O F T H E C E L L (C E M C)D E PA R T M E N T O F B ASI C SC I E N C ES, F A C U L T Y O F D E N T IST R Y, U. D E C H I L EFUNDA C ION C HIL ENA PARA BIO L O G IA C E LUL ARM I L L E N N I U M I NST I T U T E O N I M M U N O L O G Y A N D I M M U N O T H E R A PYT H E B I O M E D I C A L N E U R OSC I E N C E I NST I T U T E, A M I L L E N N I U M SC I E N C E I N I T I A T I V E (MSI)I NST I T U T ET H E F O G A R T Y I N T E R N A T I O N A L R ES E A R C H C O L L A B O R A T I O N A W A R D (F I R C A)-N I HE X H IB IT ORSA . B R I L Y C I A L T D A – A L A T H E I A M E D I C A SA - A N D ES I M PO R T L T D AA R Q U I M E D SA – B I O C A N T – B I OSO N D A SA – ST E M C E L – B D B I OSC I E N C ESB I OSC H I L E I G SA – C I E N T E C SA – G A L E N I C A SA – G E N ESYS C H I L E L T D AG E N E X PR ESS – L A B T E C – L O N C O T E C SA – T C L L T D AT E C N I G E N SA – SI A L C H I L E – SU D E L A B SA
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 2012C H I L E A N SO C I E T Y F O R C E L L B I O L O G YX X VI ANNU A L M E E TINGO C T O B E R, 23-27, 2012PU E R T O V A R ASPRO GRA M1
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20122T U ESD A Y, O C T O B E R 23, 201209:00 – 13:00RegistrationConvention C enter Foyer11:30 – 12:30Technical Lectures - C albuco RoomM B F Bioscience Inc. and A rquimedC uantificación C elula r por Estereología y Reconstrucción Neu ronal en 3DJose M aldonado, PhD, M B F L atino A mérica, B rasilTechnical Lectures - T ronador RoomTecnigenA ctin C ytoskeleton and Plant StomataJuan A . Negrón-Ber ríos, Interamerican University of Puerto Rico12:30 – 13:30Technical Lectures - C albuco RoomBioTek Inst ruments and BiosC hile I GSAC ell-based Assays in D rug Discovery for Lead G eneration and Probing D rug E ffectsPeter Banks, PhD, Scientific Director, BioTek Instruments, Inc.Technical Lectures - T ronador RoomAgilent and G enexpressF rom H uman to Plants: A pplications of targeted sequence capture and next-generation sequencingtechnologies in studies of human genetic disorders, cancer and model organisms.Y uri Morei ra, L atin A merica F ield A pplication Scientist, Agilent.13:30 – 15:30L unch16:00 – 17:00InaugurationVolcanes RoomC hair: M aría Rosa BonoPlena ry Lectu re L uis Izquierdo F ernandezC hair: Juan L ar raínS k e l e t a l M u sc l e a n d D i se a se : A j o u r n e y f r o m t h e b e n c h s i d e t o t h e b e d s i d e . E n r i q u e B r a n d a n .Department of Cell and Mo lecular Bio logy, CARE, MIFAB, Catholic Universit y o f Chile. Santiago,Chile.17:00 – 18:00Coffee B rea k – E xhibitorsConvention C enter Foyer18:00 – 19:30Minisymposium I “T raffic, Signals, Receptors and Synapses”C albuco RoomC hair: M aria Rosa Bono and Co-Chair: F rancisca B ronfmanB D N F induces a ret rograde apoptotic signaling endosome containing p75 neurotrophin receptor(p75) in sympathetic neurons (SC Gs). Escudero C A, Galleguillos C, Flores CM, Bronfman FC.Millennium Nucleus in Regenerative Biology (MINREB), Facultad de Ciencias Biológicas, PontificiaUniversidad Católica de Chile, Santiago, Chile. caescude@gmail.comSorting nexin 17-binding cluster within the cytoplasmic tail of L RP1 mediates receptor recyclingthrough the basolateral sorting endosome. Pamela Farfán1,2, Jiyeon Lee3, Jorge Larios1,2, Pablo Sotelo1 ,Guojun Bu3 and M aría-Paz M arzolo1,2 . 1Laboratorio de Tráfico Intracelular y Señalización,Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, 2MINREB; P.Universidad Católica de Chile 3Dept. Neurosci, Mayo Clinic, Jacksonville, Florida 32224, USA.
