Cell Division And Growth Control - Drosophila-conf

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PLATFORMPOSTER SESSIONSSESSIONS37Poster board numberis innumberbold abovetitle.aboveSee pagefor presentationschedule.first authoris the presenter.Abstractsbegin on page 79.Programis intheboldthe 7title.The first authoris theThepresenter.Abstractsbegin onpage 79.Cell Division and Growth Control137AThe Drosophila Kinesin 6 family member Subito has a role inmitotic spindle assembly. Janet Jang, Jeffry Cesario, EricaKolibas, Kim McKim. Waksman Inst, Rutgers Univ,Piscataway, NJ.138BGenetic analyses of dE2F1 regulation in vivo. Jun-yuan Ji,Anabel Herr, Nicholas Dyson. Mass General Hosp CancerCtr, Charlestown, MA.139Chumpty dumpty is required for genome integrity duringcleavage divisions in the Drosophila embryo. YehoshevaMarkovitz-Landau, Jennifer Bandura, Mi-Young Cho, BrianR. Calvi. Dept Genetics, Univ Pennsylvania Sch Medicine,Philadelphia, PA.140AEssential role of Drosophila MEK in the control of cell cycleprogression and midblastula transition. Vladic A. Mogila1,2,Willis Li1. 1) Dept. of Biomedical Genetics and J.P. WilmotCancer Center of the University of Rochester Medical Center,Rochester, NY; 2) Institute of Gene Biology, Russian Academyof Sciences, Moscow, Russia.141BNUP98/96- key to germ line stem cell divisions and stem cellniche formation. Angshuman Sarkar, Yuting Chiang, StephenHearn, Cordula Schulz. Cold Spring Harbor Laboratory, ColdSpring Harbor, NY.142CDrosophila mars regulates spindle checkpoint. Ching-Po Yang,Seng-Sheen Fan. Life Science, Tunghai University, Taichung,Taiwan.143AAn investigation of somatic pairing in Drosophila embryos.Justin Blumenstiel, R. Scott Hawley. Stowers Institute forMedical Research, Kansas City, MO.144BA Model for How Heterochromatin Maintains Pairing in NonExchange Chromosomes. William Gilliland, R. Scott Hawley.Stowers Inst, Kansas City, MO.145CSynaptonemal complex assembly requires the N- and Cterminal domains of the transverse filament protein C(3)G.Jennifer K. Jeffress1, Lorinda K. Anderson2, Scott L. Page1,R. Scott Hawley1. 1) Stowers Inst, Kansas City, MO; 2) ColoradoState Univ., Fort Collins, CO.146AHold’em reveals a link between the meiotic crossover pathwayand oocyte differentiation. Eric Joyce, Kim McKim. WaksmanInst, Rutgers Univ, Piscataway, NJ.147BThe minichromosome maintenance complex protein Mcm5plays critical roles in meiotic recombination in Drosophila.Cathleen M. Lake, R. Scott Hawley. Stowers Institute forMedical Research, Kansas City, MO.148CAn analysis of new meiotic mutants in Drosophila from agermline clone screen. Rachel Nielsen, Scott Page, CathleenLake, Kathy Teeter, SengKai Ong, Kathleen Lindstrom,Kristen Dean, Jennifer Samson, William Gilliland, R. ScottHawley. Scott Hawley Lab, Stowers Inst, Kansas City, MO.149AThe Physical Basis of Secondary Nondisjunction (XX - YSegregation): The X and Y chromosome Paired During EarlyMeiotic Prophase and This Pairing Is Maintained UntilPrometaphase in the Absence of X chromosomal Exchange.Youbin Xiang, R. Scott Hawley. Stowers Inst MedicalResearch, Kansas City, MO 64110.150BOnset of CHK1 activity is regulated by Cdk1-Cyclin B doses.Justin Crest, Nate Oxnard, Gerold Schubiger. Dept Biol, UnivWashington, Seattle, WA.151CDivision of specific subgroups of PNS precursor cells requiresTRIM protein cell cycle regulatory activity. Fergal O’Farrell1,2,Per Kylsten1. 1) Natural Sciences, Södertörns UniversityCollage, Stockholm, Sweden; 2) Medical Nutrition, KarolinskaInstitute, Stockholm, Sweden.152ATousled-like kinase functions in G2/M progression. Hsiao-HsiGash Chou2, Gwo-Jen Liaw1,2. 1) Faculty of Life sciences; 2)Institute of Genomic Science, National Yang-Ming University,Taipei, Taiwan.153BMitotic activation of the kinase Aurora-A requires its bindingpartner Bora. Andrea Hutterer1, Daniela Berdnik2,3, AlexSchleiffer2, Juergen A. Knoblich1. 1) Institute of MolecularBiotechnology (IMBA), Vienna, Austria; 2) Institute of MolecularPathology (IMP), Vienna, Austria; 3) Department of BiologicalSciences, Stanford University, Stanford, CA.154CCyclin A is an in vivo regulator of the Drosophila Myb protein,affecting its various roles in cell cycle regulation. Jennifer A.McEllin, Siau-Min Fung, George S. Scaria, Gary Ramsay,Alisa L. Katzen. Biochem and Mol Genetics, University ofIllinois-Chicago, Chicago, IL.155AGenetic and biochemical approach to study regulation ofSecond Mitotic Wave. Abhishek Bhattacharya, Lucy Firth,Nicholas E. Baker. Molecular Genetics, Albert EinsteinCollege of Medicine, Bronx, NY.

