Your 2021 Premium Standard Formulary - OptumRx

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Your 2021 Premium Standard FormularyEffective July 1, 2021For the most current list of covered medications or if you have questions:Call the number on your member ID cardVisit your plan’s website on your member ID card or log on to the OptumRx app to: Find a participating retail pharmacy by ZIP code Look up possible lower-cost medication alternatives Compare medication pricing and options

Understanding your formularyWhat is a formulary?About this formularyA formulary is a list of prescribed medications or otherpharmacy care products, services or supplies chosen fortheir safety, cost, and effectiveness. Medications arelisted by categories or classes and are placed into costlevels known as tiers. It includes both brand and genericprescription medications.When differences between this formulary and yourbenefit plan exist, the benefit plan documents rule. Thisformulary may not be a complete list of medications thatare covered by your plan. Please review your benefit planfor full details.To create the list, OptumRx is guided by the Pharmacy andTherapeutics Committee. This group of doctors, nurses, andpharmacists reviews which medications will be covered, howwell the drugs work, and overall value. They also make surethere are safe and covered options.When does the formulary change? Medications may move to a lower tier at any time. Medications may move to a higher tier when a genericequal becomes available. Medications may move to a higher tier or be excluded fromHow do I use my formulary?coverage on January 1 or July 1 of each year.You and your doctor can use the formulary to help youchoose the most cost-effective prescription medications.This guide tells you if a medication is generic or brand, andif special rules apply. If your medication is not listed here,please visit your plan’s website or call the number on yourmember ID card.If a medication changes tiers, you may have to pay a differentamount for that medication.Why are some medications excludedfrom coverage?What are tiers?A medication may be excluded from coverage under yourpharmacy benefit when it works the same as or is similar toanother prescription or over-the-counter (OTC) medication.Tiers are the different cost levels you pay for a medication.Each tier is assigned a cost, set by your employer orplan sponsor.What if I don’t agree with a decision about anexcluded medication?You, your authorized representative, or your doctor canask for a coverage request by calling the number on yourmember ID card.Medication tipsWhat is the difference between brand-name and generic medications?Generic medications contain the same active ingredients (offer the same effect) as brand-name medications, but theyoften cost less. In some situations, brand-name medications could be lower in cost.What if my doctor writes a brand-name prescription?If your doctor gives you a prescription for a brand-name medication, ask if alower-cost option could be right for you.Over-the-countermedications (OTC)What if I am taking a specialty medication?Talk to your doctor about OTCoptions. Even though OTCmedications may not be coveredby your pharmacy benefit,they may cost less than aprescription medication.Specialty medications are used to treat complex conditions and are generally higherin cost. Please note, not all specialty medications are listed in the formulary. Ourspecialty pharmacy can provide most of your specialty medications along withhelpful programs and services. Call 1-855-427-4682 and ask how you can haveyour prescriptions delivered right to your home or doctor’s office.2

Reading your formularyThe formulary gives you choices so you and your doctor can decide your best course of treatment. In this formulary,brand-name medications are shown in UPPERCASE (for example, CLOBEX). Generic medications are shown in lowercase(for example, clobetasol).Tier informationUsing lower tier or preferred medications can help you lower your out-of-pocket cost. Your plan may have multiple or no tiers.Please note: If you have a high-deductible plan, the tier cost levels will apply once you meet your deductible.Drug TierIncludesHelpful TipsTier 1 Lower-costgenerics andsome brand nameUse Tier 1 drugs for the lowest out-of-pocket costs.Tier 2 Mid-range costpreferred brandnameUse Tier 2 drugs instead of Tier 3 to help reduce yourout-of-pocket costs.Tier 3 Higher-costbrand name andsome genericsMany Tier 3 drugs have lower-cost options in Tier 1 or 2.Ask your doctor if they could work for you.Tier EExcludedMay not be covered or need prior authorization. Lower-cost options areavailable and covered.Drug list informationIn this drug list, some medications are noted with letters next to them to help you see which ones may have coveragerequirements or limits. Your benefit plan decides how these medications may be covered.MAuthorized generic or cobranded productPAPrior Authorization – Your doctor is required to give OptumRx more information to determine coverage.QLQuantity Limit – Medication may be limited to a certain quantity.SPSpecialty Medication – Medication is designated as specialty.STStep Therapy – Must try lower-cost medication(s) before a higher-cost medication can be covered3PTier 3 preferred3

