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QCLINICALBIOCHEMISTRYREFERENCE RANGESHANDBOOKEastbourne District General Hospital&Conquest Hospital, HastingsVersion:Ratified by:Date ratified:Name of author and title:Date Written:Name of responsible committee/individual:Date issued:Issue number:Review date:Q-PulsePage 1 of 18Issue 14 V2.2Clinical Biochemistry TeamApril 2020Suzanne Fuggle, Cons Clinical ScientistNovember 2011Jacqueline Munro, Lead BMSApril 202014April 2021BIJ-11 Issue 14 (V2.2)Authorised by: J.Munro
Version Control TableVersionnumber andissue numberV1DateAuthorReason forchangeDescription ofchanges madeNovember2011August 2013BiochemistryClinical TeamPaul EatonNovember2013Paul EatonGeneralUpdatesJanuary 2015Sue FuggleV1.3April 2015Sue FuggleUKASRequirementGeneral updateV1.4March 2017Sue FuggleV1.5July 2017Sue FuggleUpdate –analyserchangeCorrectionsReference rangeschanged to reflectcurrent practiceAdd source ofreference rangesAdd U. MagnesiumRemove U.AmylaseReference rangeschanged to reflectcurrent practiceV1.2V1.6July 2017SueFugglecorrectionsV1.7Aug 2017Sue FugglecorrectionsV1.8Aug 2018Sue FuggleCorrectionsV1.9Dec 2018Sue FuggleViapathchangesV2.0May 2019Sue FuggleUnit/ref rangeupdatesV2.1October 2019Sue FugglePTH sample typeV2.2April 2020Sue FuggleV2.3June 2020Sue FuggleV1.0(BiochemistryIssue 2)2013176V1.1Q-PulsePage 2 of 18Addition ofProcalcitoninCGA changed to BCarbamazepine (CBZ)reference range corrected inserted in rr for alb:crtratio removed forDehydroepiandrosteroneS04Male 17 B ref rangeupdated‘driving’ inserted toalcohol. Unit correction forneonatalcopper.Carbonmomoxodeand non fasting Glucoseadded. Random glucoseupdated Group name andcontact phone numbersCarboxyheamoglobinreference range updatedand reference inserted.Cadmium/Chromiumcorrected. Cobalt addedUpdate of reference rangewhere applicable for thosesamples now referred toViapathLDH/Folate change ofreference range.Ferritin : change of unitsPTH sample type changedfrom serum to plasma.Test and interpretativeguide added.Error in naming rectified.BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Consultation TableThis document has been developed in consultation with the groups and/orindividuals in this tableName of individual orgroupTitleDateJoint Quality and GovernanceGroup2015DEPARTMENT OF CLINICAL CHEMISTRY TESTSKEYSpecimen Type:S – SerumU – UrineBl - Whole Blood (EDTA)P – PlasmaF – FaecesBS – Blood SpotACD/AED: anticonvulsant drug / anti epileptic drugLocation and reference range :Lab - Daily routine testsLab* - BatchesPOCT – Point of Care TestingREF- Referral to other hospitals including usereferral lab’s reference rangeNote turn around time for tests referred to anotherhospital is 4 weeks or less unless specifically stated.GOS – paediatric reference ranges obtained fromGreat Ormond Street Hospital .KIT - reference range obtained from manufacturer’sinstructions for use.H- Pathology Harmony Reference RangeGSTS – Guys and St Thomas’ HospitalN/A - Not applicableNot availableW – All Wales Clinical Biochemistry Audit group.Source 1 – The Prescriber Vol 25, Issue 20, Versionof record online:30 Oct 2014T – Trust policyN – NHS Diabetes prevention programme.TEST NAMEREFERENCE RANGES11 deoxycortisol (S) 7.2 nmol/LSOURCERef17 Alpha Hydroxyprogesterone (S)RefAdult 16 years and older0-5 nmol/L results may be higher in luteal phase(see report)Neonates 0-5 days5 days - 16 yearsPost 250 ug Synacthen stimulation0-3 nmol/L0-4 nmol/LNormal: 10 nmol/L at 30 minsQ-PulsePage 3 of 18BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
17 Beta Oestradiol (S)Post MenopausalFollicularMid-CycleLutealMales 18.4 - 50545 - 854151 - 146282 - 25141 - 1593 methoxytyramine (U) 2.6 umol/24hRef3 methoxytyramine (P)5HIAA (U)0 – 120 pmol/L0 - 42 µmol/24hRefACTH (Pl) 46 ng/L 10 ng/L(9 am)(midnight)RefAlbumin (S)Ageg/LNeonate30 - 45Infant30 - 451-16 yrs30 - 50 15Y35 - 50 2.3 mg/mmolLabAlcohol (S)(Ethanol, C2H5OH)The legal driving limit is 80 mg/100ml. Comaensues at 300-400 mg/100ml. Death may occurat levels over 450 mg/100ml.LabKITAldosterone (Pl)Upright 100 - 800RefAlbumin: creatinine ratio (U)LabKITpmol/Lpmol/Lpmol/Lpmol/pmol/LHHKITSupine 5.4 - 30 pmol/LAldosterone/Renin ratio 80 Conn’s unlikely / 200: Conns’ likely80-200: Conn’s notexcludedAlk Phos Isoenzymes (S)Text reportAlkaline Phosphatase (S)AgeNeonateInfant 15y0.9-2.0 g/LAlpha 1 Antitrypsin (S)RefU/L70 - 38060 - 42530 - 130LabH(M F)HRefWhen Alpha 1 Antitrypsin is 1.2 g/L theRef Lab performs the Phenotypeautomatically.Phenotype Text CommentAlpha Fetoprotein (S)0 – 5.8 KU/LLabKITAlpha galactosidase A (Bl) and (P)4 - 21.9 nmol/hr/mlRefAluminium (P) 0.4 μmol/LRefAlanine Transaminase (ALT) (S)AdultQ-PulsePage 4 of 18F 10 - 35U/LM10 – 50 U/LBIJ-11 Issue 14 (V2.3)Authorised by: J.MunroLabKIT
Amino Acid Chromatography (P)Text reportRefAmino Acid Chromatography (U)Text reportRefAmiodarone (P)Desmethylamiodarone0.5 - 2.0 mg/L0.0 - 2.0 mg/LRefAmmonia (P)Age related reference range μmol/LFM0-1M 0 – 1000 – 10016 Y 0 – 500 - 50Adult 11 – 5116 - 60 μmol/L28 – 100 U/LLabKITSerum concs of Amylobarbitone in therapy areusually below 5mg/LRefAmylase (S)Amylobarbitone (S)Anaesthetic ReactionsTryptase(S)Androstenedione (S)LabKITRef2 - 14 ng/mLCollect samples at 0, 3 and 24 hours after thereactionsex related reference range nmol/LRefAdult females: 1.4 – 14.3Adult males: 1.4 – 9.1Angiotensin Converting Enzyme (ACE) Age-related reference range(S)18-Adult: 8 - 52 IU/LAnti-Mullerian Hormone (AMH) (S)Apolipoprotein E Genotype (EDTA)Age and sex related ranges:Male:5.5 – 103.0Female:up to 3 mths4.2 – 23.2to 12 mths 3.1 – 15.5to 17 yrs2.3 – 44.2to 25 yrs8.7 – 83.6to 30 yrs6.4 – 70.3to 35 yrs4.1 – 58.0to 40 yrs1.1 – 53.5to 45 yrs0.2 – 39.1to 51 yrs0.1 – 39.1LabKITpmol/Lpmol/LText reportNote: Test result takes minimum 2 months toreturn.Normal : 0.13 μmol/LHazardous : 0.60 μmol/LFish, shell-fish and crustacea contain a non-toxicarsenical compound.In suspected chronicexposure sea-food is best excluded from the dietfor at least 15 days prior to sample collection.Normal : 0.13 μmol/LHazardous : 1.30μmol/LRefAspartate transaminase (AST) (S)F 0 – 32LabKITBence Jones Protein (U)Text report: Not normally detectedArsenic (Bl)Arsenic (U)Q-PulsePage 5 of 18M 0 – 40 IU/LBIJ-11 Issue 14 (V2.3)Authorised by: J.MunroRefRefLab*