38POSTER SESSIONSPoster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.156BDevelopmental control of cell cycle exit in Drosophila. LauraA. Buttitta, Bruce Edgar. Basic Sciences, Fred HutchinsonCancer Research Center, Seattle, WA.157CTemporal growth regulation by the Drosophila microRNA let7. Elizabeth E. Caygill, Eri Yoshida, Laura A. Johnston.Department of Genetics & Development, College of Physicians& Surgeons, Columbia University, New York, NY.158AIdentifying Novel Cell Cycle Regulators in the Drosophila Eye.Lucy C. Firth, Nicholas E. Baker. Molecular Genetics, AlbertEinstein College Med, Bronx, NY.159BThe Drosophila calcipressin homolog, sarah, is required forseveral aspects of egg activation. Vanessa Horner1, AndreasCzank2, Janet Jang3, Navjot Singh4, Byron Williams1, JaakkoPuro5, Eric Kubli2, Steven Hanes4,6, Kim McKim3, MarianaWolfner1, Michael Goldberg1. 1) Dept Molec Biol & Genetics,Cornell University, Ithaca, NY; 2) Institute of Zoology, Univ ofZürich, CH-8057, Switzerland; 3) Waksman Institute & DeptGenetics, Rutgers, Piscataway N.J; 4) Molec GeneticsProgram, Wadsworth Center, New York State Dept of Health,Albany, NY; 5) Dept of Biology, Univ of Turku, SF-20500,Finland; 6) Dept Biomedical Sciences, School of Public Health,SUNY, Albany, NY.160CDifferential DNA Replication as a Developmental Strategy inDrosophila. Jane C. Kim, Helena Kashevsky, Ryan Casillo,Eugenia Park, Terry L. Orr-Weaver. Whitehead Institute andDepartment of Biology, MIT, Cambridge, MA.161AMicroRNA miR-7 regulates germline stem cell divison. S. H.Reynolds, S. D. Hatfield, H. R. Shcherbata, H. Ruohola.Biochemistry, University of Washington, Seattle, WA.162BDown-regulation of Notch signaling is required for the switchfrom the genomic to site-specific DNA replication in Drosophilafollicle cells. Jianjun Sun, Wu-Min Deng. Dept Biological Sci,Florida State Univ, Tallahassee, FL.163CThe leucine zipper transcription factor Bunched regulatesfollicle cell proliferation and morphogenesis. Xiaodong Wu1,Megumu Mabuchi1, Erick Morris 2, Nick Dyson2, LaurelRaftery 1. 1) Cutaneous Biology Research Center, MGH/Harvard Medical School, Charlestown, MA; 2) MGH CancerCenter, MGH/Harvard Medical School, Charlestown, MA.164ARegulation of centrosome duplication by simian virus 40protein small tumor antigen. Shaila Kotadia 1 , SarahComerford2, Robert Hammer2, Tim Megraw1. 1) Departmentof Pharmacology and the Green Center for ReproductiveBiology Science, The University of Texas SouthwesternMedical Center, Dallas, TX; 2) Department of Biochemistryand the Green Center for Reproductive Biology Science, TheUniversity of Texas Southwestern Medical Center, Dallas, TX.165BPOLO kinase regulates the Drosophila centromere cohesionprotein MEI-S332. Astrid Clarke, Helena Kashevsky, TerryOrr-Weaver. Dept Biol, Whitehead Inst, MIT, Cambridge, MA.166CA nuclear complex of proteins that forms a spindle matrix duringmitosis in Drosophila. Yun Ding, Hongying Qi, Uttama Rath,Lei Zhu, Jack Girton, Jorgen Johansen, Kristen Johansen.Biochem, Biophys & Molec Biol, Iowa State Univ, Ames, IA.167AIdentifying Atg1 Interacting Proteins in Drosophila. Yu-YunChang, Thomas Neufeld. MCDB&G, University of Minnesota,Minneapolis, MN.168BThe Drosophila Tsg101 ortholog is required cell autonomouslyto maintain epithelial cell polarity and growth control. M.Melissa Gilbert, Kenneth