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GE HealthcareEnter the volumeLightSpeed VCT: the first Volume CT

“Imagination at work” is the inspirationthat drives us – an open license to thinkoutside the box and dream of a betterworld for tomorrow. A world that is aspain and stress free as possible forpatients, while enabling physicians toget to an answer accurately, quicklyand reliably.Now, the innovative technology ofLightSpeed VCT makes this worldpossible, opening the door to newand advanced procedure possibilitiesin non-invasive diagnostic imaging.Dare to dream

Volume CT achieves this technologicalleap forward through a radical platformdesign that enables the clinician, for thefirst time, to utilize volume coverage andthin slice imaging concurrently ratherthan alternately.LightSpeed VCT delivers 40mm ofcoverage per rotation while providing0.35mm microVoxel resolution.This unprecedented marriage of highvolume and high resolution has threemajor clinical rewards: dramaticallyreduced acquisition times, improvedimage quality and new clinicalapplications.Volume CTgeneration

New ClinicalApplicationsLightSpeed VCT takesa leap forward in expandingthe role of CT imagingEnhancedWorkflow PlatformInnovativeTechnologyA balanced system design to delivertechnology without compromiseLightSpeed VCT takes workflow to the nextlevel with Xtream FX, the second generationof Xtream technology platform

Why LightSpeeImage quality5-BeatCardiac ,TripleRuleOut ,StrokeWorkUp breakthroughclinicalapplicationsV-Res true64 channeldetectorwith 40mmcoveragePatient friendlyIsotropic0.35mmresolutionwith isotropicdetector sizeand conjugateray reconPerformix Pro tube,100kW,800mA, forcardiac andlarge patientsFastrotation,down to0.35sec, forshort breathhold, reducedsedation,improvedcomplianceVT PatientTable, 227kgcapacity, 2mscannablerange, 43cmminimumheight

ed VCT?Reduced doseThroughputOptidose ,3D andECG dosemodulation,3 dosereductionbowtiefilters, toensurelowest doseto patient,alwaysXtream FXreconstructionand transferat 16 imagesper secVolara DAS - 30%lowerelectronicnoise to givebetter IQ andlower doseDirectMPRand DirectConnect,protocoldriven andautomated3D workflowUptime FutureFaulttolerantdesign andhighreliability –redundantreconprocessors,disk arraysOpenplatform forevolution, inacquisitionand clinicalapplications

Data subject to change.Marketing Communications GE Medical SystemsSociété en Commandite Simple au capital de 130.854.900 EurosRCS Versailles B 315 013 359A General Electric Company,going to market as GE HealthcareFranceParisFax: 33 (0) 1 30 70 98 55JapanTokyoFax: (81) 3-3223-8524SingaporeFax: (65) 291-7006USAMilwaukeeFax: (1) 262 521 6123For more than 100 years, scientists and industryleaders have relied on General Electric for technology,services and productivity solutions. So no matter whatchallenges your healthcare system faces – you canalways count on GE to help deliver the highest qualityservices and support.For details, please contact your GE Healthcarerepresentative today.GE HealthcareChalfont St.Giles,Buckinghamshire,UKwww.gehealthcare.comGE imagination at work Copyright GE Healthcare – 5260-BE

GE HealthcareFastest routeto diagnosisLightSpeed VCT Clinical Applications

True volumereview

Volume CT is opening doors to newclinical applications, and makingroutine studies even better.In cardiac, trauma, pediatric, neuro,angiography, or pulmonary exams,the ability to hit the parameter trifectaof high speed, sub-millimeter resolutionand wide coverage is critical to imagingsuccess. Demonstrated benefitsinclude freezing of cardiovascularmotion, pure arterial phase imaging,and superior MultiPlanar Reformatsthrough routine high resolutionacquisition.LightSpeed VCT is expanding the roleof CT imaging.tric

5-Beat Cardiac Fully robust and repeatableprocedureTriple RuleOut Chest pain management all in oneThe LightSpeed VCT offers the uniquepossibility to scan in just 5 beats, deliveringcoronary arteries, cavities and myocardiumassessment in pure arterial phase. 5-BeatCardiac minimizes heart rate variability,delivering a diagnostic study for virtuallyevery patient. Delivering a true coverage of40 mm per rotation, a rotation speed of0.35 sec, for an acquisition in a shortbreath-bold, LightSpeed VCT makes cardiacCT a routine examination.The Triple RuleOut acquisition based on ECGgated protocol allows extended anatomicalcoverage for a patient exhibiting acutechest pain in an emergency environment,for evidence of coronary disease, pulmonaryembolism or aortic dissection - the threemost life-threatening causes of chest pain.