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20123F rizzled receptors in p rogenitor and immatu re neurons of the adult hippocampus. Lorena V arelaNalla r 1,2, Carla Calderon Toledo1 and Nibaldo C. Inestrosa1. 1Centro de Envejecimiento y Regeneración(CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, P. UniversidadCatólica de Chile, 2Centro de Investigaciones Biomedicas, Facultad de Ciencias Biologicas y Facultad deMedicina, Universidad Andres Bello, Santiago, Chile. lpvarela@uc.clDiapause formation and downregulation of Insulin-li ke signaling via D A F-16/F O X O delays axonaldegeneration and neuronal loss. A nd rea C alixto1, Juan S. Jara1 and Felipe A. Court1,2. 1CatholicUniversity of Chile and 2Neurounion Biomedical Foundation. acalixto@bio.puc.clPolycomb-G roup proteins (Pc G) E zh1 and E zh2 differentially regulate PSD-95 gene exp ression indeveloping hippocampal neu rons. Berta H enríquez1, Fernando J Bustos1,2,3, Francisca Blanco1,2, AlvaroBecerra1, Claudio Salas1, Felipe Simón1, Martín Montecino1,2, Brigitte van Zundert1.1Biological SciencesFaculty, Andres Bello University. 2FONDAP Center for Genome Regulation. 3University of Concepcion.berta.henriquez.cabezas@gmail.comW nt signaling at the vertebrate neu romuscula r junction analyzed through in vivo elect roporation.Juan Pablo H enríquez*, Sylvain Marcellini, Daniel Sandoval, Jaime Teneb, Javier Espinoza. Departmentof Cell Biology and CMA Bio-Bio, Universidad de Concepcion, Concepcion, Chile. *jhenriquez@udec.clMinisymposium II “C ell Biology of Disease”T ronador RoomC hair: M auricio González and Co-C hair: Silvana ZanlungoNovel mechanisms cont ributing to hepatic steatosis and insulin resistance in the A G PA T2 deficientmouse model of congenital generalized lipodystrophy. V íctor Cortés 1,2,, Anil Agarwal3, AbhimanyuGarg3 and Jay D. Horton2,3. 1Department of Nutrition, Diabetes and Metabolism, School of Medicine,Pontificia Universidad Católica de Chile. 2Departments of Molecular Genetics and 3Internal Medicine,University of Texas Southwestern Medical Center, Dallas, TX, USA. vcortes@med.puc.clM aternal supraphysiological hypercholesterolemia in p regnancy leads to placental endothelialdysfunction. Leiva A, Diez de Medina C, Guzmán-Gutiérrez E, Abarzúa E, Pardo F, Sobrevia L. Cellularand Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynecology, Faculty ofMedicine, Pontificia Universidad Católica de Chile. aaleiva@puc.clM itochondrial fusion dynamics in skeletal muscle of healthy and alcoholic rat. V eronica E isner 1,Guy Lenaers2, Gyorgy Hajnoczky1. (1)Thomas Jefferson University, Philadelphia, PA. (2) INSERM U583, Institut des Neurosciences de Montpellier, France. veronica.eisner@jefferson.eduH emeoxygenase 1 as a therapeutic target for Systemic L upus E rithematosus. Juan P. M ackern 1,Carolina Llanos2, Leandro J. Carreño1, Camila B. Schmidt1, Ignacio Anegon3, Sergio H. Jacobelli2 andAlexis M. Kalergis1,2. 1Millennium Institute on Immunology and Immunotherapy. Departamento deGenética Molecular y Microbiología. Facultad de Ciencias Biológicas. Pontificia Universidad Católica deChile. 2Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, PontificiaUniversidad Católica. 3INSERM U1064, Nantes, France. jmackern@bio.puc.clC1 interaction with Trypanosoma cruzi calreticulin mediates ex vivo infection of human placenta.Castillo C, Duaso J, Maldonado I, Ramírez G, Valck C, Kemmerling U* and F er rei ra A*. ICBM, Facultyof Medicine, University of Chile. aferreir@med.uchile.clM utations in protein disulfide isomerases a re lin ked to the development of A LS. Woehlbier U.,Gonzalez-Perez P., Colombo A., Andreu C., Torres M., Valenzuela V., Diaz A., Armisen A., Sagredo A.,Palma K., Concha M., Brown R. and Hetz C. Biomedical Neuroscience Institute, and Center for MolecularStudies of the Cell, ICBM, Faculty of Medicine, University of Chile, Santiago Chile and University ofMassachusetts, USA.20:30Dinner
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 201222:00 – 23:004Plena ry Lectu re T he Biomedical Neu roscience Institute, a M illennium Science Initiative (MSI)Institute.Volcanes RoomC hair: A ndrés CouveSmell and the single neu ron: T h ree-dimensional reconst ructions of olfactory neu rons offer insightsinto neuronal morphologic diversity and odor coding. K ristin Baldwin. Department of Cell Biology,Scripps Res Inst, La Jolla, CA, USA.
