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Bradley S Karon, MD, PhDInformation Technology Steering CommitteeMemberMayo Clinic Rochester CommitteesAllied Health Professional Academic and Promotions CommitteeMemberOrders and Scheduling CommitteeMemberPriorities of Laboratory Testing CommitteeMemberVice ChairPage 7 of 2201/2006 - 200901/2012 – 12/201809/2006 - Present01/2007 - 12/201401/2009 - 12/2014Presentations ExtramuralNational or InternationalInvitedLean/Six Sigma: Complementary Methods to Improve Laboratory OperationsAACC AudioconferenceRochester, Minnesota06/2005Troponin and BNP: The more we learn, the more questions we haveMML Disease Management Strategies Satellite Broadcast12/2008Billing, charging and reimbursement: Unrelated, irrelevant or obscure?Society for Young Clinical Laboratorians WorkshopChicago, Illinois07/2009Laboratory testing for diabetes: An updateAmerican Society for Clinical Laboratory Science Annual MeetingChicago, Illinois07/2009Did You Know? Phlebotomy case studies revealedMayo Medical Labs AudioconferenceRochester, Minnesota10/2009Update in Diabetes Testing and Glycemic ControlAmerican Society for Clinical Pathology Annual MeetingChicago, Illinois10/2009The New Role of STAT Creatinine TestingRadiometer University WebinarRochester, Minnesota04/2010Patient Safety and Tight Glycemic ControlBioConference Live Online Clinical Diagnostics Conference10/2010The role of the laboratory in early sepsis detectionAACC Webinar: Sepsis and the clinical lab01/2011Creatinine Results at the Point of CareRadiometer University WebinarRochester, Minnesota02/2011Glucose meter accuracy and glycemic control: How good is good enough?AACC Webinar: High-value tests for high-impact diseases series05/2012The impact of whole blood creatinine testing accuracy on screening for medicalimagingRadiometer University WebinarRochester, Minnesota08/2012

Bradley S Karon, MD, PhDPage 8 of 22Whole blood creatinine: Reliable or ruse?Canadian Society for Clinical Chemistry WebinarRochester, Minnesota04/2013Point of care platelet function testing: Ready for prime time?AACC Online Conference: The role of POCT in patient care10/2013Achieving concordance between POCT and central laboratory resultsAACC/Seattle Children's Hospital Lab Management SeriesRochester, Minnesota11/2013Viscoelastic coagulation testingFood and Drug Administration, Office of In Vitro Diagnostics and RadiologicHealth, Division of Immunology and Hematology DevicesSilver Springs, Maryland12/2013Preventing Critical Proficiency Testing FailuresCollege of American Pathologists Annual MeetingChicago, Illinois09/2014Best practices in alternative assessment of performanceCollege of American Pathologists Compliance WebinarRochester, Minnesota11/2014Impact of glucose meter error on efficacy of glycemic control after cardiovascularsurgeryIFCC Point of Care Testing International SymposiumCancun, Mexico11/2015Point of Care Testing Then and Now--A ConversationAACC International Point of Care SymposiumCopenhagen, Denmark09/2016Point of Care Lactate for Sepsis Detection: Reconsidering accuracy, precision andconcordance criteriaAACC International Point of Care SymposiumCopenhagen, Denmark09/2016Glucose meter use in critically ill patients: Why improved meter accuracy maylead to better ICU outcomesNova Biomedical WebinarRochester, Minnesota05/2018Root cause analysis for problem solvingOrtho Lab Leadership Scientific SummitSeoul, South Korea05/2018Understanding and avoiding common quality defectsOrtho Lab Leadership Scientific SummitSeoul, South Korea05/2018The relationship between glucose meter accuracy and glycemic control efficacySouth Carolina Point of Care Network webinarRochester, MN07/2018Disease diagnosis and monitoring for the critically illSession moderator, AACC International Point of Care SymposiumAACC International Point of Care SymposiumWashington, DC09/2018OralMolecular Mechanism of Ca-ATPase Regulation by Cyclopiazonic Acid andHalothane03/1994

