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AHInter ybridaMee ctiveting2022 Neurology Update –A Comprehensive Reviewfor the ClinicianFeaturing up to 17 CME creditsABPN-Approved for Self-Assessment CreditsAugust 5-7, 2022The Ritz-Carlton, Washington DCFeatured TopicsCNS InfectionsDementiaEpilepsyHeadacheHiFu in TremorHydrocephalusMovement DisordersMultiple SclerosisNeurology ConsultNeuromuscular EMGNeuroradiologySleep DisordersStrokeSyncopewww.ccfcme.org/NeuroUpdate

WelcomeAbout the CourseWelcome to the 13th Annual Cleveland Clinic Neurology Update. On behalf of the NeurologicalInstitute at the Cleveland Clinic we would like to welcome you to our annual course and hopeyou find it valuable in your continuing care of patients with neurological disease. We are excitedto bring you our first hybrid meeting that is a clinically focused review course with updatedinformation on a broad range of neurological conditions. We have incorporated smaller groupbreakout sessions for a more connected interaction and experience. The three breakouts willfocus on neuromuscular EMG cases, headache management and movement disorders. Allcourse participants will have a chance to attend each session.This year we will discuss neurological approaches to syncope, neuroradiology (brain andspine) and neurology consult cases. We will continue to include presentations on stroke (acuteupdates), epilepsy (ASMs), multiple sclerosis, and dementia. The course will also address sleepdisorders, CNS infections, hydrocephalus and HiFu for tremor. Our interactive course will allowtime for Q&A after each lecture and we will encourage active participation using the audienceresponse/polling system to incorporate a self-assessment where you will see how your answerchoices compare to your peers.The course will also continue to offer CME Self-Assessment credits approved by the AmericanBoard of Psychiatry and Neurology for Maintenance of Certification mandated by ABMS.We hope this course adds to your knowledge base and enhances patient care.We look forward to learning with you during this course!Glen Stevens, DO, PhD, FAANCourse Co-DirectorRobert Marquardt, DOCourse Co-DirectorTarget AudienceThis course is directed towards neurologists, internists and family practice physicians,advanced practice providers including PAs and NPs, nurses and others involved in thediagnosis and treatment of neurological disorders.ObjectivesUpon completion of this activity, the participant will be able to: Provide an update of advances in acute stroke care including prevention, treatment, andrehabilitation. Describe recent technologic innovations in radiologic imaging and their impact onneuroradiologic clinical practice. Summarize advances in epilepsy treatments and describe their best use in clinicalpractice. Apply current headache management strategies to individual cases. Review the recent research on multiple sclerosis and its impact on clinical practice. Summarize research on neurologic-associated dementia. Recognize, diagnose, and manage various neurologic disorders including syncope,movement disorders, normal pressure hydrocephalus, sleep disorders, and CNSinfections. Describe the evidence supporting the clinical use of high-frequency focused ultrasoundto treat tremors.

FacultyCleveland Clinic Course Co-DirectorsGlen Stevens, DO, PhD, FAANRobert Marquardt, DOSection Head, Adult Neuro-OncologyRose Ella Burkhardt Brain Tumor andNeuro-Oncology CenterNeurological InstituteClinical Assistant Professor,Cleveland Clinic Lerner College of Medicineof Case Western Reserve UniversityStaff, Neuromuscular CenterNeurological InstituteCleveland Clinic FacultyRobert Bermel, MD, MBAVineet Punia, MD, MSAssociate Professor, Cleveland Clinic LernerCollege of Medicine of Case Western ReserveUniversityDirector, Mellen Center for Multiple SclerosisNeurological InstituteClinical Assistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityAssociate Staff, Epilepsy CenterNeurological InstituteA. Blake Buletko, MDPayal Patel Soni, MDAssistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityStaff, Cerebrovascular CenterNeurological InstituteBenjamin Claytor, MDAssistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityStaff, Neuromuscular CenterNeurological InstituteCarlos Isada, MDClinical Assistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityDepartment Vice Chair, Infectious DiseaseMedicine InstituteReena Mehra, MDProfessor, Cleveland Clinic LernerCollege of Medicine of Case Western ReserveUniversityDirector, Sleep Disorders ResearchNeurologic InstituteSean Nagel, MDClinical Assistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityStaff, Center for Neuro-RestorationNeurological InstituteBenjamin Walter, MD, MBAAssociate Professor, Cleveland Clinic LernerCollege of Medicine of Case Western ReserveUniversityStaff, Center for Neuro-RestorationNeurological InstituteDylan Wint, MDClinical Assistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityDirector, Lou Ruvo Center for Brain Health NevadaNeurological InstituteJenny Wu, MDClinical Assistant Professor, Cleveland ClinicLerner College of Medicine of Case WesternReserve UniversityAssociate Staff, Diagnostic RadiologyImaging InstituteAssistant Professor, Cleveland Clinic LernerCollege of Medicine of Case Western ReserveUniversityStaff, Center for Neuro-RestorationNeurological InstitutePlanning CommitteeSusan Jakubek, MPAS, MBA, PA-CRose Ella Burkhardt Brain Tumor andNeuro-Oncology Center Neurological InstituteTara Miller, MSN, APRN-CNPRose Ella Burkhardt Brain Tumor andNeuro-Oncology Center Neurological Institute

