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//J CALIFORNIATUMOR TISSUE REGISTRY.,pcTOBER199 ,.Ca lifornia Tumor Tissue Registryc/o: Oepnrtmeot of l'athology and Human AnatomyLorna Linda University School of M edicine11021 Campus Avenue, AH 335Loma Linda, California 92350(909) 558-4788FAX: (909) 558-0188E-mail: cttr@linkline.com
TMn:et auditnrt:Practicing palhologists and pathology residents.Goal:To acquaint the participant with the histologic features of a variety of ben ign andmalignant neoplasms and tumor-like conditions.Ob jectives:The panicipunt will be able to recognize morphologic features of a vuriety of benignand malignant neoplasms and tumor-like conditions and relate those processes topertinent references in the medical literature.Educational methods and media:Review of representative glass slides with associated h islories.Feedback on consensus diagnoses from participating pathologists.Listing of selected references from the medical literature.Principal faculty:Weldon K. llullock, M0Donald R- Chase. MDCMECredit:Loma Linda University School of Medicine designates this continuing medicaleducation activity for up to2 hours of Category I of the Physician's RL eognitionAward of !he American Medical Association.CME credit is offered for !he subscription year only.Accreditation:Lama Linda University School of Medicine is accredited by the Acered italianCouncil for Continuing Medical Education (ACCME) to sponsor continuingmedical education for physicians.
CONTRIBUTOR: Nelson Quigley, M.D.Anaheim, CACASE NO. l OCTOBER 1999TISSUE FROM: Frontal lobeACCESSION #28386CLINICAL ABSTRACT:After developing progressive mental slowing and left hemiparesis, this 64-year-old Asianfemale was found to have a mass in the region of the right frontal lobe. CT scan and MIU showed alarge contrast-enhancing mass that involved the right poSterior frontal lobe undemeat h the coronal ·sutnre, extending toward the motor strip, with major midline shift and brain compression.GROSS PATHOLOGY:The resected rwnor formed a I I 0 gram aggregate white-tan granular tissue fragments.CONTRrBUTOR: Mark JanssenAnaheim, CACASE NO. 2 OCTOBER 1999TISSU E FROM: Left occipital lobeACCESSION #28292CLINICAL ABSTRACT:An episode of right-sided weakness and right hemianopsia led this 54-year-old black male toseek medical attention. MRJ revealed a large left occipital tumor with evidence of hemorrhage withinthe tumor.GROSS PATHOLOGY:The specimen was received in multiple parts and formed an aggregate ofaboui 4 em of pinkwhite tissue fragments.
CONTRIB UTOR: Kenneth WoUesen, M .D.San Berna rdino, CACASE NO.3 - OCTOBER 1999TISSUE FROM: Seco nd metacarpalACCESSION #28384CLIN ICAL ABST RACT:This 21 -year-old male presented with a two-year history of a slow growing tumor in the dorsalradial aspect of the right hand. Radiographs showed a multiloculated cystic lytic lesion covering aodenalrging the shaft of the second metacarpal, with an overlying son tissue mass.GROSS PATHOLOGY:The 17 gram specimen consisted of irregular red-tan to tan-brown and yellow-11m tissuefragments.CONTRI BUTOR:elson Quigley, M.D.Ana he im, CATISSUE FROM : Right thighCASE NO. 4 - OCTOBER 1999ACCESSION #28285CLlNICA L ABSTRACT:This 86-year-o ld Latino male complained of a slowly enlarging mass on the inner aspect of hisright thigh. At surgery. !he nodule was intimately associated with the greater saphenous vein.GROSS PATHOLOGY:A 4.2 gram, rubbery, pale yellow-tan, eUipt ical mass 2.0 x 1.5 x 1.4 em. Sectioning showed afaintly whorled. white. fairly homogeneous mass with a slightly softer central area.SPECIAL STAINS:Ki67DesminI0% of cells are positiveStrongly positive
CONTRIBUTOR: William P. Snider, M.D.West Covina, CACASE NO.5 - OCTOBER 1999TISSUE FROM: ShoulderACCESSION #25268CLlNlCAL ABSTRACT:A 13-year-old Caucasian female noted a pea-sized nodule on the lateral aspect 1fthe rightshoulder. A month later the nodule had enlarged and an excisional biopsy was performed.GROSS PATHOLOGY:The 2.5 x 2.2 x l. 7 em palenod lehad a mottled soft interior.SPECIAL BUTOR: Wafa F. Michael, M. D.Fontanu, CACASE NO.6 - OCTOBER 1999TiSSUE FROM: Ova ryACCESSION #24021CLINICAL ABSTRACT:An ovarian cyst was removed from this 54-year-o ld female.GROSS PATHOLOGY:The specimen was partially solid, partially cystic. The cystic areas contained gelatinouscolloid-like material.
