Transcription
Emergency Care for Patientswith von Willebrand DiseaseA n i n s t r u c t i o n al m a nu al fo r M e d i c al P ro fe s s i o n al sAuthors and Editors: Susan C. Zappa RN, Lucie Lacasse RN, Rose Jacobson RN, Sherry Purcell RN and Karen Wulff RNMedical Reviewers: David Lillicrap MD, FRCPC and Marcela Torres MDvon Willebrand Disease (VWD) isclassified by 'type 1, 2, or 3' If thetype is unknown proceed as if type 1,if bleeding continues consult ahematologist.Mucous membranebleeds (pg. 6)Administer therecommendedtreatment andanti-fibrinolyticsGynecological bleeds (pg. 12)Immobilizersp.r.n. for joint bleedsAbdominal bleeds (pg. 10)Trauma (pg. 23)Administer the recommendedtreatmentIce packfor soft tissue, muscle,joint bleedsFor VWD type 3: Avoid intramuscular injections due to thepossibility of causing a musclebleedMinor cuts / bruisesno treatmentHead Injury (pg. 4)Always treatimmediately withthe recommendedtreatment
Treatment and Management Guidelines for von Willebrand DiseaseType of vonWillebrandDiseaseType 1 or Type 2The type 2 VWDknown as ‘pseudoVWD or VWFplatelet type' willonly respondto a platelettransfusion - calla hematologist.Major life-threatening bleeds(ex. - head injury, GI bleeding, severemenorrhagia, etc.)Factor concentrate containing bothFVIII (8) and von Willebrand factor(eg. Humate P ):60-80 Ristocetin cofactor units/kg IVPackage insert will instruct as to rate pervolume.Note: monoclonal or recombinantfactor VIII (8) products do NOT havevon Willebrand factor in them andwill not stop the bleeding.Other bleeds(ex. - sutures, nosebleed, mouth bleed, dentalextractions etc.)Known to respond to desmopressin(DDAVP ):Desmopressin 0.3 mcg/kg IV in 50 ml ofNormal Saline over 30 minutes orsubcutaneously if volume can be givensafely. Recommendation: a maximum doseof 20 mcg.Mucosal bleeding - anti-fibrinolytics (pg. 9)For patients who do not respond to desmopressin:Give a factor concentrate containing bothFVIII (8) and von Willebrand factor(eg. Humate P ):40-60 Ristocetin cofactor units/kg IVPackage insert will instruct as to rate per volume.Note: monoclonal or recombinant factorVIII (8) products do NOT have von Willebrand factor in them and will not stopthe bleeding.Type 3Most severe formof VWD.Factor concentrate containing bothFVIII (8) and von Willebrand factor(eg. Humate P ):60-80 Ristocetin cofactor units/kgFactor concentrate containing bothFVIII (8) and von Willebrand factor(eg. Humate P ):40-60 Ristocetin cofactor units/kgPackage insert will instruct as to rate pervolume.Package insert will instruct as to rate per volume.Note: monoclonal or recombinantfactor VIII (8) products do NOThave von Willebrand factor in themand will not stop the bleeding.Note: monoclonal or recombinant factorVIII (8) products do NOT have von Willebrand factor in them and will not stop thebleeding.Dose ChartIf your institution does not have Humate-P , but does have Alphanate or Koate DVI available,consult a hematologist for guidelines and instructions.Per the Medical and Scientific Advisory Council of the National Hemophilia Foundation:Because of the increased risk of HIV and hepatitis A, B, and C transmission, cryoprecipitate should not be used (for the treatment of von WillebrandDisease) except in an emergency situation where one of the above products is not available and delay of treatment would be life or limb threatening.