Bradley S Karon, MD, PhDPage 9 of 22Biophysical Society MeetingNew Orleans, LouisianaMonitoring glucose concentration in patients on intensive intravenous insulintherapyAmerican Association for Clinical Chemistry MeetingSan Diego, California07/2007Practical Applications for Point of Care Testing Programs: Glucose Control andPatient SafetyAmerican Association for Clinical Chemistry MeetingSan Diego, California07/2007Patient safety and tight glycemic control: How close is close enough?American Association for Clinical Chemistry MeetingWashington, District of Columbia07/2008Tips for inspecting a point of care programAmerican Association for Clinical Chemistry MeetingWashington, District of Columbia07/2008Critical and point of care testing for special populationsAACC International Point of Care MeetingBarcelona, Spain09/2008Effect of different glucose meter error tolerances on dosing errors duringintravenous insulin administrationAACC International Point of Care MeetingBarcelona, Spain09/2008Establishing a formal leadership and management curriculum: One institution'staleAmerican Association for Clinical Chemistry MeetingChicago, Illinois07/2009Impact of measurement technology on risk assessment for neonatalhyperbilirubinemiaAmerican Association for Clinical Chemistry MeetingChicago, Illinois07/2009Patient safety and tight glycemic control: Determining accuracy requirements forglucose metersAmerican Association for Clinical Chemistry MeetingChicago, Illinois07/2009Determining Accuracy Requirements for Glucose MetersAmerican Association for Clinical Chemistry MeetingAnaheim, California07/2010Laboratory Tests for Aspirin and Clopidogrel ResponseAmerican Assocation for Clinical Chemistry MeetingAnaheim, California07/2010Leadership and Conflict Resolution: Styles, strengths and weaknessesAmerican Association for Clinical Chemistry MeetingAnaheim, California07/2010Neonatal Bilirubin: Impact of clinical practice guidelines and differentmeasurement technologiesAmerican Association for Clinical Chemistry MeetingAnaheim, California07/2010Glycemic Control IssuesArnold O. Beckman Conference: Glycemic control in the hospitalSan Diego, California04/2011

Bradley S Karon, MD, PhDPage 10 of 22Investigating and responding to critical proficiency testing failuresClinical Laboratory Management Association (CLMA) national meetingAtlanta, Georgia04/2012Impact of glycemic target on accuracy needs for glucose monitors in the intensivecare unitAmerican Association for Clinical Chemistry MeetingLos Angeles, California07/2012Regulatory and accreditation requirements for waived testing and providerperformed microscopyAmerican Society for Microbiology General MeetingDenver, Colorado05/2013What can simulation models tell us about the impact of glucose meter accuracyon insulin dosing decisions in the hospital?Diabetes Technology Society meetingWashington, District of Columbia05/2013Comparison of viscoelastic to routine coagulation testsAmerican Association for Clinical Chemistry MeetingHouston, Texas07/2013Motivation and conflict resolution: Stories from the trenchesAmerican Association for Clinical Chemistry MeetingHouston, Texas07/2013Regulating and accrediting agency requirements for proficiency testingAmerican Association for Clinical Chemistry MeetingHouston, Texas07/2013Impact of glucose meter accuracy on the efficacy of glycemic control in critically illpatients after cardiovascular surgeryAACC International Point of Care SymposiumSan Diego, California09/2014A health system approach to glucose meter use in the hospitalAmerican Association for Clinical Chemistry MeetingAtlanta, Georgia07/2015Preventing critical proficiency testing failuresAmerican Association for Clinical Chemistry MeetingAtlanta, Georgia07/2015Best Practices in Laboratory ComplianceCollege of American Pathologists Annual MeetingNashville10/2015Preventing critical proficiency testing failuresAmerican Association for Clinical Chemistry MeetingPhiladelphia, Pennsylvania07/31/2016Trends in allied health educationAmerican Association for Clinical Chemistry MeetingPhiladelphia, Pennsylvania08/03/2016RegionalInvitedWho Pays for Clinical Pathology?Invited lecture, Washington UniversitySt. Louis, Missouri03/2002