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20125W E D N ESD A Y , O C T O B E R 24, 201208:00Poster Mounting Session I: N 1 to N 80Convention C enter Foyer09:00 – 11:00Symposium M illennium Institute on Immunology and ImmunotherapyC albuco RoomC hair: A lexis K alergis“T ranslational Immunology”E ffects of a t ransforming human ret rovi rus (H T L V) on the cellula r response to D N A damage.Susan J. M ar riott, Department of Molecular Virology and Microbiology, Baylor College of Medicine,One Baylor Plaza, Houston, Texas.T he ala rmin Interleukin-33 receptor and its role in inflammatory responses. M arcela H ermoso,Facultad de Medicina, Universidad de Chile.Molecula r modulation of the immunological synapse to imp rove the human immune response.A lexis M . K alergis, Facultad de Ciencias Biológicas y de Medicina, P. Universidad Católica de Chile.T he hea rtb rea k of studying glucocorticoid receptors at the N I H . John A . C idlowski, MolecularEndocrinology Group, Laboratory of Signal Transduction, NIEHS, NIH, DHHS, Research Triangle Park,North Carolina, USASymposium T he Biomedical Neu roscience Institute, a M illennium Science Initiative (MSI) Instituteand T he Fogarty International Resea rch Collaboration A ward (F I R C A)-N I HT ronador RoomC hair: L isette Leyton“C ell-C ell Interactions Governing C ell M igration”Regulation of Rho G T Pase activity by adhesion molecules and mechanotransduction. K eithBur ridge, Elizabeth Lessey, Elizabeth Monaghan-Benson and Christophe Guilluy, Cell andDevelopmental Biology, Lineberger Comprehensive Cancer Center, and McAllister Heart Institute,University of North Carolina, Chapel Hill, NC 27599, USA. keith burridge@med.unc.eduSignaling in astrocyte migration induced by the neuronal protein T hy-1. Kong, M., Alvarez, A.Cárdenas, A., Quest, AFG. and L eyton, L. Laboratorio de Comunicaciones Celulares, Centro de EstudiosMoleculares de la Célula. Facultad de Medicina. Universidad de Chile. lleyton@med.uchile.clA dhesive and tensile interactions underlying individual and collective cell migration in vivo. GermánReig1,3, Eduardo Pulgar1,2,3, Felipe Santibañez2,3, Valeria Larenas1,3, Ricardo Figueroa1,3, SteffenHartell,2,3, M iguel Concha 1,3. 1Laboratory of Experimental Ontogeny – LEO and 2SCIAN-Lab, ICBM,Faculty of Medicine, University of Chile; 3Biomedical Neuroscience Institute, Santiago, Chile.mconcha@med.uchile.cl10:30 – 13:00Schools and Science: Students from Puerto V a ras at the C hilean Society for C ell BiologyRoom Business C enter11:00 – 13:00Poster V iewing Session I: 1-80 O dd NumbersConvention C enter FoyerCoordinators: Rebeca A ldunate – A ndrea Paula-L ima – M ario G alindo(1) Role of c-A bl in the processing of A PP and its implication in Niemann-Pick type C diseasemodels. Y añez M J 1,2, Alvarez AR1, Zanlungo, S2. 1Departamento de Biología Celular y Molecular,
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20126Facultad de Ciencias Biológicas. 2Departamento de Gastroenterología, Facultad de Medicina. PontificiaUniversidad Católica de Chile. myanezh@gmail.com(3) Synaptic plasticity induced by B D N F requi res R OS and RyR-mediated C a2 signals. A dasme T, Figueroa P, Bruna B, #Paula-Lima AC, ,§Hidalgo C. CEMC, BNI & §ICBM, F. Medicina, #F.Odontología, Universidad de Chile. tadasme@ciq.uchile.cl(5) RSV infects dendritic cells and changes tyrosine phosphorylation in T cell signaling molecules.C inthia A . A lvarez1 and Alexis Kalergis1,2. 