U.S. EPA, Pesticide Product Label, PHENO CEN GERMICIDAL DETERGENT, 03 .

Transcription

· .'UNITED STATES ENVIRONMENTAL PROTECTION AGENCYMAR'tOlivia D. Laird, Agent forCentral Solutions, Inc.3130 Brinkerhoff RoadP.O. Box 15276Kansas city, KS 66115Subject:Pheno-CenEPA Registration No. 211-25Your Amendment Dated September 8, 1993Dear Ms. Laird:This is in response to your addition of HIV-l virucidalclaims to the product labeling.The labeling referred to above, submitted in connection withregistration under the Federal Insecticide, Fungicide, andRodenticide Act, as amended, is acceptable subject to thecomments listed below. A stamped copy is enclosed for yourrecords.1. In the use directions for "Dental Instrument Use" foundon pages 18 and 19'of the proposed draft labeling, add thefollowing disclaimer statement (from the 6/4/93 FDA/EPAMemorandum of Understanding):This product is not to be used as a terminal sterilant/ highlevel disinfectant on any surface or instrument that (1) isintroduced directly into the human body, either into or incontact with the bloodstream or normally sterile areas ofthe body, or (2) contacts intact mucous membranes but whichdoes not ordinarily penetrate the blood barrier or otherwiseenter normally sterile areas of the body.2.A net contents statement must appear on the label.3 . Submit five copies of the finished labeling before theproduct is released for shipment bearing the amended labeling.'.,.801. t . .- . ."-1 . . . . . . . . . .DATC EM,. 1. .1A '1Il0lCCItICVIUIIIICIS. . .-. . .-- .- O,'IClA&. 'ILl COpy

· , .2If you have any questions about these comments, please callWallace Powell at 703-305-6938.Sincerely, .g l. .Product Manager 32Antiaicrobial Program BranchRegistration Division (7505e)Enclosure

C!!:NTER PANEL')(REQUIRED).PHENO-CENGermicidal/Detergent With Organic Soil FungicidalVirucidal·Formulated for EffectiveHealth Care Facitily SanitationACTIVE INGREDI N'IS:, . *IIPM. ,.· . .·03%TS. . . . . ,. . . .21%,. . . .4.30%INPIr,.1.3I%COHTAIN SODIIM ItIIIIIELlFf ADIIl1IIIIML m- Keep Out of Reach of ChildrenDANGER .542l'lI.am16UIIIIiSCIIY."IS&U"'SEPA EST. NO. 211.f(SoIEPA REG. NO. 211·25. , . . .' "

1Page 2\(LEFT PANEL)(REQUIRED)DIRECTIONS FOR USE!t is a violation of federal Law to use thisinconsistent with its labeling.CLEANING AND DISINFECTIONproductin a mannerFor broad spectrum disinfection of gram negative and gram u itivebacteria, including Pseudomonas aeruginosa, add 1/2 ounce PHENO-CEN to thegallon of water. Remove heavy soil or gross filth then apply solution witha mop, cloth, sponge or mechanical sprayer so as to wet the surface·horoughly. Allow to remain wet for 10 minutes and then let air dry.If.gher detergency is desired, increase dilution to 1 ounces per gallon ofwater. Prepare a fresh solution for each use.PRECAUTIONARY STATEMENTS. . . . . to . end AnMI.r. o. .DANGER. c . . - . c - . ."*-.,. .Do . In.,.Oft.,Ofon . .,. w.,.a. A. . . . . . . . a i 01 toed.AIimoft; . . dae*Ig. . . tNIId .STATEMENT OF PRACTICAL TREATMENTSF ' . .,.01 . ., tor .lnca.aI "*,15 . FOI .". CII AIMaw end . . . . . oa . iMIid . . CalphpIC:IM.-.NOTE TO PHYSICIAN. at.-;c-.PraoebI. . . . . . . . . . . . -r COMiIil tMI:*.,. and oonwIiIIQn lIMY liltSTORAGE AND DISPOSAL- .-- .Do NIl a. IIOiIOf . . , . . . . . . . . . . .8TCMAGI:--. . ., . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1. . . . .n.:.". .oral., .o.ce . IDOiI . AwIII I., . . a1 IIIn . . . . af,.'--. c : . n I I :e. to . . . . . . . . . . . . . ,., . . . . . . . .c.o.oI,."".,. . . . . . . . . . . . . . ' . . . . . EPA . .lUICONT. OIIPOIAL-T,. -fCIt . .,. b rwcydngoriceGi . OI' . . . al . . - y . orllidl . Of.' . IIf . IlnllIIIca .by-.,. .,OWIIaI .·,. A. a. . .1-1