Beta 2 Microglobulin (S) 2.4 mg/LRefBeta HCG (S)F 0 – 5 IU/LM 0 – 3 IU/LLabKITBicarbonate (HCO3) (S)22 – 29 mmol/LLabKITBile Acids (S)0 – 10 μmol/LLabKITBilirubin (S)0 – 21 μmol/LLabKITBilirubin (U)Text reportLabBiotinidase Activity (P)4 00 - 15.00 nmol/L PABA/ml plasma/minRefBlood GasespHpO2pCO27.36 - 7.4412.0 - 15.0 kPa4.5 - 6.1 kPaPOCTC-Peptide (S)An interpretation of the results will depend on theglucose result and the clinical details provided.For further clarification please contact the lab.RefC-Reactive Protein (CRP) 5 mg/LLabKITCA 15-3 (S)0 - 29 kU/LLabKITCA 19-9 (S)0 - 34 kU/LLabKITCA 125 (S)0 - 35 kU/LLabKITCadmium (Bl)Normal (Smoker): 53 nmol/LNormal (Non-smoker): 27nmol/LHazardous: 180nmol/LRefCalcitonin (P)Male 0 – 11.8ng/LRefCalcium (S)LabHCalcium (U)Agemmol/LNeonate2.0 2.7 (Actual not adjusted)Infant - 16 yrs 2.2 2.7Adult2.2 - 2.62.5- 7.50 mmol/24hCalprotectin (F)0 - 49 ug/g and text commentLabCarbamazepine (S)Proprietary Name - Tegretol(ACD/AED)Carbohydrate Def.-Transferrin4 – 12 mg/LLabH 1.6% and Text commentRefCarboxyhaemoglobin (P- Li Hep)Non smokers up to 3%Smokers up to 15%Q-PulsePage 6 of 18Female 0 – 4.8ng/LLabHMedscape2014BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Individuals with haemolytic anaemia and neonatesmay have a level of up to 5%.Carcino Embryonic Antigen (CEA) (S)0 – 5.0 ug/LSmokers up to 6.5 ug/LLabKITCarotene (S)0.9 – 4.7 μmol/LRefCatecholamines (U)NaradrenalinNmol/24h0 – 3M 0 – 533M – 1Y 0 – 951 – 6Y0 – 1836 – 16Y 0 – 420 16Y0 – 500Clobazam30-300 ug/LRefChloride (U)Chloride (S)N/A95 – 108 mmol/LLabKITCholesterol (S)mmol/LF0 – 5.0Cholinesterase & Dibucaine No. (S)Sensitivity to Scoline (Suxamethonium)Cholinest. ActivityDibucaine No.Fluoride No.R02GenotypePhenotypeChromium (Bl)Adrenalinenmol/24h0 – 230 – 230 – 500 – 570 – 100Dopaminenmol/24h0 – 6460 – 6460 – 14170 – 23800 - 3000RefLabKITM0 – 5.0RefChromogranin A (P)600-1400 IU/L76 - 8356 - 6693 - 98Text reportText report0 – 40 nmol/LHip replacements:repeat in 3/12 if 135 nmol/L(MDA/2010/033)0 – 59 pmol/LChromogranin B (P)0 – 149 pmol/LRefCitrate (U)0.6 - 4.8 mmol/24hRefClobazam (S)Desmethylclobazam0.1 – 0.4 mg/Lnone givenRefClonazepam (S)20 – 70 μg/LRefCobalt (Bl)0 – 10 nmol/LHip replacements:repeat in 3/12 if 120 nmol/L(MDA/2010/033)0 – 4 months 1.4 – 7.2 umol/L4- 6 months 3.9 – 17.3 umol/L7– 12 months 7.9 – 20.5 umol/L 1yr 12 -25 umol/LRefCopper (S)Copper (U)Birth to 3 months 0.08 – 0.23 g/LOlder than 3 months 0.2-0.45 g/L0 – 1.0μmol/24hCortisol (S)137 – 429 nmol/L (9 am)Caeruloplasmin (S)Q-PulsePage 7 of 18RefRefRefRefLabWBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Creatinine (S)Age mol/LLabKIT27 – 7727 – 7714 – 3415 – 3123 – 3725 – 4230 – 4729 – 5639 – 6040 – 68FMAdult45 – 8459 - 104A. Male - 95 - 140 ml/minA. Female - 85 - 125 ml/min01M02M01Y03Y05Y07Y09Y11Y13Y15YCreatinine Clearance (U)Creatine Kinase (S)AdultF25 - 200LabKITM40 - 320LabHCrosslinks NTX (U) for Hydroxyproline Premenopausal women - 5 – 65 nM BCE/mMPost menopausal women - 5 – 131 nM BCE/mMMales – Up to 51 nm BCE/mMCreatinine - μmol/LCryoglobulins (Bl)No significant amount should be detected.LabCyclosporin (S), To King's (EDTA)RefRefCystine (U)No specific reference range available. Referenceranges vary from Hospital to Hospital. Pleasestate transplant hospital. 420 mmol/24hrRef*Desmethylobbazam (S)300 – 3000 ug/LRefDehydroepiandrosterone SO4 (S)sex related reference rangeumol/LAdult MalesAdult FemalesRef2.2-15.20.9-11.5Diazepam (P)Desmethyl Diazepam0 - 1.0 mg/L0 - 1.5 mg/LRefDigoxin (S)0.5 – 1.0μg/LLabHDihydrotestosteroneAge and sex related reference rangeQ-PulsePage 8 of 18nmol/LAge/StageMaleCord blood70 – 1750-14 days 1.8902weeks-6 mths0.14 – 4.1306 mths– Tanner 1 0.1 9.8yrs Tanner 1 1009.8-14.5 Tanner 2 0.1-0.5910.7-15.4 Tanner 3 0.28-1.1411.8-16.3 Tanner 4 0.76-1.7912.8-17.3 Tanner 5 0.83-2.24Female70 – 1700.86 – 3.94 0.1 0.1 1000.170-0.410.24-660.14-0.400.10-0.62 Adult0.86-3.40Post menopausal0-1.270- 0.62BIJ-11 Issue 14 (V2.3)Authorised by: J.MunroRef
Diuretic ScreenText reportRefDothiepin (S)DesmethyldothiepinTotalDrug Screen (S)μg/Lμg/Lμg/L (60-200)Text report.RefDrug Screen (U)Text report.RefElastase (faecal) 200μg/g and Text CommentRefEthosuximide (S)(ACD/AED)40 - 100 mg/LRefRefEthylene Glycol13-150 μg/L30-400 μg/LFerritin (S)FemaleMaleFeacal test for Haemoglobin (FIT) (F)0 – 9 µg/gFolate (S)2.4 – 17.5 μg/LFree T4 (S)12 – 22 pmol/LFree T3 (S)3.1 – 6.8 pmol/LLabKITFSH (S)Post Menopausal 25.8 – 134.8 IU/mLFollicular3.5 – 12.5 IU/mLMid-Cycle4.7 – 21.5 IU/mLLuteal1.7 – 7.7 IU/mLMales1.5 – 12.4 IU/mLLabKITG-1-P Uridyl Transferase (Bl)20.2 – 46.4 μmol/h/g HbRefGalactose-1-Phosphate (Bl)RefGlucose (Fluid)Normal - Non Galactosemic - 0.1 μmol/g/HbUntreated Galactosemic - Up to 10.8 μmol/g/HbPatient on diet when levels dropping and levelsstabilized - 0.1 - 0.57 μmol/g/HbAgeU/LFMAdult0 - 400 - 60The CSF glucose is usually 60-80% of the bloodglucose collected within 15 mins of the lumbarpuncture.CSF glucose CANNOT be interpreted without aconcurrent blood glucose.N/AGlucose (Fasting) (P) 5.5 mmol/LGamma GT (S)Glucose (CSF)Q-PulsePage 9 of 18LabKITLabKITLabAnnalsClin.Biohem.2019,Vol.56(1) 183184LabKITLabKITLabLabKITLabNBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
