Evidence Brief: Transcranial Magnetic Stimulation (TMS .

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Evidence Synthesis ProgramEvidence Brief: TranscranialMagnetic Stimulation (TMS) forChronic Pain, PTSD, TBI, OpioidAddiction, and Sexual TraumaSupplementary MaterialsDecember 2020Prepared for:Department of Veterans AffairsVeterans Health AdministrationHealth Services Research & DevelopmentServiceWashington, DC 20420Authors:Johanna Anderson, MPHNicholas J. Parr, PhD, MPHKathryn Vela, MLISPrepared by:Evidence Synthesis Program (ESP)Coordinating CenterPortland VA Medical CenterPortland, ORMark Helfand, MD, MPH, MS, Director

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis ProgramTABLE OF CONTENTSAppendix A: VA/DoD Guidelines . 1Appendix B: Searches . 2Appendix C: Excluded Studies . 12Appendix D: Studies Included in Existing Systematic Review (O’Connell 2018) . 18Appendix E: Ongoing Studies . 34Opioid Use Disorder . 34PTSD . 35Traumatic Brain Injury (TBI) . 36Pain . 36Alcohol Use Disorder . 37Appendix F: Data Abstraction. 38Controlled Studies . 38Pain . 38PTSD . 44TBI . 48Opiate Addiction. 51Case Series . 52Appendix G: Quality Assessment Tables. 55Quality Assessment of RCTs . 55Quality Assessment of Cohort Studies . 67Appendix H: Strength of Evidence. 69Peer Review Comments Table . 74References . 77i

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis ProgramAPPENDIX A: VA/DOD GUIDELINESYearTitleConditionTMS-related guidance2017Management ofPosttraumatic StressDisorder and Acute StressReaction 2017PTSD/AcuteThere is insufficient evidence to recommendStress Reaction for or against the following somatic therapies:repetitive transcranial magnetic stimulation(rTMS), electroconvulsive therapy (ECT),hyperbaric oxygen therapy (HBOT), stellateganglion block (SGB), or vagal nervestimulation (VNS).2020The Primary CareManagement of HeadacheHeadache2016Management of Concussion- Concussion/mild There is no evidence to suggest for or againstmild Traumatic Brain InjuryTraumatic Brain the use of any particular modality for the(mTBI)Injury (mTBI)treatment (including rTMS) of tinnitus aftermTBI.There is insufficient evidence to recommendfor or against the following for headache: Transcranial magnetic stimulation Transcranial direct current stimulation External trigeminal nerve stimulation Supraorbital electrical stimulation1

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis ProgramAPPENDIX B: SEARCHES1. Search for current systematic reviews (limited to last 7 years)Date Searched: 08-06-2020A. Bibliographic #Search StatementDatabases:MEDLINE:1Transcranial Magnetic Stimulation/Systematic2(transcranial magnetic stimulation 1 or rTMS or TMS).mp.Reviews31 or 2(systematic review.ti. or meta-analysis.pt. or meta-analysis.ti. orOvidsystematic literature review.ti. or this systematic review.tw. orMEDLINE(R)pooling project.tw. or (systematic review.ti,ab. and review.pt.) orand Epubmeta synthesis.ti. or meta-analy*.ti. or integrative review.tw. orAhead of Print,integrative research review.tw. or rapid review.tw. or umbrellaIn-Process &review.tw. or consensus development conference.pt. or practiceOther Nonguideline.pt. or drug class reviews.ti. or cochrane database systIndexedrev.jn. or acp journal club.jn. or health technol assess.jn. or evidCitations, Dailyrep technol assess summ.jn. or jbi database system revand Versions(R)implement rep.jn. or (clinical guideline and management).tw. or1946 to February((evidence based.ti. or evidence-based medicine/ or best05, 2020practice*.ti. or evidence synthesis.ti,ab.) and (((review.pt. ordiseases category/ or behavior.mp.) and behavior mechanisms/)or therapeutics/ or evaluation studies.pt. or validation studies.pt.or guideline.pt. or pmcbook.mp.)) or (((systematic or4systematically).tw. or critical.ti,ab. or study selection.tw. or((predetermined or inclusion) and criteri*).tw. or exclusioncriteri*.tw. or main outcome measures.tw. or standard of care.tw.or standards of care.tw.) and ((survey or surveys).ti,ab. oroverview*.tw. or review.ti,ab. or reviews.ti,ab. or search*.tw. orhandsearch.tw. or analysis.ti. or critique.ti,ab. or appraisal.tw. or(reduction.tw. and (risk/ or risk.tw.) and (death orrecurrence).mp.)) and ((literature or articles or publications orpublication or bibliography or bibliographies or published).ti,ab. orpooled data.tw. or unpublished.tw. or citation.tw. or citations.tw. ordatabase.ti,ab. or internet.ti,ab. or textbooks.ti,ab. orreferences.tw. or scales.tw. or papers.tw. or datasets.tw. ortrials.ti,ab. or meta-analy*.tw. or (clinical and studies).ti,ab. ortreatment outcome/ or treatment outcome.tw. or pmcbook.mp.)))not (letter or newspaper article).pt.53 and 46limit 5 to english language7Results:110132120121201382964717686limit 6 to last 7 years545CDSR: Protocolsand Reviews1Transcranial Magnetic Stimulation/02(transcranial magnetic stimulation 1 or rTMS or TMS).mp.68EBM Reviews CochraneDatabase ofSystematicReviews 2005 toFebruary 4, 202031 or 268474limit 3 to last 7 years2