51"(HEALTH CARE FACILITY USE)PHENO-CEN is a phosphate free, concentrated, hospital germicidal-detergenteffective in 10 minutes at 20 C, in the presence ofblood serum, usedto simulate organic soil. PHENO-CEN's multi phenolic formula is designedto clean, disinfect and deodorize any washable, inanimate, non-poroussurface in one easy step. When used as directed, PHENO-CEH is strongenough to kill a broad spectrum of pathogenic bacteria, yet it is mildenough to have no harmful effects o the surface being disinfected, whenused as directed.5'(IENO-CEN is recommended for use by hospitals, nursing homes and anyhealth care institutions that are dedicated to controlling the hazards ofcross contamination in their establishments.For use on any hard,inanimate surface in patient rooms, restrooms, halls and public areas oncarts, bed frames, walls, floors, stainless steel, porcelain, glass andchrome.PHENO-CEN is a highly concentrated germiCidal detergentformulated foruse where broad spectrum disinfection is required in the presence ofmoderate amounts of organic soil. . . .· . -., . . .2/

\ 61(RIGHT PANEL)(HEALTH CARE FACILITY USE)DIRECTIONS FOR USEIt is a violation of federal Law to use thisinconsistent with its labeling.CLEANING AND DISINFECTIONproductinamanner orbroad spectrum disinfection of gram negative and gram positivebacteria, including Pseudomonas aeruginosa, and Mycobacterium tuberculosisadd 1/2 ounce PHENO-CEN to the gallon of water. Remove heavy soil or gross( -tlth then apply solution with a mop, cloth, sponge or mechanical sprayer. as to wet the surface thoroughly. Allow to remain wet for 10 minutesand then let air dry. If higher detergency is desired, increase dilutionto 2 ounces per gallon of water. Prepare a fresh solution for each use.EFFICACY PERFORMANCEThe broad spectrum efficacy of PHENO-CEN has been confirmed using A.O.A.C.protocol testing at a use-dilution of 1:256 in the presence of S bloodserum (used to simulate organic soil load), at 20 degrees Celcius with anexposure time of 10 minutes.GERMICIDAL:PRENO-CEN is effective against the broad spectrum of Gram positive andGram negative pathogens as confirmed against Salmonella choleraesuis,Staphylococcus aureus, and Pseudomonas aeruginosa by the AOAC Use Dilution st,in the presence 9f 5 organic soil load at 20 degrees Celcius with n exposure time of 10 minutes.FUNGICIDAL:At 1/2 ounce per gallon of water, PHENO-CEN is also effective againstTrichophyton mentagrophytes, (the athlete's foot fungus) in use areas suchas shower room floors, locker room benches, bathmats or any other hardnonporous, inanimate environmental surfaces.TUBERCULOCIDAL. . . . .· .PRENO-CEN disinfectant"s effectiveness against Mycobact r1 bovi (BCG)is demonstrated through testing using the AOAC Method "Cnnfirmative inVitro Test for Determining Tuberculocidal Activity" in 10 m:nutes at 20 C . ."'· ·. . ., .2.\

