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Andrew S. Weyrich, PhDCURRICULUM VITAEI.PERSONAL INFORMATIONName:Birthplace:Citizenship:Academic 995III.Andrew Scott Weyrich, Ph.D.Dayton, OHUSAVice President for ResearchPresident, University of Utah Research FoundationProfessor of Internal MedicineH.A. & Edna Benning Presidential Endowed ChairUniversity of Utah201 Presidents Circle, Room 210Salt Lake City, UT 84112-9011Phone: 801-581-3002andy.weyrich@utah.eduDegreeBS, BiologyInstitutionBaldwin-Wallace College,Berea, OHMS, Health & Exercise ScienceWake Forest University,Winston-Salem, NCPhD, Physiology/Pharmacology Bowman Gray School of Medicine,Winston-Salem, NCPost-doctoral fellowThomas Jefferson University,Philadelphia, PAPost-doctoral fellowUniversity of Utah,Salt Lake City, UTPROFESSIONAL POSITION(S)Current:2016-present Vice President for Research, University of Utah2016-present President, University of Utah Research Foundation2007-present Tenured Professor, Department of Internal Medicine, University of Utah2015-present H.A. & Edna Benning Presidential Endowed Chair, University of UtahMarch, 20211
Andrew S. Weyrich, PhDPrevious:IV.2017-2018Interim Director, Molecular Medicine Program, University of Utah2017Interim Associate Vice President for Research at Health Sciences,University of Utah2013-2016Associate Dean for Research, Health SciencesUniversity of Utah2012-2015Attilio D. Renzetti Jr. Presidential Endowed Chair, Division ofRespiratory, Critical Care, and Occupational Pulmonary Medicine,University of Utah2002-2007Associate Professor, Department of Internal Medicine, University of Utah1995-2002Assistant Professor, Department of Internal Medicine, University of UtahHONORS AND ACHIEVEMENTS198419841984, 19851985198519861987, 19881990199720032004Honorable Mention NCAA Academic All AmericanOmicron Delta Kappa Honorary SocietyLee Tressel Academic/Athletic ScholarshipNCAA Academic All AmericanCum Laude GraduateCertified, ACSM Exercise Test TechnologistGraduate Assistantship, Bowman Gray School of MedicineACSM Exercise Test Technologist Testing SupervisorYoung Investigator Prize in Thrombosis, American Heart AssociationEstablished Investigator, American Heart AssociationThe Children’s Health Research Center, University of Utah, OutstandingMentorship2011Investigator Recognition Award, XXIII Congress of the InternationalSociety on Thrombosis and Haemostasis, Kyoto, Japan2011Special Recognition Award in Thrombosis, American Heart Association’sCouncil on Arteriosclerosis, Thrombosis and Vascular Biology2012Chair, American Society of Hematology Scientific Committee on Platelets2013William Dameshek Award, American Society of Hematology2014Chair, Gordon Research Conference on Hemostasis2017Scientific Program Co-Chair, American Society of Hematology2018-present NIH/NHLBI Advisory Council2020John R. Hoidal, MD, Senior Investigator Award, University of UtahMarch, 20212
Andrew S. Weyrich, PhDV.TEACHING AND MENTORING EXPERIENCETeaching:1985 - 1987Exercise Science, undergraduate students, Wake ForestUniversity1996 – 2010Gross Anatomy, Unit I and II, 1st year medical students,University of Utah2005 –2012Gene Expression, 1st and 2nd year graduate students,University of UtahTraineeDatesPositionCurrent PositionJulie Kessel, MD1994-1998FellowAssistant Professor ofPediatrics,University of WisconsinJeanne Falk, MD1996-1998Research AssociateOBGYN,Intermountain Budge ClinicRavinder Pabla, PhD1996-1998FellowScientist, Essex, U.K.Tracy Mahoney, PhD1997-2000FellowScientific WriterSpencer Galt, MD1997-2002SurgeonProfessor of Surgery,Intermountain MedicalCenter, UTRob Christensen, MD1999-2000MD StudentFamily Practice, McKay-DeeHospitalStephan s Universität,Tübingen, GermanyCarolyn Fratto2000-2002Undergrad StudentPediatric Nurse,Sheltering Arms Children andFamily Services, NYCon Yost, MD2000-2010FellowAssociate Professor ofPediatrics,University of UtahMelvin Denis, PhD2002-2004MD/PhD StudentDeceasedEliott Spencer, PhD2002-2004FellowDirector, Utah Cord BankJason Foulks, PhD2002-2008Post-doc FellowSenior DirectorSDP Oncology, Lehi, UTMarch, 20213
