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AP Biology Summer Assignment 2017Welcome to AP Biology! Over the summer you will be responsible for completing 4 assignments as outlined below.1.2.3.4.Writing an introductory letter to your AP Biology teacherReading The Immortal Life of Henrietta Lacks by Rebecca Skloot and answering questionsCompleting Math Problems and Graph Analysis that are relevant to AP Biology.Making a “Collection” of Biology itemsYou will be turning in various assignments at different times during the summer so make sure to read the due dates foreach assignment and get them in on time!You will be turning in all assignments in Google Classroom. Follow the instructions below to join the class and be able toaccess the assignments.1.2.3.4.5.6.Log in to your Gibbons Google accountGo to classroom.google.comClick .Enter the code: f17r0z in the box and click Join.You now have access to the assignments.Make sure you hit the “Turn in” button to submit your work!If you need help with Google Classroom visit this opic 6020277If you have any questions over the summer, please contact Ms. Kuszaj via e-mail at skuszaj@cghsnc.orgWe look forward to seeing you in class in August!

Assignment Part 1LETTER OF INTRODUCTIONWelcome to AP Biology!We will spend a lot of time together next year, so it’s best if I get a head start on learning a bit about you. Also we will usethe Internet and the Web a lot next year for this course, so let’s get you used to communicating via Google Classroom.Your first digital assignment is to successfully attach a document to an assignment in Google Classroom.Due date: Friday June 16, 2017Draft a letter to me following these rules:a. Use clearly written, full sentences. Do not abbreviate words like you are texting with a friend. Use spell check! This isa professional communication like you would have with a college professor, so let’s practice for your rapidly nearingfuture!b. Make the Title: “AP Bio: Introduction to Insert Your Name Here ”c. Begin the letter with a formal salutation, like “Dear AP Bio Teacher”d. Now introduce yourself (your name) and tell a little bit about yourself, like: What do you like to do (hobbies, sports, music, interests, etc.)? Do you have a job? Tell me a little bit about your family (Mom? Dad? Guardian? Siblings? Pets?) What do your parents do for a living? What do you want to do after high school? Was there anything that you liked about your earlier biology class? What was the last book you read for fun? What are you looking forward to the most in AP Biology? What are you most anxious about in AP Biology?Assignment Part 2The Immortal Life of Henrietta LacksDIRECTIONS1. Read The Immortal Life of Henrietta Lacks By Rebecca Skloot and then answer the discussion questions from theRandom House Reading Guide listed below.2. Assignment is split between: Prologue, Chapters 1-11 and #s1-8 of Chapters 12-20 due by Friday June 30th via Google Classroom.Make sure you hit the “Turn in” button to submit your work! #s 9-18 from Chapters 12-20, Chapters 21-36 and Overall Questions due by Sunday July 30th via GoogleClassroom. Make sure you hit the “Turn in” button to submit your work!3. Assignment must be typed directly into the document (12 pt font) and answers should be clearly labeled & numberedfor each chapter. Feel free to use a different color font to differentiate your answers from the questions. Answercompletely and in full sentences. Use good grammar and spelling (AP style) but be clear and concise; discussion shouldbe in your own words even if page numbers are referenced.Prologue: The Woman in the Photograph1. What happens when there is a mistake during the process of mitosis?2. According to Defler, how important was the discovery of HeLa cells?

Chapters 1-111. What did Howard Jones find “interesting” about Henrietta’s medical history? What does this finding suggestabout Henrietta’s cancer?2. How are different types of cancer categorized?3. Summarize Dr. TeLinde’s position in the debate over the treatment of cervical cancer.4. Explain how the development of the Pap smear improved the survival rate of women diagnosed with cervicalcancer.5. How did TeLinde hope to prove that his hypothesis about cervical cancer was correct?6. Explain what an immortal cell line is.7. Summarize the main obstacles Gey and his assistants faced in their effort to grow cells.8. Where did the name “HeLa” come from?9. What happened to the HeLa cells that Mary cultured?10. What did Gey hope to accomplish with HeLa cells?11. What did HeLa allow scientists to do for the first time?12. How did the media react to Carrel’s announcement that he had grown immortal chicken heart cells?13. What details suggest that Carrel’s claims about the immortal cell line were not scientifically sound?14. After her initial round of treatment, what did Henrietta’s doctors assume about the effectiveness of the radiumtherapy?15. Describe the progression of Henrietta’s cancer in the eight months between her diagnosis and her death.Chapters 12-20:1. Explain how a neutralization test is used to determine a vaccine’s efficacy.2. What unusual characteristics of HeLa cells made them ideal for use in the polio vaccine trials?3. Paraphrase the explanation of how a virus reproduces found on page 97. Why did the fact that HeLa cells aremalignant make them particularly useful in the study of viruses?4. Why was the development of methods of freezing cells an important scientific breakthrough?5. Why did scientists want to be able to clone cells for research?6. Explain the contribution that HeLa made to the emerging field of genetics.7. Describe the experiment that Southam developed to test his hypothesis about HeLa.8. What was the result of Southam’s first research study? Based on these results, did his hypothesis appear to becorrect?9. Based on the results of the second study, what two things did Southam believe that injections of HeLa cells mightbe able to do?10. How did Southam justify his decision to inject HeLa cells into patients without their knowledge or consent?11. Summarize the various ways that HeLa was used in the space program.12. What disturbing discovery did scientists make about the way HeLa responded in orbit?13. Explain what happens during somatic cell fusion.14. What scientific discoveries were made possible as a result of fused hybrid cells?15. How was Gartler able to link the contamination problem to HeLa?16. What unique abilities did HeLa have that allowed it to contaminate cultures without researchers being aware thatcontamination had occurred?17. Why would HeLa contamination be a problem for researchers?18. What is “spontaneous transformation”? What did Gartler suggest about spontaneous transformation?Chapters 21-361. What was the purpose of President Nixon’s National Cancer Act?2. Why did advances in genetic research necessitate establishing the legal requirement that doctors or researchersobtain informed consent documentation prior to taking DNA samples from patients for research?3. Describe the lawsuit that set a legal precedent for patenting biological “products” such as cell lines.4. Summarize the pros and cons of giving patients legal ownership of their cells.5. What was the Supreme Court of California’s decision regarding the Moore lawsuit? Summarize the reasoningbehind the decision.6. Explain how the human papillomavirus (HPV) causes cervical cancer.7. Are scientists able to definitively explain why HeLa grew so powerfully?8. Describe the contribution that HeLa has made to research on the HIV virus and the AIDS epidemic.