.71.11Page 5VIRUCIDAL·KILLS HIV-1 ON PRE-CLEANED ENVIRONMENTAL SURFACES/OBJECTS PREVIOUSLYSOILED WITH BLOOD/BODY FLUIDS in health care settings or other settings inwhichthereisanexpectedlikelihood of soiling of inanimatesurfaces/objects with blood orbodyfluids.andinwhichthesurfaces/objects likely to be soiled with blood or body fluids can beassociated with the potential for transmission of human immunodeficiencyvirus Type-1 (HIV-1) (associated with AIDS).!ECIAL INSTRUCTIONS FOR CLEANING AND DECONTAMINATION AGAINST HIV-l (AIDSVIRUS) OF SURFACES/OBJECTS SOILED WITH BLOOD/BODY FLUIDS.PERSONAL PROTECTION: Clean-up should always ve done wearing protectivelatex gloves. gowns nasks and eye protection.CLEANING PROCEDURE: Blood and other body fluids must be thoroughly cleanedfrom surfaces and objects before application of the disinfectant.CONTACT TIME: Leave surface wet for 10 minutes with a 1/2 ounce peruse-solution (1:256). Pheno-Cen and water.gallonDISPOSAL OF INFECTIOUS MATERIALS: Blood. body fluids. cleaning materialsand clothing should be autoclaved and disposed according tolocalregulations for infectious waste disposal.PELIGRO:Si\struc ionesno puede leer en ingles. pregunte a su supervisor sobre lasdo uso aprop,iadas antes do trabajar con este producto .·. .· . .· '.

.(MUSHROOM FARM PREMISE USE)GERMICIDAL-DETERGENT WITH ORGANIC SOIL TOLERANCEFORMULATED FOR MUSHROOM FARM SANITATIONPRENO-CEN effectivelyKills fungi and bacteria which prove dangerous to mushroom crops.DO NOT APPLY TO MUSHROOM CROP. DO NOT APPLY TO COMPOST OR CASING.*USE ONLY AS DIRECTED*EFFICACY PERFORMANCE(GERMICIDAL:PHENO-CEN has been tested and found effective against bacteriato the mushroom crop including:Pseudomonas fluorescens (Biotype G) . Bacterial BlotchDiseaseP"eudomonas aeruginosa . . Mummy DiseaseFUNGICIDAL:detrimentalFungi specific to the mushroom industry which PHENO-CEN has been testedagainst and found effective include:Verticilliu fungicola . (Verticillum disease. Brown spotor Fungus spot)Mycogone perniciosa . (Mycogone disease or Wet bubble)Tricoderma viride . (Tricoderma spot. Tricoderma blotch,Tricoderma mildew. Green mold)Dactylium dendroides . (Hypomyces mildew.Cobweb, Soft decay)MUSHROOM FARM INDUSTRY USEGeneral InformationPHENO-CEN is a phosphate free. germiCidal detergent effective in thepresence of moderate amounts of organic soil on a variety of surfacesfound at mushroom farms. PHENO-CEN's tri-phenolic formula is designed forone-stepcleaninganddiSinfectingofhard inanimate non-porousenvironmnetal surfaces. PHENO-CEN is strong enough to kill broadspectrum of microbial mushroom pests. yet mild enough . . ave·nb.harmfuleffects on the surfaces being treated when used as directed . :,Areas of UsePHENO-CEN has been designed for use between crops on surfac s th t . o notcome in contact with the crop. Areas of intended uoe incluae tools.breezeways ana track alleys before spawning, inside and ' u side walls ofmushroom houses, lofts, floors, storage sheds. spawning machine9:' ampers whereand casing rings. Use of PHENO-CEN should be limited to ar,a compost and mushrooms are not present. . :