Andrew S. Weyrich, PhDMark Martinez, MD2002-2010FellowPulmonary and CriticalMedicine, SLC, UtahFrederick Rubner, MD 2003-2005FellowNeonatologist, Aurora BayMedical Center, WisconsinBen Risenmay, MDUndergrad StudentAnesthesiologist, IntermountainHealthcare, UtahHansjörg Schwertz, MD 2004-2008Post-doc FellowFamily and PreventiveMedicine, Molecular Medicine,University of UtahEmilysa Tolley2004-2008Undergrad StudentLab Services Rep, ScrippsHealthNoemi Michetti2006-2009Graduate StudentTransfusion Medicine,Azienda USL di Pescara,Dipartimento di MedicinaTrasfusionaleNathan Thornton, MD 2006-2009Clinical FellowMatthew Rondina, MD 2006-2010Chief ResidentNeonatalogist,St. Luke's Children's Hospital,Boise, IdahoAssociate Professor,Director, Molecular MedicineUniversity of UtahHeather Campbell, MD 2008-2010Clinical FellowAssistant Professor, OBGYN,University of UtahJesse Rowley, PhD2008-2011Post-doc FellowAssistant Professor,University of UtahBjoern Kraemer, MD2009-2010Clinical FellowClinical Fellow, EberhardKarls Universität, Tübingen,GermanyZechariah Franks, MD2009-2013Post-baccalaureateOtolaryngology Resident,Johns Hopkins, MDTammy Smith,MD/PhD2009-2014Graduate StudentNeurologist, University of UtahHospital and ClinicsJack Staddon, MD2012-2014Clinical FellowPediatric Hematology,Billings ClinicPatrick ZimmermanDO2010-2013Post-baccalaureateSurgery Fellow,University of VermontMatthew Smith,MD/PhD2010-2013MD/PhD StudentAssistant Professor,University of Washington2004-2006March, 20214
Andrew S. Weyrich, PhDSebastian Schubert,PhD2011-2013Post-doc FellowPost-doc Fellow, Mainz,GermanyTagrid Ruiz, MD2013MD StudentOBGYN Resident,University of UtahDallas Shi, MD/PhD2012-2014MD/PhD StudentOccupational MedicineResident, University of UtahMcKenzie CarlislePhD2012-2015Post-doc FellowResearch Program Manager,Biofire DiagnosticsDanielle Nance, MD2013-2015Clinical FellowAssistant Professor,University of ArizonaRobert Campbell, PhD 2009-2014Post-doc FellowInstructor, University of UtahAdrianaVieira-de-Abreu, PhD2010- 2014Post-doc FellowIACUC Research Manager,University of UtahClaudia Araújo, PhD2011-2016Post-Doctoral FellowResearch Manager,University of UtahSeth Ack2016 &2017High School InternUndergraduate Student,University of Puget SoundCameron Galt2014-2015Undergrad StudentSki Patrol and Guide,Utah and Intermountain WestKrystin Kraul, PhD2016-2019Post-doc FellowPost-doc, GermanyElizabeth MiddletonMD2017-2019Clinical FellowAssistant Professor,University of UtahAlicia Eustes, PhD2015-2020PhD StudentPost-doc, University of IowaBannu Manne, PhD2016-presentPost-doc FellowPost-doc, University of UtahAmily Guo, PhD2017-presentPost-doc FellowPost-doc, University of UtahDonald LynchMD2019-presentPRIDE ScholarAssistant Professor,University of CincinnatiMerry Joseph2020-presentUndergrad StudentPresidential Intern,University of UtahAlejandro Sanchez2021-presentUndergrad StudentPresidential Intern,University of UtahMarch, 20215