H. Moberg. Department of CellBiology, Emory University, Atlanta, GA.169CMutations in the novel gene gang of four deregulate growth inthe Drosophila eye. Carolyn A. Krisel, Kenneth H. Moberg.Department of Cell Biology, Emory University School ofMedicine, Atlanta, GA.170ACharacterization of Drosophila Lnk – an adaptor proteininvolved in growth control. Christian Werz, Hugo Stocker,Ernst Hafen. Department of Zoology, University of Zürich,Zürich, Switzerland.171BD. melanogaster pupal development: Looking behind the chitincurtain. Thomas Donndelinger, Elizabeth Oldenkamp. BiBiomics, Mercy Medical Center, Nampa, ID.172CNeuroendocrine Growth Control by Activin/TGF-β-TypeLigands in Drosophila. Theodor E. Haerry, Scott C. Gesualdi.Department of Biological Sciences, Florida Atlantic University,Boca Raton, FL 33431.173AThe role of compartments in the growth of the wing imaginaldisc. Marcus L. Vargas, Meng-Ping Tu, Laura A. Johnston.Department of Genetics and Development, College ofPhysicians & Surgeons, Columbia University, New York, NY.

POSTER SESSIONS39Poster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.174BImaginal disc regeneration: linkage between cell death andorgan growth. Brent Wells, Laura A. Johnston. Dept Genetics& Development, Columbia Univ, New York, NY.175CDmWWOX, a WW domain containing oxidoreductase, protectsagainst the effects of ionizing radiation and interactsgenetically with Dmp53. Louise O’Keefe1, Yinghong Liu1,Alison Perkins1, Sonia Dayan1, Robert Saint1,2,3, RobertRichards 1,2. 1) ARC Special Research Centre for theMolecular Genetics of Development; 2) ARC-NHMRCResearch Network in Genes and Environment inDevelopment, School of Molecular and Biomedical Sciences,The University of Adelaide, Adelaide S.A. 5005, Australia; 3)Research School of Biological Sciences, Australian NationalUniversity, Canberra, ACT 2601, Australia.176ADrosophila FOG homolog U-shaped is a hematopoietic tumorsuppressor. Richard Sorrentino, Tsuyoshi Tokusumi, MarkRussell, Kathleen Gajewski, Robert Schulz. BioChem/MolecBiol, Univ Texas, MD Anderson Can Ctr, Houston, TX.177BIdentification of factors mediating cell competition in D.melanogaster. Claire de la Cova, Laura A. Johnston. Genetics& Development, Columbia University, New York, NY.178CEstablishment of a cell-culture based cell competition assaysystem using Drosophila cells for a functional genomewideanalysis. Nanami Senoo-Matsuda, Laura A. Johnston. DeptGenet & Dev, Coll. P & S, Columbia Univ, New York, NY.179ACyclin J is required for normal oocyte development.Govindaraja Atikukke1, Russell L. Finley, Jr.1, 2. 1) Departmentof Biochemistry and Molecular Biology, Wayne State University,Detroit, MI; 2) Center for Molecular Medicine and Genetics,Wayne State University, Detreoit, MI.180BDacapo promotes the licensing of DNA replication originsduring Drosophila endocycles. Mary Lilly1, Amy Hong1, KarineNarbonne1, Haiquing Fu2, Mirit Aladjem2. 1) Cell Biology &Metabolism Branch, NICHD/NIH, Bethesda, MD 20892; 2)Laboratory of Molecular Pharmacology, NCI /NIH, Bethesda,MD 20892.181CDissection of Condensin Structure. Xiao-Jun Wang, Tom Hartl,Paula Campbell, Gio Bosco. Department of Molecular &Cellular Biology, University of Arizona, Tucson, AZ.Cytoskeleton and Cellular Biology182AThe membrane lipid Phosphatidylinositol-3-phosphate (PtdIns(3) P) is involved in Drosophila wing hair formation. MasatoAbe 1 , Reiko Kuwahara 1 , Shuka Haragushi 1 , IsamuKusaka1,3, Wakae Awano1, Kuniaki Takahashi2, Ryu Ueda2,Satoshi Goto1,3. 