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis Program2. Search for systematic reviews currently under development (includes forthcoming reviews &protocols)Date Searched: 08-06-20D. ww.crd.york.ac.uk/PROSPERO/0(SR registry)Search: TMS; transcranial magnetic stimulationDoPHER ntro.aspx?ID 9CochraneDatabase d/education/library/0Search: TMS; transcranial magnetic stimulation0See Cochrane search above3. Search for primary literatureDate searched: 08-15-20MEDLINE [Ovid MEDLINE(R) ALL 1946 to July 14, 2020]#Search Statement1Transcranial Magnetic Stimulation/(transcranial magnetic stimulation 1 or rTMS or TMS or (repetitive adj transcranial2magnetic stimulation 1) or (single-pulse adj transcranial magnetic stimulation 1) or(paired?pulse adj transcranial magnetic stimulation 1)).ti,ab,kw.31 or 24Chronic Pain/5(chronic adj1 pain).ti,ab,kw.64 or 573 and 68limit 7 to english language9limit 8 to yr ”2017-Current”CINAHL [EBSCO]#Search Statement1(MH "Transcranial Magnetic Stimulation")TI ( (transcranial magnetic stimulation# or rTMS or TMS or (repetitive N1 transcranialmagnetic stimulation#) or (single-pulse N1 transcranial magnetic stimulation#) or (pairedpulse N1 transcranial magnetic stimulation#)) ) OR AB ( (transcranial magnetic2stimulation# or rTMS or TMS or (repetitive N1 transcranial magnetic stimulation#) or(single-pulse N1 transcranial magnetic stimulation#) or (paired?pulse N1 transcranialmagnetic stimulation#)) )31 or 24(MH "Chronic Pain")5TI (chronic N1 pain) OR AB (chronic N1 pain)64 or 573 and ults123436373896235752746638370118

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis Program8limit 7 to english language9limit 8 to 2017-CurrentCCRCT [EBM Reviews - Cochrane Central Register of Controlled Trials June 2020]#Search Statement1Transcranial Magnetic Stimulation/(transcranial magnetic stimulation 1 or rTMS or TMS or (repetitive adj transcranial2magnetic stimulation 1) or (single-pulse adj transcranial magnetic stimulation 1) or(paired?pulse adj transcranial magnetic stimulation 1)).ti,ab,kw.31 or 24Chronic Pain/5(chronic adj1 pain).ti,ab,kw.64 or 573 and 68limit 7 to english language9limit 8 to yr ”2017-Current”4. Search for primary literature - TMS-all PTSD/TBI/Opioid addiction/MSTDate searched: 08-10-20MEDLINE [Ovid MEDLINE(R) ALL 1946 to August 07, 2020]#Search Statement1exp Transcranial Magnetic Stimulation/ or Magnetic Stimulation Therapy/(TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or2((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*) or(transcranial magnetic stimulation or rTMS or cranial electrostimulation or cranialelectrotherapy)).ti,ab,kw.(MeRT or magnetic eResonance therapy or magnetic e-Resonance3therapy).ti,ab,kw.(magnetic EEG?EKG guidance resonance therapy or magnetic EEG guided4resonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy).ti,ab,kw.(EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKG guidedTMS or EKG-guided TMS or EEG guided transcranial magnetic stimulation or EEG5guided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or EKG guided transcranial magnetic stimulation or q-EEG or quantitativeEEG).ti,ab,kw.6or/1-5Stress Disorders, Post-Traumatic/ or exp Brain Injuries, Traumatic/ or exp Opioid7Related Disorders/ or Sexual Harassment/ or exp Sex Offenses/8(PTSD or post-traumatic stress disorder or posttraumatic stress disorder or posttraumatic stress disorders or posttraumatic stress disorders or post-traumaticneuroses or posttraumatic neuroses or moral injury or moral injuries).ti,ab,kw.9(TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma orbrain traumas or traumatic encephalopathy or traumatic encephalopathies).ti,ab,kw.10(opioid related disorders or opioid-related disorders or opioid addiction or opioidaddictions or opioid dependence or opioid dependences or opiate abuse or opiateabuses or opiate dependence or opiate addiction or opioid abuse or 3034503440657202