CO NTRiBUTOR: Frank DeG regorio, M.D.Sylma r, CACASE NO.7 - OCTOBER 1999TISSUE FROM : Left adrenalACCESSION 1127930CLINICAL AJJSTRACT:Flank and abdominal pain brought this 48-year-old obese female to medical anention. CT scanshowed a mass in the left adrenal gland.GROSS PATH OLOG Y:The 263 gram specimen measured 9.{) x 7.5 x 5.5 em. The cut surface showed dark brownhomogenous tumor and a 2.5 em portion of normal adrenal gland.CO NTRIBUTO R: LLUMC Pathology Group (mra)Loma Linda, CACASE NO. 8 - OCTO BER 1999TISSUE FROM: Left adrenal glandACCESSION #28550CLINI CAL ABSTRACT :This 7-year-old Caucasian female presented with headache. nausea, vomiting, dehydration andabdominal pain and was found to be in hypertensive crisis. She had a history of seiZI!re disorder.Work-up found an enlarged left adrena l gland.GROSS P ATHOLOGY:The 23 gram. 8.0 x 4.0 x 3.0 em adrenal gland contained a 4.0 x 3.5 x 3.0 em encapsulatedspherical tan-brown mass. The cut surla ce of t he mass was yellow-tan and brovm-tan mottled witnintermixed hemorrhagic foci.
CONTRIBUTOR: Janice Tiller-Borcich, M.D.Orange, CACASE NO.9 - OCTOBER 1999TISSUE FROM: Left neckACCESSION #27786CLINICA L ABSTRACT :This 34-year-old male patient developed a soft palpable mass in the neck near the carotidartery. An excisional biopsy was performed.GROSS PATHOLOGY:The mass measured 2.0 x 1.5 x 1.0 em and was thinly encapsulated. The cut surface washomogeneous, firm. and yello w.·SPECIAL STAINS:CalcitoninChromograninCAM 5.2positivepositivepositiveCONTRrBUTOR: Philip C. Robin son, M.D.Boynton Beach, FLCASE NO. 10 - OCTOBER 1999TISSUE FROM: Bowel mesenteryACCESSION #28290CLINICAL ABSTRACT:For the past two years this 82-year-old Caucasian female had complained of intermittentdiarrhea. She had lost about ten pounds over the few months. Colonoscopy revealed an abdominalmass in the left upper quadrant.GROSS PATHOLOGY:The specimen consisted of a 650 gram, 15.0 x 13.0 x 7.9 em portion of bosselated tan-pinktissue with areas of adherent yellow adipose tissue. Mult iple cut sections demonstrated a central areaof hemorrhage and necrosis with surrounding gray to tan lobulated rubbery tissue.SPECIAL STUDIES:S-100Clu-omograninA 1/A 3 keratinfocal ly positivelocally positiveDiffuse strong positivity
CALIFORNIATUMOR TISSUE REGISTRYGENERAL PATHOLOGYMinutes - Subscription AOctober, 1999SUGGESTED READING (General Topics from Rtctnl Literalun):The Emel'ging Molecular Genetics of Sarcoma Trrutslocations. Ladanyi M. Diag Molecular Parho/1995;4(3): 162·173.Tumor Suppressor Genes. A Short Review. Yeo CJ. Surgery 1999; 125(4):363-366.Treatment and Local Control of Primary Extremity Soft Tissue Sarcomas. Kurakousis CP and Dlriscoll DL.Joumal Surg Onco/ 1999, 71: 155-161.Stereotactic Brain Biopsies Specimen Preparation and Evaluation. Burger PC and Nelson JS. Arch PathollAb Med 1997: 121(5):477-480.California Tumor Tissue Registryc/o: Department of Pathology and Human AnatomyLorna Linda University School of MedicineI 1021 Campus Avenue, AH 335Lorna Linda. California 92350(909) 558-4 788FAX: (909) 558·0 188E-mail: cttr@linkline.com
Case No. I, Ac essioo No. 28386October 1999Bakersfield San Joaquin Communjtv tlospitall Fibroblastic meningiomaOrange CUCJ Medjcnl Center RcsidaJL\) - Pilocytic asiroc)'lomaVentura !Unil!lbl - Pilocytic astroc)toma (2)Santa Rosa - Meningioma (2)Mountain Vi w EI Camjoo l losnit!l!l - Meningioma., fibrous typeLong Beach - MeningiomaSunUt Barbara Couagc Hospita)) - MeningiomaOakland (Kaiser) - Meningioma, libroblastic (2)Son Diceo CNayal Medical Center! - Fibrous meningioma (13)Mootcrcy !Community Hospital of Monterey Peninsula) - MeningiomaNeb!aska fCrcightool - Meningioma. fibroblast typeWisconsin Madison - f ibrous meningiomaTexas Texn." Tcchnjc;u! Medical Hlth Ctr) - Meningioma, uggrcssiveflptjda !Ocala) - MeningiomaMichigan St. Joscnh Mercv Hospju\ll - Malingioma (5)Michigan Oa!cwoocf! - MeningiomaOhio (Da"on) - MeningiomaOhio McCu!lougb-l l.yde Memorial HosnitnD - MeningiomaNorth Carolina IAsbcryjl!cl - Mcnin&iomn (2)Loujsiana fShrcvcoonl - MeningiomaMo.rvlnnd fWocx!bjnc\ - Meningioma (2)Pcnnsl'!