1) Mitsubishi kagaku institute of life science,Mashida, Tokyo, Japan; 2) National institute of genetics,Mishima, shizuoka, Japan; 3) PRESTO.183BUnc104 transports neuropeptide vesicles but not mitochondriain motor neurons. Rosemarie Barkus 1, Olga Klyachko1,Aaron Pilling3, Barry Dickson2, William Saxton1. 1) BiologyDepartment, Indiana University, Bloomington, IN; 2) ResearchInstitute of Molecular Pathology (IMP) 1030 Vienna, Austria;3) University of Pennsylvania School of MedicinePhiladelphia, PA 19104-6085.184CSperm tail formation in Drosophila requires PIP2. Julie A.Brill 1, Ho-Chun Wei1, Gordon Polevoy1, Janet Rollins2,Christopher Bazinet2. 1) Developmental Biology, The Hospitalfor Sick Children, Toronto, Ontario, Canada; 2) BiologicalSciences, St. John’s University, Jamaica, NY.185AEna promotes actin filament elongation during epithelialmorphogenesis. Julie Gates1, James P. Mahaffey1, Frank B.Gertler2, Mark Peifer1. 1) Lineberger Cancer Center, UNCChapel Hill, Chapel Hill, NC; 2) Dept of Biology, MIT,Cambridge, MA.186BDiaphanous is an important regulator of Drosophilamorphogenesis. Catarina F. Homem, Rachel B. Hauser, MarkPeifer. Dept Biol, Univ North Carolina, Chapel Hill, NC.187Cβ-tubulin 85D is required for cell shape changes duringembryonic salivary gland development. Rakhi Jattani, MonnMonn Myat. Weill Medical College of Cornell University, NewYork, NY 10021.188AEna is required for cortical and cytoplasmic actin networks innurse cells during oogenesis. James P. Mahaffey 1, JulieGates1, Frank B. Gertler2, Mark Peifer1. 1) Lineberger CancerCenter, UNC-CH, Chapel Hill, NC; 2) Dept. of Biology, MIT,Cambridge, MA.189BUsing Drosophila to identify human genes critical for cellmigration. Li-Mei Pai, I-Ching Lee, Chin-Wen Yang. DeptBiochem & Molecular Biol, Chang-Gung, Tao-Yuan, Taiwan.

40POSTER SESSIONSPoster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.190CRegulated and polarized accumulation of PtdIns(3,4,5)P3 isessential for morphogenesis of the apical membrane inphotoreceptor epithelial cells. Franck Pichaud1, Deborah C.I. Goberdhan2, Lucy Collinson1,Yasuyuki Fujita1, Iain M. Cox2,Clive Wilson2, Noelia Pinal1. 1) MRC Laboratory for MolecularCell Biology and Cell Biology Unit, Department of Anatomyand Developmental Biology, UCL, London, UK. , UniversityCollege London, Gower Street, WC1E 6BT, London, UK; 2)Department of Human Anatomy and Genetics, University ofOxford, South Parks Road, OX1 3QX Oxford, UK.199CLoss of p24 function in Drosophila results in a tissue-specificER stress response and induction of NF-κB-regulated genes.Ginger E. Carney. Department of Biology, Texas A&MUniversity, College Station, TX.200AA widely expressed new isoform of the transport regulatorKlar: ancillary roles in nuclear migration? Sean Cotton, YiGuo, Dae-Hwan Kim, Michael Welte. Rosenstiel Basic MedicalSciences Research Center and Department of Biology,Brandeis University, Waltham, MA.191AThe fruit fly D. melanogaster as a model system for studyingthe role of GADD45 (CG11086) in development. GabriellaShotts, Uri Abdu. Department of Life Sciences, The NationalInstitute for Biotechnology in the Negev, Ben-Gurion University,Beer Sheva, Israel.201BRegulation of Spindle-F protein localization during Drosophilaoogenesis. Dikla Dubin Bar, Uri Abdu. Life Sciences,TheNational Institute for Biotechnology in the Negev,Ben-GurionUniversity, Beer-Sheva, Israel.192BAbl Tyrosine Kinase Activity Regulates Cellular Adhesion andActin Dynamics during Dorsal Closure. Traci L. Stevens1, MarkPeifer2. 