Andrew S. Weyrich, PhDVI.MEMBERSHIP/AFFILIATION IN PROFESSIONAL SOCIETIES AND COMMUNITYPARTNERSHIPSAmerican Heart Association (AHA)American Society of Hematology (ASH)Association of American Universities (AAU)Association of American Medical Colleges (AAMC)Association of Public and Land Grant Universities (APLU)Canine Companions for Independence (CCI)Crimson Club, University of UtahNational Abilities Center (NAC)U-FITUniversity Neighborhood Partners (UNP)Utah Parent CenterVII.ADVISORY BOARDS AND 15-20162016-2017Member, Retention, Promotion, and Tenure (RPT) CommitteeMember, School of Medicine (SOM) Space Task ForceManager, Health Sciences (HSC) Research SpaceCo-Chair, HSC Research Advisory CommitteeMember, VPR Limited Submissions Advisory CommitteeDirector, HSC Cores and Recharge CentersChair, SOM Bridge Funding Advisory CommitteeChair, USTAR Space Working GroupMember, VPR Research Instrumentation Fund Review CommitteeMember, Medical Education Building (MED) Complex Working GroupMember, University of Utah Transformative Excellence ProposalCommitteeDirector, HSC T-based Training Grant Support OfficeMember, SOM Search Committee, AnesthesiologyDepartment ChairMember, VPR Search Committee for Office of Comparative MedicineDirectorSOM Liason, Undergraduate Research Opportunities Program (UROP)SOM Liason, Biology Undergraduate Research Progrom (BioURP)Member, Internal Medicine Search Committee, Harrison Chair inDivision of RheumatologyMember, Internal Medicine Search Committee, Renzetti Chair inDivision of Respiratory and Clinical CareMember, College of Nursing Search Committee, Associate Dean forResearch in College of NursingMarch, 20216
Andrew S. Weyrich, ber, Graduate Student Support/Tuition Benefits CommitteeUniversity of Utah Asia Campus, Board of DirectorsCCTS (Clinical Center for Translational Sciences) Advisory CommitteeCo-chair, Search Committee for Senior Vice President of HSC, CEO ofUniversity of Utah Health, and Dean of the SOMChair, Facilities and Administration Task ForceHCI (Huntsman Cancer Institute) Advisory CommitteeCampus Budget Advisory CommitteePresidential Budgetary Review CommitteeAssociation of American Universities (AAU) Senior Research OfficerCo-chair, Foreign Influence Task ForceAcademic Senate, Post-doctoral Policy CommitteeCardiovascular Strategy Steering CommitteeAAU Core Senior Research Officer Steering CommitteeRESEARCH TALKS AND SERVICEInvited Lectureships and Keynote iversity of Utah, CVRTI, Salt Lake City, UTAmerican Heart Association, Orlando, FLJohannes-Gutenberg University, Mainz, GermanyMartin-Luther University, Halle, GermanyRoyal College of Surgeons, Dublin, IrelandEuropean Society of Cardiology, Vienna, AustriaEuropean Stroke Conference, Valencia, SpainMartin-Luther University, Halle, GermanyWorld Stroke Congress, Vancouver, CanadaLeading Stroke Experts Workshop, Montreal, CanadaInternational Society of Thrombosis and Hemostasis, Platelet PhysiologySymposium, Plenary Speaker, Sydney, AustraliaBoston University School of Medicine, Boston, MACleveland Clinic, Cleveland, OHEmory University, Atlanta, GAGordon Conference on Hemostasis, Waterville, MEUniversity of North Carolina, Chapel Hill, NCPortola Pharmaceuticals, San Francisco, CAOklahoma Research Medical Foundation, Oklahoma City, OKPlatelet International Symposium, Ma'ale Ha'chamisha, IsraelSymposium on Sepsis, Rio de Janeiro, BrazilAmerican Society of Hematology, Plenary Speaker, Orlando, FLLerner’s Research Institute, Cleveland, OHMarch, 20217