1Millennium Institute on Immunology and Immunotherapy,Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, PontificiaUniversidad Católica de Chile. 2Departamento de Inmunología Clínica y Reumatología, Facultad deMedicina, Pontificia Universidad Católica. cinthialvarezm@gmail.com(7) T he F C fraction of immunoglobulin G attenuates the secretion of I L-10 by regulatory B cells.A ravena O, Ferrier A, Pino-Lagos K, Aguillón JC, Soto L, Catalán D. IRTGroup, Programa Disciplinariode Inmunología, ICBM, and Hospital Clínico, Universidad de Chile. aravena.octavio@gmail.com(9) Identification of Moloney M urine Leu kemia V i rus (M L V) p re-integration complex (PI C)interacting host cell p roteins. G loria A r riagada 1,2 and Stephen P. Goff1. 1Department of Biochemistryand Molecular Biophysics, Howard Hughes Medical Institute, Columbia University, New York, NY10032, USA. 2Departamento de Ciencias Biológicas, Universidad Andrés Bello, Campus Viña del Mar.gloria.arriagada@unab.cl(11) G alectin-8 is pro-fib rotic in human gingival fibroblasts. Pat ricio A vila, Anibal Romero A,Mónica Cáceres M, Patricio Smith, Andrea Soza, Alfonso González. Centro de Envejecimiento yRegeneración (CARE), Facultad de Ciencias Biológicas1. Departamento de Inmunología Clínica yReumatología2, y Odontología3, Facultad de Medicina. Pontificia Universidad Católica de Chile.pat.avila.p@gmail.com(13) Intracelula r localization of cereb ral dopamine neu rotrofic factor (C D N F). A nllely Fernández,Sheyla Guzmán, Yocelyn Cruz, Marysol Paz, Jorge Escobar, Pedro Zamorano*. Faculty of HealthSciences, University of Antofagasta, Chile. *zamorano@gmail.com(15) M icrotubule-associated protein 1B (M A P1B) regulates the establishment of p resynapticcontacts in vitro and interacts with the p resynaptic protein Snapin. Bodaleo F elipe1, MontenegroVenegas Carolina1, Hartel Steffen2 and González-Billault Christian1. (1)Laboratory of Cellular andNeuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile. (2)Laboratory forScientific Image Analysis, Faculty of Medicine, Universidad de Chile. bodaleo@gmail.com(17) A computational study of methods for estimating diffusion coefficient in frap experiments. L uisB riones1, Mauricio Cerda1, Jorge Toledo1,2, Omar Ramirez1, Takeshi Asahi3, Andres Couve2, and SteffenHärtel1. 1SCIAN-Lab, 2Couve-Lab, BNI, Faculty of Medicine, 3CMM, FCFM; U-Chile.lbriones@med.uchile.cl(19) M itochondrial and respi ratory effects of copper dep rivation in erythropoietic cells. RodrigoBustos, Lina Ruiz, Maria Isabel Lasso, Susana Grant and Alvaro Elorza. Experimental BioenergeticsLaboratory, Universidad Andres Bello. aelorza@unab.cl(21) Post-transductional cleavage of C-terminal tail of B M P receptor type I I in motor neu ron-likecells. Pila r C á rdenas1, Juan Pablo Henríquez2 and Nelson Osses1. 1Institute of Chemistry, P. CatholicUniversity of Valparaiso and 2Department of Cell Biology and CMA Bio-Bio, University of Concepción,Chile. cheerree@gmail.com(23) Small depola rization of muscle fibers induced by external A T P can activate IP 3-dependent C a 2 signals related to muscle plasticity. C asas, M ., Llanos, P. Hidalgo J., Jorquera, G., Buvinic S. andJaimovich, E. Centro de Estudios Moleculares de la Célula. ICBM, Facultad de Medicina, Universidad deChile. mcasas@med.uchile.cl