5.5-6.9 mmol/L Non diabetic hyperglycaemia(NDH) 7.0 mmol/L consistent with diabetes, repeat testin 2 weeks if asymptomatic.Glucose (Random) (P)Gut Hormone (P)GlucagonGastrinVasointestinal PeptideSomatostatinPancreatic polypeptideChromogranin AChromogranin BHbA1c (P)HDLC (S)4.1 – 11.0 mmol/LTRef0 - 50 pmol/L0 - 40 pmol/L0 - 30 pmol/L0 - 150 pmol/L0 - 300pmol/L0 - 59 pmol/L0 - 149 pmol/LNon-diabetic 20 – 42 mmol/molGood control 48 – 59 mmol/molDiabetes 48 mmol/mol1.2 – 3.0 mmol/LDiabetes UKLabJoint BritishSocieties fortheprevention ofCardiovasculardisease. (JBS3)HMBS (Washed RBC & P)20 - 42 nmol uroporphoyrin/mL/red cells/hRefHomocysteine (S)0 - 15μmol/LRefHuman Growth Hormone (S)Random 0.3 ug/L excludes acromegalyRandom 6.7 ug/L excludes GH deficiencyLabKITHydroxyproline (U)See Crosslinks NTXRefIgA (S)See ImmunoglobulinsLabKITIgD (S)Text CommentRefIGF-1 (S)Age and sex related reference rangeRefAgeIGFBP3 (SIgG (S)Range (nmol/L)MaleFemale1 – 5Y1.6 - 30.51.2 – 32.96 – 8Y2.2 – 45.53.1 – 51.99 – 11Y3.0 – 60.16.4 – 71.912 – 15Y6.4 – 68.111.8 – 78.116 – 20Y15.6 – 66.914.3 – 68.921 – 24Y13.8 – 47.713.4 – 46.025 – 39Y10.7 – 37.110.2 – 40.740 – 54Y8.1 – 31.06.7 – 35.5 55Y2.0 – 32.22.2 – 32.0Age and sex related reference ranges exist;please contact laboratorySee ImmunoglobulinsLabKITIgG Albumin Ratio / Oligoclonal Bands Age related reference range(S & CSF)AgeAlb g/LIgG g/LCSFQ-PulsePage 10 of 18RefRefBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
300.170.01731-40 0.180.02141-50 0.200.02451-60 0.240.02761-77 0.240.026IgG - See Immunoglobuins reference rangesIgM (S)Ignore the Albumin reference ranges from theReferral lab and use our albumin reference rangesin its place.See ImmunoglobulinsImmunofixation (S)Text reportLabImmunofixation (U)Text reportLabImmunoglobulins (S)AGEIgG g/L01Y03Y06Y09Y11Y13Y15Y19Y150Y2.32 - 14.114.53 - 9.165.04 - 14.655.72 - 14.746.89 - 15.607.59 - 15.507.16 - 17.115.49 - 15.847.00 - 16.00SERUMIgA g/L0.00 - 0.830.20 - 1.000.27 - 1.950.34 - 3.050.53 - 2.040.58 - 3.580.47 - 2.490.61 - 3.480.70 - 4.00IgM g/LLabKITLabKIT0.00 - 1.450.19 - 1.460.24 - 2.100.31 - 2.080.31 -1.790.35 - 2.390.15 - 1.880.23 - 2.590.40 - 2.30Immunoreactive Trypsin (S)0 - 60 μg/LRefInhibin B (S)Post-menopausal0 - 9.8pg/mlPre-menopausal varies depending on stage ofpregnancy cycle0 - 341 pg/mlAn interpretation of the results will depend on theglucose result and the clinical details provided.For further clarification please contact the lab.RefInsulin (P)RefIron studies (S)IronTransferrinTIBC5.8 – 34.5 μmol/L2.0 – 3.6 g/L45 – 81 μmol/LKetones (U)Text reportLactate (Bl)0.5 – 2.2 mmol/LLamotrigine (S)1 - 15mg/L (anticonvulsant)1 - 5 mg/L (bipolar)RefLaxative Screen (U)Text reportRefLevetiracetim (S)10 – 37 mg/LRefLDH (S)Up to 250 U/LLabKITLead (Bl)Normal : 0 - 0.7 μmol/LChildren 0 - 0.5 µmol/LRefQ-PulsePage 11 of 18LabKITLabPOCTLabKITBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Adults industrial exposure 0 - 1.4 µmol/LThere is a need to reduce occupationalexposure if the blood lead exceeds 2.0 µmol/Land suspension from exposure at 3.0 µmol/L orhigher.Lead ((U)LH (S) 100 nmol/24 hPost MenopausalFollicularMid-CycleLutealMales7.7 - 58.8 IU/mL2.4 - 