Andrew S. Weyrich, 0092009201020102010201020102010201020102010Gordon Conference on the Cell Biology of Megakaryocytes and Platelets,Ventura, CAResearch Initiatives in Vascular Disease Conference, Washington D. C.Blood Center of Wisconsin, Milwaukee, WIFASEB Summer Research Conference on Proteases in Hemostasis and VascularBiologyUniversity of North Carolina, Chapel Hill, NCGrand Rounds, University of Utah, Salt Lake City, UTPuget Blood Center, Seattle, WAUniversity of British Columbia, Vancouver, British ColumbiaJohns Hopkins University, Baltimore, MDPulmonary Research Conference, University of Utah, Salt Lake City, UT4th Symposium on Hemostasis, University of North Carolina, Chapel Hill, NCArteriosclerosis, Thrombosis and Vascular Biology, Plenary Session, Atlanta,GAUniversity of Calgary, Calgary, CanadaAABB (American Association of Blood Banks), Montreal, CanadaChildren’s Hospital of Pennsylvania (CHOP), Philadelphia, PAPlatelet International Symposium, Woods Hole, MAAmerican Society of Hematology, Plenary Speaker, San Francisco, CA4th Annual Platelet Colloquium, Washington D.C.Cell Communication in Health and Disease Workshop, Vienna, AustriaFASEB Hemostasis, Carefree, AZCytopenias and Hemostasis, Orlando, FLHemostasis and Thrombosis Working Group, Washington D.C.Sickle Cell Disease Working Group, Washington, D.C.International Conference on Platelet and Platelet-Leukocyte Interaction Appliedto Infectious Diseases, Rio de Janeiro, BrazilURMC, Rochester, NYThe Paul Imbach Innovator Lecture, American Society of Hematology ITPMeeting, New Orleans, LAHarvard University, Boston, MAThe Hospital for Sick Children, Toronto, CanadaESH International Conference on Immune Thrombocytopenia, Lisbon,PortugalWestern Thrombosis Symposium, University of Utah, Salt Lake City, UTInnate Inflammation Conference, New York, NYPlatelet International Symposium, Tel Aviv, IsraelGordon Research Conference on Hemostasis, Waterville Valley, NHBioscience Symposium, University of Utah, Salt Lake City, UTXIth European Symposium on Platelet and Granulocyte Immunobiology,Beaune, FranceMarch, 20218
Andrew S. Weyrich, ity Medical School of Saint-Etienne, FranceWhitaker Cardiovascular Institute, Boston University School of Medicine,Boston, MACardiovascular, Hypertension & Diabetes Symposium, University of Utah, SaltLake City, UTUniversity of Pittsburgh School of Medicine, Pittsburgh, PAUniversity of Delaware Department of Biological Sciences, Newark, DEHematology Faculty Conference, University of Utah School of Medicine, SaltLake City, UTHuman Medical Genetics Program, University of Colorado, Denver, COSanquin Research, Amsterdam, NetherlandsTransfusion Medicine Research Session, Dutch Blood Transfusion SocietySymposium, Ede, NetherlandsChildren’s Hospital Boston/Dana-Farber Cancer Institute, Boston, MAXXIII Congress of the International Society of Thrombosis and Hemostatis,Kyoto, JapanAso International Meeting, Kumamoto, JapanMetabolism Interest Group, University of Utah, Salt Lake City, UTBritish Society for Haemostasis & Thrombosis Annual Scientific and GeneralMeeting, Brighton, EnglandAABB Annual Meeting &CTTXPO, San Diego, CACanadian Society of Atherosclerosis, Thrombosis and Vascular BiologySymposium, Vancouver, CanadaUniversity of British Columbia Centre for Blood Research, Vancouver, CanadaPuget Blood Center, Seattle, WAOregon Health & Science University, Portland, ORX-gen Congress and Expo, San Diego, CACardiza Foundation Seminar, Thomas Jefferson University, Philadelphia, PAUniversity of Toledo, OHSol Sherry Lecture Series, Temple University, Philadelphia, PAAnnual ASHPO Meeting, New Orleans, LAPlatelet International Symposium, Boston, MA32nd International Congress of the ISBT, Cancun, MexicoBiennial Meeting of the Inflammation Research Association, Bolton Landing, NYInstitute of Biomembranes Conference, Utrecht, NetherlandsPlatelet International Symposium, Tuebingen, GermanyTerumo BCT, Lakewood, COAnnual Meeting of Thrombosis and Haemostasis Research, Munich, GermanyATVB Scientific Sessions, Orlando, FLAABB Annual Meeting & CTTXPO, Denver, COUniversity of Vermont Biochemistry Seminar Series9th Annual Platelet Colloquium, Washington DCMarch, 20219