Table of ContentsAnalgesics - Drugs for Pain.6Analgesics - Drugs for Pain and Inflammation. 7Anesthetics.7Anti-Addiction / Substance Abuse Treatment Agents. 7Antibacterials.7Anticoagulants.8Anticonvulsants - Drugs for Seizures. 9Antidementia Agents - Drugs for Alzheimer's Disease and Dementia. 9Antidepressants.9Antiemetics - Drugs for Nausea and Vomiting. 10Antifungals.10Antigout Agents. 11Antimigraine Agents. 11Antineoplastics - Drugs for Cancer.11Antiparasitics. 12Antiparkinson Agents. 12Antiplatelets.12Antipsychotics - Drugs for Mood Disorders. 13Antivirals.13Anxiolytics - Drugs for Anxiety.14Bipolar Agents - Drugs for Mood Disorders.14Blood Products and Modifiers - Drugs for Blood Disorders.14Cardiovascular Agents - Drugs for Heart and Circulation Conditions. 14Central Nervous System Agents - Drugs for Attention Deficit Disorder. 17Central Nervous System Agents - Drugs for Multiple Sclerosis. 17Central Nervous System Agents - Miscellaneous. 18Dental and Oral Agents - Drugs for Mouth and Throat Conditions.18Dermatological Agents - Drugs for Skin Conditions. 18Diabetes - Antidiabetic Agents. 20Diabetes - Glucose Monitoring. 21Diabetes - Glycemic Agents. 22Diabetes - Insulins.22Electrolytes / Minerals / Metals / Vitamins.23Gastrointestinal Agents - Drugs for Acid Reflux and Ulcer.24Gastrointestinal Agents - Drugs for Bowel, Intestine and Stomach Conditions.24Genetic or Enzyme Disorder - Drugs for Replacement, Modification, Treatment. 25Genitourinary Agents - Drugs for Bladder, Genital and Kidney Conditions.25Genitourinary Agents - Drugs for Prostate Conditions. 26Hormonal Agents - Adrenal. 26Hormonal Agents - Men's Health.26Hormonal Agents - Osteoporosis. 27Hormonal Agents - Pituitary. 27Hormonal Agents - Sex Hormones and Birth Control.27Hormonal Agents - Thyroid. 29Immunological Agents - Drugs for Immune System Stimulation or Suppression. 29Inflammatory Bowel Disease Agents.30Metabolic Bone Disease Agents - Drugs for Osteoporosis. 31Metabolic Bone Disease Agents - Other. 31Miscellaneous Therapeutic Agents. 31Ophthalmic Agents - Drugs for Eye Allergy, Infection and Inflammation.31Ophthalmic Agents - Drugs for Glaucoma.324

Ophthalmic Agents - Drugs for Miscellaneous Eye Conditions. 32Otic Agents - Drugs for Ear Conditions. 33Respiratory Tract / Pulmonary Agents - Drugs for Allergies, Cough, Cold.33Respiratory Tract / Pulmonary Agents - Drugs for Asthma and Other Lung Conditions. 33Respiratory Tract / Pulmonary Agents - Drugs for Cystic Fibrosis. 35Respiratory Tract / Pulmonary Agents - Drugs for Pulmonary Hypertension. 35Skeletal Muscle Relaxants - Drugs for Muscle Pain and Spasm. 35Sleep Disorder Agents. 365

