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ADP600 Series PolarimetersHIGH PRECISION, MULTI-WAVELENGTH PELTIER TEMPERATURE CONTROLLED MODELSFOR PHARMACEUTICAL, CHEMICAL, FOOD & RESEARCH APPLICATIONS
High Precision to4 decimal placesSingle. Dual. Multiple. We’re on your wavelengths.Available as single, dual and multiple wavelength derivatives not only covering the visible spectrum, the newADP600 Series of temperature controlled digital polarimeters are capable of measuring optical rotation tofour decimal places in the highly sensitive ultra-violet region. This capability makes the instrument particularlysuited for use by scientists wishing to measure chiral compounds and other optically active substances in thechemical, pharmaceutical and food sectors as well as for use in academic research.Stable temperatures for accurate resultsKey FeaturesThe ADP600 Series polarimeters feature XPC Technology Xylem’s patented on-board Peltier temperature control system formeasuring optically active samples at stable temperatures. Xylem’sXPC temperature technology is intelligently applied to the samplechamber of the new polarimeters so that measurement can beaccurately made without the need of an external device such as awaterbath to control sample temperature. High accuracy polarimetersThe ADP600 Series Polarimeters have two preset operatingtemperatures being 20 C and 25 C in accordance with Europeanand United States Pharmacopoeia respectively and other usertemperatures between 20 C and 30 C may be configured via theinstrument user interface.Temeperature control limits are also ableto be set between 0.2 C and 0.5 Cproviding faster stabilisation wherea measurement of lower precisionis required (for example withpharmaceutical applicationswhere Pharmacopoeia stipulates /- 0.5 C).ADP600 Series Polarimetersaccept standard size or speciallow volume leur taper polarimetertubes facilitating measurementacross optical path lengths between 5mmand 200mm with tube diameters from 3mm to 8mmbeing readable. For optimum temperature performance, metalbodied tubes are recommended.Optional lids may be easily fitted to the ADP600 SeriesPolarimeters, facilitating flow applications. Simple Methods system Supports FDA regulation 21 CFR Part 11 US/EP/BP/JP compliant External keyboard support RFID security for user clearance Choice of up to 7 common wavelengths 3 USB ports for connectivity to LIMS/PC Ethernet port for networking
ADP MethodologyOne-touch operation for a myriad of methodsIntegral to operational simplicity is the full color, high definition, touch-screengraphical user interface. A menu structure featuring a METHODS system makesfor one-touch calibration and instrument configuration; especially where thespecific rotation of a number of samples is being analysed over a wide range ofconcentrations, path lengths, temperatures and wavelengths.A “Mean Method” is also available, allowing a number of readings to be takenfrom a production batch with the mean being calculated and recorded once theexperiment has been completed. The Mean Method is ideal for pharmaceuticalapplications where compliance with pharmacopoeia is required.The METHODS system is also very similar to that of the wide ranging RFM900-TSeries of high accuracy Peltier controlled refractometers that are in common usethroughout the flavours, fragrance, chemical and pharmaceutical industries.Common scales include I.S.S (z), Specific Rotation, Concentration (g/cm3), Purity,% Invert sucrose, % change (Inversion A-B) and Specific Rotation (concentration,moisture content, length) Batch MEAN Method for Pharmacopoeia and GLP.Fig 1. ADP Series GUI (Method screen)Compliance to Global StandardsAdditionally the ADP600 Series polarimeters feature a secure “print to PDF” function that may be configuredto operate in secure environments in accordance with FDA regulation 21 CFR Part 11 and importantly, theADP600 Series polarimeters meet all of the requirements, including wavelength directives of British, UnitedStates, European and Japanese Pharmacopoeia.ADP600 Series polarimeters along with RFM900-T Series refractometers, and the ADP450 polarimeter offer thefollowing key benefits for 21 CFR 11. Compliance without an intermediate PC – less data security risk and lower system cost Server synchronised clock to prevent data tampering Electronic signatures including multi-verification (Submitter Reviewer Approver) XML output strings with encryption & MD5 check for easy connection to LIMS/Server Full instrument configuration audit trail Configurable users enforcing unique login & signature credentials as well as strict password controls Multi-reading PHR Method for batch measurement as per GLP/PHR Print to Secure PDF with custom header (customer logo can be input)What is Optical Rotation?When plane-polarised light passes through an optically active substance, the plane of polarisation will rotateby an amount that is specifically related to the product through which it travelled.As many chemical compounds display thischiral characteristic, the measurement of opticalrotation using a polarimeter is commonplacewithin the sugar, food, chemical andpharmaceutical manufacturing industries as aproduction control and quality assurance tool.