Bradley S Karon, MD, PhDPage 11 of 22CAP Inspector Training SeminarRegional Inspector Training SeminarLas Vegas, Nevada10/2004Evaluation of Three Rapid HIV TestsNorth Country Point of Care NetworkRochester, Minnesota10/2005Hot Topics in PhlebotomyMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota03/2006CAP Inspector and Team Leader Training SeminarsCAP Team Leader Workshop and Inspector Training SeminarMinneapolis, Minnesota04/2006CAP Inspector Training SeminarRegional Inspector Training SeminarMadison, Wisconsin03/2007Trends in Occupational ExposureMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota03/2007QC Theory and PracticeMayo Medical Labs Visiting Faculty Lecture Olmsted Medical CenterRochester, Minnesota12/2007Phlebotomy Top GunMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota03/2008Stump the Chump: PhlebotomyMayo Medical Labs Visiting Faculty LectureMankato, Minnesota04/2008Factors influencing the relationship between transcutaneous and serum bilirubinASCLS-MN Central Area Fall meetingSt. Cloud, Minnesota10/2008Phlebotomy Top GunMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota03/2009Adventures in Specimen Collection: An interactive journeyClinical Laboratory CollaborativeRochester, Minnesota05/2009Quality Control: From theory to practical applicationMayo Medical Labs Visiting Faculty Lecture Winneshiek Medical CenterDecorah, Iowa10/2009Risk Assessment for Neonatal HyperbilirubinemiaClinical Chemistry Grand Rounds U.T. Southwestern Medical CenterDallas, Texas12/2009Monitoring Glucose Concentration in Patients on Intensive Intravenous InsulinTherapyCentral Michigan Association of Medical TechnologistsMount Pleasant, Michigan03/2010Phlebotomy Top GunMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota03/2010

Bradley S Karon, MD, PhDPage 12 of 22Transcutaneous Bilirubin: Pearls, Pitfalls and PossibilitiesTriMark Point of Care Testing 3: Breakthroughs in Patient Care and DataManagementSan Diego, California05/2010Glucose Meter Use in the ICU: How close is close enough?Teleconference Network of Texas Webinar06/2010Phlebotomy Practice in the ICU: Past, present and futureCritical Care Grand RoundsRochester, Minnesota01/2011Transcutaneous Bilirubin: How does it compare to the lab?Southwest Florida Point of Care NetworkRochester, Minnesota02/2011Hot Topics in PhlebotomyMayo Medical Labs Phlebotomy ConferenceRochester, Minnesota10/2011Glucose meters in various settingsBay Area Point of Care Coordinators WebinarRochester, Minnesota12/2011Point of care lactate in the detection of sepsisTeleconference Network of Texas WebinarRochester, Minnesota05/2012Rapid HIV assaysBay State Point of Care Collaborative Web MeetingRochester, Minnesota06/2012Medical complications of phlebotomyMayo Medical Laboratories Phlebotomy ForumRochester, Minnesota08/2012Point of care INR device evaluationVirginia Point of Care Network WebinarRochester, Minnesota08/2012Blood Culture UpdateMayo Medical Laboratories Phlebotomy ForumRochester, Minnesota05/2013Glucose meters for hospital useNorth Texas Point of Care Network WebinarRochester, Minnesota08/2013Efficacy of transcutaneous bilirubin screeningBayChem 2013 (AACC): Emerging concepts in point of care testingSan Leandro, California09/2013Getting to the right discharge numberUtilization Management 2013: Mayo Medical Labs ConferenceAtlanta, Georgia10/2013Phlebotomy Top Gun 2013Mayo Medical Labs Phlebotomy ConferenceRochester, Minnesota10/2013Preventing critical proficiency testing failuresNorth Country Point of Care Testing NetworkMinneapolis, Minnesota10/2013