12.0 IU/mL14.0 - 95.6 IU/mL1.0 - 11.4 IU/mL1.7 - 8.6 IU/mLLipid profile (S)Cholesterol0 – 5.0mmol/LTriglycerides0 – 1.7mmo/LHDL - cholesterol1.2 – 3.0mmol/LCalculated LDL cholesterol1.0 – 3.0mmol/LCalcultaed Non HDL - cholesterol 2.5mmol/LLithium (S)0.4 – 1.0 mmol/LLabKITLabJoint BritishSocieties fortheprevention ofCardiovasculardisease. (JBS3)LabHLipase (S)6 – 51U/LRefLp(a) (S) 300 mg/L – Increased CVD riskRefMacro CK (S)Text reportRefManganese (Bl)Children 1yr/Adults 73 - 210 nmol/LChildren 1yr120 - 325 nmol/lRefMagnesium (S)0.70 - 1.00 mmol/LLabHMagnesium (U)0.65 – 1.05 mmol/24hrRefMercury (U) (Long term exposure orNormal: 5 μmol/mol createxposure to Inorganic MercuryCompounds)Mercury (Bl) (Recent exposure -few days Normal: 5 nmol/Lor exposure to Organic MercuryCompounds e.g. Ethyl or Methyl Mercury)Metadrenaline (P)80 – 510 pmol/LRefRefRefMethanolMicroalb/Creatinine Ratio (U)See Albumin/Creatinine Ratio (U)LabMucopolysaccharides (U)Text reportRefQ-PulsePage 12 of 18BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Neurone Specific Enolase (S)0 – 15.0 μg/LRefNitrazepam (S)50 - 150 μg/LRefNormetadrenaline (P)120 – 1180 pmol/LRefOrganic Acid Studies (U)Text reportRefOsmolality (S)275 – 295 mOsmol/kgLabHOsmolality (U)Normal early morning urine 600 mmol/KgOverdose Screen (S)See paracetamol and salicylateOxalate (U)0 - 460 μmol/24hRefParacetamol (S)Not normally detected.LabParaproteins (S)Text reportLab*Paraproteins (U)Text reportLab*Paraquat (U)Not normally detected.RefParathyroid Hormone (PTH) (P)10 - 65 ng/L but needs to be interpreted withserum calcium (for both EDGH and Conquest)LabKITpH (Bl)7.36 - 7.44Phenobarbitone (S)(ACD/AED)20 - 40 mg/LRefPhenylalanine (Phenylketonuria)34 - 110 μmol/LRefPhenytoin (S)Proprietary Name - Epanutin(ACD/AED)Phosphate (S)5 – 20 mg/LLabHLabKITHPhosphate (24 hour urine output) (U)Agemmol/L01M1.3 - 2.601Y1.3 - 2.416Y0.9 - 1.8150Y0.8 - 1.5Adult0.8 - 1.515 – 15 mmol/24 hrPigments (U)Text report.LabPorphobilinogen (U)0 - 1.5 μmol/mmol creatininePlease note an urgent qualitative assay isavailable in house. Please phone lab if required.RefLabKITQ-PulsePage 13 of 18LabContact lab forreferenceLabPOCTKITLabHBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
RefPorphyrins (F)RBC free protoporphyrin: 0 – 200 nmol/L cellsRBC zinc protoporphyrin: 0 – 800 nmol/L cellsHMBS Activity20 – 42nmol/uroporphyrin/mL red cells/hr 37 C0 – 50 mmol/g faecesPorphyrins (U)0 – 35 nmol/mmol creatinineRefPotassium (S)Random ALA Excretion 0 – 3.8 µmol/mmolcreatinine.Total uroporphoyrin (I III) 24 nmol/LHeptacarboxylate porphyrin 4 nmol/LTotal corpoporphyrin (I III) 115 nmol/LAdult3.5 - 5.3 mmol/LPorphyrins (Bl)RefLabHPrimidone (S)Proprietary Name - Mysoline(ACD/AED)Procalcitonin (S)Less than 13 mg/LRefProcalcitonin 0.10 ug/L - Antibiotics strongly discouragedProcalcitonin 0.10- 0.25 ug/L- Antibiotics discouragedProcalcitonin 0.25-0.50 ug/L- Antibiotics encouragedProcalcitonin 0.50 ug/L - Antibiotics strongly encouragedLabKITProcollagen Peptide Type IIIAge related (ug/L)RefAge0 - 3 years4 - 9 years10 - 16 years17 - 18 yearsProgesterone (S)Proinsulin (S)3.4 – 52.63.4 – 12.12.9 – 24.42.0 – 7.0Adult1.2 – 4.2Follicular phase0.2 - 2.8 nmol/LMid-cycle0.4 - 38.1 nmol/LLuteal phase5.8 - 75.9 nmol/LPost-menopausal 0.2 - 0.4 nmol/LMales 0.2 - 0.5 nmol/LLess than 10 pmol/LLabKITRefProlactin (S)Male: 86 – 324mU/L(EDGH and CONQ)Female: 102 – 496mU/LLabKITProtein (CSF)0.15 - 0.45 g/LLabKITProtein:creatinine ratio (U)0 – 45 mg/mmolLabKITProtein Electrophoresis (S)Text reportLab*Protein-24 hour (U)0.00 – 0.14 g/24hLabKITPSA (S)49Y 0.0059Y 0.0069Y 0.00150Y 0.0010 – 15mg/LQuinineQ-PulsePage 14 of 182.00 ng/mL3.004.005.00LabNice CG 12RefBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
ReninUpright 5.4 - 60 mU/LSupine 5.4 - 30 mU/LRefRheumatoid Factor (S)Aldosterone/Renin ratio 80 Conn’s unlikely / 200: Conns’ likely80-200: Conn’s notexcluded 14 IU/mlSalicylate (S)mg/L. Not normally detected.LabSelenium (S)Adult 0.9 - 1.65 μmol/L 16yr 0.4 - 1.4 umol/LRefSex Hormone Binding Globulin (S)LabKITSodium (S)AgeFMup tp 50yrs 32 - 12818 - 54nmol/L51-150 yrs 27 – 12821 – 77nmolLKappa 3.30 – 19.4 mg/LLambda 5.71 – 26.3 mg/LRatio0.26 – 1.65 (0.37-3.10 in patients ondialysis)133 - 146 mmol/LSodium 24 hour output (U)40 - 220 mmol/24hrLabKITSodium ValproateProprietary Name - Epilim(ACD/AED)Solvent Screen (U) (EDTA)50 - 100 mg/LLabKITText reportRefSquamous Cell Carcinoma (SCC) (S)0 – 150ng/dLIRefSteroid Profile (U)Text report - based on relevant biochemical andclinical information provided.RefStone Analysis (Stone)Weight in mgComposition in %RefSugar Chromatography (F)All sugars 1.0 mmol/Kg faecesRef. interval variable: not usually 1.0 mmol/KgRefSugar Chromatography (U)Text report - Less than 1 month of age up to 3mmol/L lactose or galactose, if receiving highcarbohydrate diet. The sugars must be presentin the diet to be detected i.e., to excludegalactosaemia the infant must be having feedscontaining lactose.Text reportRefSerum free light chains (sFLCs) (S)Sugars (U)Sweat TestSweat ChlorideNormal: 40 mmol/LBorderline: 40 – 60mmol/LFibrocystic: 60mmol/LConductivity TestingNormal:0 - 60 mmol/LBorderline: 60 - 90 mmol/LFibrocystic: 90 mmol/L2.0 - 15 μg/LDepends on referral lab.Tacrolimus (FK506)Q-PulsePage 15 of 18LabKITRefLabHLabLabKITRefBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
TCO2 (S)Renamed as bicarbonateTemazepam (S)Text reportRefTestosterone (S)FM50Y 0.29 - 1.678.6429150Y 0.1 - 1.426.6825.7(for both CONQ and EDGH)10 - 20 mg/LLabKITThiamine (EDTA)(Vitamin B1)66.5 - 200 nmol/LRefThyroglobulin (Tg)(S)0 - 40ug/LRefTheophylline (S)Thyroid Function Tests (S)FT3FT4TSHTPMT (thiopurine methyl transferase(E)LabHLabKITTPO (S)3.1 – 6.8 pmol/L (EDGH and CONQ)12 - 22 pmol/L0.27 - 4.2 mU/L26 – 50 pmol/h/mg Hb normal10 – 25 pmol/h/mg Hb carrier 10pmol/h/mg Hb deficiencyPlus text interpretation and advice0-34 