(MUSHROOM FARM PREMISE USE)DIRECTIONS FOR USEIt is a violation of Federal Law to useinconsistent with its' labeling.SITE PREPARATIONt isproductin a mannerThe first step in anyon-going sanitation program should be the removal ofgross contamination and debris. This may be accomplished using a shovel,broom, or vacuum depending on the area to be disinfected. The efficacy ofeven the most efficient germicidal cleaner is reduced in the presence ofheavy organic matter.CLEANING AND DISINFECTION( or all general cleaning and disinfection, use 1/2 ounce ofPHENO-CEN pergallon of water (1:256 dilution). Apply PHENO-CEN as a spray, wettingsurfaces thoroughly. Treated surfaces should be allowed to remain wet for10 minutes and let air dry. For heavily soiled areas, a precleaning stepis required.Prepare a fresh solution for each use.When greaterdetergent action is desired, dilute PHENO-CEN two ounces of concentrate toeach gallon of water. Heavily soiled areas may require repeated cleaningbefore treatment.Apply PREMO-CENonly on surfaces that DO NOT come in contact with thecrop. USE AS A PREMISES SPRAY, DO NOT APPLY TO THE CROP, COMPOST, ORCASING. Rinse treated surfaces with potable water before they contact thecrop, compost or casing.,· . . .·. " . '.

101 .1-((POULTRY AND SWINE PREMISE USE)Formulated for EffectivePoultry & Swine Premise SanitationDIRECTIONS FOR USEIt is a violation of federal Law to use thisinconsistent with its labeling.SITE PREPARATION(productinamannerThe first step in anyon-going sanitation program should be the removal ofgross contamination and debris. This may be accomplished using a shovel, room,or vacuum depending on the area to be disinfected. The efficacy ofeven the most efficient germicidal cleaner is reduced in the presence ofheavy organic matter. Once the heavy debris is eliminated, disinfectioncan be accomplished in a single step.CLEANING AND DISINFECTIONFor all general cleaning and diSinfection, use 1/2 ounce of PHENO-CEN pergallon of water (1:256 solution). Apply PHENO-CEN using a cloth, mop, orpressure sprayer so as to thoroughly wet surface to be disinfected.Allowto remain wet for 10 minutes and then let air dry. For heavily soiledareas, a precleaning step is required. Prepare a fresh solution for eachuse. .· .". · . ."- " .

1/(POULTRY AND SWINE PREMISE USE)EFFICACY PERFORMANCEThe broad spectrum efficacy of PHENO-CEN has been confirmed using A.O.A.C.protocol testing at a use-dilution ot 1:256 in the presence otbloodserum (used to simulate organic soil load), at 20 degrees Celcius with anexposure time of 10 minutes.5'GERMICIDALPHENO-CEN is effective against the broad3ram negative pathogens including:Staphylococcus aureusPseudomonas aeruginosaSalmonella choleraesuisMycoplasma synoviaeMycoplasma gallisepticumPseudomonas fragispectrumofGrampositiveandEscherichia coliSalmonella puilorumSalmonella gallinarumBordetella aviumPasteurella multocidaFUNGICIDALPHENO-CEN's fungicidal efficacy has been confirmed through testing usingthe AOAC Fungicidal Test against the pathogenic tungi, Trichophytonmentagrophytes and Aspergillus fumigatus·VIRUCIDALVirucidal testing using prescribed E.P.A. testing procedures has verifiedPHENO-CEN's ociated with poultry and swine areas including:Avian Influenza VirusAvian Herpes Virus 2 (Mareks Disease)Avian Bronchitis VirusHog Cholera VirusAvian Laryngotracheitis VirusPseudorabies VirusAvian AdenovirusAfrican Swine Fever VirusAvian Reovirus. .-· . .· . ----------------------------------