Andrew S. Weyrich, 0172018201820192020Keystone Symposium on New Frontiers in the Discovery and Treatment ofThrombosis, Keynote Speaker, Keystone, COPlatelets 2014, Ma’ale Hachamisha, IsraelThrombosis and Hemostasis Summit of North America, Chicago, ILUniversity of Kentucky Cardiovascular Seminar Series, Lexington, KYUNC Symposium on Hemostasis, Chapel Hill, NCWashington University Center for Translational Therapies in Thrombosis, St.Louis, MOMidwest Platelet Conference, Chicago, ILDistinguished Lecturer in Immunology, Cincinnati Children’s Hospital, OHAABB Annual Meeting, Philadelphia, PA43rd Annual Philadelphia Workshop in Hemostasis, Thrombosis, andAtherosclerosis Keynote Speaker, Temple University, Philadelphia, PAAmerican Society of Hematology Annual Meeting, San Francisco, CANorthwestern University Grand Rounds, Chicago, ILUniversity of Michigan Frontiers in Science Seminar Series, Ann Arbor, MI,Plenary Speaker, XXV Congress of the ISTH, Toronto, Canada,Grand Rounds, Northwestern University, Chicago, ILState-of-the-Art Lecture, Congress of the International Society on Thrombosisand Haemostasis, Toronto, Canada23rd IUBMB Congress, Foz do Iguaçu, BrazilSeminars in Clinical Research, Rockefeller University, New York, NYOklahoma Medical Research Foundation, Oklahoma City, OKSeminar Chair and Lecturer, 60th Annual Meeting of the GTH,Münster, GermanyNHLBI LncRNA Workshop, Bethesda, MDScientific Advisory Board (SAB) Meeting and Advisory Board Meeting,Rochester, NYNHLBI, NIH Basic & Clinical RFA Grantee Meeting, Bethesda, MDTRC/THD Annual 2016 Face to Face Meeting, Rockville, MDGRC, Cell Biology of Megakaryocytes and Platelets, Keynote Presenter,Renaissance Tuscany II Ciocco, ItalyKeenan Research Centre, Toronto, CanadaBlood Center of Wisconsin, Milwaukee, WINHLBI Biomedicine Lecture, Bethesda, MDKeynote Address, Pittsburgh Hematology Research Symposium, Pittsburgh, PAPeer Review Activities: Regular participation in peer-review activities, including:Foundations and Federal Agencies:1998-2001Research and Development Committee, V.A., University of Utah2002-2005American Heart Association, Western AffiliateMarch, 202110
Andrew S. Weyrich, 4Oklahoma Center for the Advancement of Science and TechnologyAmerican Heart Association, NationalCanadian Institute of Health ResearchNational Institutes of Health, Ad-HocNational Institutes of Health, Thrombosis and Hemostasis Study Section,member2014-2017National Institutes of Health, NHLBI T32 Study Section,member2018-present National Institutes of Health, NHLBI Advisory Council, memberJournals:Associate Editor:Blood Advances (current)Section Editor:Thrombosis and Haemostasis (past)Editorial Board:BloodReferee:Arteriosclerosis, Thrombosis, and Vascular BiologyBloodCell Host & MicrobeCirculationCirculation ResearchJournal of Cell BiologyJournal of Clinical InvestigationJournal of Experimental MedicineJournal of ImmunologyJournal of Pharmacology and Experimental TherapeuticsJournal of Thrombosis and HemostasisNatureNature CommunicationsNature GeneticsNature MedicineNature Structural and Molecular BiologyProceedings of the National Academy of Sciences, USAScienceScience Translation and MedicineOthersMarch, 202111