Drug NameDrug Tier NotesDrug NameAnalgesics - Drugsfor PainDrug Tier Noteshydrocodoneacetaminophen oraltablet1QLhydromorphone hcl oraltablet1QLHYSINGLA ER2PA; QLLAZANDAEmorphine sulfate(concentrate) oralsolution 100 mg/5ml,20 mg/ml1QLmorphine sulfate er oraltablet extended release1PA; QLQLacetaminophencodeine #21acetaminophencodeine #31QLacetaminophencodeine #41QLacetaminophencodeine oral tablet 30015 mg, 300-60 mg1QLAPADAZEapap-caffdihydrocodeine oralcapsule1QLmorphine sulfate oralsolution1BELBUCA2PA; QLMS TA EREbutalbital-apap-caffeine1OXYCODONE HCL EREMoxycodone hcl oraltablet1QLOXYCODONEACETAMINOPHENORAL TABLET 10-300MG, 2.5-300 MG, 5-300MG3QL1QLPA; QLQLBUTRANSTRANSDERMALPATCH WEEKLY 10MCG/HR, 15 MCG/HR,20 MCG/HR, 5MCG/HRECONZIPEDILAUDID doneacetaminophen oraltablet 10-325 mg, 2.5325 mg, 5-325 mg, 7.5325 tanyl1PA; QLQDOLOEFENTANYL CITRATEBUCCAL l hcl oral tablet50 mg1QLFIORICET/CODEINEETREZIX3QLFor more information regarding the tiers and designations in this drug list, please see the Reading yourformulary section of this booklet.6

Drug NameDrug Tier NotesDrug NameDrug Tier NotesULTRACETENAPRELAN3ULTRAMEnaproxen oral tablet1XTAMPZA ER2ZOHYDRO ERAnalgesics - Drugsfor Pain andInflammationEnaproxen sodium oraltablet1PENNSAIDEQMIIZ ODTERELAFENEARTHROTECERELAFEN DSECAMBIAESPRIXECELEBREXEVIMOVOEcelecoxib oral1QLVOLTARENEDICLOFENAC CAP35MGEMZIPSOREDICLOFENAC PATCH1.3%EEMZORVOLEXAnestheticsdiclofenac sodiumexternal gel 1 %1QLlidocaine external patch1diclofenac sodium oral1lidocaine-prilocaineexternal cream1DUEXISELIDODERMEetodolac oral tablet1EFLECTOREibuprofen oral tablet1ZTLIDOAnti-Addiction /Substance AbuseTreatment AgentsINDOMETHACINORAL CAPSULE 20MG3BUNAVAIL3QL1QLindomethacin oralcapsule 25 mg, 50 mgbuprenorphine rphine hclnaloxone hclEMCHANTIX STARTINGMONTH PAK3QLketorolac tromethamineoral1QLnaltrexone hcl oral1NARCAN2LICARTESUBOXONEEmeloxicam oral tablet12MOBICEZUBSOLVAntibacterialsnabumetone oral1ACTICLATEENALFONEamoxicillin oral capsule1PA; QLSTQLFor more information regarding the tiers and designations in this drug list, please see the Reading yourformulary section of this booklet.7

Drug NameDrug Tier Notesamoxicillin oralsuspensionreconstituted1amoxicillin oral tablet1amoxicillin-potassiumclavulanate lavulanate oral tablet1Drug NameDrug Tier Notesdoxycyclinemonohydrate oralcapsule1doxycyclinemonohydrate oral tablet1levofloxacin oral tablet1metronidazole oraltablet1metronidazole vaginal1minocycline hcl oralcapsule1MINOLIRAEazithromycin oralsuspensionreconstituted1azithromycin oral tablet1mupirocin external1cefdinir11cefuroxime axetil1nitrofurantoinmacrocrystalcephalexin oral capsule11cephalexin temacrocrystals1NUZYRA ORAL3ciprofloxacin hcl oraltablet 250 mg, 500 mg1penicillin v potassiumoral tablet1clarithromycin oraltabletSEYSARA31SILVADENEEclindamycin hcl oral1SOLODYNECLINDESSE3SOLOSEC3DIFICID ORALTABLET3sulfamethoxazoletrimethoprim oral tablet1DORYXETARGADOXEDORYX MPCEXENLETA3doxycycline hyclate oralcapsule1XEPI33doxycycline hyclate oraltablet1XIMINOAnticoagulantsELIQUIS2QLELIQUIS DVT/PESTARTER PACK2QLenoxaparin sodium1SP; QLPRADAXA2QLDOXYCYCLINEHYCLATE ORALTABLET DELAYEDRELEASE 80 MGESTFor more information regarding the tiers and designations in this drug list, please see the Reading yourformulary section of this booklet.8