(POULTRY AND SWINE PREMISE USE)AREAS OF USEPOULTRY PREM!SE SANITATION-Egg Receiving Area-Egg Holding Area-Setter Room-Hatchery Room-Poultry Buildings-Tray Dumping Area-Chick Processing Area-Chick Holding Room or Area-Chick Loading Area-Hauling EquipmentAPPLICATION AND USE DILUTIONSPOULTRY HOUS"S:1.Remove all poultry and feeds from premises. trucks. coops. and crates.Remove all liter and droppings from floors, walls and surfaces offacilities occupied or traversed by poultry. Empty all troughs, racks.and other feeding and watering appliances. Thoroughly clean all surfaceswith soap or detergent and rinsewith water.2.Use 1/2 ounce of PHENO-CEN per gallon of water. Saturate surfaceswith the recommended disinfecting solution for a period of 10 minutes.Ventilate buildings. coops. and other closed spaces. Do not house poultryor employ equipment until treatment has bee absorbed. set or dried.Thorougly scrub treated feed racks. troughs. automatic feeders. fountainsand waterers with soap or detergent. and inse with potable water beforereuse.HATCHERIES:1.Use 1/2ounce of PHENO-CEN per gallon of water to treat hatchers.,etters. trays. racks. carts. sexing tables. delivery trucks an otherhard surfaces.Leave all treated surfaces exposed to iisil.fectantsolution for 10 minutes or more.EQUIPMENT:1. Empty all troughs. racks. feeding and watering bins, buckets andfountains.2.Use 1/2ounce of PHENO-CENper gallon of water to treat allequipment. Leave all treated surfaces exposed to disinfectant solutionfor 10 minutes or more. . . ,VEHICLES:,1.Clean all vehicles including mats. crates. cabs and wHeels with highpressure water and PHENO-CEN disinfectant Use 1/2ounce' 'ter gallon ofwater to treat all vehicles.Leave all treated sur!aces·exposed todisinfectant solution for 10 minutes or more. .'SHOEBATHS:.' ,.1. Shoebath containing one inch of freshly made disinfectant"'solution should be placed at all entrances to buildings and hatcheries. 'xftp,pgethedisinfectant solution in the bath daily or when solution appears dirty.

1:S'1).}(POULTRY AND SWINE PREMISE USE)POULTRY AND ANIMAL INDUSTRY USEFOR CLEANING AND DISINFECTION OF:EQUIPMENT including feeders, waterers, fans, racks,troughs, bins andbuckets.VEHICLES including live haul poultry delivery trucks, feed trucks, serviceperson cars, tractors and all other vehicles.HATCHERIES including floors, walls, equipment, incubators, hatchers, trayand buggies.SHOE BATHS including all entrances to buildings and hatcheries.AREAS OF USESWINE AND CATTLE SANITATION-Farrowing Barns and Areas-Blocks-Creep Area-Waterer & Feeder-Nursery-Hauling EquipmentMISCELLANEOUS-Horse Stables-Dressing Plants-Sick Pens-Cat and Dog KennelsGeneralDisinfectionUses:Ca -Sales Barn Stalls-Chutes/Loading Equipment-Veterinary Hospitalsbe used in theroutir. disi fectionof hog.ouses, farrowing houses,' finishing houses, growers,feeders and otherequipment; horse stables and sick pens at race tracks or sale barns,hospital pens, calf pens and equipment.Disinfecting houses used forpoultry, turkeys, ducks and game birds and for equipment used in t ooding,growing and laying quarters. Disinfecting dog and cat kennels as well ,researchlaboratories and medical institutions.Spraying cattle pens, chutes,loading equipment trucks and animal manure pits for the control of odorand ammonia.Dressing Plant Use:, .Disinfect equipment, utensils. walls and floors in po'.1I-:ry and animaldressing plants.Equipment and utensils must be thoroughly rinsed withpotable water before operations are resumed. Disinfe t offal rooms,exterior walls and loading platforms of dressing plants.·.· . - . " .