BRITISH COLUMBIASaskatchewan Bleeding Disorders ProgramRoyal University HospitalSaskatoon, SKTel: (306) 655-6504After hours: (306) 655-1000MB Bleeding Disorders ProgramHealth Sciences CentreWinnipeg, MBTel: (204) 787-2465Pager: (204) 787-2071 #3346QUÉBECHemophilia ClinicCHUS - Hôpital FleurimontSherbrooke, QCTel: (819) 346-1110 ext. 14560NOVA SCOTIAPediatric Bleeding Disorder ClinicIWK Health CentreHalifax, NSTel: (902) 470-8752 / 470-8819Pager: (902) 470-8888 #1982After hours: (902) 470-8394Hereditary Bleeding DisordersProgram - AdultQE II Health Science CentreHalifax, NSTel: (902) 473-5612NEWFOUNDLANDHemophilia ProgramEastern Health Corporation Health Sciences Centre, Janeway SiteSt. John’s, NLTel: (709) 777-4388After hours Tel: (709) 777-6300LabsX-raysHemophilia ProgramHamilton Health Sciences CorporationMcMaster DivisionHamilton, ONTel: (905) 521-2100 #7597824 hour: (905) 521-2100 ext 76443Southeastern Ontario RegionalInherited Bleeding Disorders ProgramKingston General HospitalDouglas 3Kingston, ONTel: (613) 549-6666 ext. 4683Tel: 24 HR # (613) 548-7850Inherited Bleeding Disorder ClinicSaint John Regional HospitalSaint John, NBTel: (506) 648-7286FactorMedsONTARIOHemophilia Program, Sudbury &North-Eastern OntarioLaurentian Site of HRSRHSudbury, ONTel: (705) 522-2200 ext. 3264South East Regional Health AuthorityHemophilia ClinicMoncton, NBTel: (506) 857-5465 / 857-5467Pager: (506) 558-7158DesmopressinMANITOBARegional Comprehensive Care Centrefor Hemophilia & Hemostasis(Adult Program)Ottawa Hosp. Gen. CampusOttawa, ONTel: (613) 737-8252After hours: (613) 722-7000NEW BRUNSWICKJoint / MuscleSoft TissueSASKATCHEWANHematology ClinicChildren’s Hospital of Eastern OntarioOttawa, ONTel: (613) 737-7600 ext. 2368Regional Hemophilia Centre forEastern QuebecHôpital de l’ Enfant JésusQuébec, QCTel: (418) 649-5624Gyn.Comprehensive Centre for Bleeding DisordersUniversity of Alberta Hospital/Stollery Children’s HospitalEdmonton, ABTel: (780) 407-6588Pager: (780) 445-1683Hemophilia ProgramHospital for Sick ChildrenToronto, ONTel: (416) 813-5871Pager: (416) 377-9716After hours: (416) 813-7500GI / GUSouthern Alberta Hemophilia ProgramAlberta Children’s HospitalCalgary, ABTel: (403) 955-7311After hours: (403) 955-7070Quebec Reference Centre for theStudy of Patients with InhibitorsHem. Clinic - 1er vidéotronSte-Justine HospitalMontréal, QCTel: (514) 345-2360MucousMembr.ALBERTAComprehensive HemophiliaCare CentreSt. Michael’s HospitalToronto, ONTel: (416) 864-5129Pager: (416) 685-9404/9478After hours: (416) 864-5431Hemophilia Clinic - 1er vidéotronSte-Justine HospitalMontréal, QCTel: (514) 345-4931 #6031Pagers: (514) 415-5573 / 415-5584 /415-5807After hours: (514) 345-4788HeadPediatric Hemophilia/ HematologyBC Children’s HospitalVancouver, BCTel: (604) 875-2345 ext. 5335Pager: (604) 875-2161After hours: (604) 875-2161Hemophilia ProgramThunder Bay Regional HospitalScience CentreThunder BayTel: (807) 684 6550Hemophilia ClinicMontreal Children’s HospitalMontréal, QCTel: (514) 412-4420IntroBasicsHemophilia Program of BC (Adult Division)St. Paul’s HospitalVancouver, BCTel: (604) 682-2344, ext. 63026After hours: (604) 682-2344Bleeding Disorders ProgramLondon Health Science Ctr.Victoria HospitalLondon, ONTel: (519) 685-8500 ext. 53582CentersContentHemophilia Treatment Centres - Canada