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20127(25) Increased angiogenesis in vitro induced by V E G F-A secreted from ca rcinoma-associatedstroma of invasive prostate cancer. Javier C erda-Infante1, Ignacio San Francisco2, Alejandro Godoy3,Gary Smith3, Viviana Montecinos1. 1Hematology-Oncology and 2Urology Departments, PontificiaUniversidad Católica de Chile. 3Urology department, Roswell Park Cancer Institute, Buffalo NY.jcerda.infante@gmail.com (Sponsor: M.A. García).(27) T r kB receptor induces the activation and nuclea r translocation of the ty rosine kinase c- A bl inhippocampal neu rons. C handía A .1,2 , Bronfman F.C3, Lazo OM3, Álvarez A.R1,2. 1Laboratorio deSeñalización Celular, 2CARE-Chile-UC, 3Departamento de Ciencias Fisiológicas, Pontificia UniversidadCatólica de Chile. america.chandia.c@gmail.com(29) E xp ression of dopamine receptor D3 on C D4 T-cells favors T h1 immunity. F ranciscoContreras1,2, Carolina Prado1,2, Hugo González1,2, Dafne Franz1, Daniela Elgueta1, Rodrigo Pacheco1.1Fundación Ciencia & Vida, 2Universidad Andrés Bello. crenovich@gmail.com(31) F unctional characterization of ca rgo binding sites on the μ2-subunit of adaptor proteincomplex 2. Esteban Corales, Yimo Lin, Patricia V. Burgos, Gonzalo A. Mardones. Instituto deFisiología, Facultad de Medicina, Universidad Austral de Chile. corales.esteban@gmail.com(33) E valuation of Synaptotagmin-I involvement in saliva ry gland hypofunction of Sjögren'sSyndrome patients. C haracterization of C a2 signaling in 3D acini. Cortés J, Hidalgo J, BahamondesV, Urra H, Barrera MJ, Castro I, Aguilera S, González S, Molina C, Leyton C, Urzúa U, Sepúlveda D andGonzález MJ. ICBM-Facultad de Medicina, Universidad de Chile. cortesjf@ciq.uchile.cl(35) A ltered exp ression of SL A M family receptors and thei r adaptor p roteins in lupus-p rone mice.N. C risóstomo1, A. Gleisner1, M. Rosemblatt1,2,3, M.R. Bono1. 1Departamento de Biología, Facultad deCiencias, Universidad de Chile. 2Fundación Ciencia &Vida. 3Universidad Andrés Bello.ncrisostomo@ug.uchile.cl(37) G alectin-8 regulates the homeostasis of T and B lymphocytes. C ristobal C u r kovic1,2*, EvelynPardo1,2*, David Valenzuela3, Alfonso González1,2 and Andrea Soza1,2. Centro de Envejecimiento yRegeneración (CARE), Fac. Ciencias Biológicas1. Departamento de Inmunología Clínica y Reumatología,Fac. Medicina2. Pontificia Universidad Católica de Chile. Regeneron Pharmaceuticals Inc, N.Y. USA3.*Pardo E. and Curkovic C. contributed equally to this study. epardo@uc.cl(39) Novel glucocorticoid-response elements in st2 distal p romoter a re responsible fortranscriptional activity in mast cells. Díaz-Jiménez D. 1, Sepúlveda H 2, Montecino M.2, Quera R.3,Hermoso MA1. 1Innate Immunity Lab, Immunology Program, ICBM, Faculty of Medicine, Universidadde Chile. 2Center for Biomedical Research and FONDAP Center for Genome Regulation, UniversidadAndres Bello. 3Gastronterology Unit, Clínica Las Condes, Chile. davordijim@gmail.com(41) G lucocorticoid receptor localization in the diabetic kidney. Romina Bertinat 1, Karen Jaramillo1,Pamela Silva1, Rodrigo Gatica1, Francisco Nualart2, Alejandro Yáñez1. 1Instituto de Bioquímica yMicrobiología, Universidad Austral de Chile. 2Departamento de Biología Celular y Centro de MicroscopíaAvanzada (CMA BIO-BIO), Universidad de Concepción. romibert@gmail.com(43) Effect of 5’-methylthioadenosine on C D4 T cell differentiation towards T reg and T h17 cells.C ristian Doñas, Macarena Fritz, Paz Reyes, Alejandra Loyola and Mario Rosemblatt. Fundación Cienciapara la Vida, Universidad Andrés Bello. c.donasc@gmail.com(45) M n-Superoxide dismutase modulates cytotoxicity induced by Senecio sp (Chachacoma) inbreast cancer cells under hypoxia. C arlos E chiburú-C hau, Cristian Salas, Mauricio Cuéllar, SusanaAlfaro, Juan Pablo Ogalde and Gloria Calaf. Instituto de Alta Investigación, Universidad de Tarapacá,Arica, Chile.cechiburu@uta.cl (Sponsor: G. Cabello).(47) Inflammation alters the exp ression of i ron transporters D M T1, FPN1 and Z IP14 in neurons,astrocytes and microglia. Urrutia P., Aguirre P., Esparza A. and Núñez MT. Department of Biology,Faculty of Science, University of Chile. andres.esparza@gmail.com