.'(POULTRY, SWINE AND FARM USE)APPLICATION AND USE DILUTIONSFARM PREMISE:DO NOT USE IN MILKING STALLS, MILKING PARLORS OR MILK HOUSES.1.Remove all animals and feed from premises, vehicles and enclosures.Remove all litter and manure from floors, walls and surfa es of barns,pens, stalls, chutes, and other facilities and fixtures occupied ortraversed by animals. Empty all troughs, racks and other feeding andwatering appliances. Thoroughly clean all surfaces with soap or detergentand rinse with watpr.2. Use 1/2 ounce of PHENO-CEN per gallon of water (1/2part PHENO-CEN to256 parts of water). Saturate all surfaces with the recommended solution( or a period of 10 minutes.3. Use 25-50 gallons of disinfectant solution per 1000 square feet offloor space.Totally immerse equipment to be treated in disinfectantsolution. Ventilate building and other closed spaces.Do not houselivestock or employ equipment until treatment has been absorbed, set ordried. Thoroughlyy scrub all treated feed racks, troughs, automaticfeeders, fountains, and waterers with soap or detergent and rinse withpotable water b fore reuse.EQUIPMENT:1. Empty all troughs, racks, feeding and watering bins, buckets andfountains.2.Use 1/2 ounce of PHENO-CEN per gallon of water (1/2part PHENO-CEN to256 parts of water) to saturate all equipment. Leave all treated surfacesexposed to disinfectant solution for 10 minutes or more.-'EHICLES:Clean all vehicles including mats, crates, cabs and wheels with high\pressure water and PHENO-CEN solution.2. Use 1/2 ounce of PHENO-CEN per gallon of water (1/2part PHENO-CEN to256 parts of water) to treat all vehicles. Leave all treated surfacesexposed to disinfectant solution for 10 minutes or more.HATCHERIES:1. Treat all surfaces thoroughly with PHENO-CEN solution by scrubbingwith brush under high water pressure with emphasis on cracks and mouldingwhere fungus and mold are usually located.2.Use 1/2 nce ofPHENO-CEN per gallun of water (1/2part PHENO-CEN to 256 p9r 9 of.water) totre&t hatchers, setters, trays, racks, carts, sexing: tn les, Aeliverytrucks and other hard surfaces.Leave all treated surfaces exposed todisinfectant solution for 10 minutes or more.SHOEBATHS SANITIZER: 1. Shoebath containing one inch r fresn y madedisinfectant solution should be placed at all entrances· , ;) builaings andhatcheries. Change the disinfectant solution in the bath daily .·b whensolution appears dirty. . .,

Is. \\-. "age(OPTIONAL SWINE AND POULTRY PREMISE,p. te! \ .' " l\ ' vLawtouse13 j DIRECTIONS FOR USEIt is a violation of Federalinconsistent with its labeling.'I1 ).(ttisproductin a mannerSWINE AND POULTRY BUILDINGS,HATCHERIES, DRESSING PLANTSThe first step in any sanitation program should be to remove grosscontaminationand debris. The efficacy of even the most efficientgermicide/ cleaner is reduced in the presence of heavy organiC matter. emoveall animals, poultry, and feeds from buildings, vehicles and( closures. Empty all troughs, racks and other feeding and wateringeqUipment. Mix PHENO-CEN at the rate of 1/2 ounce per gallon of water(1:256) and satutate all surfaces for 10 minutes. Use 25-50 gallons ofdisinfectant solution per 1000 square feet of floor space. Ventilatebuildings and other closed spaces. Do not house livestock or poultry oruse eqUipment until treatment bas been absorbed set or dried. Rinseequipment with potable water before reuse. Thoroughly scrub all treatedfeed racks, troughs, automatic feeders, fountains and waterers with soapcr detergent and rinse with water before reuse.In poultry and animal dressing plants, disinfect equipment, utensils,interior and exterior walls, floors, offal and loading platforms withPHENO-CEN at the 1:256 dilution rate. Again, equipment and utensils mustbe thoroughly rinsed with potable water before reuse.Equipment .mpty all troughs, racks and other feeding and watering appliances.Thoroughly clean all surfaces with soap or detergent and rinse with water.Mix 1/2 ounce of PHENO-CEN Disinfectant per gallon of water (1:256) andtreat all equipment for 10 minutes or more. Thoroughly scrub treatedfeeding and watering appliances with soap or detergent and rinse withpotable water before reuse. Clean all vehicles including mats, crates,cabs and wheels with high pressure water and PHENO-CEN (1:256 dilution).Leave all treated surfaces exposed to disinfectant solution for 10 minutesor more.,. . ." ··.