CentersContentHeadMucousMembr.GI / GUGyn.Joint / MuscleSoft TissueDesmopressinHemophilia Treatment Centers - USAALABAMAARKANSASChildren’s Rehabilitation Services1610 Center St. Suite AMobile, AL 36604Phone: (251) 432-4560Pediatric after hours: (251) 405-5115Arkansas Center for Bleeding DisordersArkansas Children’s Hospital800 MarshallLittle Rock, AR 72202Phone: (501) 364-5961After hours: (501) 364-1100Children’s Rehabilitation ServicesPO Drawer 2328Birmingham, AL 35201-2328Phone: (205) 939-5900Adult after hours: (205) 934-3411Pediatric after hours: (205) 939-9100Children’s Rehab. Services407 Governor’s Dr SW, Ste BHuntsville, AL 35801Phone: (256) 518-8650University of AlabamaBirmingham Medical Center1600 7th Ave S ACC 512Birmingham, AL 35233Phone: (205) 939-9285Adult after hours: (205) 934-3411Pediatric after hours: (205) 939-9100ALASKAAlaska Hemophilia Associationand Treatment Center16958 N. Eagle River LoopEagle River, AK 99577Phone: (907) 622-4045After hours: (907) ONAMountain States RegionalHemophilia Center – TucsonUniv. of AZ H/S Center1501 North Campbell AvenueTucson, AZ 85724Phone: (520) 626-7584After hours: (520) 694-6000Phoenix Children’s HospitalHemophilia CtrO/P Building B1919 E. Thomas RdPhoenix, AZ 85016Phone: (602) 546-0920After hours: (602) 546-0920CALIFORNIAChildren’s Hospital OaklandDiv of Hematology/Oncology747 52nd StreetOakland, CA 94610-4131Phone: (510) 428-3286Children’s Hospital of Central CaliforniaHematology/Oncology9300 Valley Children’s PlaceMadera, CA 93638Phone: (559) 353-5460Pediatric after hours: (559) 353-5460Children’s Hospital of Los AngelesHem/Onc 4650 Sunset Boulevard, Box #54Los Angeles, CA 9002Phone: (323) 669-4141After hours: (323) 660-2450Children’s Hospital of Orange CountyDept of Hem/Oncology455 South Main StreetOrange, CA 92868Phone: (714) 532-8459Adult after hours: (714) 765-6677Pediatric after hours: (714) 765-6677Children’s Hospital, San Diego3020 Children’s WaySan Diego, CA 92123Phone: (858) 966-5811City of Hope National Medical CenterHemophilia Trt Center1500 E. Duarte RdMOB 4 Duarte, CA 91010Phone: (626) 301-8426Orthopaedic Hospital of Los AngelesHemophilia Program2400 S. Flower StreetLos Angeles, CA 90007Phone: (213) 742-1357After hours: (213) 742-1162Stanford University Medical CenterDiv of Hematology/Oncology1000 Welch Road, Suite 300Mail Code 5798Palo Alto, CA 94304Phone: (650) 497-8953University of California at DavisHemophilia Program2360 Stockton Blvd. Ste 1100Davis One BuildingSacramento, CA 95817Phone: (916) 734-3461Adult after hours: (916) 734-2011Pediatric after hours: (916) 734-3591University of California, San Diego200 W. Arbor Drive M/S 0821San Diego, CA 92103Phone: (619) 471-0335Adult after hours: (619) 290-5539University of California, San FranciscoHemophilia Program650 Moffitt, Box 0106San Francisco, CA 94143Phone: (415) 476-1280Adult after hours: (415) 353-2421COLORADOMountain States Regional Hemophiliaand Thrombosis CenterPO Box 6507 MS F416Aurora, CO 80045-0507Phone: (303) 724-0362Adult after hrs: (303) 372-0000Ped. After hours: (303) 861-6740CONNECTICUTUCONN Hemophilia Treatment CenterUniv of Conn Health CenterUniversity Cancer Center263 Farmington Ave.Farmington, CT 06030Phone: (860) 679-2576Adult after hours: (860) 679-2000Yale University School of MedicineYale-New Haven Hemophilia Ctr.Dept. of Ped LMP 4087333 Cedar StreetNew Haven, CT 06510Phone: (203) 785-4640DELAWAREChristiana Care Health ServicesHemophilia Program, L-214Christiana Hospital4755 Ogletown-Stanton Rd.Newark, DE 19718Phone: (302) 733-3542Adult after hours: (302) 737-7700
FLORIDAIdaho Regional Hemophilia CenterMountain States Tumor Inst.Peds. Hem/Onc100 East Idaho StreetBoise, ID 83712-6297Phone: (208) 381-2782After hours: (208) 327-8007INDIANAIndiana Hemophilia andThrombosis Center8402 Harcourt Rd, Suite 420Indianapolis, IN 46260Phone: (317) 871-0000 Ext. 236Adult after hours: (877) 256-8837Pediatric after hours: (317) 871-0000LabsX-raysBackus Children’s Hospital4700 Waters AvenueP.O. Box 23089Savannah, GA 31403-3089Phone: (912) 350-7285Pediatric after hours: (912) 658-3017IDAHOStroger Children’s Hospitalof Cook CountyDept of Ped Hem/Oncology700 S. Wood St., Rm. 7206Chicago, IL 60612Phone: (312) 864-4167Adult after hours: (312) 864-1300Pediatric after hours: (312) 864-1500FactorMedsGEORGIAHemophilia and ThrombosisCenter