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 20128(49) Prima ry cilium ma r kers disappear as oligodendrocyte p recu rsor cells differentiate and becomeunresponsive to Shh. 1,2 Paulina F alcón U, 1Carlos Carrasco P, 1Alejandro Roth M. & 2Verónica PalmaA. Departamento de Biología, Facultad de Ciencias, Universidad de Chile. paulina.falcon.u@gmail.com(51) A ntioxidant activity of the Bios-p peptide analogue in H E K 293T cells. Pamela F ernández1,2,Ignacio Jofre1, Patricia Navarrete1, Magdalena Cuevas1, Ximena Romo2, Jorge Parodi3, FernandoRomero1. 1Center of Neurosciences and Peptides Biology- CEBIOR-BIOREN-CEGIN, Universidad de LaFrontera, Temuco, Chile. 2Departamento de Ciencias Biológicas, Facultad de Ciencias Biologicas,Universidad Andres Bello, Sede Concepción, Chile. 3Laboratorio de Fisiología de la Reproducción,Núcleo de Producción Alimentaria, Escuela de Medicina Veterinaria, Facultad de Recursos Naturales,Universidad Católica de Temuco, Temuco, Chile. pamelafernm@gmail.com(53) G alectin-8 expression and chemotherapeutic drug resistance in ova ry cancer cells. F elipeG aray1,2,3 , Felipe Leiva3, Alfonso Gonzalez1,2, Andrea V. Leisewitz3, Andrea Soza1,2. Centro deEnvejecimiento y Regeneración (CARE)1, Facultad de Ciencias Biológicas, Departamentos deInmunología Clínica y Reumatología2 y Hematología-Oncología3, Facultad de Medicina, PontificiaUniversidad Católica de Chile. figaray@uc.cl(55) Bci-1: a new tissue specific, negative regulator of autophagy. G herardelli C 1, Vicencio E1,Matamala JM2, Rojas M1, Hetz C2, and Manque P1. 1Center for Genomics and Bioinformatics,Universidad Mayor, 2Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Chile.Patricio.manque@umayor.cl(57) A LS ast rocytes release factors that trigger c-A bl phosphorylation in motoneu rons: role ofsodium channel activity and oxidative st ress. David Gonzalez1, Fabiola Rojas1,2, Elsa Fritz1,2, AlexisMartinez3, Sebastian Abarzua1, Nicole Cortes1, Alejandra Alvarez3, Brigitte van Zundert1. 1Andrés du(59) Participation of monoclonal antibodies in detection and study of RSV-induced pathogenesisthrough FcγRs. Roberto Gómez1, Kelly Cautivo1 and Alexis Kalergis1,2. 1Millennium Institute onImmunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad deCiencias Biológicas, Pontificia Universidad Católica de Chile. 2Departamento de Inmunología Clínica yReumatología, Facultad de Medicina, Pontificia Universidad Católica. rsgomezj@gmail.com(61) Pola rization of C x43 towa rds the immunological synapse induces N K -mediated tumor celldeath by granzyme-B and calcium dependent mechanisms G uer rero I., Tittarelli A., MendozaNaranjo A., Farías M., Salazar-Onfray F. Tumor Immunology Laboratory, Faculty of Medicine,University of Chile. israel.biologo@hotmail.com(63) N-terminus domain cont ributes to thermal and chemical sensitivity of T RPM8 channel. H ardy,P.1, van Zundert, B.2, Madrid, R.1, Viana, F.3 and Pertusa, M.1. 1Departamento de Biología, Facultad deQuímica y Biología, Universidad de Santiago de Chile. 