Evidence Brief: TMS for Conditions Other than Depression11Evidence Synthesis Program((sexual* adj1 (trauma or abuse or violence or harassment or assault or assults orassulted) or (sex* adj1 offense or offenses) or rape or raped)).ti,ab,kw.12or/7-11136 and 1214limit 13 to english language15limit 14 to yr ”2012-Current”CINAHL [EBSCO]#Search Statement1(MH "Transcranial Magnetic Stimulation")TI ( (TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*) or(transcranial magnetic stimulation or rTMS or cranial electrostimulation or cranialelectrotherapy)) ) OR AB ((TMS or ((transcrani* or crani* or brain*) adj4 (electrostim*or electro-stim* or electrotherap* or electro-therap*)) or electrical stimulation or2electrical treatment or ((brain* or cortex or cortical or transcranial* or cranial ormagneti*) adj4 stimulat*) or (transcranial magnetic stimulation or rTMS or cranialelectrostimulation or cranial electrotherapy)) ) OR SU ((TMS or ((transcrani* or crani*or brain*) adj4 (electrostim* or electro-stim* or electrotherap* or electro-therap*)) orelectrical stimulation or electrical treatment or ((brain* or cortex or cortical ortranscranial* or cranial or magneti*) adj4 stimulat*) or (transcranial magneticstimulation or rTMS or cranial electrostimulation or cranial electrotherapy)) )TI ( (MeRT or magnetic eResonance therapy or magnetic e-Resonance therapy) )OR AB ( (MeRT or magnetic eResonance therapy or magnetic e-Resonance3therapy) ) OR SU ( (MeRT or magnetic eResonance therapy or magnetic eResonance therapy) )TI ( (magnetic EEG?EKG guidance resonance therapy or magnetic EEG guidedresonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) ) OR AB ((magnetic EEG?EKG guidance resonance therapy or magnetic EEG guided4resonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) ) OR SU ((magnetic EEG?EKG guidance resonance therapy or magnetic EEG guidedresonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) )TI ( (EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKGguided TMS or EKG-guided TMS or EEG guided transcranial magnetic stimulation orEEG-guided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or EKG guided transcranial magnetic stimulation or q-EEG or quantitativeEEG) ) OR AB ( (EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMSor EKG guided TMS or EKG-guided TMS or EEG guided transcranial magnetic5stimulation or EEG-guided transcranial magnetic stimulation or EKG guidedtranscranial magnetic stimulation or EKG guided transcranial magnetic stimulation orq-EEG or quantitative EEG) ) OR SU ( (EEG?EKG guided TMS or EEG guided TMSor EEG-guided TMS or EKG guided TMS or EKG-guided TMS or EEG guidedtranscranial magnetic stimulation or EEG-guided transcranial magnetic stimulation orEKG guided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or q-EEG or quantitative EEG) )6S1 OR S2 OR S3 OR S4 OR S5(MH "Stress Disorders, Post-Traumatic ") OR (MH "Brain Injuries ") OR (MH7"Sexual Harassment") OR (MH "Substance Use Disorders ")TI ( (PTSD or post-traumatic stress disorder or posttraumatic stress disorder or post8traumatic stress disorders or posttraumatic stress disorders or 94002261062221468016203