Bradley S Karon, MD, PhDPage 13 of 22Inpatient laboratory utilizationGME Core Competency Conference Kansas University Medical CenterKansas City, Kansas01/2014Transcutaneous BilirubinNorth Texas Point of Care Network WebinarRochester, Minnesota02/2014Laboratory Test UtilizationMidMichigan Medical Center (Midland) Grand RoundsMidland, Michigan08/2014Laboratory test utilization: Practical solutions across laboratory medicineUtilization Management 2014: Mayo Medical Laboratories ConferenceRochester, Minnesota09/2014Glucose Meter use in the ICU: How close is close enough?North Country Point of Care Network Annual MeetingSt Paul, Minnesota10/2014Point of Care Lactate in the Detection of SepsisNorth Country Point of Care Network Annual MeetingSt Paul, Minnesota10/2014Laboratory test utilizationAACC Southeast Section TeleconferenceRochester, Minnesota12/2014Phlebotomy Top Gun 2015Mayo Medical Labs Phlebotomy ConferenceRochester, Minnesota04/2015Platelet function testing for detecting effects of antiplatelet agentsMinnesota Clinical Laboratory CollaborativeRochester, Minnesota04/2015Utilization management: Inpatient test utilizationIowa CLMA Spring Meeting05/2015Glucose Meters in Acute CareMinnesota Clinical Laboratory CollaborativeBrooklyn Center, Minnesota04/2016Glucose meter testing in critical careNorth Country Point of Care Testing NetworkMankato, MN10/2016Platelet function tests for monitoring antiplatelet agent therapyPoint-of-care Arizona webinarRochester, Minnesota02/2017You want to stick me where? Risks of arterial puncture compared to venipunctureMayo Medical Laboratories Phlebotomy Forum WebinarRochester, Minnesota03/2017Demonstrating the effect of pre-analytical errorsMayo Medical Laboratories Phlebotomy ConferenceRochester, MN04/2017Point of care coagulation testingMayo Medical Laboratories Bleeding and Thrombosing Diseases ConferenceRochester, MN09/2017Platelet function tests for monitoring antiplatelet agent therapyNorth Country Point of Care Network10/2017

Bradley S Karon, MD, PhDPage 14 of 22OralUpdate in Clinical ChemistryASCP Workshop for Laboratory ProfessionalsBaltimore, Maryland03/2008Update in Clinical ChemistryASCP Workshop for Laboratory ProfessionalsEast Hanover, New Jersey05/2009Research Grants AwardedCompleted GrantsIndustryProgramDirector /PrincipalInvestigatorImmature granulocyte (IG) counts as a predictor of severe sepsis andseptic shock. Funded by Sysmex America07/2012 - 12/2013Co-Investigator Utility of Accuvein device for visibility of veins during Venipuncture and 08/2008 - 07/2009Sclerotherapy / Ambulatory phlebectomy: MCHS - Utility of Accuveindevice for visibility of veins during Venipuncture and Sclerotherapy /Ambulatory phlebectomy. Funded by Accuvein, LLCMayo ClinicPrincipalInvestigatorSpectroscopic evaluation of Band 3 on Red Blood Cell membranes inHereditary Spherocytosis. Funded by Small Grants Program-LabMedicine and Pathology11/2005 - 11/2006PrincipalInvestigatorEvaluation of a transcutaneous bilirubin measurement system for usein preventing severe bilirubin toxicity in full-term newborns. Funded byMayo Clinic Clinical Practice Innovation (CPI-10) Program03/2006 - 03/2007ProgramDirector /PrincipalInvestigatorDefining limitations of transcutaneous bilirubin measurement. Fundedby SGP - Small Grants Program 10K11/2011 - 11/2013ProgramDirector /PrincipalInvestigatorCapillary lipid screening in children ages 9-11 years. Funded by SGP - 05/2013 - 05/2015Small Grants Program 10KPrincipalInvestigatorEstimating reference change values for tests of platelet function.Funded by Mayo Clinic01/2015 - 12/2015Co-Investigator Evaluation of a transcutaneous bilirubin monitor in the outpatientsetting. Funded by Scholarly Opportunity Award10/2008 - 09/2010Co-Investigator Preliminary study of cytokine production and red cell membrane05/2009 - 05/2010changes during blood bank storage: Preliminary study of cytokineproduction and red cell membrane changes during blood bank storage.Funded by SGP - Small Grants Program 10KCo-Investigator Effects of Propofol on Intraoperative PTH monitoring duringparathyroidectomy. Funded by SGP - Small Grants Program 10K01/2010 - 01/2011Co-Investigator Point-of-Care Glucose Meter Accuracy in the Operating Room. Funded 04/2014 - 04/2016by SGP - Small Grants Program 10KCo-Investigator Interprofessional Education to Practice: An Application of theInterprofessional Core Competencies. Funded by Endowment forEducation Research Award (EERA)01/2016 - 12/2016

