Nutrigenetics, Nutrigenomics And Precision Nutrition

Transcription

Nutrigenetics, Nutrigenomicsand Precision NutritionV. Saroja Voruganti, PhDAssistant ProfessorDepartment of NutritionNutrition Research Institute

UNC NUTRITION RESEARCHINSTITUTEin Kannapolis, North CarolinaOn a 350 acre campus thatfocuses on nutritionresearch.At the NRI we study –Why do metabolism,nutrition and diseaserisk differ betweenpeople?

NORTH CAROLINA RESEARCH CAMPUSMission: To transform science at the intersection of human health,nutrition and agriculture Appalachian State University Human Performance LaboratoryDavid H. Murdock Research InstituteDuke Clinical and Translational Science InstituteNC A&T University Center for Excellence in Post-HarvestTechnologiesNC Central University Nutrition Research ProgramNC State University Plants for Human Health InstituteUNC Chapel Hill Nutrition Research InstituteUNC Charlotte Bioinformatics Services DivisionUNC Greensboro Center for Translational Biomedical Research

NRI RESEARCH INTERESTS We are pioneering research with cutting-edgediscoveries of unique differences in DNA andmetabolism Nutritional individuality through nutrigenomics andmetabolomics. Potential for creating diet and exercise planscustomized to each person’s distinct needs. NRI research is contributing to improved braindevelopment and function, and resistance to or bettertreatment of diseases such as cancer, diabetes, obesitycardiovascular and kidney diseases.

WE EAT VERY DIFFERENTLY, ITMAKES SENSE THAT WE DIFFERIN OUR METABOLISMS

WHY DO METABOLISM, NUTRITIONAND DISEASE RISK DIFFERBETWEEN PEOPLE?Single nucleotidepolymorphism (SNP)GENETIC VARIATIONMany of us have mistakes in ourgenetic code.SNPs are mistakes that occur inat least 1% of the population.It is estimated that each of ushas 50,000 such gene mistakes.

Nutrigenetics, Nutrigenomicsand Precision Nutrition

Nutrigenetics, Nutrigenomicsand Precision Nutrition

Nutrigenetics, Nutrigenomicsand Precision Nutrition

Nutrigenetics, Nutrigenomicsand Precision Nutrition

We would like to thank oursponsors, The Coca-Cola Companyand Dole Foods, for their financialsupport of this short coursewww.uncnri.orgsaroja@unc.edu500 LAUREATE WAYKANNAPOLIS, NC 28081WWW.UNCNRI.ORG704-250-5000

Files in the flash drive GeneticData Info- SNP DetailedInfo- SNPlist NGx2017 WorkshopMaterials- Group1- NRI workshop CYP1A2 HapMap- PONG flyer- Group2- Data files (NGphen.txt, NGped.txt, NGcov.txt, NGmap.txt)- PLINKforNGxWKSHP Instructions2017- WorkshopMaterial Group2 Part1- WorkshopMaterial Group2 Part2 NGx17 HumanCore FinalReport 48

PLINKIf PC type cmd in the search and a terminal will open cd (change directory) to the folder where youhave your files. plink --nowebIf Mac open the terminal cd (change directory) to the folder where youhave your files ./plink --noweb

CHECK WHETHER PLINK ISINSTALLED ON YOUR COMPUTERIf you don’t see this message, it means that PLINK isnot properly installed. Please see Mr. Scott Jaworski

01.05.2017 · and Precision Nutrition. Nutrigenetics, Nutrigenomics and Precision Nutrition. WWW.UNCNRI.ORG 704-250-5000 500 LAUREATE WAY KANNAPOLIS, NC 28081 www.uncnri.org saroja@unc.edu We would like to thank our sponsors, The Coca-Cola Company and Dole Foods, for their financial support of this short course Genetic Data Info - SNP_DetailedInfo - SNPlist_NGx2017