IU/mL (Conquest only)Total Protein (S)60 – 80g/LLabHTransketolase (Red Cell)Red Cell Transketolase- 0.40-1.13 U/G HbTransketolase activation - 27 %RefTriglyceride (Fasting) (S)F0 – 1.7LabKITTroponin T (S)Troponin T should be measured at presentationand 6-9 hours later:Mmmol/L0 – 1.7RefLabKITLabKITBoth levels 14ng/L: MI can be ruledout(unless further chestpain or ECG changes suggest furtherinvestigation is required).TSH (S)TSH Binding Inhibiting IgIf at LEAST ONE Troponon T is 14ng/L orabove AND 20% change: not consistent with an acuteevent20-100% change: significant rise, suggestfurther evaluation todistinguish between other causes and chronicelevation in Troponin T. 100% change (a doubling): consistent withmyocardial necrosis.0.27 – 4.2 uU/L (CONQ and EDGH) 1.0 U/Lnegative1.0 – 1.5 U/L borderline 1.5 U/LpositiveRefUrate (S)F 140 – 360Q-PulsePage 16 of 18LabKITLabHμmol/LBIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
M 200 – 430Urate (U)Urea (S)Results greater than 0.35 umol/L are abovetarget for gout preventionDepends on intakeAge01M01Y16Y150Y0.81.02.52.5Metanephaines (U)0 – 3M3M – 1Y1Y – 3Y3Y – 8Y8Y – 12Y 4Hrs0 – 0.90 – 0.60 – 0.60 – 1.40 – 1.90 – 3.3Metadrelalinenmol/24hrs0 – 0.20 – 0.20 – 0.30 – 0.50 – 0.80 – 1.2RefUrobilin (U)Text reportLabUrobilinogen (U)Text reportLabValproate (S)Proprietary Name – Epilim (ACD/AED)50 - 100 mg/LLabKITVery Long Chain Fatty Acids (VLCFA) /Phytanic (Pl)Text reportRefVitamin A (P)AGE (Years)0–20.49 – 1.43 µmol/L3–50.56 – 1.47 µmol/L6-80.66 – 2.00 µmol/L9 – 110.77 – 2.06 µmol/L12 – 13 0.84 – 2.20 µmol/L14 – 15 0.94 – 2.65 µmol/L16 1.40 – 3.84 µmol/LRefVitamin B12 (S)197 – 771 ng/LLabKITVitamin D (25) (S) 75 – 200 nmol/L Optimal50 – 75 nmol/L Adequate for most people25 – 50 nmol/L Insufficient 25 nmol/L Severely deficient, may beassociated with rickets/osteomalacia.Vitamin D (1,25)Vitamin E (P)55 – 139 pmol/LAGE (Years)0–20.0 – 25.0 µmol/L3–57.0 – 30.1 µmol/L6-810.0 – 34.8 µmol/L9 – 11 13.9 – 32.5 µmol/L12 – 13 10.9 – 34.8 µmol/L14 – 15 13.9 – 32.5 µmol/L16 11.6 – 41.8 µmol/LRefRefWhite Cell EnzymeText reportRefQ-PulsePage 17 of 18LabSource 1BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
Xanthochromia (CSF)Text report – based on National GuidelinesLabZinc (P)11 – 19 µmol/LRefNOTE: Reference ranges are liable to change due to updates in equipment, methods,reagents and change in Referral Labs. Reference ranges are updated on our computersystem as they are received.Please contact us if you need further information on tests or reference ranges.Tel no.: 01323-417400 ext – 3896/ 4647 or 01424 755255 ext 8580 / 8019Q-PulsePage 18 of 18BIJ-11 Issue 14 (V2.3)Authorised by: J.Munro
W – All Wales Clinical Biochemistry Audit group. Source 1 – The Prescriber Vol 25, Issue 20, Version of record online:30 Oct 2014 T – Trust policy N – NHS Diabetes prevention programme. TEST NAME REFERENCE RANGES SOURCE 11 deoxycortisol (S) 7.2 nmol/L Ref 17 Alpha Hydroxypr