of HawaiiKapi’olani Med Center forWomen and Children1319 Punahou StreetHonolulu, HI 96826Phone: (808) 983-8551After hours: (808) 524-2575Rush University Medical CenterSection of PediatricHematology/OncologySuite 718 PBI1725 W. Harrison StreetChicago, IL 60612-3833Phone: (312) 942-8114After hours: (800) 847-1674DesmopressinUniversity of South Florida - AdultJames A. Haley V.A. HospitalHematology-111-R13000 Bruce B. Downs BlvdTampa, FL 33612Phone: (813) 972-7582HAWAIINorthwestern UniversityNorthwestern Center forBleeding Disorders676 N. St Clair Suite 850Chicago, IL 60611Phone: (312) 695-6180Adult after hours: (312) 695-0990Joint / MuscleSoft TissueNemours Children’s ClinicDivision of Ped. Hem/Onc807 Children’s WayJacksonville, FL 32207Phone: (904) 390-3789Pediatric after hours: (904) 390-3600Medical College of GeorgiaPediatric Hem. ProgramDept of Pediatric Hem/Onc1446 Harper Street, BG-2013Augusta, GA 30912-3730Phone: (706) 721-3626John H. Stroger, Jr. Hospitalof Cook County - HemophiliaTreatment Centers1900 W. Polk St,Chicago, IL 60612Phone: (312) 864-4167Adult after hours: (312) 864-1300Pediatric after hours: (312) 864-1500Gyn.Miami Comprehensive HemophiliaCenter - PediatricsUniversity of MiamiDept. of Pediatrics (R-131)Miami, FL 33101Phone: (305) 585-5635Pediatric after hours: (305) 585-5400Medical College of Georgia - AdultDept of Adult Hem/Onc1120 15th St BAA-5407Augusta, GA 30912-3125Phone: (706) 721-0870After hours: (706) 721-2505Comprehensive BleedingDisorders Center5019 North Executive DrivePeoria, IL 61614Phone: (309) 692-4533After hours: (309) 636-8998GI / GUAll Children’s HospitalPed Hem/Onc Associates880 6th St So Ste 140St. Petersburg, FL 33701Phone: (727) 767-4176Pediatric after hours: (727) 562-6862Hemophilia of Georgia, Inc.8800 Roswell Road, Ste 170Atlanta, GA 30350Phone: (770) 518-8272Children’s Memorial Hospital2300 Children’s Plaza, Box 30Chicago, IL 60614Phone: (773) 880-3977Pediatric after hours: (773) 880-4000MucousMembr.Georgetown University HospitalLombardi Cancer Center,Division of Hem/Onc3800 Reservoir Road, NWWashington, DC 20007Phone: (202) 687-0117Adult after hours: (202) 687-7243Emory University HemophiliaProgram Office2015 Uppergate Dr. NEAtlanta, GA 30322Phone: (404) 727-1608Adult after hours: (404) 778-5000Pediatric after hours: (404) 778-5000ILLINOISHeadChildren’s National Medical CenterDept of Hem/Oncology111 Michigan Avenue, NWWashington, DC 20010Phone: (202) 884-3622Pediatric after hours: (202) 884-5000Children’s Healthcare ofAtlanta at Scottish RiteAflac Cancer Ctr & BloodDisorders Service5455 Meridian Mark Rd, Ste 400Atlanta, GA 30342Phone: (404) 785-3240After hours: (404) 785-3240IntroBasicsDISTRICT OF COLUMBIACentersContentHemophilia Treatment Centers - USA
CentersContentHeadMucousMembr.GI / GUGyn.Joint / MuscleSoft TissueDesmopressinFactorMedsHemophilia Treatment Centers - USAIOWAMARYLANDUniversity of Iowa Hospitals & ClinicsIowa Reg. Hemophilia CenterDept of Ped 2507 JCPIowa City, IA 52242Phone: (319) 356-4277After hours: (319) 356-1616Johns Hopkins University Medical Center1125 Ross720 Rutland AvenueBaltimore, MD 21205Phone: (304) 614-0834Adult after hours: (410) 955-6070Pediatric after hours: (410) 232-9037KENTUCKYMASSACHUSETTSBrown Cancer CenterHemophilia Treatment Center529 South Jackson Rm 229Louisville, KY 40202Phone: (502) 595-4582Adult after hours: (502) 562-4053Pediatric after hours: (502) 595-4673Boston Hemophilia CenterBrigham and Women’sBrigham & Women’s HospitalBWH Mid Campus- 375 Francis StreetBoston, MA 02115Phone: (617) 732-5844Norton Kosair Children’s Medical Center200 E. Chestnut StreetLouisville, KY 40492Phone: (502) 629-7750After hours: (502) 629-7750Boston Hemophilia CenterChildren’s HospitalFegan 717.2Boston, MA 02115Phone: (617) 355-8246Adult after hours: (617) 732-5656Pediatric after