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis Programneuroses or posttraumatic neuroses or moral injury or moral injuries) ) OR AB ((PTSD or post-traumatic stress disorder or posttraumatic stress disorder or posttraumatic stress disorders or posttraumatic stress disorders or post-traumaticneuroses or posttraumatic neuroses or moral injury or moral injuries) ) OR SU ((PTSD or post-traumatic stress disorder or posttraumatic stress disorder or posttraumatic stress disorders or posttraumatic stress disorders or post-traumaticneuroses or posttraumatic neuroses or moral injury or moral injuries) )TI ( (TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma orbrain traumas or traumatic encephalopathy or traumatic encephalopathies) ) OR AB ((TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma or9brain traumas or traumatic encephalopathy or traumatic encephalopathies) ) OR SU( (TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma orbrain traumas or traumatic encephalopathy or traumatic encephalopathies) )TI ( (opioid related disorders or opioid-related disorders or opioid addiction or opioidaddictions or opioid dependence or opioid dependences or opiate abuse or opiateabuses or opiate dependence or opiate addiction or opioid abuse or opioid abuses) )OR AB ( (opioid related disorders or opioid-related disorders or opioid addiction oropioid addictions or opioid dependence or opioid dependences or opiate abuse or10opiate abuses or opiate dependence or opiate addiction or opioid abuse or opioidabuses) ) OR SU ( (opioid related disorders or opioid-related disorders or opioidaddiction or opioid addictions or opioid dependence or opioid dependences or opiateabuse or opiate abuses or opiate dependence or opiate addiction or opioid abuse oropioid abuses) )TI ( ((sexual* adj1 (trauma or abuse or violence or harassment or assault or assultsor assulted) or (sex* adj1 offense or offenses) or rape or raped)) ) OR AB ( ((sexual*adj1 (trauma or abuse or violence or harassment or assault or assults or assulted) or11(sex* adj1 offense or offenses) or rape or raped)) ) OR SU ( ((sexual* adj1 (trauma orabuse or violence or harassment or assault or assults or assulted) or (sex* adj1offense or offenses) or rape or raped)) )12S7 or S8 or S9 or S10 or S1113S6 and S1214limit 13 to english language15limit 14 to yr ”2012-Current”CCRCT [EBM Reviews - Cochrane Central Register of Controlled Trials July 2020]#Search Statement1exp Transcranial Magnetic Stimulation/ or Magnetic Stimulation Therapy/(TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or2((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*) or(transcranial magnetic stimulation or rTMS or cranial electrostimulation or cranialelectrotherapy)).ti,ab,kw.(MeRT or magnetic eResonance therapy or magnetic e-Resonance3therapy).ti,ab,kw.(magnetic EEG?EKG guidance resonance therapy or magnetic EEG guided4resonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy).ti,ab,kw.(EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKG guidedTMS or EKG-guided TMS or EEG guided transcranial magnetic stimulation or EEG5guided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or EKG guided transcranial magnetic stimulation or q-EEG or 968283282191Results1537171328030917606

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis ProgramStress Disorders, Post-Traumatic/ or exp Brain Injuries, Traumatic/ or exp OpioidRelated Disorders/ or Sexual Harassment/ or exp Sex Offenses/8(PTSD or post-traumatic stress disorder or posttraumatic stress disorder or posttraumatic stress disorders or posttraumatic stress disorders or post-traumaticneuroses or posttraumatic neuroses or moral injury or moral injuries).ti,ab,kw.9(TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma orbrain traumas or traumatic encephalopathy or traumatic encephalopathies).ti,ab,kw.10(opioid related disorders or opioid-related disorders or opioid addiction or opioidaddictions or opioid dependence or opioid dependences or opiate abuse or opiateabuses or opiate dependence or opiate addiction or opioid abuse or opioidabuses).ti,ab,kw.11(sexual* trauma or sexual* abuse or sexual* violence or sex* offense or sex*offenses or sexual* harassment or sexual* assault or sexual* assaults or sexual*assaulted or rape or raped).ti,ab,kw.12or/7-11136 and 1214limit 13 to english language15limit 14 to yr ”2012-Current”PsycINFO [Ovid, APA PsycInfo 1806 to August Wk 1 2020]#Search Statement1exp Transcranial Magnetic Stimulation/(TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or2((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*) or(transcranial magnetic stimulation or rTMS or cranial electrostimulation or cranialelectrotherapy)).ti,ab,id.3(MeRT or magnetic eResonance therapy or magnetic e-Resonance therapy).ti,ab,id.(magnetic EEG?EKG guidance resonance therapy or magnetic EEG guided4resonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy).ti,ab,id.(EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKG guidedTMS or EKG-guided TMS or EEG guided transcranial magnetic stimulation or EEG5guided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or EKG guided transcranial magnetic stimulation or q-EEG or quantitativeEEG).ti,ab,id.6or/1-5exp Posttraumatic Stress Disorder/ or exp Traumatic Brain Injury/ or exp “Opioid Use7Disorder”/ or exp Sexual Harassment/ or exp Sex Offenses/8(PTSD or post-traumatic stress disorder or posttraumatic stress disorder or posttraumatic stress disorders or posttraumatic stress disorders or post-traumaticneuroses or posttraumatic neuroses or moral injury or moral injuries).ti,ab,id.9(TBI or TBIs or traumatic brain injury or traumatic brain injuries or brain trauma orbrain traumas or traumatic encephalopathy or traumatic encephalopathies).ti,ab,id.10(opioid related disorders or opioid-related disorders or opioid addiction or opioidaddictions or opioid dependence or opioid dependences or opiate abuse or opiateabuses or opiate dependence or opiate addiction or opioid abuse or opioidabuses).ti,ab,id.11(sexual* trauma or sexual* abuse or sexual* violence or sex* offense or sex*offenses or sexual* harassment or sexual* assault or sexual* assaults or sexual*assaulted or rape or 909435842333122224