Drug NameDrug Tier Noteswarfarin sodium oral1XARELTO22XARELTO STARTERPACKAnticonvulsants Drugs for SeizuresDrug NameDrug Tier Noteslamotrigine er1QLlamotrigine oral tablet1QLlevetiracetam oraltablet1NAYZILAM3NEURONTINEONFIEoxcarbazepine oraltablet1OXTELLAR XREQUDEXY OUS3BRIVIACT ORAL3carbamazepine oraltablet1CARBATROLEDEPAKOTEEDEPAKOTE EREDEPAKOTESPRINKLESETEGRETOL-XREDILANTIN INFATABSETOPAMAXEDILANTIN ORALCAPSULE 100 MGETOPAMAX SPRINKLEEtopiramate oral tablet1DILANTIN ORALSUSPENSIONETRILEPTALETROKENDI XR3STdivalproex sodium er1VALTOCO3QLdivalproex sodium oraltablet delayed abapentin oralcapsule11gabapentin oral tablet1KEPPRA ORALEzonisamide oralAntidementia Agents- Drugs forAlzheimer's Diseaseand DementiaKEPPRA XRELAMICTALELAMICTAL ODTELAMICTAL STARTERELAMICTAL XR ORALTABLET EXTENDEDRELEASE 24 HOURESTPA; SPdonepezil hcl oral tablet10 mg, 23 mg1memantine hcl oraltablet 10 mg, 5 mg1NAMZARICAntidepressants2amitriptyline hcl oral1STQLFor more information regarding the tiers and designations in this drug list, please see the Reading yourformulary section of this booklet.9

Drug NameDrug Tier NotesBRISDELLEEbupropion hcl er (sr)1bupropion hcl er (xl)oral tablet extendedrelease 24 hour 150mg, 300 mg1Drug NameQLQLDrug Tier NotesPRISTIQEPROZACEsertraline hcl oral tablet1trazodone hcl oral1TRINTELLIX3venlafaxine hcl1venlafaxine hcl er1VIIBRYD3QLQLBUPROPION HCL ER(XL) ORAL TABLETEXTENDED RELEASE24 HOUR 450 MGEbupropion hcl oral1VIIBRYD STARTERPACK3CELEXAEWELLBUTRIN SREcitalopramhydrobromide oraltablet1WELLBUTRIN XLEECYMBALTAEdesvenlafaxinesuccinate er1ZOLOFTAntiemetics - Drugsfor Nausea andVomitingdoxepin hcl oralcapsule 10 mg, 100mg, 25 mg, 50 mg, 75mgGIMOTIE1meclizine hcl oral tablet1metoclopramide hcloral tablet 10 mg1duloxetine hcl oral1EFFEXOR XREondansetron hcl oraltablet 4 mg, 8 mg1escitalopram oxalateoral tablet1ondansetron odt1fluoxetine hcl oralcapsule11prochlorperazinemaleate oralSANCUSOEfluoxetine hcl oral tablet1scopolamine1fluvoxamine maleate1FORFIVO XLELEXAPROEVARUBI (180 MGDOSE)Antifungalsmirtazapine oral tablet11nortriptyline hcl oralcapsuleciclopirox externalsolution11paroxetine hcl1clotrimazole externalcreamPAXIL CRE1PAXIL ORAL TABLETEclotrimazolebetamethasoneexternal creamMQLQL3ST; QLQLFor more information regarding the tiers and designations in this drug list, please see the Reading yourformulary se

Using lower tier or preferred medications can help you lower your out-of-pocket cost. Your plan may have multiple or no tiers. Please note: If you have a high-deductible plan, the tier cost levels will apply once yo