hours: (617) 355-6101University of KentuckyHemophilia Treatment CenterJ457 Kentucky Clinic740 South Limestone StreetLexington, KY 40536-0284Phone: (800) 333-7359After hours: (859) 323-5321LOUISIANAMICHIGANLouisiana Ctr for Bleedingand Clotting DisordersTulane Univ. School of Med.1430 Tulane Av Box TB-31New Orleans, LA 70112Phone: (504) 988-5433After hours: (504) 988-5433LabsX-raysMAINETraumaBibliographyNew England Hemophilia CenterUMass Memorial Hospital119 Belmont StreetWorcester, MA 01605Phone: (800) 955-8252After hours: (800) 955-8252Maine Medical CenterMaine Hemophilia & Thrombosis Center100 US Route 1, Unit 104Scarborough, ME 04074Phone: (207) 885-7683Adult after hours: (207) 885-7683Pediatric after hours: (207) 885-7565Cascade Hemophilia Consortium210 East Huron, Suite C2Ann Arbor, MI 48104Phone: (734) 996-3300Children’s Hospital of MichiganHemostasis &Thrombosis Ctr3901 Beaubien Blvd.Detroit, MI 48201Phone: (313) 745-5690Pediatric after hours: (313) 745-5111DeVos Children’s HospitalDeVos Childrens CoagulationDisorders Program100 Michigan Street, N.E., MC #85Grand Rapids, MI 49503Phone: (616) 391-2033Pediatric after hours: (616) 391-1774DMC Karmanos Cancer InstituteComprehensive Center for BleedingDisorders and Thrombosis4100 John R 4 Hudson WebberDetroit, MI 48201Phone: (313) 576-8707Adult after hours: (313) 745-5111Eastern MichiganHemophilia Treatment CenterHurley Medical CenterOne Hurley PlazaFlint, MI 48503-5993Phone: (800) 257-9432Adult after hours: (810) 762-8200Pediatric after hours: (810) 257-9000Hemophilia Clinic of WestMichigan Cancer Center200 North Park StreetKalamazoo, MI 49007Phone: (269) 373-7479Adult after hours: (269) 373-7488Pediatric after hours: (269) 341-6350Henry Ford HospitalAdult Hemophilia andThrombosis Treatment Center2799 West Grand BoulevardK-13 Hematology / OncologyDetroit, MI 48202-2689Phone: (313) 916-3790Adult after hours: (313) 916-2600Mich. State UniversityCenter for Bleeding Disordersand Clotting Disorders2900 Hannah Blvd Room 202East Lansing, MI 48823Phone: (517) 353-9385Munson Medical Center1105 Sixth StreetTraverse City, MI 49684Phone: (231) 935-7227Adult after hours: (231) 935-5000Pediatric after hours: (800) 468-6766University of Michigan Hemophiliaand Coagulation DisordersF2480 Mott1500 East Medical Center DriveAnn Arbor, MI 48109-0235Phone: (734) 936-6393After hours: (734) 936-6267West Michigan Pediatric at BronsonPed Hematology/Oncology601 John St, Suite E. 300Kalamazoo, MI 49007Phone: (269) 341-6350
Mayo ComprehensiveHemophilia Center200 First St. SW Hilton 106Rochester, MN 55905Phone: (800) 344-7726After hours: (507) 284-2511Mountain States Regional Hemophiliaand Thrombosis CenterPO Box 6507 MS F416Aurora, CO 80045-0507Phone: (303) 724-0362Adult after hrs: (303) 372-0000Ped. After hours: (303) 861-6740MISSOURINEVADAHemophilia TreatmentCenter of Las VegasChildren’s Center forCancer & Blood Diseases3059 S. Maryland Pkwy #202Las Vegas, NV 89109Phone: (702) 732-0971Adult after hours: (702) 732-2011Pediatric after hours: (702) 732-0971Hemophilia Treatment CenterOne Hospital Dr 7W12Columbia, MO 65212Phone: (573) 882-9355After hours: (573) 882-4141NEW JERSEYNewark Beth Israel Medical CenterComprehensive HemophiliaTreatment Center201 Lyons Avenue at Osborne TerraceNewark, NJ 07112Phone: (973) 926-6511Adult after hours: (973) 926-7230Pediatric after hours: (973) 926-7161Hemophilia Center ofWestern New York - Ped.Children’s Hospital of Buffalo219 Bryant St.Buffalo, NY 14222Phone: (716) 878-7446Pediatric after hours: (716) 896-2470Long Island Jewish Medical CenterHemophilia Treatment CenterOncology Institute, Room 358270-05 76th AvenueNew Hyde Park, NY 11040Phone: (718) 470-7380After hours: (718) 343-6776Mary M. GooleyHemophilia Center, Inc.1415 Portland Avenue, Suite 425Rochester, NY 14621Phone: (585) 922-5700After