Andrew S. Weyrich, PhDIX.RESEARCH GRANTSCurrent:07/01/2014 to 06/30/20262T35HL007744-21A1 (A.S. Weyrich, Co-PI)NIH/NHLBIShort-Term Institutional Research Training Grant(Parent T35)07/01/1994 to 6/30/2022T32HL007576 (A.S. Weyrich, Co-PI)NIH/NHLBI“Training in Cardiovascular Research”(Parent T32)07/01/2018 – 06/30/20221R01 HL142804 (A.S. Weyrich, Co-PI)NIH/NHLBI“Translational Control of Megakaryocyte and PlateletFunction in Sepsis”07/01/2018 – 06/30/20231R61/R33 HL141783 (A.S. Weyrich, Co-PI)NIH/NHLBI“OPA1: An Estrogen-Mediated Modulator of PlateletHyperactivation”01/01/2019 – 12/31/20251R35 HL12568306 (A.S. Weyrich, PI)NIH/NHLBI“Translational Control of Megakaryocyte and PlateletGene Expression in Disease”Past:1991-1993NHBLI/NRSA (A.S. Weyrich, PI)“Adhesion Molecules in Ischemia-Reperfusion”1996-1997AHA/GIA (A.S. Weyrich, PI)“Platelet Regulation of Monokine Synthesis”1996-1997PCMC (A.S. Weyrich, PI)“Developmental Expression of Endothelial Cell Adhesion Molecules”1997-2001R29 HL56713 (A.S. Weyrich, PI)NIH/NHLBI“Platelet Regulation of Monokine Synthesis”2000-2001Pfizer (A.S. Weyrich, PI)“Regulation of Interleukin-1 Formation by Platelets”March, 202112
Andrew S. Weyrich, PhD2001-2014R01 HL066277 (A.S. Weyrich, PI)NIH/NHLBI“Translational Events in Platelets”2003-2007AHA 034015N (A.S. Weyrich, PI)AHA/EIA“Novel Functions of p38 MAP Kinase in Platelets”2004–20141RO1 HL075507 (A.S. Weyrich, Co-Inv)NIH/NHBLI“Translational Control of Rapid Endothelial Responses”2006-2008UofU Catalyst Program (A.S. Weyrich, PI)“New Pathways to Coagulation in Thrombosis and InflammatoryDiseases”2009-20111R01HL090870 (A.S. Weyrich, PI)NIH/NHLBI“Novel Thrombotic and Inflammatory Activities of Platelets in Sepsis”2009-2011R21 HL091283 (A.S. Weyrich, PI)NIH/NHLBI“Reverse Transcriptase Activity in Megakaryocytes and Platelets”2007-2012R01 HL092746 (A.S. Weyrich, PI)NIH/NIA & NHLBI“Novel Thrombotic and Inflammatory Mechanisms of VenousThromboembolism in the Elderly”2008-2012R01 HL091754 (A.S. Weyrich, PI)NIH/NHLBI“Novel Activities of Platelets in Acute Lung Injury”2009-2012RC1 HL1000121 (A.S. Weyrich, Co-PI)“New Pathways in Thrombosis and Inflammation Mediated bySemaphorin-Plexin Signaling”2012-2018U54 HL112311-05 (A.S. Weyrich, PI)“Reprogrammed Platelets: Effectors of Thrombosis inMetabolic Syndromes”R01 AG048022 (A.S. Weyrich, Co-Inv)“Platelet Immune Responses in Aging and Influenza”2014-20192014-2019R01 HL126547 (A.S. Weyrich , Co-PI)“The Effects of ART on Platelets and HIV-Associated Thrombosis”March, 202113
Andrew S. Weyrich, PhDMentored:2000-2001American Heart Association Western Affiliate, Post-doctoral Fellowship,Mentor for Stephan Lindemann2004-2006Deutsche Forschungsgemeinschaft Award, Post-doctoral Fellowship,Mentor for Hansjorg Schwertz2006-2008American Heart Association Western Affiliate, Post-doctoral Fellowship,Mentor for Hansjorg Schwertz2007-2009National Heart, Lung, and Blood Institute (K12), Center forClinical & Translational Science,Co-mentor for Matthew Rondina2009-2010German Cardiac Society, Post-doctoral Fellowship,Mentor for Bjorn Kraemer2006-2010Flight Attendant Medical Research Fellowship,Co-mentor for Mark Martinez2006-2011National Heart, Lung, and Blood Institute (K08),Co-mentor for Christian Yost2009-2011American Heart Association Western Affiliate, BeginningGrant-in-Aid,Mentor for Hansjorg Schwertz2011-2012Primary Children’s Medical Center Foundation, EarlyCareer Development Award, Mentor for Heather Major2011-2013Deutsche Forschungsgemeinschaft Award, Post-doctoral Fellowship,Mentor for Sebastian Schubert2011-2013American Heart Association Western Affiliate, Post-doctoral Fellowship,Mentor for Robert Campbell2009-2014National Heart, Lung, and Blood Institute (K23 HL092161),Co-mentor for Matthew Rondina2012-2018National Institute of General Medical Sciences (K01),Mentor for Jesse Rowley2019-2020National Heart, Lung, and Blood Institute (SRP-2019-01)PRIDE Mentor for Donald LynchMarch, 202114
