Reproductive Sciences Program At University Of Michigan

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Michigan Reproductive Sciences, Grand Rapids, 5/21/2010Reproductive Sciences ProgramAt University of Michigan

Reproductive Sciences at UofM Focuses on research leading to an understanding ofreproductive biology. AiAims tto ddevelopl new didiagnosticti andd ththerapeuticti strategiest t i ffordiseases that result in reproduction failure and diseaseprocesses that have their originspgin reproductiveppprocessesbut that are expressed later in life. Encourages broad,broad multidisciplinary involvement inreproductive sciences. RReproductived ti sciencesiare centralt l tto men’s’ andd women’s’health, fertility, and embryonic stem cell biology.

Existingg Programsg T32 - Training Grant in Reproductive Biologyand Endocrinology (NCE; resubmitted) P01 - “PrenatalPrenatal Programming of ReproductiveHealth and Disease” U10 – Reproductive Medicine Network38 Faculty in 12 Departments in 4 Schools

RSP Expansion / Build-outHires:1) Sue Moenter2) Mike Lehman – Co-Director RSP3) Lique CoolenOffer Being Made:4) Molecular Regulation ofGonadotropes FocusSecond Interviews Pending:5) Male Reproductive Genetics6) HPG-Axis Focus

RSP Expansion / Build-out5 New Hires in Reprod Sciences1) 500K Start-up/position2) 100K/yr salary/position3) 150K/150K/yr ffor 3 yrs –Collaborative PilotProgram4) 12K/yr for 3yrs –Annual Symposium

Reproductive DevelopmentalBiologyBob Denver – Dev Biol, Hormones and Embryonic DevelopmentGary Hammer – Internal Medicine, Gonadal Stem CellsKenta Nabeshima – Cell & Dev Biol, Meiotic Chromatin DynamicsProject #100 Takayama et al.Sue O’Shea – Cell & Dev Biol,, EmbryonicyStem CellsGary Smith – Ob/Gyn, Gamete and Embryo DevelopmentJason Swain – Ob/Gyn, Factors Influencing Embryo DevelopmentMatt Wishart – Ob/Gyn,O /GPhosphatase and GameteGFunctionYukiko Yamashita - Cell & Dev Biol, Centrosome and Stem Cells

Reproductive Endocriology andNeuroendocrinologyJill Becker – Psychology, Sex Differences in Sex and BehaviorJacinta Beehner – Psychology, Sex Hormones and BehaviorLiq e Coolen – Physiology,LiquePh siolog NeNeurobiologyrobiolog of SeSexualal BehaBehavioriorProject #100 Takayama et al.Robert Kennedy – Chemistry, Nanoscale Measures of HormonesRoland Kwok – Ob/Gyn, Transcriptional Co-ActivatorsTheresa Lee – Psychology – Gonadal Steroids and BiorhythmsMike Lehman – Physiology,Physiology GnRH Neurons and the HPG AxisJairam Menon - Ob/Gyn, G-Protein Coupled Receptors

Reproductive Endocriology andNeuroendocrinologyRam Menon – Pediatrics,, Insulin and IGF1 in Pregnancygy and Dev.Sue Moenter – Physiology, GnRH and Hypothalamic InfertilityMartin Myers – Medicine, Leptin, Nutrition, and ReproductionVVasanthath PadmanabhanP dbh – Pediatrics,P di t iFFetalt lOOrigini i off RReproductived tiand Metabolic DisordersAudrey Seasholtz - Biological Chem., Stress and ReproductionBob Thompson – Psychiatry,Psychiatry MolMol. RegReg. of Hypothalamic Functionvan Anders – Psychology, Androgens and Behavior NeuroEndo

Reproductive Genetics andEpigeneticsSally Camper – Human Genetics, Genetics of PituitaryTranscription FactorsDana Dolinoy – Environmental Health Science, EnvironmentalEpigenomicsSundeep Kalantry – Human Genetics, Epigenetic Mechanismof X-inactivationX inactivationDiana Robins – Human Genetics, Androgen Receptor Function

Reproductive MedicineRonald Buckanovish – Internal Med,Med Ovarian AngiogenesisGregory Christman – Ob/Gyn, Uterine LeiomyomasProject #100 Takayama et al.Howard Hu - Environ Health Sci, Metal Toxicants and PregnancyJosephine Kasa-Vubu - Peds, Body Composition and PubertyJohn Meeker - Environ Health Sci, Environ Exposure and ReprodJohn Randolph – Ob/Gyn, Hormones and MenopauseYolanda Smith – Ob/Gyn, Brain Imaging and Reproduction

Reproductive Tract BiologyDave Aronoff – Internal Med, Immunology of Female ReprodTractProject #100 Takayama et al.John DeLancey – Ob/Gyn, Birth and Pelvic Floor DysfunctionCraig Harris – Environ Health Sci, Dev Reprod ToxicologyRita Loch-Caruso - Environ Health Sci, Hox Genes and theUterus

North Campus Research ComplexTotal acreage: 173.5 acresGross Sq Ft: 11.97M97MRes. Lab Sq Ft: 1.3M12

Anita Payne Lectureship and PosterDayOctober 15,15 2010- Towsley CenterCenter, UoM- Abstracts due Sept. 15th- Anita Payne Lecture:Kelly E. MayoDepartment of Biochemistry,gy & Cell BiologygyMolecular BiologyCenter for Reproductive ScienceNorthwestern University

At University of Michigan. . Ai t d l di ti d th ti t t i fAims to develop new diagnostic and therapeutic strategies for diseases that result in reproduction failure and disease . Fetal Origin of Reproductive and M