\ll!!ia C!.ebjah Vallcv liosoiJAII - Fibroos ngioma (I); Meningioma. fibroblastic (I); Meningioma,uansiticnal type {with chlllllCieristie whorls of tumor cells) (I); Meningioma (2)Pcnnsvl\·anja (Allegheny General trosnjtull - Meningiomal cnnsvlvan i a CConcmuugh Memor!nl llospimll - MeningiomaNew York Nonhooal - Meningioma, tl'llllsitional typeNew York (SUNY S!Ony Brook Univcahy Hosnital\ - Meningioma, fibroblastic t -pe (9)New Jer.;ev O ttlook Hosoital\ - Meningioma (2)Mn:s erbugn.s Berkshire Medical Cemql - Meniogjom:tConnectiCUt OJnjvcajty Connecticut tilt O r) - Fibroblastic meningiomaCanada Cfoo1hlllllospita!l - Pilocytlc IL"rocytomaCanada CVGH Anutgmic P@lhofogyl - Meningioma with increased mitotic ncrivitySuudj Arabia (King Khaljd lJni\'ershv Hospital) - Fibrobla."tic meningiomaJapoo fShimda Cjty) - Fibrous meningiomaJonan fKU!l!Shiki) - Meningioma. fibroosNorth Ireland (Ahnaoeluinl - Fibroblastic meningiomaDIAGNOS IS:Fibroblastic MeningiomaTYOIII, M95320REFERENCES;de Ia Monte SN. l listologic Features Predicting Re .'Urrc'OCO of Meningiomas Following Subtotal Rcse.1ion. Am J SurgPatho/1986; 10(12):836-843.Kcpes JJ. Presidential Addrc! S. 'lllc I istopathology o!'McningiomiLS. A Rc0c 11on o!'Origins nnd l; xpecwd Behuvior'lJ of:Veuropmhol a11d Exp Neurcpar, 1986; 45;95-107.Mc:is JM. Meninajomas. An lmmunobistocl1emical Study of SO Cases. Arch PathollAb Mf.'d 1986; 110(10):934-937.
Ca e No. 2, Accession No. 28292O clober 1999Bakcrsljeld ISan Joaquin Communitv Hgsol!@ - Gliobla. roma multifonncOronoe ll!CI Medical Cemer Residents) -Anaplastic oligOOendrogliomaVenrura !!Jnil@bl - Olisodcn8roglioma (2)Santa R05a - Oligodendroglioma anapl .tic (2)Moontoin Yiew fEI Cumjno !·losnital) - Anaplastic oligodendrogliomal&no Beach - 11igh-81lldo maliJlllllnt a. trocytoma (glioblastoma multiforme) (6)Sa.nta !lijrbam (Cottage liOl!pi!!l!l - AnapltL!tic oligodendrogliomaOakland IKAigr) - Glioblastoma multi forme (2)San Qjeeo CNa '31 Medico.! Center) - Glioblastoma multi forme (13)Montm;y ICommunjtv t!Q;mital ofMomu:rsy Peninsula) - OligodendrogliomaNebra ka Crej!!htonl - O!igodcntroglinmaWisoonsjn (Madison) - Ml ed oligoastroeytoma , grade 4Texa. CT!lXa.! Technical Me4ical Hlth Ctrl Florida C e!j!l - Glioblastoma multifonncMichi8!1Q ISl Joseoh Mercy Hospital) - Glioblas10ma multi forme (5)MjcbjgM (0Jl:woodl - Necrotic neoplasm, oonsistent with high grede gliomaOhio ID ytonl - Grade 4 fibrillary astrocytoma (Glioblastoma mt tiforme "GI3M")Ohio IMcCullough-Hvde Memorial Hn pl!al) - Anaplastic oligodendrogliomaNonh C!!roljna IAshcrvillel - Glioblastoma multifonne ( I): Glioblastoma. possibly arising in oligodendroglioma (I)!.ouj iw IShreyep!l!ll - Glioblasloma multi formeMaryland I Woodbine) - ASirOC)otoma (2)Pcnnsylynoja !Lehigh Vnl!cy Hospital) - Anaplastic astroe)toma grade !VIII! consistent with areas ofoligodendroglioma ( I); Glioblastoma multilorme with areas of oligpdcndtocytc-like features ( I); Glioblu.,tomumuhifonno (highly maliJllla.ota.stroc)1omo, grades Ul to IV?) (I); Glioblastoma multili rmc (2)PenmvlwnjaiAJieghenv General HospitW) - Anaplasaic oli codrogliomu with areas of glioblastoma multifonnePenmvlvnnja IConemaueh Memorial Hosoiudl - Gliobl.toma multi formeNew York rNorthOOr\) - Glioblastoma multi formeNew Ymk !SUNY Stony Brook Unjver ity I!ospital) - Mullgnant oligodcndroJllioma (9)New Jerncy IOverlook Hosoi!!lll - Glioblastoma mulli fi mle (with mixed astro-oligodendroglioma components (2)Massarhu:set!S fficruhire Mc!licaJ Center) - Glioma gr.ulc IWW with astrocytic and oligodcndroc)1ic ditfcn:ntiotionConne!:!i vt CUni itv Connectiart Hit Ctrl - Aonplllstic oligoostrocyUlllla 'S glioblastoma mulrifurmcCan!l4a {fOO!hjll Hosnitnll - Mixed malignant glioma (oligodcndrogliomatOU and a.strOC)tic aJiobla.stoma multiforme1ike components)CamldaiVGH An!llomlc Pothologvl - Anaplastic oligodendrogliomaSaudi ArubjafKing Kh::t!jd Uni\'epjiLv Hospjtill) - Glioblastoma multironnc nrising tJ·om oliFCJendrogliomaJam !Sbjmda Citvl - Anapl!lStic oligodendrogliomaJaD!UJ IKu!l!.lhiki) - Gliobi!IS!omamuhiformcNonh In: land (A!tn!ljlOIYilil - Glioblastomn multilormcDIAGNOS IS:GLioblastoma M ultiformeTX2400, M94403Consultation: Boleslnw Liwnicz, M.D., Ph.D . Neuropathologist: ''G lioblastoma Multi forme."REFERENCES:a PC and Gn."en SB. P111icnt Age. HiSiologic F urcs and Length ofSurvh·aJ of Patients \\ith Glioblastoma.Canctr 1987; 59(9):161 7-1625.Surg r PC. The Use of the Monoclonal Antibody Ki-67 in the Identification of Proliferating Cells. Application toSurglcul Neuropathnloc,y. AmJSurs Pathol 1986: 10(9): 11-6 17.Giangaspcro F and Burger I'C. Correlation' Between ()lologic Composition und Biologjcol llchavior in GlioblustomaMulti forme. A Postmortem Study of SO Cases. Cancer I 983; 52 ( 12):232()-2333.Schmidt EE. CDKN2 (pi6/MTSI) Gene Deletion or CDK4 Amplification Occurs in the M:ljorityofGiioblastomaCancu Re. 1994: 54(24):6321-6324.
Case No. 3, Accession No. 28384October 1999B!!kersfield (San Joaquin CommunitY Hospi!!l!) Gillllt cell rumor of tendon sheathOranl!!: CUCJ Mcdjel Center Re jdm!Sl Ginnt roll tumor oftatdon sheathVentl!nt (\Jnilabl Giant cell tumor of tendon sheath (2)Sanm Rooa Ginnt cell tumor or tendon sheath (2)Moumojn View IE! Camino Hospital) Giant cell tumor of tendon shcatl1 (nodular tenosynovitis)Long Beach Giant cell rumor (6)Sanm Barbara ICqunge !1ospi1Qll Chondromyxoid fi brQn nOa!cland {Kaiserl Giant cell tumor (of tendon sheath) (2)San !?jcgo CNawl Medical \.entql . Giant roll reparative granuloma ( IJ)Montm;y Community Hospjtal ofMonterer Pcrtinsulal · Giani oell tumor tendon shcalbNebrw;ku ICrcioh1onl Gillllt cell tumor of tendon shcUlh\Vi;;oonsjn (Madisgnl Giant cell reparative granulom" small bone. handTexas Texas Technical Medical !11th Orl Florida (Ocala) T .-nosynovia! giant cell tumorMichjllliO 1St l o!fCph Mercy Hosoitull Giutll cell rcpllrtuive granulorno (5)Micl!i!llln COal:w09dl Giwn cell tumor of tendon sheathOhio (()ayton} Ancurysmol bone: cystOhio fMcCu!lo11eh !!vsle Memgrj Hosnita!l · Giant cell tumor of boneNorth C.volina (Mbcrvillc) · l' iSI"entod villonodular t.enoS)'llOVitis (ginnt cell tumor of tendon heath) (2)LoyjsiM I S!yevell!l!'!) RIO par.tth)roid h)pCIJllasia, DID gi301 cell rumorMarvlnnd (Woodbjncl Giant cell rumor (2)Pennsy!VIIIlia Cl&hjgh Valley I !oopitull · Oinnt cell tumor of bono (I); TcnOS}'llOviul gi301 cell tumor (I); Mulignantgiant cell tumor with nwncrous hemosiderin deposits tllld invasion into adjacent librocollagcnous C.T.) ( I ); Giant cellrumor of don shcollh (2)Pennsylvania IA!I AA nv Gq!era) Hoopj!ll!l Aggressive gim cell tumor of soft tissuePennsylvanin Concmnugh Memorial HosnjLQI) · Cia.nt cell tumorNew York INorthoortl Gisnt cell tumor of tendon sheathNew York CSUNY Stonv BrocX Uni 'ClSity I!o:mitall Giam cell tumor of tendon sheath (9)New Jcmey (Overlook HospitaQ Nodulor tenosynovitis (2)Massncbusetts CP!uslieldl . Giont cell tumor of tendon sheathblnnecticut (University Conncs.1icut Hlth Ctr) - Giant cell tumor of tendon sheathCanada IFOO!hill BOM!jtaJ) ChondroblastOmn (vs. Giant cell rumor. etc.)Canada/VGH AnUIQllliC Pathology! Giant cell tumor of tendon sheothSaudj Arubja (King Khaljd {Jnjvcr;tity Ho.spitu!) . Giant cell tumor of boneJaoan C himda Cit)') . Tendos)novia! giant roll rumorl8!l!l!! CKumshikj) Nodular tcnoo)novitisNonb lrclund CAI!nu cluinl · Giant cell tumor of tendon sheathDIAGNOSIS:Giant Cdl T umor, p ro bably of osseous originT l l540. M692!0Directors Note: RJidiographs showed ex1ensive in volvement of the melacarpal bone. Most study setslides were of the region of soft tissue involvement. Origin in teoosynovial tissue cannot be ruledOULREFl; RijNffiS:Gupta S. eta!. Giant Cell TUJt1()Ur ofthc First Metacarpal Bone. Hand 1980; 12(3):288-292.McGcoch CM, ct nl. Osteoclastoma of the First Metacarp l. J Hand Surg (Br) 198S; 10(1):129·130.Carlow S!l. Metacarpal Resection with a Contoured Jlioc l onc Groll and Sili0011c Rubber lmpltlnt for Mc nca!1J'll GiantCell Tumor. A Case Report J Hand Surg (Am) !98S: 10(2):275-278.