Andrew S. Weyrich, PhDX.ORIGINAL PEER-REVIEWED PUBLICATIONSManuscripts:1. Berry MJ, Robergs RA, Weyrich AS, Puntenney PJ. Ventilatory responses of trained anduntrained subjects during running and walking. Int J Sports Med 9:325-329, 1988.2. Berry MJ, Weyrich AS, Robergs RA, Krause KM, Ingalls CP. Ratings of perceivedexertion in individuals with varying fitness levels during running and walking. Eur JAppl Physiol 58:494-499, 1989.3. Weyrich AS, Messier SP, Ruhmann BS, Berry MJ. The influence of bat composition, gripfirmness and impact location on post-impact ball dynamics. Med Sci Sport Exercise21:199-205, 1989.4. Berry MJ, Puntenney PJ, Weyrich AS, Robergs RA. Stride frequency as a determinant ofthe ventilatory threshold. J Hum Movement Studies 19:129-142, 1990.5. Berry MJ, Stoneman JV, Weyrich AS, Burney B. Dissociation of the ventilatory andlactate thresholds following caffeine ingestion. Med Sci Sport and Exercise 23:463-469,1991.6. Santamore WP, Weyrich AS, Iskandrian AS. Coronary artery spasm revisited. CoronaryArtery Disease 2:259-266, 1991.7. Solis GA, Kutcher MA, Weyrich AS, Santamore WP. Albumin prevents plateletdeposition following angioplasty. J Inv Cardiol 3:265-271, 1991.8. Ma XL, Weyrich AS, Krantz S, Lefer AM. Mechanisms of the cardioprotective actions ofWEB-2170, bepafant, a platelet activating factor antagonist, in myocardial ischemia andreperfusion. J Pharmacol Exp Therap 260:1229-1236, 1992.9. Weyrich AS, Ma XL, Lefer AM. The role of L-arginine in ameliorating reperfusion injuryafter myocardial ischemia in the cat. Circulation 86:279-288, 1992.10. Weyrich AS, Rejeski WJ, Brubaker PH, Parks JS. The effects of anabolic steroids on lipidsand eicosanoids in cynomolgus monkeys. Medicine and Science in Sport and Exercise24:333-338, 1992.11. Weyrich AS, Solis GA, Li KS, Tulenko TN, Santamore WP. Platelet amplification ofvasospasm. Am J Physiol 263:H349-H358, 1992.12. Carey C, Siegfried MR, Ma XL, Weyrich AS, Lefer AM. Antishock and endothelialprotective actions of an NO donor in mesenteric ischemia and reperfusion. CirculatoryShock 38:209-216, 1992.March, 202115
Andrew S. Weyrich, PhD13. Lefer AM, Ma XL, Weyrich AS, Scalia R. Mechanisms of the cardioprotective effect oftransforming growth factor-ß1 in feline myocardial ischemia and reperfusion. Proc Nat'lAcad Sci USA 90:1018-1022, 1993. PMCID: PMC45802.14. Ma XL, Weyrich AS, Lefer DJ, Lefer AM. Diminished basal NO release after myocardialischemia and reperfusion promotes neutrophil adherence to coronary endothelium. CircRes 72:403-412, 1993.15. Weyrich AS, Ma XY, Lefer DJ, Albertine KH, Lefer AM. In vivo neutralization of Pselectin protects feline heart and endothelium in myocardial ischemia and reperfusioninjury. J Clin Invest 91:2620-2629, 1993. PMCID: PMC443326.16. Ma XL, Weyrich AS, Lefer DJ, Buerke M, Albertine KH, Kishimoto TK, Lefer AM.Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protectsischemic reperfused cat myocardium. Circulation 88:649-658, 1993.17. Buerke M, Weyrich AS, Lefer AM. Isolated cardiac myocytes are sensitized by hypoxiareoxygenation to neutrophil-released mediators. Am J Physiol 266:H128-H136, 1994.18. Lefer AM, Weyrich AS, Buerke M. Role of selectins, a new family of adhesion molecules,in ischemia-reperfusion injury. Cardiovasc Res 28:289-294, 1994.19. Buerke M, Weyrich AS, Zheng Z, Gaeta FC, Forrest MJ, Lefer AM. Sialyl Lewisxcontaining oligosaccharide attenuates myocardial reperfusion in cats. J Clin Invest93:1140-1148, 1994. PMCID: PMC294061.20. Albertine KH, Weyrich AS, Ma, XL, Lefer DJ, Becker LC, Lefer AM. Quantification ofneutrophil migration following myocardial ischemia and reperfusion in cats and dogs. JLeuk Biol 55:557-566, 1994.21. Buerke