1) Biology, Randolph-Macon College, Ashland, VA; 2)Biology, UNC-Chapel Hill, Chapel Hill, NC.202CA novel role of Rab6 in the polarized transport of oskar mRNA.Antoine Guichet1, Jens Januschke1, Emmanuelle Nicolas1,Julien Compagnon1, Bruno Goud2. 1) Institut Jacques Monod,CNRS, Paris, France; 2) Institut Curie, CNRS, Paris, France.193CSecond site noncomplementation screen to identify genesthat interact with Rho. Shannon Stewart, Aaron Welch, RobertWard. Dept Molecular Biosciences, Univ Kansas, Lawrence,KS.203AStudies on the function of APLIP1, the Drosophila JNKinteracting protein-1, in the kinesin-1 mediated axonaltransport. Dai Horiuchi, William M. Saxton. Dept Biol, IndianaUniv, Bloomington, IN 47405.194AAnalysis of activated myosin phosphatase in D. melanogaster.Panagiotis Tsoulos, Frieder Schoeck. Department of Biology,McGill University, Montreal, Quebec, Canada.204BA novel Klar-interacting protein is necessary for correctmovement of lipid droplets in Drosophila embryos. Dae-HwanKim1, Monica Zapata2, Joseph Gindhart2, Michael Welte1. 1)Dept Biol, Brandeis Univ, Waltham, MA; 2) Department ofBiology, University of Richmond, Richmond, VA.195BTyrosine phosphatase Pez antagonizes actin but not RTKsignaling. Kavita Vadali1, Sam Galewsky2, Wubet Mulugeta1,Craig Gatto1, Hyochun Park1, Kevin Edwards1. 1) DeptBiological Sci, Illinois State Univ, Normal, IL; 2) Biology Dept,Millikin Univ, Decatur, IL.196CAPC2 and Diaphanous function together to organize actin inDrosophila syncytial embryos. Rebecca Webb, JasperWeinberg, Mengning Zhou, Brooke McCartney. Dept BiolSci, Carnegie Mellon Univ, Pittsburgh, PA.197ACentrosomin motif 1 is required for recruitment of gammatubulin to centrosomes. Jiuli Zhang, Timothy L. Megraw.Pharmacology and Green Center for Reproductive BiologySciences, The University of Texas Southwestern MedicalCenter, Dallas, TX.198BThe role of Bicaudal D in photoreceptor nuclear positioning.Susan Banks, Martin Kracklauer, Janice Fischer. ICMB,University of Texas at Austin, Austin, TX.205CPotential roles for Drosophila SUN domain proteins in nuclearpositioning. M. Kracklauer, K. Lea, H. Wiora, J. Fischer.Institute for Cell and Molecular Biology, UT, Austin.206AInferno activity is required for early secretion andcellularization in Drosophila embryos. Kate Monzo, HowardWang, John C. Sisson. The Section of MCD Biology and theInstitute for Cellular and Molecular Biology, University of Texas,Austin, TX.207BTrafficking of Fragile X protein and associated mRNAs in neuraldevelopment. Marianna Pinter, Daniela Zarnescu. Molecularand Cellular Biology, University of Arizona, Tucson, AZ.208CRole for Membrane Trafficking in Male Meiotic Cytokinesis.Carmen Robinett1, Rebecca Farkas2, Yukiko Yamashita2,Maria Grazia Giansanti3, Maurizio Gatti3, Margaret Fuller2.1) Dept Biological Sciences, Stanford Univ, Palo Alto, CA,USA; 2) Developmental Biology, Stanford University Schoolof Medicine, Stanford, CA, USA; 3) Dipartmento di Genetica eBiologia Moleculare, Universita di Roma, Rome, Italy.