hours: (585) 399-1717LabsX-raysThe John Bouhasin Center forChildren with Bleeding DisordersCardinal Glennon Children’s HospitalSaint Louis Univ. Dept of Pediatrics1465 South Grand Blvd.St. Louis, MO 63104Phone: (314) 577-5332Pediatric after hours: (314) 577-5600Children’s Hospital of PhiladelphiaSpeciality CenterNew Jersey Section of Hem/Onc1012 Laurel Oak Road, Building 1014Voorhees, NJ 08043Phone: (856) 435-7502Pediatric after hours: (215) 590-1000Hemophilia Center ofWestern New York - AdultErie County Medical Center462 Grider Street1st floor, Suite 20Buffalo, NY 14215Phone: (716) 896-2470FactorMedsKansas City Regional Hemophilia CenterThe Children’s Mercy Hospital2401 Gillham RoadKansas City, MO 64108Phone: (816) 234-3508Adult after hours: (816) 404-4000Pediatric after hours: (816) 234-3000Dartmouth-HitchcockHemophilia CenterOne Medical Center DriveLebanon, NH 03756Phone: (603) 650-5522After hours: (603) 650-5000NEW YORKDesmopressinNEW HAMPSHIRETed R. Montoya Hemophilia CenterUniv of N M Dept. of PediatricsMSC10 55901 University of New MexicoAlbuquerque, NM 87121Phone: (505) 272-6420Adult after hours: (505) 272-2111Pediatric after hours: (505) 272-4461Joint / MuscleSoft TissueSaint Louis University Center forBleeding and Thrombotic DisordersHemophilia Treatment Center, Adult ProgramSt. Louis University Hospital, West Pavilion3655 Vista Avenue, 3rd Floor, Hem/OncSt. Louis, MO 63110Office: (314) 577-6168Fax: (314) 268-5643NEW MEXICOGyn.University of MississippiMedical CenterPed Hematology/Oncology350 W Woodrow Wilson DrJackson, MS 39213Phone: (601) 984-2710After hours: (601) 984-1000Nebraska RegionalHemophilia Treatment CenterUniversity of Nebraska Medical Center987680 Nebraska Medical CenterOmaha, NE 68198-7680Phone: (402) 559-4227GI / GUMISSISSIPPINEBRASKAUMDNJ-Robert Wood JohnsonMedical SchoolNew Jersey RegionalHemophilia ProgramOne Robert Wood Johnson Place,Room #378C, CN-19New Brunswick, NJ 08903Phone: (732) 235-6542After hrs: (732) 828-3000Ask for Hem. Fellow on callMucousMembr.University of MinnesotaMedical Center, FairviewHemophilia and Thrombosis CenterMMC 713420 Delaware St., SEMinneapolis, MN 55455Phone: (612) 626-6455Adult after hours: (612) 273-3000Pediatric after hours: (612) 813-5940St. Michael’s Medical CenterNadeene Brunini Comp.Hemophilia Care Center111 Central Ave.Newark, NJ 07102Phone: (973) 877-5340After hours: (973) entHemophilia Treatment Centers - USA
CentersContentHeadMucousMembr.GI / GUGyn.Joint / MuscleSoft TissueDesmopressinFactorMedsLabsX-raysHemophilia Treatment Centers - USAMount Sinai School of MedicineRegional ComprehensiveHemophilia Treatment Center19 East 98th Street, Suite 9DBox 1078 New York, NY 10029Phone: (212) 876-8701After hours: (212) 876-8701Univ. of N. Carolina at Chapel HillSchool of MedicineW1022 Old Clinic BuildingCB # 7016Chapel Hill, NC 27599-7016Phone: (919) 966-4736After hours: (919) 966-4736SUNY Upstate Medical UniversityAdult Programc/o Regional Onc Center750 E. Adams StreetSyracuse, NY 13210Phone: (315) 464-8200Adult after hours: (315) 464-8200Wake Forest UniversitySchool of MedicineBaptist Medical CenterThe Bowman Gray CampusDepartment of PediatricsMedical Center BoulevardWinston-Salem, NC 27157-1081Phone: (336) 716-4324Adult after hours: (336) 713-5440Pediatric after hours: (336) 716-4324SUNY Upstate Medical UniversityPediatric Programc/o Center for Children withCancer & Blood Disorder750 E. Adams St, Rm 5400Syracuse, NY 13210Phone: (315) 464-5294Pediatric after hours: (315) 701-1790The Regional Comp. Hemophilia &von Willebrand Trmt Ctr.at Albany Medical College47 New Scotland Ave A 52Albany, NY 12208Phone: (518) 262-5827 or800-773-7080Adult after hours: (518) 786-7723Pediatric after hours: (518) 262-5513UHSH Blood Disorder CenterUHS Wilson Hospital33-57 Harrison StreetJohnson City, NY 13790Phone: (607) 763-6436After hours: (607) 763-6000Weill Medical College of Cornell UniversityRegional Comprehensive HemophiliaDiagnostic and Treatment Center525 E. 68th St, Room P-695New York, NY 10021Phone: (212) 746-3418Adult after hours: (212) 746-2927Pediatric after hours: (212) 746-3400TraumaBibliographyNORTH CAROLINAEast Carolina UniversityBrody School of MedicinePCMH 288 WestGreenville, NC 27858-4354Phone: (252) 744-4676NORTH DAKOTAMeritCare HospitalDBA Roger Maris Cancer CenterHemophilia & ThrombosisTreatment Center820 Fourth Street NorthFargo, ND 58122Phone: (701) 234-7544Pediatric after hours: (701) 234-6000OHIOChildren’s HospitalMedical Center of AkronHemophilia Treatment CenterOne Perkins SquareAkron, OH 44308-1062Phone: (330) 543-8732Cincinnati Children’s HospitalMedical CenterHemophilia Treatment Center3333 Burnet AvenueCincinnati, OH 45229Phone: (513) 636-4269Pediatric after hours: (513) 636-4200Columbus Children’s HospitalColumbus Hemophilia Treatment Center700 Children’s DriveColumbus, OH 43205Phone: (614) 722-3240Pediatric after hours: (614) 722-3250Dayton Children’s Medical CenterWest Central Ohio HemophiliaTreatment CenterOne Children’s PlazaDayton, OH 45404-1815Phone: (937) 641-5877Adult after hours: (937) 641-3000Pediatric after hours: (937) 641-3000Forum HealthYoungstown Hemophilia CenterRegional Referral Center500 Gypsy Lane, 1st FloorYoungstown, OH 44501Phone: (330) 884-4176Northwest Ohio HemophiliaTreatment CenterThe Toledo HospitalChildren’s Medical Center2150 W. Central AvenueToledo, OH 43606Phone: (419) 291-2210Adult after hours: (419) 473-3200Pediatric after hours: (419) 291-8520Ohio State University Medical CenterHemophilia Treatment CenterM414 Starling Loving Hall320 W. 10th AvenueColumbus, OH 43210Phone: (614) 293-8183Adult after hours: (614) 293-8000UHHS ClevelandUniv Hospitals Health SystemPed Hem Mail Stop 605411100 Euclid AvenueCleveland, OH 44106Phone: (216) 844-3345Adult after hours: (216) 844-8220Pediatric after hours: (216) 844-3345University of CincinnatiMedical CenterHemophilia Treatment Center231 Albert Sabin WayMail Location 562Cincinnati, OH 45267-0562Phone: (513) 584-7639Adult after hours: (513) 584-7661OKLAHOMAOklahoma Center for Bleeding Disorders940 N.E. 13th St, Rm. 3B3308Oklahoma City, OK 73104Phone: (405) 271-3661Adult after hours: (405) 271-4222Pediatric after hours: (405) 271-5437OREGONOregon Hemophilia Treatment CenterOR Health & Science Univ.707 SW Gaines RdPortland, OR 97239-2901Phone: (503) 494-8716After hours: (503) 494-9000
Palmetto Health RichlandHemophilia Center of South Carolina7 Richland Medical Park Rd.Suite 203Columbia, SC 29203-6872Phone: (803) 434-3533After hours: (803) 434-3533Children’s Hospital of PhiladelphiaHemophilia Program34th St. & Civic Center Blvd4th Floor Wood BuildingPhiladelphia, PA 19104Phone: (215) 590-4493Pediatric after hours: (215) 590-1000SOUTH DAKOTATENNESSEEPenn Comprehensive Hemophilia ProgramUniv. of PennsylvaniaMed. Ctr - Presbyterian51 N. 39th St. MAB Ste 106Philadelphia, PA 19104Phone: (215) 662-9960Adult after hours: (215) 662-4000University of Tennessee - MemphisHemophilia Clinic of MemphisUniversity of Tennessee920 Madison Ave Suite 300Memphis, TN 38103-3446Phone: (901) 448-6454After hours: (901) 448-6454TEXASFort Worth Bleeding Disorders ProgramCook Children’s Medical Center901 Seventh Avenue, Suite 220Ft. Worth, TX 76104Phone: (682) 885-4007Pediatric after hours: (682) 885-4000UTAHMountain StatesRegional Hemophilia CenterPrimary Children’s Medical Center100 N. Medical DriveSalt Lake City, UT 84113Phone: (801) 588-3477Adult after hours: (801) 581-2121Pediatric after hours: (801) 588-2000LabsX-raysRhode Island HospitalHemophilia Center of Rhode IslandGeorge ClinicProvidence, RI 02903Phone: (401) 444-8250After hours: (401) 350-9707Texas Children’s Hemophiliaand