Ib1Page HSANITIZING LIVESTOCK BUILDINGS USING FOGGINGDO NOT USE IN MILKING STALLS, MILKING PARLORS, OR MILK HOUSES.Remove all animals and feed from premises, vehicles, and enclosures.Remove all litter and manure from floors, walls and surfaces of barns,pens, stalls, chutes, and other facilities and fixtures occupied ortraversed by animals. Empty all troughs, racks, and other feeding andwatering appliances. Thoroughly clean all surfaces with soap or detergentand rinse with water. Inspect to be sure that allpeople, poultry,livestock and pets have left the building. Close all openings; windows,doors, louvres, curtains, etc. Be sure all exhaust fans are turned off. ixone part Pheno-Cen w!th two parts water in the reservoir of the( ogger. With the setting on maximum output, fog the treatment into thearea to be sanitized. Use a total of 1 gallon of Pheno-Cen for each6000-8000 square feet of floor area. In multi-story buildings, theapplication must be repeated for each floor that is to be sanitized.When fogging is completed, ventilate buildings, and other closed spaces.Do not house livestock or employ equipment until treatment has beenabsorbed,or dried. Thoroughly scrub all treated feed racks, mangers,troughs, automatic feeders, fountains and waterers with soap or detergent,and rinse with potable water before reuse.NOTE: The fog generated is irritating to the eyes, skin and mucousmembranes. Under no circumstances should a room or building be entered byanyone within two hours of the actual fogging. If the building must beentered, then the individuals entering the building must wear a selfcontained respirator approved by NIOSH/MSHA, goggles, long sleeves andlong pants.t oggingis to be used' as an adjunct to acceptable manual cleaning anddisinfecting of room and machine surfaces. .

.'111 ).ofPage 15 S ITIZINGHATCHERY ROOMS USING FOGGING DEVICESReaove all anim.ls and feed froa premises, vehicles, and enclosures.Re ove alllitter and manure from floors, w8.11s and surfaces at tne roomto be treated. Empty all troughs, racks and other feeding and wateringappliances.Thoroughly clean all surfaces with soap or detergent andrinse with water. Close room off so fog is confined to room to betreated. Mix one part Pheno-Cen to five parts water. (1/2 gallon Pheno-Cento 2.5 gallons of water.) Insert the nozzle of the fogger through asuitable opening into the room. With the setting in maximum output, torone minute for each .000 cubic feet of space in the room. When fogging iscompleted, ventilate buildings, and other closed spaces. Do not houselivestock or employ equipment until treatment has been absorbed,or dried. horoughlyscrub all treated feed racks, mangers, troughs, automaticeeders, fountains and waterers with soap or detergent, and rinse withpotable water before reuse.SANITIZING INCUBATORS AND HATCHERS USING FOGGING DEVICESMix 6 ounces Pheno-Cen to 122 ounces water. Fog 3-8 ounces 0: this intosetters and hatchers immediately after transfer. Repeat daily in settersand every]2 hours in hatchers. Discontinue ha cher treatments at least 2.hours prior to pulling the hatch. Do not allow people to contact orbreathe this fog and do not enter until the fog has settled (30-60 minutesafter logging is completed). It is acceptable to fog setters and hatcherswith a 1/2 ounce per gallon solution of Pheno-Cen on an hourly or everyother hour basis. If this is done, fog for 30-90 seconds once per hour oronce every two hours. When fogging is completed, ventilate buildings, andother closed spaces. Do not house livestock or employ equipment untiltreatment has been absorbed,or dried. Thoroughly scrub all treated feedracks. mangers, troughS, automatic feeders.fountains and waterers with'oap or detergent, and rinsewith potable water before reuse.,NOTE: The fog generated is irritating to the eyes, skin and mucousaembranes. Under no circumstances should a room r building be entered byanyone within two hours of the actual fogging. If the building must beentered, then the individuals entering the uilding must wear a selfcontained respirator approved by NIOSH/MSH . goggles, long sleeves andlong pants.Fogging is to be used as an adjunct to acceptabledisinfecting of room and machine surfaces.manual· .cleaning , . . . . . end