POSTER SESSIONS41Poster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.209AAdherens Junction Remodeling via Intracellular ProteinTrafficking. Jeremiah F. Roeth1, Mark Peifer1,2. 1) LinebergerComprehensive Cancer Center, University of North Carolina,Chapel Hill, NC; 2) Department of Biology, University of NorthCarolina, Chapel Hill, NC.210BEpithelial Notch localizes to subapical complex and adherensjunctions by polarized exocytosis and Dynamin-dependenttranscytosis. Nobuo Sasaki1, Takeshi Sasamura1, 2, HiroyukiO. Ishikawa3, Maiko Kanai1, 2, Kenji Matsuno1, 2, 3. 1) Dept.Biol.Sci/Tech, Tokyo University of Science, Chiba, Japan; 2)PRESTO, JST; 3) GDRC, Tokyo University of Science, Chiba,Japan.211CKinesin Heavy Chain and Neuronal Polarity. KristinaSchimmelpfeng, Lawrence S. B. Goldstein. Dept Cell & MolecMedicine, Univ California, San Diego, La Jolla, CA.212AEfficient protein trafficking requires trailer hitch, a componentof a ribonucleoprotein complex localized to the ER. JamesWilhelm, Michael Buszczak, Suzanne Sayles. DeptEmbryology, Carnegie Inst Washington, Baltimore, MD.213BMsp-300 and nuclear migration. Xuanhua Xie, Janice Fischer.MCDB, ICMB, UT Austin, Austin, TX 78712.214CRegulation of cytoskeleton remodeling by Rab35. Jun Zhang,Matthew Scott. Departments of Developmental Biology,Genetics, and Bioengineering, Howard Hughes MedicalInstitute, Stanford University School of Medicine, Stanford,CA 94305.215Arab GDI and its interaction with Gint3, a UBX-domaincontaining protein. Erin Kahle, Dan Holtzman, Alexis Moore,Alex Chen, Brian Richardson, Katherine Ayres, NaveenSangji, Michelle Keese, Clarissa Cheney. Biology, PomonaCollege, Claremont, CA 91711.216BMutational analysis of Drosophila rab GDP dissociationinhibitor (GDI) function. David Levine1, Jonathan Lee1, RyanTakeshita1, Helen Minye2, John Merriam2, Clarissa Cheney1.1) Biology, Pomona College, Claremont, CA; 2) Mol. Cell &Devel. Biology, UCLA, Los Angeles CA.217CCharacterization of Dynamin function in membrane traffickingduring early Drosophila embryogenesis. Richa Rikhy, ManosMavrakis, Jennifer Lippincott-Schwartz. CBMB, NICHD, NIH,18T, 101, 18 Library Drive, Bethesda, MD 20892.218ARoles of the lipid kinase, Fab1, in endocytic trafficking andsignaling. Tor E. Rusten1, Lina M. W. Rodahl1, Krupa Patni1,Christos Samakovlis 2 , Andreas Brech 1 , Harald A.Stenmark 1 . 1) Dept Biochemistry, Norwegian RadiumHospital, N-0310 Oslo, Norway; 2) Department ofDevelopmental Biology, Wenner-Gren Institute, StockholmUniversity, S-106 96 Stockholm, Sweden.219BEffects of xenobiotics on dMRP mutants and the dMRP gene.Jolene T. Cogbill1, Steven Robinow2. 1) Cell and MolecularBiology, University of Hawaii, Manoa, Honolulu, HI; 2) Dept ofZoology, University of Hawaii, Manoa, Honolulu, HI.220CEcdysone responsive secretory networks in the larval salivarygland. Benjamin Costantino, Kelly Alexandre, AndrewAndres. University of Nevada, Las Vegas, Department ofBiology, Las Vegas, NV.221AFunctional study on Lasp gene in Drosophila. Soojin Lee1,Norbert Perrimon 2, Frieder Schöck 1. 1) Department ofBiology, McGill University, RM W5-8, 1205 Dr. Penfield ,Montréal, QC, Canada; 2) Harvard Medical School,Department of Genetics, New Research Building/RM 339, 77Av. Louis Pasteur, Boston, MA 02115.222BHeteromerization of innexin gap junction proteins regulatesepithelial tissue organization. Corinna Lehmann1, HildegardLechner1, Birgit Löer1, Martin Knieps2, Sonja Herrmann2,Michael Famulok2, Reinhard Bauer1, Michael Hoch1. 1)Institute for Molecular Physiology and Developmental Biology,Universtiy Bonn, Germany; 2) Kekulé-Institute for OrganicChemistry and Biochemistry, University Bonn, Germany.223CHindsight controls epithelial integrity, cell migration and polarcell fate in the ovary. Mariana Melani, Denise J. Montell. DeptBiological Chemistry, Johns Hopkins University, School ofMedicine, Baltimore, MD.224AAnalysis of a novel mutant with germ band retraction defectsin Drosophila. Amila Sarac1, Norbert Perrimon2, FriederSchöck1. 1) Biology , McGill University, Montreal, Quebec,Canada; 2) Department of Genetics, Howard Hughes MedicalInstitute, Harvard Medical School, Boston, Massachusetts02115, USA.225BGenetic mosaic analysis reveals effects of APC2 APC1 doublemutant clones during Drosophila wing development. SandraG. Zimmerman, Carolyn A. Mallozzi, Lesley M. Holot, BrookeM. McCartney. Dept Biological Sci, Carnegie Mellon Univ,Pittsburgh, PA.