Bradley S Karon, MD, PhDPage 15 of 22BibliographyPeer-reviewed Articles1.Karon BS, Thomas DD. Molecular Mechanism of Ca-ATPase Activation by Halothane in SarcoplasmicReticulum. Biochemistry. 1993; 32:7503-7511. PMID: 83933422.Karon BS, Mahaney JE, Thomas DD. Halothane and Cyclopiazonic Acid Modulate Ca-ATPase Oligomericand Function in Sarcoplasmic Reticulum. Biochemistry. 1994; 33:13928-13937. PMID: 79477993.Karon BS, Nissen ER, Voss J, Thomas DD. A Continous Spectrophotometric Assay for SimutaneousMeasurement of Calcium Uptake and ATP Hydrolysis in Sarcoplasmic Reticulum. Anal Biochem. 1995;227:328-333. PMID: 75739544.Karon BS, Nissen ER, Kutchai H, Thomas DD. Anesthetics Alter the Physical and Functional Properties ofthe Ca-ATPase in Cardiac Sarcoplasmic Reticulum. Biophys J. 1995; 68:936-945. PMID: 7756557 PMCID:12818175.Shi Y, Karon BS, Kutchai H, Thomas DD. Phospholamban-Dependent Effects of C12E8 on CalciumTransport and Molecular Dynamics in Cardiac Sarcoplasmic Reticulum. Biochemistry. 1996; 35:1339313399. PMID: 88736076.Karon BS, Kempe KC, Scott MG. Heparin Interference with Sodium and Albumin Assays. Clin Chem. 1997;43(4):697-698. PMID: 91052807.Karon BS, Daly TM, Scott MG. Mechanisms of Dopamine and Dobutamine Interference in BiochemicalTests Using Peroxide and Peroxidase to Generate Chromophore. Clin. Chem. 1998; 43: (1)155-60.8.Clark AC, Karon BS, Frieden C. Cooperative Effects of Potassium, Magnesium, and Magnesium-ADP onthe Release of Dihydrofolate Reductase from the Chaperonin GroEL. Protein Sci. 1999; 8:2166-2176. PMID:10548063 PMCID: 21441369.Karon BS, Autry JM, Shi Y, Garnett CE, Inesi G, Jones LR, Kutchai H, Thomas DD. Different AnestheticSensitivities of Skeletal and Cardiac Isoforms of the Ca-ATPase. Biochemistry. 1999; 20:9301-9307.10. Fantz CR, Powell C, Karon BS, Parvin CA, Hankins K, Dayal M, Sadovsky Y, Johari V, Apple FS,Gronowski AM. Assessment of the DIagnostic Accuracy of the TDx-FLM II to Predict Fetal Lung Maturity.Clin Chem. 2002; 48(5):761-765. PMID: 1197860311. Winn-McMillan T, Karon BS. Comparison of the TDx-FLM II and lecithin to sphingomyelin ratio assays inpredicting fetal lung maturity. Am J Obstet Gynecol. 2005 Sep; 193(3 Part 1):778-82. PMID: 16150274 PMCID: 012. * Babic N, Chen LS, Karon

J. Jacob Kaplan Research Award - University of Minnesota Medical School 01/1996. Bradley S Karon, MD, PhD Page 2 of 22 NACB Distinguised Abstract Award - National Academy of Clinical Biochemistry 07/2006 AACC Outstanding Speaker Award - American Association for Clinical Chemistry 01/2009 AACC Outstanding Speaker Award - American Association for Clinical Chemistry 01/2010 AACC Pediatric and .