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Thinking about becomingan egg donor?4/14/2020
Overview ofDonorOrientationWhy become an eggdonorApplication and screeningprocessEgg donation processPotential medical risksDonor recipientsPsychosocial issues
Why become an egg donor?You’ll have the satisfactionof knowing your gift madea profound difference inthe lives of peoplestruggling to becomeparents.You’ll receivecompensation for yourtime and effort.3
What to expect when donating at UCSFWe are a nationally recognized academic medical centerOur ovum donor program has helped patients becomeparents since 1991All of our providers have extensive experience with ovumdonationUCSF adheres to guidelines established by the AmericanSociety for Reproductive Medicine (ASRM)4
Application andScreening Process5
To qualify as an egg donor, you must:Be a woman between theages of 21-33Be in excellent mental andphysical healthHave a healthy familyhistoryHave a schedule flexibleenough to allow formedical appointmentsBe mature, responsible,and dependable6
What are my responsibilities if I agree tobecome a donor?Be truthful in all portions of the donor screeningFollow all medical instructionsInform us of any changes in your health, medications, orpersonal situationAgree to provide updated contact and medical informationAgree to being contacted by us in the future regarding yourdonation
Ovum Donor ApplicationSubmit initial questionnaireSubmit donor profileapplicationMedical recordsScreening consentsPhotosSchool records andconfirmation of test scores8
Orientation and application review9Presentation Title
Genetic ScreeningPersonal and familyhistory intakeThree generationpedigree generatedFamily history summaryletter written10
Psychology screening appointmentOne hour zoom meetingwith one of ourpsychologists11
Ovum Donor Screening ExamScreening toolPhotos will be taken foryour donor profileGeneral history & physicalexamBlood work: genetic testsand infectious diseasetestingMedical risk consentingFollicle count via vaginalultrasound12
Final StepsIf your application is approved,you will be notified by the eggdonor team.- If you then agree to become aUCSF donor, a profile will becreated for our database forrecipients to view.If your application is declined,you will be notified by the eggdonor team.- It’s likely you will not know specificreason for the decline.13
Matching for an upcoming cycleOnce you are selected by a recipient you will be contactedBefore agreeing to match for an upcoming cycle you shouldconsider the following issues:- Current availability and flexibility of schedule- Recent and scheduled travelIf you decide to move forward, you will complete thepreliminary paperworkDonors can donate up to 6 times in their lifetime14
Egg Donation Process15
Female reproductive cyclePituitary GlandFSHE2Fallopian TubeUterusOvaryEndometriumCervix16
The Ovaries:Natural Cycle vs. a Stimulated CycleVS.Natural Cycle17Stimulated Cycle
Will ovum donation impact my ability tohave children or deplete my eggs?There is no evidence thatthe procedure itselfimpacts your future abilityto have children.Females are born withapprox. two million eggs.Fertility medications“rescue” a portion of theseexcess eggs that the bodywould have ordinarilydiscarded.18
Monitoring appointmentsRegular monitoring appointments throughout the process- 7:30-9:30 am daily- Each visit is 15 minutes- 6 visits over 10-12 daysEgg retrieval(36hrs later)TriggerInjectionBirth ControlPills1FSH/LH Injections2345678910 11 12 13Ultrasound and Blood Monitoring19141516 17 18
Ultrasound Monitoring20
Egg Retrieval21
Fertilization: Conventional vs. ICSI22
RestrictionsandPossible Medical Risks23
What restrictions will I have during thedonation process?Once matched:- Take precautions to prevent risk of sexually transmitted infections(practice safe sex)- If you engage in sexual activity that puts you at risk forpregnancy, use condoms- From last day of oral contraceptive pills until the next period:Abstain from intercourse (one month)- From start of injections until 2 weeks after the eggretrieval: Refrain from activities that involve high impact24
MedicationsFollicle StimulationMedications- Follistim- Gonal-fMenopur- Human menopausalgonadotropin25
What are the possible medical side effectsto the medications?Allergic reactionsHot flashesHeadachesAbdominal bloating ordiscomfortNausea26
What are the possible medical risks?Ovarian hyper-stimulation syndrome (OHSS)Ovarian torsionInjury to bowel or bladderInfectionBleeding that requires surgery or transfusionOvarian cancer (no known risk)27
Insurance and Taxes28
Recipients ofEgg Donation29
Who are the recipients?Recipients are people who can’t conceive withtheir own eggs due to various factors like:-Older age (40s and early 50s)Diminished ovarian reserveCancer treatmentPoor egg qualityBorn with non-functional ovariesSame-sex male couplesSingle menOften recipients have had extensive fertilitytreatments with their own eggs without success,or they’ve experienced multiple miscarriages.While most recipients are married heterosexualcouples, your recipient may be married orsingle. They may be in a same-sex couple. Theymay need the help of a gestational carrier. Theybe of any race, religion, or ethnic background.30
What will the recipients know about me?Recipients will be able to see your profile from a secured donorwebsiteYour profile will contain:- The questionnaire you completed about yourself- Genetic and medical test results- GPA and educational standardized test results- Blood type- Height and weight- Any photographs you provide plus those taken at UCSF31
What information is kept private?Recipients will NOT receive:- Your last name, address, phone numbers, or email address toprotect your anonymitySome recipients are interested in meeting their donor- In general, no identifying information will be exchanged at themeeting32
Psychosocial ImplicationsPresentation Title33
Legal and Social ImplicationsLegally speaking, when you agree to donate your eggs,you are giving up all rights and responsibilities to theeggs, embryos, and any child born as a result of themGenetically, any offspring born as a result of your eggdonation will be half genetic siblings to your own children34
What limitations are there in termsprotecting my identity?- Photo recognition software- Donor Sibling Registry- Direct to consumer genetic testing (example: Ancestry.com)35Presentation Title
What about the future?We are committed to respecting the needs and desires ofour recipients, donors, and their respective families.You may be told the outcome of the cycle, but we can’tguarantee that information.You may be contacted in the future by us regarding yourdonation if a recipient or child requests contact. You willhave a choice about how this contact will be made.36
What else should I think about?Will I be able to manage the interruption of my daily lifeduring the cycle?How will this decision affect my current or future partner,family, and friends?How might I feel about this decision in the future?37
Thank YouBeing an ovum donor is a very generous decisionThank you for considering donating at UCSFWe welcome your questions38
Family history summary letter written. 11 Psychology screening appointment One hour zoom meeting with one of our psychologists. 12 Ovum Donor Screening Exam Screening tool Photos will be taken for your donor profile General history & physical exam Blood work: genetic tests and infectious disease