42POSTER SESSIONSPoster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.Genome and Chromosome Structure226CMapping and functional analysis of genes in Drosophilaheterochromatin. Kathleen Fitzpatrick, Donald Sinclair,Monika Syrzycka, Catherine Jackson, Kate Auyeung,Robert Hollebakken, Barry Honda. Dept Biological Sci,Simon Fraser Univ, Burnaby, BC, Canada.235CA Novel Cell Culture Based System for Studying ChromatinBoundary in Drosophila. Mo Li, Vladimir Belozerov, HainiCai. Dept Cellular Biol, Univ Georgia, Athens, GA.236AModifier screen for SF1 boundary activity in Drosophilahomeotic gene complex. Sharmila Roy, Haini Cai. CellularBiology, University of Georgia, Athens, GA.227AGenome-wide Mapping of Histone modifications in Drosophila.Sasha Langley, Gary Karpen. Dept MCB, Univ CaliforniaBerkeley/LBNL, Berkeley, CA.237BGenetic and molecular characterization of Su(z)2. RichardEmmons, Heather Genetti, Stephen Filandrinos, Jill Lokere,Ting Wu. Genetics, Harvard Medical School, Boston, MA.228BMaize paramutation-associated repeats cause heritable genesilencing in Drosophila. Lori McEachern1, Vett Lloyd2. 1)Department of Biology, Dalhousie University, Halifax, NS,Canada; 2) Department of Biology, Mt. Allison University,Sackville, NB, Canada.238CThe ESC and ESC-Like Polycomb group proteins arealternative subunits of a histone methyltransferase complexand are differentially deployed during development. NealJahren 1, Liangjun Wang 2, Marcus L. Vargas 1, Erica F.Andersen1, Richard S. Jones2, Jeffrey A. Simon1. 1) Dept. ofGenetics, Cell Biology and Development, University ofMinnesota, Minneapolis, MN; 2) Department of BiologicalSciences, Southern Methodist University, Dallas, TX.229CDifferential regulation of gene expression and cell cycleprogression by SWI/SNF-class chromatin remodelers. YuriMoshkin, Lisette Mohrmann, Peter Verrijzer. Department ofBiochemistr y, Erasmus Medical Center, Rotterdam,Netherlands.230ACharacterizing the role of the Brm chromatin remodelingcomplex in Wingless signaling. Yunyun Ni, Tim Blauwkamp,Ken Cadigan. Dept MCDB, Univ Michigan, Ann Arbor, MI48105.231BSu(var)3-9 and Heterochromatin Protein 1 regulate nucleolarorganization by inhibiting formation of extrachromosomalrepeated DNAs. Jamy Peng1,2, Gary Karpen1,2. 1) Dept MolCell Biol, UC Berkeley, Berkeley, CA; 2) Life Sciences Division,Lawrence Berkeley National Lab, Berkeley, CA.232CEffects of Histone Misexpression on Chromatin Structure inDrosophila. Harmony R. Salzler1, William F. Marzluff1, 2, 3, 4,Robert J. Duronio1, 2, 3. 1) Curriculum in Genetics and MolecularBiology, UNC-Chapel Hill, Chapel Hill, NC; 2) Dept. of Biology,UNC-Chapel Hill, Chapel Hill, NC; 3) Program in MolecularBiology and Biotechnology, UNC-Chapel Hill, Chapel Hill,NC; 4) Dept. of Biochemistry and Biophysics, UNC-ChapelHill, Chapel Hill, NC.233AChromatin Modulation of the Pro-apoptotic Genomic RegionUnderlies The Transition of Sensitivity to Irradiation InducedCell Death in Drosophila Embryos. Lei Zhou, Yanping Zhang,Gina Chan. MGM/UFSCC, UFL, Gainesville, FL.234BRNAi influences the nuclear organization and activity of thegypsy chromatin insulator. Elissa P. Lei, Victor G. Corces.Department of Biology, The Johns Hopkins University,Baltimore, MD.239AComplex interrelation between histone H3 methylation,Polycomb recruitment and gene silencing. Tatyana G. Kahn,Yuri B. Schwartz, Vincenzo Pirrotta. Mol. Biol. and Biochem.,Rutgers University, Piscataway, NJ.240BPairing-sensitive elements regulate Polycomb responsivenessand enhancer-promoter interactions at the Drosophilaengrailed gene. Judith Kassis, Sarah DeVido, DeborahKwon. LMG/NICHD/NIH, Bethesda, MD.241CCharacterization of protein partners and targets genes ofDSP1. Daniel Locker, Martine Decoville. CBM CNRS, Orleans,France.242ARole of Polycomblike in Polycomb group silencing. Urmi Savla,Judith Benes, Junyu Zhang, Liangjun Wang, Rick Jones.Dept Biological Sci, Southern Methodist Univ, Dallas, TX.243BThe N-Terminus of Drosophila ESC Interacts with Histone H3and Is Required for E(Z)-Mediated Histone MethyltransferaseActivity. Feng Tie, Carl Stratton, Peter Harte. Dept Genetics,Case Western Reserve Univ, Cleveland, OH.244CThe Pearl 2 mutation in D. melanogaster is in one of the two γtubulin genes and genetically interacts with the Brmremodeling complex. Martha Vazquez1, Monica Cooper 2,Mario Zurita1, James Kennison2. 1) Inst. Biotecnologia, Univ.Nacional Autonoma Mexico, Cuernavaca, Mexico; 2) Lab. ofMolecular Genetics, National Institute of Child Health andHuman Development, National Institutes of Health, Bethesda,MD 20892, USA.