Thrombophilia Center6701 Fannin Ste. 1420Houston, TX 77030Phone: (832) 822-4242After hours: (832) 824-2099FactorMedsRHODE ISLANDVanderbilt University Medical CenterHemostasis-Thrombosis Clinic2220 Pierce Ave 397 PRBNashville, TN 37232-6310Phone: (615) 936-1765Adult after hours: (615) 936-1803Pediatric after hours: (615) 936-1765South Texas Hemophilia &Thrombophilia Trt. CenterChristus Santa Rosa Children’s Hospital333 N. Santa Rosa, 8th FloorSan Antonio, TX 78207Phone: (210) 704-2187DesmopressinSt. Jude Research Hospital332 N. LauderdaleMemphis, TN 38101-0318Phone: (901) 448-6454Adult after hours: (901) 448-6454Pediatric after hours: (901) 448-6454Joint / MuscleSoft TissueLehigh Valley HospitalHemophilia Treatment Center1240 South Cedar Crest Blvd. Suite 103Allentown, PA 18105-1556Phone: (610) 402-0640Adult after hours: (610) 402-7880North Texas ComprehensiveHemophilia Center-Pediatric ProgramChildren’s Medical Center1935 Motor StreetDallas, TX 75235Phone: (214) 456-2379Pediatric after hours: (214) 456-7000Gyn.Hemophilia Centerof Western Pennsylvania3636 Boulevard of the AlliesPittsburgh, PA 15213Phone: (412) 209-7280Adult after hours: (412) 209-7040East Tennessee ComprehensiveHemophilia CenterUniversity of Tennessee Medical Center4 North West1924 Alcoa HighwayKnoxville, TN 37920-6999Phone: (865) 544-9170After hours: (865) 544-9170North Texas ComprehensiveHemophilia CenterAdult ProgramUniv of TX Southwestern Medical School5323 Harry Hines Blvd.Room NC8.126Dallas, TX 75390-8852Phone: (214) 648-1939After hours-Parkland: (214) 590-8000After hours-UT Southwest: (214) 648-7070GI / GUHemophilia Centerof Central PennsylvaniaThe Milton S. Hershey Med. Center500 University Drive, PO Box 850, H046Hershey, PA 17033Phone: (717) 531-7468Adult after hours: (717) 531-8521South Dakota Centerfor Blood DisordersSioux Valley Children’sSpecialty Clinic1305 West 18th StreetSioux Falls, SD 57117-5039Phone: (605) 333-7171After hours: (605) 333-7188Gulf States Hemophilia andThrombophilia Center6655 Travis, Suite 400Houston, TX 77030Phone: (713) 500-8360After hours: (713) 704-4284Or (713) 536-1152MucousMembr.Cardeza Foundation Hemophilia CenterThomas Jefferson University HospitalGibbon Building, Suite 4225111 S. 11th StreetPhiladelphia, PA 19107Phone: (215) 955-8435Adult after hours: (215) 955-8874Galveston Hemophilia ProgramUniversity of TX Med. BranchAdult Hematology/OncologyRm 4.160 John Sealy AnnexGalveston, TX 77555-0565Phone: (409) 772-1165HeadSOUTH hilia Treatment Centers - USA
CentersContentHeadMucousMembr.GI / GUGyn.Joint / MuscleSoft TissueDesmopressinFactorMedsHemophilia Treatment Centers - USAVERMONTWASHINGTONVermont Regional Hemophilia Center108 Cherry St PO Box 70Burlington, VT 05402Phone: (802) 865-1326Puget Sound Blood Center & ProgramHemophilia Program921 Terry AvenueSeattle, WA 98104-1256Phone: (206) 292-6507After hours: (206) 292-6525VIRGINIAChildren’s Hospital of theKing’s DaughtersBleeding Disorders Centerof Hampton Roads601 Children’s LaneNorfolk, VA 23507Phone: (757) 668-7243Pediatric after hours: (757) 668-7243University of Virginia HospitalBox 800386, Pediatric HematologyCharlottesville, VA 22908Phone: (434) 924-8499Adult after hours: (434) 924-0000Pediatric after hours: (434) 924-0211WEST VIRGINIACharleston Area Medical Centerc/o Cancer Care Center3200 MacConkle Avenue, SECharleston, WV 25304Adult after hours: (877) 541-9446West Virginia University Medical CenterRobert C. Byrd Health Sciences CenterMary Babb Randolph Cancer Center
Children's Hospital of Eastern Ontario Ottawa, ON Tel: (613) 737-7600 ext. 2368 Regional Comprehensive Care Centre for Hemophilia & Hemostasis (Adult Program) Ottawa Hosp. Gen. Campus Ottawa, ON Tel: (613) 737-8252 After hours: (613) 722-7000 Hemophilia Program, Sudbury & North-Eastern Ontario Laurentian Site of HRSRH Sudbury, ON