Cnse No. 4, Accession No. 28285October 1999Bakersfield ISag Joaquin Community Hosnital\ · LeiomyosarcomaOmnoc IUCI Medical Center Residalts\ Leiom)'OS8rOOmaVentura CUnilabl Leiomyooan:oma {2)Santo Rooa Leiomyosarcoma (2)Moumain Vjcw lEI Camjno Bosnitall . LeiomyosarcomaLooa BI.'Pcb Leiomyosarcoma {6)S nm IW!wn CCouage Hosojta! l LeiomyosarcomaOak lund (J ujgr\ · Leiomyosarcoma (2)S:m Qjean CNayal Medical Ccnt :rl · Leiomyosnrooma ( 13)Momcrcy Community Hosoilal ofMqmerey l'eninsuln) . Lciom)'05arcomaJ:ik)n:o.sko CCrc!ghtonl . LeiomyosarcomaWjsoonsjo fMndjson) . Primary sarooma of greater sophenous vein (LMS)Texas (Texas TecbnjCill Medical Rlth Cr\ Leiom}1 Sai'C()muFlorida(Oculal l.ciomyooarcomaMichjpn lSt Joseph Mercy Hosnimn . Leiomyo.arc()ma. urising in \'ein (5)Michi!!i\0 COak!wqod llosnital\ Intravenous leiomyosaroomoMjcbhmn CDauwl · LciomyosarmmaOhig CMcCI!!!rug!J-Hy!le Memorial FIO!!pitall Leiomyosarcoma ("'oous)North Cwo!jna (Ashcryjlkl l.eiomy053r00fT\a (2)Looisiw CSbrcyeoonl - Leiom)'osareomaMaryland Woos!bincl · Symplastie leiomyoma ( I); Pleomorphic leiomyooarooma (I)&nnsylynnjol! .chigh Vallev Hoopilllll · Leiomyosarcoma (I); Sympi11Stic leiomyoma ( I) ; FibrolipOSoteoma (ofthigll)or hish 8f00e (highly malignant) fibrolipOSaroom:t of mixed fobroblustic and lipoblastic type (I); Lciomyo!lllrcoma (2)Pcnnsylvnoin CA!Icghenv General Hospital) · Lciomyosnr :OmnPcnnsylvunjq CCons:mnugh Memorial Hospital) LciomyosurcomoNew york ( Northoonl - L-eiomyosarcomaNew Ymk IS!JNY Stony Brook Universiw Hospital) l.eiomyosarcomu (9)New Jmcv COycri X k Hosoita!l · Intravascular lciomyo oomn (2)Mas*achuscus!Berkshire Medical Center) Angioleiomyo llroomaCtmneplicut Cllnjvcrsitv Communi tv H1lh Ctrl - Low grade JeiomyosaroomaCanada !FOQ!hjl! l!ospital\ Cellular scbwannomaCanod!l VGH Anatomic PathoiO!!V\ · LciomyoSl!loomaStwdj Arahja !Kjng Khalid Unh i!V Hospjll!!l · Leiomyosarcoma in a I)mph node (4): Rhabdomyoooraxna in olymph node (2)JaQ!IO !Shimsla Citvl - VIISeular leiomyosnn:cmn)pp!l!l CKum.thikil Bizarre leiomyomaNonh !rc!wu.l (Aitnagcluinl - Symplastic leiomyomaOIACNOS IS:Vttscular Leiomyosar coma, R ight Saphenous Vein1"49530, M88940REfl1!li\ NCES:l lughcs S. A Case of Leiomyosarcoma of the Long Saphenous Vein. Jlo.rc Sw·g 1973; 7(2):7 1-73.Hltlnphrcy M. Leiomyosarcoma ofthe Saphenous Vein. A Case Reponru1d Review of the Literature. J /Jone Jomt Surg1987:69{2):282-286.Kholifa IIA. et nl. Leiomyosarcoma of the Rc:clum. Reportea. and Review of the Literature. Di. CoiOII Reclllm1986;29(6):427-432.Sag!ik Y. U:iomyosor :omaofthe Great Saphenous Vein. 1111 Onhop 1992: 16(2):185-187.Jemstrom P. ct al. Leiomyosarcoma of the Long Saphenous Vein. Am J Cli11 Potilo/1915; 63(1 ):25·3!.Kevorkian J. ct al. Leiomyosarcoma of Large Anerics and Veins. S.rg 1973; 73:390-400.or.