3Centro de Investigaciones Biomédicas,Universidad Andrés Bello, 2Instituto de Neurociencias de Alicante, UMH-CSIC, España.maria.pertusa@usach.cl(65) T wo-dimensional elect rophoresis of different culture conditions of the fish pathogenStreptococcus phocae . C h ristian H idalgo, Rodolfo Paredes, Julio Retamales and Rubén AvendañoHerrera. Universidad Andrés Bello. chissock@gmail.com(67) A dult guinea pig brain has a lateral ventricle extention involved in neurogenesis. Jara, N.,Rodríguez, F., Oyarce, K. and Nualart, F. Neurobiology and Stem Cells Laboratory, Department of CellBiology, University of Concepción. neryalejara@udec.cl(69) E valuation of a C hilean ext ract of Ugni molinae Turcsz, generator of vasodilation in rat aortasand antioxidant effect in C R L1730 cell line. Ignacio Jofré1 , Javier Retamal1, Erick Scheuermann2,Jorge Parodi3, Fernando Romero1. 1Center of Neurosciences and Peptides Biology-BIOREN-UFRO.
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 201292Center of Food Biotechnology and Bioseparations-BIOREN-UFRO,3Laboratory of ReproductivePhysiology, UCT. ignaziojf@gmail.com(71) E xp ression and pola rized dist ribution of the cell su rface p rotein ta rget of anti-P autoantibodiesfrom lupus patients. A ngel Ju rado-Tor res1,2, Fabián Segovia1,2, Marcela Bravo-Zehnder M 1,2, CarlosCéspedes2,3, Carlos Vio2,3, Loreto Massardo L1, David Valenzuela3, and Alfonso González 1,2.Departamento de Inmunología Clínica y Reumatología, Facultad Medicina1. Centro de Envejecimiento yRegeneración2 and Departamento de Fisiología3, Fac. Ciencias Biológicas. Pontificia UniversidadCatólica de Chile. Regeneron Pharmaceuticals Inc, N.Y. USA3. angel.juradot@gmail.com(73) T hymic st romal lymphopoietin is produced by human metapneumovi rus-exposed humanairway epithelial cells. M arga rita K . L ay, Pablo Céspedes, Alexis M. Kalergis. 1Millennium Institute onImmunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad deCiencias Biológicas, 2Departamento de Reumatología, Facultad de Medicina, P. Universidad Católica deChile. mlay@bio.puc.cl(75) Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system.Lopez-V er rilli M . A .1, Court F.A.1,2. 1Millennium Nucleus in Regenerative Biology, Catholic Universityof Chile and 2Neurounion Biomedical Foundation. alejanddra@gmail.com, fcourt@bio.puc.cl(77) Plasticity of T reg and T h17 cells during immune response and tolerance induction. G . Tejón 1,2,V. Manríquez1, J. R. Mora2, M.R. Bono1, M. Rosemblatt1,3,4. 1Departamento de Biología, Facultad deCiencias, Universidad de Chile. 2Gastrointestinal Unit, Massachusetts General Hospital, Harvard MedicalSchool. 3Fundación Ciencia & Vida. 4Universidad Andrés Bello. gabriela tejon@yahoo.com(79) T he kynase c-A bl is activated in A myot rophic L ateral Sclerosis motor neu rons and pa rticipatesin neurodegeneration in the SO D1 G86R mice. A lexis M artínez1,2, Cristián Valls1,2, Brigitte VanZundert3, Claudio Hetz4, Alejandra Álvarez1,2. 1Laboratorio de Señalización Celular, 2CARE-Chile-UC,Pontificia Universidad Católica de Chile. 