POSTER SESSIONS43Poster board number is in bold above the title. See page 7 for presentation schedule. The first author is the presenter. Abstracts begin on page 79.245APolycomb-group repression of the Ubx gene in wing imaginaldiscs. Liangjun Wang, Junyu Zhang, Urmi Savla, JudithBenes, Richard Jones. Biological Sci, Southern MethodistUniv, Dallas, TX.246BLoss of roX RNAs disrupts expression of the X and fourthchromosomes. Xinxian Deng1,2, Victoria Meller1. 1) Dept ofBiological Sciences, Wayne State University, Detroit, MI; 2)Dept of Biology, Tufts University, Medford, MA.247CLocal Spreading of the MSL Dosage Compensation Complexfrom Autosomal roX1 Transgenes. Rick Kelley. Dept Molec/Cell Bio, Baylor Col Medicine, Houston, TX.248AThe role of roX1 noncoding RNA in the Drosophila MaleSpecific Lethal complex. Colleen McDaniel, Rick Kelley. DeptMol & Hum Genetics, Baylor Col Med, Houston, TX.249BThe regulation of H4-Lys16 acetylation by an evolutionarilyconserved domain of roX RNA. Yongkyu Park1, Yool Ie Kang1,Joanna Sypula1, Seung-Won Park1, Mitzi I. Kuroda2. 1) Deptof Cell Biology and Molecular Medicine, UMDNJ, Newark, NJ;2) Dept of Genetics, Harvard Medical School, Boston, MA.250CRole of MSL3 in Dosage Compensation. Tuba Sural1, Mitzi I.Kuroda1,2. 1) Department of Genetics, Harvard Medical School,Boston, MA; 2) HHMI.251AGlobal pattern of H4AcK16 location on the male Xchromosome. Yu Zhang, Vaijayanti Gupta, Brian Oliver.Laboratory of Cellular and Developmental Biology, NationalInstitute of Diabetes and Digestive and Kidney Diseases,National Institutes of Health, Bethesda MD 20892, USA.252BActivity of telomeric retrotransposons may be stimulated byterminal deficiencies in trans . Radmila CapkovaFrydrychova 1, Trevor Archer2, James Mason 1. 1) LMG,NIEHS, RTP, NC; 2) LMC, NIEHS, RTP, NC.253CIs there a telomere-linked stress response in Drosophila?James M. Mason1, Harald Biessmann2, Marika F. Walter2,Tim Bradley3. 1) Lab Molec Genetics, D3-01, NIH/NIEHS, ResTriangle Pk, NC; 2) Developmental Biology Center, Universityof California, Irvine, CA; 3) Dept. of Ecology and EvolutionaryBiology, University of California, Irvine, CA.254AEpigenetic telomere protection by Drosophila DNA damageresponse pathways. Sarah Oikemus 1 , Joana QueirozMachado2, Daniel Savukoski1, Claudio Sunkel2, MichaelBrodsky1. 1) Dept PGF&E, Univ Massachusetts, Worcester,Worcester, MA; 2) Instituto de Biologia Molecular e Celular,Universidade do Porto, Porto, Portugal.255BTerminal Telomeric Region is Euchromatic in D. melanogaster.Sudha Prasad1, Harald Biessmann2, V

William Gilliland, R. Scott Hawley. Stowers Inst, Kansas City, MO. 145C Synaptonemal complex assembly requires the N- and C-terminal domains of the transverse filament protein C(3)G. Jennifer K. Jeffress 1, Lorinda K. Anderson 2, Scott L. Page , R. Scott Hawley 1. 1) Stowers Inst, Kansas City, MO; 2) Colorado State Univ., Fort Collins, CO. 146A