,8"·' CIJ#''t.,.1'J.\. u-'. - page 16 9";: .w.- \i\ " ,(AQUACULTURE USE)Germicidal-Detergent FormulatedFor Disinfecting Tools, Equipment,t1 ll,and Surfaces in Greenhouses, Micropropagation;Laboratories, Aquaculture and Hydroponic ParasFacilities, or PlantsWARNING!! !··MUST NOT COME IN CONTACT WITH EDIBLE CROPS··INFORMATION:PHENO-CEN disinfectant is a phosphate free, germir.idal detergent effectivein the presence of moderate amounts of organic soil on a variety ofsurfaces found in greenhouses, micropropagation laboratories. aquacultureand hydroponic farms. PHENO-CEN's multisynthetic phenolic formula is esigned for one-step cleaning and disinfecting hard inanimate nonporousurfaces.PHENO-CEN is strong enough to kill a broad spectrum of plantp thogens and pests, yet mild enough tohave no harmful effects on thesurfaces being treated when used as directed.G ERALARE.\S OF USE:PHENO-CEN is designed to be used between crops, or between daily workprocedures on surfaces, to ls and equipment that do not come in contactwith edible crops. Areas or :ntended use include tr !s, floors, walls,bench tops, potting areas, headhouses, dry stora e areas, sheds. barns,automated potting equipment, cultivating and planting equipment. pruningand budding equipment, pallets and pallet moving equipment.DO NOT APPLY TO CROP, SOIL OR GROWING EDIA IN WHICH A CROP GROWS OR WILLBE GROWN!To assure compliance, rinse -eated surfaces and tools withpotable water before they contact the cro or the substrate in which thecrop is or will be growing.DIRECTIONS FOR USEIt is a violation of Federal Law to use this product in a mannerinconsistent with its' labeling.SITE PREPARATIONThe first step in anyon-going sanitation program should be the removal ofgross co tamination and debris. This may be accomplished using a shovel,broom, or vacuum depending on the area to be disinfected. The efficacy ofeven the most efficient germicidal cleaner is reduced in the presence ofheavy organic matter. Onc the heavy debris is eliminated, disin er. joncan be accomplished in n single step. . .CLEANING AND DISINFECTIONFor all general cleaning and disinfection, use 1/2 ounce CJfPHE O-.CEN pergallon of water (1:256 solution). Apply PHENO-CEN using a ) th, " r; orpressure sprayer so as to thoroughly wet surface to be disinfected.Allowto remain wet for 10 ninutes and then let air dry.For heavily oi!edareas, a precleaning step is required.Prepare a fresh solutior'f l' eachuse. .:

"I '11-Page ni(AQUACULTURE USE)EFFICACY PERFORMANCEThe broad spectrum efficacy of PHENO-CEN has been confirmed using A.O.A.C.protocol testing at a use-dilution of 1:256 in the presence of 5 bloodserum (used to simulate organic soil load), at 20 degrees Celcius with anexposure time of 10 minutes.GERMICIDALPHENO-CEN has been tested and is effective against bacteria recognized asdetrimental to a variety of crops grown in controlled environments.Bacterial plant pathogens found susceptible to the killing power ofPHENO-CEN include:(Pseudomonas solanacearum . Southern Bacterial WiltPseudomonas cichorii . Bacterial Leaf Spot and BlightErwinia caratovora . Soft RotErwinia chrysanthemi . Soft Rot, Leaf Spot, Bacterial BlightAgrobacterium tumifaciens . Crown GallXanthomonas pelargoni . Bacterial BlightXanthomonas campestria . Stem Rot, Leaf Spot. Bacterial B

DATC · . ' UNITED STATES ENVIRONMENTAL PROTECTION AGENCY Olivia D. Laird, Agent for Central Solutions, Inc. 3130 Brinkerhoff Road P.O. Box 15276 . Antiaicrobial Program Branch Registration Division (7505e) C!!:NTER PANEL') (REQUIRED). PHENO-CEN Germicidal/Detergent With Organic Soil Tolerance