Case No.S. Accession No. 25268O rrobu 1999Bakersfield (Sap Joaquin Community tlo:mital) Malisnnnt schwnnnomaQrange (lJC! M!Olical Center Rcsideol§l Cellular schwannomaVemura IUnilab) Cellular neurilemmoma (2}Sania Rosa Atypical newogenic tumor, ruleoLJt malisnant peripheral nerve tumor ( I); NcurofibroslltCQmaMounf!!in View EI Camino Hosoita!) Cellular schwnnnomaLong Beach Malisnant nerve sheMh tumor (schwannoma) (6)Santa Barham Cottn&e tlospitall Cellular schwannomaOaklood /Kai!Sr) Cellular schwnnnomu (2)San Dieb'( (Na, ol Medical Center\ · Malisnant peripheral nerve sheath tumor (13)Monterev fCommunitv Hosoita)gfMomerev Peninsular) NeurofibromaNebraska ICrciobtonl NeurofibromaWisconsin fMadjson\ Neurofibroma, focally c::cllular ? neurofibromatosisTexa.s (Texas Technical Medical Hlth Or) Schwannomaflorida IOcain\ Desmoid tumorMjcbigan 1St. Joxnh Men;y Hospita]l Mtllisnant P"'iphcral nerve sheO!h tumor (3); Neurofibroma (2)Michigan Oakwood HmnitaJl SchwanoomaOhio @Ylon\ Neurogmic sarcomaOhio (McCullouob·Hydc Memorial!iosQitall · Cellular 5 hwntlllomaNorth Carolina IA hervil!e\ · Malignant peripheral nerve sheath tumor (2)Louisiana CSbrcycpprt) . NeuroHbromoMU!Yiand IWMC!bjnc) Ncurolibromo with focal maligmmt ch011ge ( l ); Neurofibroma (I)Pennsvlvania !Lehiob Valley Hosoihlll Malignant peripberol nerve sheath tumor (2): Cellular schwannoma ( I);"Desmoid rumor" of low grodc fibrosarooma (with areas of mitotic aaivity) (I); Neurogenic sar Oma ( I)PeoQ.'ivlvunia (Allsahcny General Hospital · NeurofibromnPcnnsv!vanja Conemaugh Memotitll HospiUlll . SchwannomaNew York CNorthnonl · Cellular schwannomaNew York !SUNY Stony Brook Unive!l!jlY Hospital\ Schwannoma (9)New Jmey !Overlook HospiUl!l · Ncurofibrosarooma (2)Massad!wctts CBmshire Medical Cert!erl Malisnam peripbc:ml nerve sheath tumorConnecticut CUnjyecjtv Comnnmity tilth Ctrl · Neurofibroma with malignant potentialCl!ng4a Foothill Hospila!l . MPSNT vs. cellular scbwunnomoCon!lda IVGH i\nntomjc Pathology) Molisnant pcripher nc ve sheO!h tumorSaudi Arabia (Kjog Khalid University Hosnitall · Malignunt pc:ripheraJ nerve sheath tumorJail!!!! !Shimd CjM · Low-grade MPNSTJapan (J ura hil;j) Malignant periphcnll nen'e shelllh tumorNorth In:laod IA!rnogcluin\ · Malisnant peripheral nerve sheath tumor.DIAG NOS IS:Low Grade Malignant Peripheral Nerve S heath Tumor (M !'NST ), ShoulderTY 1220, M95603REFERENCES:Saenz NC, ct a!. Neova."ularity and Clinical Outcome in High-Grade Extremity Soft Tissue SaroomtlS. Am Surg Onco/I998: 5(1):48·S3.Blair SL, et lll. Multi focal Extremity Sarcoma. An Uncmnmon and Controversial Entity. Ann S11rJ{ Onco/ 1998; 5(!):37-40.Brooks AD, et a!. Superficial Extremity Soft Tissue Sarcoma. An Analysis orProgoo:;tic Factors. Am Surg Onco/1998;5(1):41 -47.Ooimaru Y, et al. Mnlisnanr Pc:riphenl rw-,., Sheath Tumors (Malignam Schwnnnomas). An lmmWlCJbi tochemicalStudy of29 Cn.,s. Am J Swg Pathol !985; 91434-444.Ducatmllll BS, ct a!. Mnlisnantl'eriphcral Nerve Sheath Tumor. A Ctinicopathologic Study of 120 Cases. Cancer 1986:57:2006-20021.
