Transcription
PerkinElmer Series 200HPLC Systemsdesigned tonever let you down
an inside look at theSeries 200 HPLC systemsPerkinElmer knows you need to rely on your highperformance liquid chromatography (HPLC) systemto get the job done day-in and day-out. That’s whywe designed and built the Series 200 family of HPLCinstruments.We’re confident the Series 200 HPLC family will meetand exceed the liquid chromatography demands of yourlab, because each component – from pump to data handling – has proven track records behind them. Best of all,all of our systems are backed by our renowned globalservice and support organization, so you know you candepend on them today, tomorrow and for years to come.The brains behind the brawn –TotalChrom CDSAcquiring, processing, reporting, reviewing andapproving data is a streamlined series of operationsin PerkinElmer ’s TotalChrom Chromatography DataSystem (CDS) software, designed to fit your laboratoryworkflow and maximize productivity. With its scalablearchitecture, 21 CFR Part 11 compliance features andproven algorithms, TotalChrom offers a computingstrategy to manage your chromatography data quicklyand securely in both regulated and non-regulatedenvironments. TotalChrom data systems can bedeployed in standalone, thin client, or enterpriseclient/server computing environments.SoftLINK : entry-level solution forinstrument connectivityDesigned for one instrument, workstationenvironments, SoftLINK provides instrumentconnectivity at a glance.dotLINK : interfacing with easedotLINK is a Windows CE-based interfacethat allows you to connect your Series 200directly to the network. Designed to facetoday’s workload challenges and provideEthernet connectivity, dotLINK allows externalbuffering with a minimal need for validation.2
rugged and reliable – theSeries 200 Analytical PumpDesigned to work in applications where minimaldowntime and low maintenance are a must, theproven, rugged design of the Series 200 AnalyticalPump offers low piston wear for less downtime andlower cost of ownership.Precise blending through advanced engineering isobtained by the Series 200 using a design that allowsautomatic compensation of solvent compressibilityduring each pump stroke. This feature plus two-pointflow calibration ensure greater accuracy, highly-preciseflow rates, and high-performance gradient capability.True mixing volume correction using the chemist’sapproach is obtained precisely and reliably, run after run.That is why thousands of laboratories worldwidehave chosen to rely on PerkinElmer’s unique pumping technology.Low, precise microflows –the Series 200 Micro PumpThe Series 200 Micro Pump, with its ultra-low delayvolume, is ideal for narrowbore chromatography –or as a front-end to your LC/MS. The Series 200 MicroPump offers superior flow rate precision, compositionalaccuracy, and retention-time precision for either isocraticor gradient separations. The Series 200 Micro Pump isavailable in isocratic or binary high pressure blendingwith user customizable mixing. Whenever “no delayvolume” and “ultra-fast gradient” are required, the Series200 Micro Pump is the solution for your applications.Growing platform to match your needsPumps can be upgraded to additional solventcapabilities right in your lab. Start with a simpleisocratic and expand to binary or quaternaryto match your needs.w w w. p e r k i n e l m e r. c o m3
fast, accurate and flexible –theSeries 200 AutosamplerNeed speed? Reliability? Flexiblesampling? The Series 200 Autosamplerdoes it all!The Series 200 Autosampler rapidly brings the needleto the sample, eliminating the time, complexity andunreliability of moving sample vials, while providingsupport for numerous sample container formats. Selectyour injection volume, needle height and flush cyclesto be able to analyze every sample in the most suitableanalytical conditions.The fast, flexible and ultra-reliable sampling – up tothree injections per minute – is due to the unique, allgear-driven drive mechanism.Key features Advanced design for injection valve flushing andexternal needle wash reduces carryover – offersa 0.005% carryover specification. Impressive injection linearity for uncompromisedquantitative analysis and method development. Boasts the industry’s best on-board automatedderivatization/dilution performance of anyanalytical autosampler. It is now easy and takeslittle time to prepare solutions for calibrationcurves and internal standard (ISTD) addition. Easily interchangeable, cost-effective sampletrays. Choose from over 13 different tray/sampling formats. High-capacity sample trayscan accommodate up to 225 vials or two 96- ortwo 384-well plates with full control of needlelevel within sample vials/trays and on-boardtemperature control.