Evidence Brief: TMS for Conditions Other than Depression131415Evidence Synthesis Program6 and 12limit 13 to english languagelimit 14 to yr ”2012-Current”4884683145. Search for primary literature - TMS-all Chronic pain-post2017Date searched: 08-10-20MEDLINE [Ovid MEDLINE(R) ALL 1946 to August 06, 2020]#Search Statement1exp Transcranial Magnetic Stimulation/ or Magnetic Stimulation Therapy/(TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*)2or (transcranial magnetic stimulation or rTMS or cranial electrostimulation orcranialelectrotherapy)).ti,ab,kw.(MeRT or magnetic eResonance therapy or magnetic e-Resonance3therapy).ti,ab,kw.(magnetic EEG?EKG guidance resonance therapy or magnetic EEG guided4resonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy).ti,ab,kw.(EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKG guidedTMS or EKG-guided TMS or EEG guided transcranial magnetic stimulation or5EEG-guided transcranial magnetic stimulation or EKG guided transcranialmagnetic stimulation or EKG guided transcranial magnetic stimulation or q-EEG orquantitative EEG).ti,ab,kw.6or/1-57Chronic Pain/8((chronic* or back or musculoskel* or intractabl* or neuropath* or phantom limb orfantom limb or neck or myofasc* or "temporomandib* joint*" or "temperomandib*joint*" or "tempromandib* joint*" or central or post*stroke or complex or regional orspinal cord) adj4 pain*) or (sciatica or back-ache or back*ache or lumbago orfibromyalg* or (trigemin* adj2 neuralg*) or (herp* adj2 neuralg*) or (diabet* adj2neuropath*) or (reflex adj4 dystroph*) or (sudeck* adj2 atroph*) or causalg* orwhip-lash or whip*lash or polymyalg* or (failed back adj4 surg*) or (failed backadj4 syndrome*)).ti,ab,kw.97 or 8106 and 911limit 10 to english language12limit 11 to yr ”2017-current”CINAHL [EBSCO]#Search Statement1(MH "Transcranial Magnetic Stimulation")TI ( (TMS or ((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* orelectrotherap* or electro-therap*)) or electrical stimulation or electrical treatment or((brain* or cortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*)or (transcranial magnetic stimulation or rTMS or cranial electrostimulation or2cranialelectrotherapy)) ) OR AB ((TMS or ((transcrani* or crani* or brain*) adj4(electrostim* or electro-stim* or electrotherap* or electro-therap*)) or electricalstimulation or electrical treatment or ((brain* or cortex or cortical or transcranial* orcranial or magneti*) adj4 stimulat*) or (transcranial magnetic stimulation or 0628872719674Results121510359