Case No. 6, Accession No. 24021Ocrobu 1999Bakersfield CSan Joaquin Comnmnity Hospit.oll - Struma ovoriiQrange C!JCI Mc:dical Cemq Resident Scrtoli cell tumorVennn 1\Jni!abl · Struma ovurii (2)Ssnla Rma Cj. tie ter.uoma with Senoli cell tumor (2)MouQipln View CEJ Camino Hospitall · Struma ovariiLong lle!leh Struma ovtlr ii (6)Santa Bnrbqra CCottage Ho nitall - Mature cystic teratoma " th strumaOaldand CKajserl Suuma ovarii (2)San Ojc1!9 CNaval Medical Center) · Struma ovurii (10); Stnlmal eareinoid (J)Momercy CCommunitv HQ3pjtalofMontcrey Pepinsu!a) - Strumaovari iNebraska !Creighton) Scrtoli cell tumorWisopndn Madison) - Scrtoli-Lcydig oell tumor vs. strumu ovuriiTexas CTm Tcdmic:a! M dic:a! Hlth Qr) Struma" oYBriiF1orid.1 IOc:alal Sc:rtotH.cydig cxlltumorMichigan !Sb Jooeph Mercy !-lospital) Strumal carcinoid (S)Michigun (Qnkwood 1-lnspitul) Strumu ovu.riiOhio 1Po 1onl · Slfllma ovclfii .Ohjo IMeCul!ough-H\Jie Memorial twpilall · Suuma oYllriiNonh Camlina CAshenillcl . Slfllma ovarii (2)Louisjano !Shrcveoool Sertoli-leydig cell tumorMarvland !Woodbine) · Strwu d carciltold (2)PennsyiVll!lia ILcbigh valley Hosoilal) Struma ovarii (2); Struma ovurii adjacent to bcni8J1 thyroid adenoma ( I):Struma ovurii with eorcinoid (2)Pennsy!Vll!lja Allegheny Genern! Hospjtol) Suuma ovariiPennsylvMiu (Conem!lllgb Memorial !-lospitu!l Slromul ovuriiNew Yor!s INorthoort} Struma ovarii with clear cell fc:tlurosNew Yort /SUNY Stoov Brook University Hospital) · Struma ovarii (9)New Jcpcv (Overlook Hospital} · Struma O .U (2)Massar ugns ffierlsshin: Ms;dic:a! Center) Tumor ofWolffian origin(!); vs. Senoli cell tumor (7)Conncs.1icut !Unh·crsilY Communitv HJth Clt) - Struma ovarii with folliculllt neoplasm, probnb1y variant ofrapillarycarcinoma \'S. struma cnrcinomaCanacJa Cfoolhill Hospitull Struma ovurii (with granulosa ?all tumors)Canada (VGU Anatomic Patholoev) Struma ovariiSaudi A!pbia CKjns Khaljd Vnjvep;itv Hospjl!l)l Senoli-lcydig cell tumor of ovary. well- liffcn:ntiated,!;lpan !Shimda City) · Stntmal carcinoid tumorJapan cKunl ihikil - Strumn O''ariiNorth Ireland Ah:nagelujnl · Struma ovariiDIAGNOSI S:Struma OvariiT87000,M8590 lREfERENCES:Dohkc M. Suuma Ovurii. MR Findings. J CQmpw Assi. t Tomogr 1997; 21(2):265-267.Caruso PA, al. An Intense Oinieop;uhologlc Study of JOS Teratomas oflhe (Nary. Canc:.r 1971; 27:343-348.farrell, OJ. et al. Hashimoto's Disease inn l)enign tic Teratoma of the Ovary. HislOfX1llrol i99l; 19:283-284.Szyfelbcin WM. ct al. Cystic Struma Ovnrii A Frequemly UnrcCO!l/lized T111nor. A Report 01'20 Cases. tfm J SurgPal/1011994; 18:785-788.
Case No. 7, Acc.ession No. 27930October 1999Bake.sfield (San Joagujn Communjtv Bospitql) MyelolipomaOrw ge !UCI Medical Center Resjd\1)\Sl . MyelolipomaVentura Ugjlob\ Adrenal myelolipoma (2)SQQ)D Rasa Adrenal myelolipoma (I): Myeloid metaplasia (myelolipoma)Mountain Vjcw CEI Crunjoo 1-losnjran - Mycl lipomoLooa Beacl! . Myelolipoma (6)Santa !larbora Co!tase HosoiU!Il MyelolipomaOukllllld IKoiser} . Myelolipoma (2)StUJ Diego /Naval Mcdicul Cemer) Myelolipoma (13)Monterey Communitv HospiU!I of Monterey l'&ninsu!al Extramedull:uy hema!opoic:sisNebraska ICn;ightonl MyelolipomaWjsconsjn (Mudison\ MyelolipomaTCl!usiTcxas TeclmicaJ Medical Hhb Cul · ' Myelolipomaflorida IOen!a) MyelolipomaMjchigan ISJ. Joseph Mcroy Hospila!\ . Myelolipoma (5)Mjchiean COJ!swood Hospital\ M)'ClolipomaOhio ffia'ltoo\ MyelolipomaObjo !McCy!!ough-Hydc Memoriol Hospital! MyelolipomaNorth Carolinq (Ashcrvi lle\ Myelolipoma (2)Louisiana !Sbrcvcponl M)'CiolipomaM"D'Iand {W09dbjne\ Myelolipoma (2)Pl:nosylvnoln !lehigh Yullcy HospjJall Adrenal myelolipoma (4); Cw-cinomn of adrenal &lund ( I)Pcnnsylwnja (Allegheny Gcne!1!llimpita!) Myelo!ipomuPenosvlvnnja !Conemoush Memorial HospitaO MyelolipomaNew York CNorthoors\ MyelolipomaNew York ISl!NY Stony Brook Unjversitv Hospital) Myelolipoma (9)New Jersev (Overtook Hospital\ Adrenal m) :lolipoma (2)Mmchusctt3 Berkshire Medicu) Cemerl · MyelolipomaConnccljcut llJnivenjty Community Hhh Ctr) MyelolipomaCanada Cfoo!bil! tl pjto!l · Granu! 1ic saroonuLCunada CVQH Anatomic Putholoov) MyelolipomaSi!udi Arabjp !King Kl.,!jd Uni ycr:;jty Hospi)all Myelolipoma of adrenal glandJaoon CSbimda Citvl MyelolipomoJapan Ku!ll.'!hiki\ MyelolipomaNonh Ireland !Aitnagclujn\ My lolipoma adrenal glandDIAGNOSIS:Myelollp lma, Adrenal GlandT93000, M88700REFERENCES:Boudreaux 0, Waisman J. Skinner DO. ct nl. Giaot Adrenal Myelolipoma and Testicular Interstitial Cell Tumor in aMan with Congenitai2 1-Hydroxylasc.f}eflclcncy. Am J Surg Patho/ 1979; 3(2):109-123.Goetz S. ct a!. Hematopoietic Elements Assoclntcd "ilh Adrenal Glands. A Study of the Spc :tnJm of Change in NineCases. Arch Patho/ Lab Med 1994: 118(9):895-896.Hunter SB, ct a!. El troadreoal Myelolipoma. A Report ofTwo Ca c:; . Am J C/in Pathoi 1992; 97:402.Noble MJ. et nl. Myelolipoma. All Unusual Surgical Lesion of the Adrenal Gland. Cancer 1982: 49:9 2.