Stroke WorkUp24x7 operation mode to ruleout cerebral bleedingWhole Body TraumaThe fastest way to a clinicaldecision for polytrauma patientPediatric ImagingBetter patient comfort anddiagnosis when time is criticalIn many institutions, CT is the only modalitystaffed 24 hours a day and 7 days a weekthat can be commonly used to rule outcerebral bleeding. Volume CT delivers, with40 mm of high resolution per rotation.Combined with the GE CT Brain Perfusionapplication, the user can process dynamicimage data and generate functionalperfusion parameters based on changes inimage absorption over time. Low-doseprotocols also permit procedure repeatsin the follow-up phase.Polytrauma patient management requiresspeed, flexibility and detailed visualization.With high resolution scanning from head totoe in 10 seconds, the LightSpeed VCTdelivers. Automated protocols for scanning,reconstruction, multiplanar reformat anddata transfer give you the images youneed. When time cannot be wasted.With the combination of fast acquisitionspeed, large coverage and high spatialresolution in all acquisition modes, theLightSpeed VCT is especially appropriate forpediatric examinations. Quick and precisetogether with reduced radiation dose, suchnon-invasive techniques can be addressedfor restless patients, improving the likelihoodto complete the exam, with the potential toreduce sedation and pre-medication,specially for the exploration of congenitalmalformations such as transposition ofgreat vessels.Expand the role of

OncologyTumor and organ perfusionVolume CT Perfusion provides results in theevaluation of primary cancer targets,metastasis, therapy follow-up and thefuture developments of new therapycourses, such as new anti-angiogenesisdrugs. The extended coverage of theLightSpeed VCT together with newacquisition protocols makes CT a potentialnew investigation technique for myocardiumperfusion. CT is also a choice of investigationfor lung nodules assessment includinggrowth over time and efficiency of therapy.In addition, CT shows growing impact oncolon cancer and polyps characterizationas non-invasive technique well tolerated bythe patient.CT AngiographyPure arterial phase from Circleof Willis to toesWith no trade-off between speed and highresolution, LightSpeed VCT allows a completeassessment of all vascular segmentsincluding lumen views and vessel wall.Optimized injection protocols combinedwith flexibility in acquisition parametersleads to a large anatomical coverage withinarterial phase and consequently to newlimits in vessel visualization. The combinationof unequalled image quality delivered bythe LightSpeed VCT and color-coded plaquecapability, makes CT Angiography a newstandard in vascular investigation.CT imaging

The most comprehensibleset of clinical tools foryour applicationGE offers an unmatched breadth and depth ofanatomical and disease-focused advanced clinicalapplications, directly on the operator console oron the Advantage Workstation.Volume Viewer provides simultaneousaccess to MPVR, MIP, Volume Renderingand 3D enabling comparison studies(either same study with different rendering, or comparing two or more studies).Lung Analysis for one-click auto segmentation and sizing of lung nodulesfrom vessels and pleural surfaces withthe ability to calculate doubling timesand percent growth for follow-up studies.Advantage CTC, which provides newreading tools that reduce overall readingtimes. Exclusive features such as “virtualdissection” mode speeds identification ofpolyps and other anatomy of interest,and delivers a complete colon andabdominal assessment in a single study.Perfusion to provide qualitative andquantitative information for the assessmentof brain stroke, brain tumor and bodytumor conditions including the liver.It combines the lowest injection rates inthe industry with a wide array of intuitivedecision-making tools.Vessel Analysis for the visualization andquantification of vascular anatomy andstructures. The fast, accurate measurements are valuable for stent placementplanning and follow-up, as well as visualization and characterization of highlytortuous vessels.CardIQ Analysis, a comprehensivecardiac package used to streamlinepostprocessing capabilities in the heartand coronary vessels. With GE's exclusivevessel analysis, phase registration andautomated volume rendering application,coronary arteries and anatomy can bedisplayed accurately within minutes.SmartScore to compute coronary arterycalcification scores for assessing theextent of heart disease with multiplescoring algorithms and a comprehensivepatient report.CardEP enables planning for electrophysiology procedures by providingvisualizations of the coronary chambersand veins, including the left atrium,pulmonary veins and coronary sinus,while reducing processing time.

GE HealthcareThe next bigbreakthroughLightSpeed VCT Technology

Revolution

For decades, GE has been the undisputed leader in Computed Tomography.CT has evolved from step-and-rotateto helical to multi-slice scanners. Andnow, for the first time, the generationof Volume CT has arrived.The consummation of five years ofdevelopment, 75 patents, and morethan 100M investment, theGE LightSpeed VCT is a breakthroughin CT technology. LightSpeed VCT isthe largest R&D effort in GE CT history.aryUltimately, the performance of everyCT scanner begins with its detectorand X-ray tube design. At the heart ofthis technological breakthrough:GE's revolutionary V-Res detectorwith true 64 channel microVoxel acquisition, and the industry's mostpowerful X-ray tube: the Performix Pro.Both concepts were developed byGE's Global Research Center, gatheringover a thousand scientists andengineers representing more thantwenty different nations.Today, the LightSpeed VCT will allowyou to discover the Volume CTgeneration, a true symbol of theinnovative spirit that drives GE'sresearch teams throughout the world.