PolarimetersAccessories and CalibrationA full range of accessories is available including low volume,standard and flow through sample tubes as well as UKAScertified quartz control plates traceable to ICUMSA and PTBfor verifying instrument performance. Validation documents(IQ/OQ/PQ) are also available.A Modular ApproachIn order to better suit customer needs, ADP600 Seriespolarimeters are now designed around a modular selectionguide. This approach means customers will have everything theyneed for their application without spending excess money onthings that they don’t.Fig 2. Quartz Plates, available in single or multiple box setsSimply.Choose yourChoose yourChoose yourChoose yourPolarimeterXPC TubesXPC AdaptorsWindowsPolarimeter byaccuracy andwavelengthXPC Tubes bylength, diameter,volume, acids,flow, volatilityXPC Adaptor tomatch yourtube typeWindow to matchtube diameter andfor Vis/NIR orUV/Vis PassApplication Specific Polarimeter TubesBellingham Stanley polarimeter tubes are manufactured to high quality standards conforming to ICUMSArecommendations and are compatible with most makes of polarimeter.Tube ends are precision ground with windows made from specially selected low strain glass in order to achievehighest accuracy optical rotation measurement.Special tubes, HCl (hydrochloric acid) tubes, XPC Adaptors and cover glasses for ultra-violet measurement arealso available. Please visit our website for further details.Standard XPC tubesHCl XPC tubesLow volume XPC tubesXPC Adaptors
ADP SpecificactionsCommon SpecificationsWavelengths325, 365, 405, 436, 546, 589 & 633nm (model dependent)Range ( A) 89 (-355 to 355 via Method selection)Resolution ( A)0.0001Accuracy ( A) 0.003 (@546, 589 & 633nm) / 0.005 (@325, 365, 405, 436)Temperature Range15-35 CTemperature ControlXPC Technology (Xylem’s patented Peltier temperature control)Accuracy 0.2 CTemperature CompensationNone, Sugar (ICUMSA), Quartz, User definedOptical Density Range0.0 to 3.0 ODMethodsSpecific Rotation, % Concentration, % Invert Sugar, % Inversion (A-B)Temperature Set Points20 & 25 C (variable between 20-30 C via Method)Reading Time15-60 seconds @ 546/589nm and 20/20 C (instrument/sample)Tube TypesXPC (stainless steel), Low Volume, Flow-through, PEEK (Glass)Tube Length5-200mmTube Diameter3-8mmUser InterfaceHigh Definition 7.4” touch-screen colour displayLight SourceUV/Vis lamp (6V, 2A 1000hrs) and narrow band pass filter(s) with auto-off after 1hr of inactivityInterfaces3 x USB (A), 1 x Ethernet, 1 x RS232Power Supply100-250V , 50-60 Hz. 2A.Optional PC, Standard (S/S)35-90100535-95XPC, Standard (S/S)35-912001035-96Low Volume, Luer, (S/S)35-7450.1Low Volume, Luer, (S/S)35-73100.2Low Volume, Luer, (S/S)35-72250.5Low Volume, Luer, (S/S)35-71501PEEK, Standard (glass)35-12100535-99PEEK, Standard (glass)35-132001035-9635-97UV PassWindowsLID rd(included)PEEK: Polyether ether ketone. (S/S): Stainless steel.Chemical compatibility table for materials used is available.Other accessories and spare parts available: Tube washers, window & endcaps. Standard & Hastelloy temperature sensors. Dot-matrix miniature printer. Mini-keyboard and barcode reader. Interface cables.Not what you’re looking for?We are constantly adding new accessories and spare parts to our range. If a tube size or material type is notshown in this brochure, please take a look at our website for new items or contact us today.
Xylem1) The tissue in plants that brings water upward from the roots;2) a leading global water technology company.Bellingham Stanley is part of Xylem Lab Solutions and a leading provider ofrefractometers and polarimeters.Xylem Analytics’ global brands have been leaders in the laboratory instrumentationmarket for decades, and are relied upon every day across more than 150 countries.Working in true partnership with our clients, we listen, learn and adapt to individualneeds, offering deep application expertise built upon our long history of innovation ininstruments and services. Our solutions for analysis, measurement and monitoring helpenable many of today’s modern laboratories and industrial processes, and provide ourcustomers the trusted and high performing solutions they need to succeed.Xylem Analytics is part of Xylem Inc., a global company focused on solving the world’smost challenging and fundamental water issues. As accurate analysis is crucial to thewater industry, Xylem Analytics taps its diverse product brands for leadership in thatfield and beyond, providing the best laboratory and field monitoring instrumentationacross a wide variety of industries.For more information on how Xylem can help you, go to www.xylem.comBellingham Stanley, a Xylem brand, operates anIntegrated Management System complying withISO 9001:2015, ISO 14001:2015 andISO 45001:2018.Bellingham StanleyXylemLongfield RoadTunbridge WellsKent, TN2 3EYUnited KingdomBellingham Stanley (USA)Xylem1700/1725 Brannum LaneYellow SpringsOH 45387USATel: 44 (0) 1892 500400Tel: 1 (979) 690-1711Email: mail: sales.bs.us@xylem.comBellingham Stanley is a trademark of Xylem Inc. or one of its subsidiaries.Hastelloy is a registered trademark of Haynes International. 2021 Xylem ADP-EN/821
Additionally the ADP600 Series polarimeters feature a secure "print to PDF" function that may be configured to operate in secure environments in accordance with FDA regulation 21 CFR Part 11 and importantly, the ADP600 Series polarimeters meet all of the requirements, including wavelength directives of British, United