Case No. 8, Accession No. 28550O c cober l999Bakerslicld l&w Joaquin Communjty Hospital\ Phcocbromoc)tomaOranse IUC! Medical Center Rcsldcn\;;l · Pheochrontoc)tomaVentura (Unjlubl . Pheochromoc)toma (2)Santa Ro a · Phcoc:hromocytoma (2)Mountain View El Camino HMnitall - Pheochromoc)1omaLong Bench Compooite phee :hromocytoma with ganglioneuroma (6)San1a Bnr!Jaro !Cottage HoopjJOil PheochromocytomaOakland IKniserl Phcochromcx:ytoma (2)San Diego INaya! Medical Ccntq\ Pheochromocytoma ( 13)Monterev CCommunitv Hospital oCMooterev Peninsula) Pbeochromoc)tomaNebmslg! !Crci!!htonl · Pheochromoc)tomaWjsoon in IMudjson) - Paraganglioma- Ganglia enlarge-d? Ganglione11romoTexas ITeya Technical Medical llhb Ctrl · PheochromocytomaFlorida (Qcg!ul ParagangliomnMichigan IS!. Joseph Macy Hoopj!i!ll Pheochromoc)toma (5}Michigan /Oakwood Hospita!l Pwuganglioma (pheochromoc)toma)Ohio IQa !ool PheochromocytomaOhio IMcCu!ls ugh-Hyde Memorin! Hospj!!lll . PheochromocytomaNorth Caro!inu IAsheryillel Pheochromocytoma (2)Louisjana ShreycoorL) - Pheochromocytoma'-'fary!and IWO!!dbincl · Parogana)ioma (2)Pennsv!Yll!!ja O&high Valley Hosoj!Bil Phcochromoc)toma (5)Pcnnsvl!'l!!lia (Allegheny Gencllllll pitall Pheochromoc tomaPennsylvanjn fConemru.Jgh McmorjW Hosnitall . PhcocltromocytomaNew York INortboortl Composite pheochromocytoma gaoglioneuromnNew York ISUNX Stony Orook University lio. pitu!) Pheochromocytoma with vascular invasion (9)New Jersev !Oycrlool! Hospital) Pbeocbromocytoma (2)Mass!!C'wsens CBcrkshi"' M dig!l Center) PheochromocytomaCon@jeut /University Communitv Hhh Ctrl · GMglloneuroblastomaCanada (foothill Hospj!i!ll · l'beocbromo oma (?Composite pheo - JOmc more immature areas upJ arenl)Canada !VOl ! Anatomic P!I!!Jologyl PheochromocytomaSaudi A[(!bia CKjng Khalid Uolyer:;jty HospitaJ) - Pheochromocytoma with ganglionet.Jromo (oompo.'\itc tumor ofadrenal gland)Japan (Shimda Cjtvl · PheochromocytomaJapan IKura hjkil PheochrornOC)1omaNorth Ireland IAitnaiY:Iujn) · PhcochromOC)tomaDIAGNOSIS:Pheochromocytoma, Left Adren al G landT93000,M87000REfERF.NCES:Epelbaum J, ct ul . Molecular om! Pharmacological Chaructcrization ofSomatostatia Receptor Suhl)'pC3 in Adrenal.ExuMdr '11al Mnlignnnt Phcochromoc)toma.s. J Clin 11Ciocrinol o[Merab 1995; 80{6):1
TUMOR TISSUE REGISTRY .,pcTOBER199 ,. California Tumor Tissue Registry c/o: Oepnrtmeot of l'athology and Human Anatomy Lorna Linda University School of Medicine 11021 Campus Avenue, AH 335 Loma Linda, California 92350 (909) 558-4788 FAX: (909) 558-0188 E-mail: cttr@linkline.com //J