VolumVolaraTM, GE's newdigital DAS, deliversincreased processingpower for highquality imagesand low doseperformance.V-Res detectorThe Volume CT enablerNever before has a CT scanner deliveredvolume, resolution and speed - simultaneously. Welcome to the generation ofVolume CT, where data is acquiredsub-millimeter, all the time.With the ability to acquire 64 channelsat 0.35mm microVoxel resolutionacross 40mm of anatomy in a 0.35secrotation, GE's V-Res detector is the firstto enable routine clinical Volume CT.The V-Res detector was made possibleby GE exclusive technology innovations:fast and efficient HiLight scintillator,scalable Backlit Diode, high densityinterconnects, and the highlyminiaturized Volara digital DataAcquisition System (DAS).The first CT detector with 64 true acquisitionchannels, the 40 mm-wide V-Res detectoruses 100% of its active area to coveranatomy at the fastest speed - withsub-millimeter resolution.

me CT, the next generVolara A true 64-channel DASPerformix Pro tubeThe power to performComplementing GE’s efficient BacklitDiode technology, the V-Res detector ispowered by the Volara digital DAScapable of acquiring 58,368 channelssimultaneously, for over 143 milliondetector channel readouts per second.Its highly miniaturized integratedcircuitry makes the V-Res detectorscalable to increase coverage androws, while achieving the space,weight, thermal, and mechanicalrequirements to rotate at 0.35 sec.LightSpeed VCT’s Volara digital DASaddresses the main limiting factor ofCT image quality - noise - by reducingelectronic noise 30-40% compared toprevious generations of DAS.Volara delivers Volume CT with ALARAdose (As Low As Reasonably Achievable).Volumetric CT places unprecedenteddemands on tube technology. The abilityto scan routinely at sub-second speedswith 40mm coverage and 0.35mmmicroVoxel resolution requiresexceptional power, throughput andX-ray beam quality.Backed by a powerful 100kW generator,the Performix Pro delivers the highestpeak mA capability of any X-ray tubeon the market - up to 800 mA. Wellabove the typical industry performanceof 440-500 mA, this capability providesthe user with ample power to: Image smaller structures and seegreater detail Examine larger patients successfullywithout making tradeoffs Achieve higher gantry rotation speedsfor routine 0.35 second scanning.The GE Performix Pro X-ray tube meets theunprecedented demands on X-ray sourceswith industry leading image quality, peakpower and total throughput. All at the lowestdose that today's CT users demand.

ration is here todayOptidose Volumetric scans withless dosePatient dose reduction and imagequality are inseparable topics.Improved image quality and doseefficiency allow lower doses to be usedfor scanning. At GE, our goal is toenable clinicians to obtain the maximumimage information for the minimumdose. GE’s OptiDose dose reductionprogram has long enabled LightSpeedto demonstrate proven dose efficiencyleadership in independent studies,thanks to features such as SmartTrackdynamic collimation, Color Coding forKids protocols, 3D automatic dosemodulation, ECG dose modulation, andthe electron collector on the PerformixPro X-ray tube. LightSpeed VCT furtherimproves dose efficiency with a new,exclusive X-ray filtration system tailoredfor small, medium or large patients.Fully 3Dvolume reconstructionLightSpeed VCT utilizes a fully threedimensional volumetric reconstructionalgorithm with GE's unique 3D conjugateray reconstruction. Conjugate rayreconstruction provides z-oversamplingfor isotropic 0.35mm resolution, withoutthe dose penalty of other z-oversampling techniques. And volumetric reconstruction delivers superioroff-isocenter and pitch-independentresolution.zxy3D dose modulation accounts for the body inall three dimensions - personalizing eachscan.ECG dose modulation helps to achieve up to50% dose reduction on most cardiac studies.New service paradigmLightSpeed VCT introduces a breakthrough in the way service is deliveredto CT. A dedicated service design andservice infrastructure is the answerto deliver optimal availability andperformance.Thanks to the unique combination ofthe component redundancy and faulttolerant model used in the aircraftindustry, along with the GE proactiveservices remote infrastructure,LighSpeed VCT delivers the quality andproductivity you expect, even in themost demanding utilization environment.In many cases, a single componentfailure no longer impacts the overallequipment availability.In parallel, people are key to deliverfirst class service. Field engineersselected to provide LightSpeed VCTservice are required to complete morethan 100 hours dedicated training. Inorder to ensure that all engineers haveaccess to the most up-to-date serviceinformation, all the global engineeringand service expertise is stored in oneknowledge database available onlinethrough a remote interface. This interface allows a field engineer to not onlydiagnose failures and get support fromGE remote services, but also orderspare parts and track their delivery.

GE LightSpeed VCT is a breakthrough in CT technology. LightSpeed VCT is the largest R&D effort in GE CT history. Ultimately, the performance of every CT scanner begins with its detector and X-ray tube design. At the heart of this technological breakthrough: GE's revolutionary V-Res detector with true 64 channel microVoxel