M, Weyrich AS, Murohara T, Queen C, Klingbeil CK, Co MS, Lefer AM.Humanized mAb DREG-200 directed against I-selectin protects in feline myocardialreperfusion injury. J Pharm ExpTherap 271:134-142, 1994.22. Weyrich AS, Ma XL, Buerke M, Murohara T, Armstead VE, Lefer AM, Nicolas JM,Thomas AP, Lefer DJ, Vinten-Johansen J. Physiologic concentrations of nitric oxide donot elicit an acute negative inotropic effect in unstimulated cardiac muscle. Circ Res75:692-700, 1994.23. Weyrich AS, Buerke M, Albertine KA, Lefer AM. Time course of coronary vascularendothelial adhesion molecule expression during reperfusion of ischemic felinemyocardium. Journal of Leukocyte Biology 57:45-55, 1995.March, 202116
Andrew S. Weyrich, PhD24. Weyrich AS, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. Monocytetethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosisfactor- secretion: signal integration and NF- B translocation. J Clin Invest 95:2297-2303,1995. PMCID: PMC295843.25. Weyrich AS, Elstad MR, McEver RP, McIntyre TM, Moore KL, Morrissey JH, PrescottSM, Zimmerman GA. Activated platelets signal chemokine synthesis by humanmonocytes. J Clin Invest 97:1525-1534, 1996. PMCID: PMC507213.26. Lehr HA, Weyrich AS, Saetzler RK, Jurek A, Arfors KE, Zimmerman GA, Prescott SM,McIntyre TM. Vitamin C blocks inflammatory platelet-activating factor mimetics createdby cigarette smoking. J Clin Invest 99:2358-2364, 1997. PMCID: PMC508074.27. Modur V, Feldhaus MJ, Weyrich AS, Jicha DL, Prescott SM, Zimmerman GA, McIntyreTM. Oncostatin M is a proinflammatory mediator: In vivo effects correlate withendothelial cell expression of inflammatory cytokines and adhesion molecules. J ClinInvest 100:158-168, 1997. PMCID: PMC508176.28. Hidari KI, Weyrich AS, Zimmerman GA, McEver RP. Engagement of PSGL-1 enhancestyrosine phosphorylation and activates MAP kinases in human neutrophils. J Biol Chem272:28750-28756, 1997.29. Weyrich AS, Dixon DA, Pabla R, Elstad MR, McIntyre TM, Prescott SM, ZimmermanGA. Signal-dependent translation of a regulatory protein, Bcl-3, in activated humanplatelets. PNAS 95:5556-5561, 1998. PMCID: PMC20416.30. Kessel JM, Hayflick J, Weyrich AS, Hoffman PA, Gallatin M, McIntyre TM, Prescott SM,Zimmerman GA. Coengagement of ICAM-3 and Fc receptors induces chemokinesecretion and spreading by myeloid leukocytes. J Immunol 160:5579-5587, 1998.31. Pabla R, Weyrich AS, Dixon DA, Bray PF, McIntyre TM, Prescott SM, Zimmerman GA.Integrin-dependent control of translation: Engagement of integrin IIb 3 regulatessynthesis of proteins in activated human platelets. J Cell Biol 144:175-184, 1999. PMCID:PMC2148114.32. Kraiss LW, Weyrich AS, Alto NM, Dixon DA, Ennis TM, Modur V, McIntyre TM,Prescott SM, Zimmerman GA. Fluid flow activates a regulator of translation p70/p85 S6kinase, in human endothelial cells. American Journal of Physiology 278:H1537-H1544, 2000.33. Mahoney TS, Weyrich AS, Dixon DA, McIntyre TM, Prescott SM, Zimmerman GA. Celladhesion regulates gene expression at translational checkpoints: tethering of humanmonocytes to P-selectin signals translation of urokinase plasminogen activator receptor(uPAR). PNAS 98: 10284-10289, 2001. PMCID: PMC56953.March, 202117
Andrew S. Weyrich, PhD34. Lindemann S, Tolley ND, Eyre JR, Kraiss LW, Mahoney TM, Weyrich AS. Integrinsregulate the intracellular distribution of eIF4E in platelets: a checkpoint for translationalcontrol. J Biol Chem 276:339
1985 BS, Biology Baldwin-Wallace College, Berea, OH 1987 MS, Health & Exercise Science Wake Forest University, . Molecular Medicine Program, University of Utah . Research in College of Nursing . Andrew S. Weyrich, PhD March, 2021 7