precise for increased repeatability –Column OventheSeries 200The PerkinElmer Series 200 Column Oven controls themobile phase and sample temperature before enteringthe column via a low dispersion built-in pre-heater.This eliminates thermal gradients across the column,resulting in better column performance and preciseretention times. All heating and cooling is performedelectronically, permitting sub-ambient temperatureswithout coolant or refrigerants.solubility, resulting in better resolution and/or increased speed of analysis. Sub-ambient temperaturecapabilities are helpful in many biomolecular analysesand in the analysis of some chiral compounds.By maintaining the column temperature at a stableset point, more standardized resultscan be obtained, permitting betterday-to-day and lab-to-lab comparison of results. In addition, elevated temperatures can be usedin many applications to decreasemobile phase viscosity while increasing mass transfer and samplew w w. p e r k i n e l m e r. c o m5
Series 200Getting answers not just data –the Series 200 PDAStable and ready for any challenge –the Series 200 UV/Vis DetectorThe Series 200 Photo Diode Array (PDA) Detector,provides true UV/Vis detection and high resolutionspectral data. The Series 200 PDA is fully networkcompatible, providing fast and secure transmissionof chromatographic and spectral data.The Series 200 UV/Vis Detector is a solid foundationfor your total HPLC system, offering the highest sensitivity and outstanding linearity performance – evenat extremely high or low concentrations – 24 hours-a-day,seven days-a-week.The excellent signal-to-noise characteristics of theSeries 200 Diode Array make it ideally suited forlow volume or low concentration samples. In addition,the spectral data generated by the Series 200 is quicklyand easily processed by our powerful IRIS SpectralProcessing Software developed by PerkinElmer. It offersa full suite of functionality and an intuitive user interface, all protected under a fully 21 CFR Part 11 compliant architecture.Key features The Series 200 UV/Vis supports the full UV/Visrange from 190 to 700 nm Several flow cell formats to choose from tomeet your specific application requirements inanalytical, semi-prep or micro-bore environments.6
family of detectorsRugged and easy-to-use –the Series 200 Refractive IndexCombining sensitivity and specificity –the Series 200 FluorimeterThe Series 200 Refractive Index (RI), with its deflectiontype design, allows sensitive detection of these compounds with low noise and drift characteristics. Thisadvanced detector features internal temperature controlof the flow cell, offset adjustment, autozero, and autopurge of the reference cell – all with easy keypad entry.An intuitive, built-in Graphical User Interface allowsauto calibration and extended diagnostic plus visualization of the real time signal during and between runs.The Series 200 RI Detector is a highly stable and sensitive LC and GPC detector for use with compoundsthat do not have high absorption in the UV range, suchas polymers, sugars, organic acids and triglycerides.The Series 200 Fluorescence Detector delivers theoutstanding performance and reliability you’ve cometo expect from PerkinElmer. Although retention timeis the main tool for identification of analytes, thecomplexity of real world samples requires the confirmation of peak identity through additional qualitativeinformation. The major benefit afforded by fluorescence detection is the inherent high sensitivity of thetechnique coupled with outstanding specificity – giventhat relatively few molecules natively fluoresce. Therefore, the specific excitation and emission wavelengthprofile aids in the characterization of individualcomponents. The Series 200 Fluorimeter far exceedscommon standards of sensitivity. It is a necessarytool for the most demanding environmental, lifescience and food safety applications.w w w. p e r k i n e l m e r. c o m7
PerkinElmer, Inc.There for the installation – and beyond.The Series 200 HPLC modules and TotalChrom providean integrated solution to your most demanding applica-Expand your field of applications: discover thePerkinElmer’s Radio-Flow detection technology:Radiomatic 150TRtion requirements. From getting a new product to marketThe Radiomatic 150TR is a complete flow scintillationto performing routine QA/QC analysis, the Series 200analyzer that is optimized for monitoring single- or dual-HPLC systems powered by TotalChrom will help youlabeled radioisotopic samples separated by liquidto streamline your laboratory workflow. Best of all,chromatography. The Radiomatic 150TR detectorPerkinElmer also has the know-how and resourcesplatform uses state-of-the-art scintillation countingto deliver best-in-class service from initial setuptechnology and can be used as a stand-alone detectorand installation to preventive maintenance.with on-board chromatography data reduction orintegrated into the Series 200 system.Discover PerkinElmer’s high-throughput instrumentation offerings: JANUS Automated WorkstationThe JANUS Automated Workstation provides enhancedproductivity and adaptability opportunities to meet thedemanding needs of pharmaceutical, biotech and research customers. A scalable automated workstation,JANUS employs a modular design enabling the additionand replacement of liquid handling and labware movementtechnologies as application and throughput demands evolve.JANUS is available in three platforms – Standard,Expanded and Integrator models. Each platform can beconfigured with a choice of pipetting modules to addressthroughput requirements and labware movement arms forwalk-away capability. As application demands change,JANUS Automated WorkstationJANUS’ modularity allows system upgrades accordingly.WinPREP for JANUS application software provides theflexibility required for various laboratory applicationswithout adding time-intensive programming complexity.PerkinElmer Life andAnalytical Sciences710 Bridgeport AvenueShelton, CT 06484-4794 USAPhone: (800) 762-4000 or( 1) 203-925-4602www.perkinelmer.comFor a complete listing of our global offices, visit www.perkinelmer.com/lasoffices 2005 PerkinElmer, Inc. All rights reserved. The PerkinElmer logo and design are registered trademarks of PerkinElmer, Inc. dotLINK, IRIS, Janus and SoftLINK are trademarksand PerkinElmer, TotalChrom and WinPrep are registered trademarks of PerkinElmer, Inc. or its subsidiaries, in the United States and other countries. All other trademarks notowned by PerkinElmer, Inc. or its subsidiaries that are depicted herein are the property of their respective owners. PerkinElmer reserves the right to change this document at anytime without notice and disclaims liability for editorial, pictorial or typographical errors.007370 01Printed in USA
the Series 200 UV/Vis Detector The Series 200 UV/Vis Detector is a solid foundation for your total HPLC system, offering the highest sen-sitivity and outstanding linearity performance - even at extremely high or low concentrations - 24 hours-a-day, seven days-a-week. 6 Key features The Series 200 UV/Vis supports the full UV/Vis