AgendaFriday, August 5, 2022 Eastern Time7:00 amRegistration/Continental Breakfast/Exhibits/SAE Paper Pre-Test8:00 amIntroduction – Glen Stevens & Robert Marquardt – SALON I8:10 amAcute Stroke Updates: An Ever-Expanding Window of OpportunitiesA. Blake Buletko8:50 amStroke Cases – A. Blake Buletko9:10 amNeurological Approach to Syncope – Robert Marquardt9:50 amRefreshment Break & Exhibits10:10 amNeuroradiology: Brain – Jenny Wu10:50 amNeuroradiology: Spine – Jenny Wu11:30 amHistorical Vignette and Panel Discussion/Q&AGlen Stevens, Robert Marquardt, A. Blake Buletko, Jenny Wu12:00 pmBuffet Lunch – SALON II1:00 pmEpilepsy: Review of Newer Anti-Seizure Medications (ASMs)Vineet Punia1:50 pmEpilepsy Cases – Vineet Punia2:30 pmEpilepsy Q&A – Vineet Punia2:40 pmRefreshment Break & Exhibits3:00 pmNeuro Jeopardy – Glen Stevens and Robert Marquardt4:05 pmAdjournABPN Self-AssessmentThe American Board of Psychiatry and Neurology has reviewed the 2022 NeurologyUpdate – A Comprehensive Review for the Clinician and has approved this program aspart of a comprehensive Self-Assessment Program which is mandated by the ABMSas a necessary component of maintenance of certification. Approved for 17 Category1 CME credits for Self-Assessment.You will be sent a PDF of the pre-test via email prior to the course to complete asyour self-assessment. The answers to the test questions will be addressed duringthe lectures using the Audience Response/Polling System.

AgendaSaturday, August 6, 2022 Eastern Time7:30 amRegistration/Continental Breakfast/ExhibitsInteractive Case-based Breakout SessionsIn-person attendees will be assigned to a room and the speakers will rotate through discussingeach topic below.Topics:Neuromuscular EMG Cases – Benjamin ClaytorHeadache Management Cases – Payal Patel SoniMovement Disorders Management Cases – Benjamin Walter8:00 amBreakout Session Introductions – General Session RoomSALON I – Glen Stevens & Robert Marquardt8:10 amBreakout Session 19:10 amBreakout Session 210:10 amRefreshment Break10:30 amBreakout Session 311:30 amAudience Response / Questions & Answers from Breakout SessionsSALON I – Benjamin Claytor, Payal Patel Soni, Benjamin Walter11:50 amBuffet Lunch – SALON III12:50 pmDementia Update – Dylan Wint1:30 pmDementia Cases – Dylan Wint2:10 pmRefreshment Break & Exhibits2:30 pmMultiple Sclerosis Management – Robert Bermel3:10 pmMultiple Sclerosis and Mimics: Cases – Robert Bermel3:50 pmHistorical Vignette and Panel Discussion/Q&AGlen Stevens, Robert Marquardt, Dylan Wint, Robert Bermel4:20 pmAdjournSunday, August 7, 2022 Eastern Time7:30 amRegistration/Continental Breakfast/Exhibits8:00 amNeurology Consult Cases – Glen Stevens8:40 amSleep Disorders – Reena Mehra9:20 amCNS Infections – Carlos Isada10:00 amRefreshment Break & Exhibits10:20 amNormal Pressure Hydrocephalus – Sean Nagel11:00 amHigh Frequency Focused Ultrasound Use in Tremor – Sean Nagel11:40 amHistorical Vignette and Panel Discussion/Q&AGlen Stevens, Robert Marquardt, Reena Mehra, Carlos Isada, Sean Nagel12:00 pmAdjourn

General InformationLocationThe Ritz-Carlton, Washington DC1150 22nd Street, NW Washington, DC 20037Phone: 202.835.0500Hotel AccommodationsA block of rooms has been reserved at The Ritz-Carlton, Washington DC. To make yourreservation, contact the hotel directly at 202.835.0500 or 1.800.558.9994 and mentionthe “Cleveland Clinic Neurology Update” to receive the special rate of 275 per night plustax. You may also make your reservation online at www.ritzcarlton.com using code CCFCCFA(Single) or CCFCCFD (Double). To secure the course rate, you must make your reservation byMonday, July 11, 2022.The Ritz-Carlton is: 40 minutes east of Dulles International Airport 10 minutes (4.2 miles) north of Ronald Reagan Washington National Airport 10 minutes from the White House, the Smithsonian museums and many other historic siteParkingDiscounted parking is available at The Ritz-Carlton, Washington DC for a special course rateof 40.00 for overnight valet and 30.00 for day valet parking (up to 12 hours).A self-parking garage is also available at the hotel and rates vary.InformationFor further information about this activity, contact Shana Spade at Phone: 216.444.9380 or800.223.2273 x49380 Email: spades@ccf.orgFaculty Disclosure StatementThe Cleveland Clinic Foundation Center for Continuing Education has implemented a policyto comply with the current Accreditation Council for Continuing Medical Education Standardsfor Integrity and Independence requiring mitigation of all faculty conflicts of interest. Facultydeclaring a relevant financial relationship will be identified in the activity syllabus.Americans with Disabilities ActThe Cleveland Clinic Foundation Center for Continuing Education fully intends to comply withthe legal requirements of the Americans with Disabilities Act. If you need assistance, pleasenotify Shana Spade at 216.444.9380 or spades@ccf.org at least two weeks prior to theactivity.Faculty PresentationsFaculty presentation slides will be available online in PDF format. You will have access priorto the activity to allow you to download or print the slides.Health & SafetyAll applicable Centers for Disease Control (CDC), state, and local safety protocols will beenforced for this event. Additional attendance requirements may be implemented to ensureattendee health and safety.