9. Explain Van Valen’s theory that HeLa cells are “no longer human.” Was his theory accepted by the scientificcommunity?10. Explain the Hayflick limit.11. Why are HeLa cells able to live beyond the Hayflick limit?12. Summarize Gary’s spiritual explanation for why Henrietta’s cells lived on after her death.Overall Questions:1. There is often a tension between religious faith and science. Explore the importance of both religious faith andscientific understanding in the lives of the Lacks family. How does religious faith help frame the Lackses’response to, and interpretation of, the scientific information they receive about HeLa? How does Skloot’s attitudetoward the relationship between religious faith and science evolve as a result of her relationship with the Lacksfamily?2. Using the book as a guide, describe the process of scientific inquiry. Examine the often contradictory forces ofaltruism and profit as they influenced research related to HeLa. What are the risks and benefits of allowing profitto guide research? What are the obstacles involved with conducting research purely for altruistic reasons?3. Create a time line that begins with the removal of Henrietta’s tissue sample and traces the scientific and medicalbreakthroughs that have been made possible as a result of HeLa cells. Explain how HeLa cells were used in eachsituation.Assignment Part 3Math Practice1. Read the information about interpreting graphs on Google Classroom2. Complete the Graphing Practice Packet and submit via Classroom by Sunday July 30th3. Complete the Math Problems Summer Packet on Classroom to the best of your ability, use the formula sheet onClassroom to help you and submit via Classroom by Friday August 18thAP Biology Graphing Summer PacketInterpreting GraphsThe graph to the below represents the typical day of a teenager. Answer these questions in complete sentences.4. What percent of the day is spent watching TV?5. How many hours are spent sleeping?6. What activity takes up the least amount of time?

7. What activity takes up a quarter of the day?8. What two activities take up 50% of the day?9. What two activities take up 25% of the day?Answer these questions about the graph below in complete sentences.10. How many total miles did the car travel?11. Describe the motion of the car between hours 5 and 12?12. What direction is represented by line CD?13. How many miles were traveled in the first two hours of the trip?The bar graph below represents the declared majors of freshman enrolling at a university. Answer the following questionsin complete sentences.

14. What is the total freshman enrollment of the college?15. What percent of the students are majoring in physics?16. How many students are majoring in economics?17. How many more students major in poly sci than in psych?Answer these questions about the graph below in complete sentences.18. How much rain fell in Mar of 1989?

19. How much more rain fell in Feb of 1990 than in Feb of 1989?20. Which year had the most rainfall?21. What is the wettest month on the graph?AP Biology Math Problems Summer PacketInstructions: Show all work to get full credit. Step by step. See Equation SheetRounding Places: ReviewExample: .123The 1 is in the tenths place The 2 is in the hundreds place The 3 is in the thousandths placeWater PotentialY Ys YpYs -iCRT i The number of particles the molecule will make in water; for NaCl this would be 2; for sucrose or glucose, thisnumber is 1 C Molar concentration (from your experimental data; where the line of best fit crosses the x-axis) R Pressure constant 0.0831 liter bar/mole K T Temperature in degrees Kelvin 273 C of solutionSample Problem: TRY Your Best1. The molar concentration of a sugar solution in an open beaker has been determined to be 0.3M. Calculate the solutepotential at 27 oC. Round your answer to the nearest tenths.2. If a baby carrot with a water potential of 5.2 bars is put into this solution, what will happen? Why?Laws of Probability3. Calculate the probability of tossing three coins simultaneously and obtaining three heads. Express in fraction form.Surface Area and Volume4. What is the surface area to volume ratio for this cell? Round your answer to the nearest hundredths