3Center for Biomedical Research. University Andres Bello.4Laboratory of Cellular Stress and Biomedicine, University of Chile. amartin1@uc.cl13:00 – 14:00Plena ry Lectu re Sociedad de Biologia C elula r de C hileVolcanes RoomC hair: C hristian Gonzalez-BillautRegulation of memb rane p rotein t rafficking during neu ronal pola rization. A lfredo C áceres,Instituto Investigación Médica Mercedes y Martin Ferreyra (Inimec-Conicet), Universidad Nacional deCordoba, Argentina.14:00 – 15:30L unch15:30 – 16:30Plena ry Lectu re C entro de Investigaciones Biomédicas y C entro F O N D A P de Regulación delG enoma, Universidad Nacional A nd res BelloVolcanes RoomC hair: G iancarlo de Fer ra riThe genetics of Parkinson’s disease: moving from va riant to function. A ndrew Singleton. Laboratoryof Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA. (for theInternational Parkinson’s Disease Genomics Consortium) singleta@mail.nih.gov16:00 – 18:30Schools and Science: Students from Puerto V a ras at the C hilean Society for C ell BiologyRoom Business C enter16:30 – 18:30Poster V iewing Session I: 1-80 E ven NumbersConvention C enter FoyerCoordinators: M arcela B ravo – G areth O wen – Rodolfo Pa redes
Chilean Society for Cell Biology – XX VI Annual Meeting – October 23-27, 201210(2) Reprimo, a potential biomar ker for p rospective clinical t rial in gast ric cancer. M aturana M J.,Olivares W., Garcia E., Torres V., Padilla O., Aguayo F., Calvo A., Ferreccio C., Corvalán AH. PontificiaUniversidad Católica de Chile. mmaturanar@med.puc.cl(4) C ardiac Rho kinase activation ea rly after experimental acute myoca rdial infa rction. C laudiaM era, María Ocaranza, Renato Ramírez, Soledad Veliz, Iván Godoy, Jorge Jalil. Departamento deEnfermedades Cardiovasculares, Laboratorio de Cardiología Molecular, Escuela de Medicina, P.Universidad Católica de Chile. claudiamera@gmail.com (Sponsor: S. Lavandero).(6) Jitterbug(jbug)/F ilamin and protein tyrosine phosphatase 69D (PT P69D) are required fo rtendon cell adaptation to mechanical stress and axon growth. C laudia Molina and Patricio Olguín.Programa de Genética Humana, ICBM, Facultad de Medicina, Universidad de Chile.claudiavetera@gmail.com(8) Role of Panx1 hemichannels in the secretory activity of neuroendocrine ch romaffin cells. F annyMomboisse1 , Catherine Estay1, María J. Guerra1, Ximena Baéz1, Juan C. Saez2, Agustin D. Martínez1 andAna M. Cárdenas1. Centro Interdisciplinario de Neurociencias de Valparaíso, 1Universidad de Valparaíso,Valparaíso, and 2Departamento de Fisiología, P. Universidad Católica de Chile, Santiago.fanny.momboisse@cinv.cl(10) Release of gliotransmitters th rough astroglial connexin 43 hemichannels is necessa ry for fea rmemory consolidation in the basolateral amygdala. Jimmy Stehberg, Rodrigo Moraga-A ma ro,Cristián Salazar, Álvaro Becerra, Cesar Echeverría, Juán Andrés Orellana, Geert Bultynck, Raf Ponsaerts,Luc Leybaert, Felipe Simon, Juán Carlos Sáez, Mauricio Retamal. Universidad Nacional Andrés Bello(Chile), Universidad del Desarrollo (Chile), Pontificia Universidad Católica de Chile (Chile), KatholiekeUniversiteit Leuven (Belgium), Ghent University (Belgium). rod.moraga@uandresbello.edu(12) A ctivation of signalling pathways in response to spinal cord injury in Xenopus. M auricioMoreno1, Dasfne Lee1, Leonardo Almonacid2, Francisco Melo2, Juan Larraín1 . 1Center for Aging andRegeneration and Millennium Nucleus in Regenerative Biology 2Molecular Bioinformatics Laboratory,Millennium Institute on Immunology and Immunotherapy. Pontificia Universidad Católica de Chile.mmoreno@bio.puc.cl(14) I L-6 muscle levels a re elevated in cachexia using a murine model of ca
Chilean Society for Cell Biology - XXVI Annual Meeting - October 23-27, 2012 2 TUESDAY, OCTOBER 23, 2012 09:00 - 13:00 Registration Convention Center Foyer 11:30 - 12:30 Technical Lectures - Calbuco Room MBF Bioscience Inc. and Arquimed Cuantificación Celular por Estereología y Reconstrucción Neuronal en 3D