Evidence Brief: TMS for Conditions Other than Depression345678Evidence Synthesis Programor cranial electrostimulation or cranial electrotherapy)) ) OR SU ((TMS or((transcrani* or crani* or brain*) adj4 (electrostim* or electro-stim* or electrotherap*or electro-therap*)) or electrical stimulation or electrical treatment or ((brain* orcortex or cortical or transcranial* or cranial or magneti*) adj4 stimulat*) or(transcranial magnetic stimulation or rTMS or cranial electrostimulation or cranialelectrotherapy)) )TI ( (MeRT or magnetic eResonance therapy or magnetic e-Resonance therapy) )OR AB ( (MeRT or magnetic eResonance therapy or magnetic e-Resonancetherapy) ) OR SU ( (MeRT or magnetic eResonance therapy or magnetic eResonance therapy) )TI ( (magnetic EEG?EKG guidance resonance therapy or magnetic EEG guidedresonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) ) OR AB ((magnetic EEG?EKG guidance resonance therapy or magnetic EEG guidedresonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) ) OR SU ((magnetic EEG?EKG guidance resonance therapy or magnetic EEG guidedresonance therapy or magnetic EEG-guided resonance therapy or magnetic EKGguided resonance therapy or magnetic EKG-guided resonance therapy) )TI ( (EEG?EKG guided TMS or EEG guided TMS or EEG-guided TMS or EKGguided TMS or EKG-guided TMS or EEG guided transcranial magnetic stimulationor EEG-guided transcranial magnetic stimulation or EKG guided transcranialmagnetic stimulation or EKG guided transcranial magnetic stimulation or q-EEG orquantitative EEG) ) OR AB ( (EEG?EKG guided TMS or EEG guided TMS or EEGguided TMS or EKG guided TMS or EKG-guided TMS or EEG guided transcranialmagnetic stimulation or EEG-guided transcranial magnetic stimulation or EKGguided transcranial magnetic stimulation or EKG guided transcranial magneticstimulation or q-EEG or quantitative EEG) ) OR SU ( (EEG?EKG guided TMS orEEG guided TMS or EEG-guided TMS or EKG guided TMS or EKG-guided TMSor EEG guided transcranial magnetic stimulation or EEG-guided transcranialmagnetic stimulation or EKG guided transcranial magnetic stimulation or EKGguided transcranial magnetic stimulation or q-EEG or quantitative EEG) )S1 OR S2 OR S3 OR S4 OR S5(MH "Chronic Pain")TI ( ((chronic* or back or musculoskel* or intractabl* or neuropath* or phantomlimb or fantom limb or neck or myofasc* or "temporomandib* joint*" or"temperomandib* joint*" or "tempromandib* joint*" or central or post*stroke orcomplex or regional or spinal cord) adj4 pain*) or (sciatica or back-ache orback*ache or lumbago or fibromyalg* or (trigemin* adj2 neuralg*) or (herp* adj2neuralg*) or (diabet* adj2 neuropath*) or (reflex adj4 dystroph*) or (sudeck* adj2atroph*) or causalg* or whip-lash or whip*lash or polymyalg* or (failed back adj4surg*) or (failed back adj4 syndrome*)) ) OR AB ( ((chronic* or back ormusculoskel* or intractabl* or neuropath* or phantom limb or fantom limb or neckor myofasc* or "temporomandib* joint*" or "temperomandib* joint*" or"tempromandib* joint*" or central or post*stroke or complex or regional or spinalcord) adj4 pain*) or (sciatica or back-ache or back*ache or lumbago or fibromyalg*or (trigemin* adj2 neuralg*) or (herp* adj2 neuralg*) or (diabet* adj2 neuropath*) or(reflex adj4 dystroph*) or (sudeck* adj2 atroph*) or causalg* or whip-lash orwhip*lash or polymyalg* or (failed back adj4 surg*) or (failed back adj4syndrome*)) ) OR SU ( ((chronic* or back or musculoskel* or intractabl* orneuropath* or phantom limb or fantom limb or neck or myofasc* or"temporomandib* joint*" or "temperomandib* joint*" or "tempromandib* joint*" orcentral or post*stroke or complex or regional or spinal cord) adj4 pain*) or (sciaticaor back-ache or back*ache or lumbago or fibromyalg* or (trigemin* adj2 neuralg*)or (herp* adj2 neuralg*) or (diabet* adj2 neuropath*) or (reflex adj4 dystroph*) or940022610622129585599

Evidence Brief: TMS for Conditions Other than DepressionEvidence Synthesis Program(sudeck* adj2 atroph*) or causalg* or whip-lash or whip*lash or polymyalg* or(failed back adj4 surg*) or (failed back adj4 syndrome*)) )9S7 or S810S6 and S911limit 10 to english language12limit 11 to yr ”2017-current”CCRCT [EBM Reviews - Cochrane

Aug 06, 2020 · 2016 Management of Concussion-mild Traumatic Brain Injury (mTBI) Concussion/mild Traumatic Brain Injury (mTBI) There is no evidence to suggest for or against . (transcranial magnetic stimulation or rTMS or cranial electro