RETIRED MEN'S ASSOCIATION Cigar Box Bulletin V 24 I

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RETIRED MEN’S AS SOCI ATIONCigar Box BulletinV O LUME 24 I SSUE 8A U GUST 2020Genetic Enhancement / Therapy:Altering Ourselves and/or Our ProgenyDr. Harold T. ShapiroProfessor of Economics and Public Affairs at the Woodrow Wilson School at Princeton UniversityReporter: Bill BeebeeBorn and raised in Montreal and graduated from McGill U., Dr. Shapiro later earned his PhD in Economics atPrinceton in 1964. He then joined the U. ofMichigan faculty as an assistant professor ofeconomics, eventually becoming EconomicsChairman. By 1980, he had been appointedPresident, there, where he stayed until joiningPrinceton as President in 1988. He was elected Fellow of the American Academy of Artsand Sciences two years later. Retiring in2001, Dr. Shapiro is a professor emeritus ineconomics and public policy at Princeton. Heis a trustee emeritus at the local Institute forAdvanced Study. He writes extensively onbioethics. He chaired the National BioethicsAdvisory Commission for the White House inthe 1996-2000 Presidential Term.Darwin gave his theory of evolution. He described an ongoing process, starting with bacteria (beginning 4 billion years ago) and carrying through humans (starting 250,000 yearsago). The process, which he called NaturalSelection, showed species descended fromtheir ancestors with changes due to environmental influences. Beyond general curiosityon the natural evolution, some people wantedto systematically modify environmental influences to try to control human evolution. Theclaim was that controlling the evolution ofhumans would be a force for good.I N S I D E T HI S IS S UE :In the 19th Century, cells were understood asthe building blocks of life. By the early1950's, the mechanism controlling cellgrowth began to be known. The dual-helixDNA molecule was identified as guiding theLeading up to this treatment of the ethics offoundation and growth of cells that make upmodern genetics, Dr. Shapiro surveyed genet- living bodies. This study effort led to theics research over the past 170 years. In 1859, understanding of how to alter the cell DNA toContinued on Page 2August Meeting MinutesShip’s Bell Rang at 10:00 AMChris Hammer called the August 13meeting to order, allowing for members joining the Zoom session(including later entries).Chris thanked the following Members fortheir contributions to the Meeting:Reporting on the Minutes - Bill BeebeeReporting on the Speaker - Bill BeebeeReporter: Bill BeebeeBulletin - Bob Diefenbacher (Chris thankedBob for publishing both bulletins and minibulletins, doing a GREAT JOB.)Slide Show - Don ShermanWebsite - Ken MattesMembers Support Help Line - Al PerssonChris Hammer said that the RMA helpedthe kids of Merrill and Nancy Mack to celeContinued on Page 3U P C O MIN GZ O O M M E E T IN G S

C IGAR B OX B U LLE T INP AGE 2Speaker — Continuedultimately change these bodies. This research area is calledMedical Genetics. The twin impulses for developing Med- Sometimes getting into the Pro Life / Pro Choice debate:ical Genetics were 1) relief of suffering and 2) human improvement."Is it immoral for a couple to avoid having a disabledchild?"The downside of the opportunity for significant change isthat it can cause societal anxiety, often expressed in contemporary popular literature. Matthew Arnold's 1867 nov- Theologically, is altering genes "Playing God"? Is the natel Dover Beach told of some being able to retreat into "the ural genetic lottery an inherent part of "God's Plan"? Ischance intrinsic in what it means to be human? Is it moralgood old days" of a private life. The theme of "scienceplaying bad" was seen in Mary Shelley's novel Frankenly acceptable to alter one's traits?stein. Huxley's novel Brave New World talked about Eugenics, applied with racism to achieve very negative results. (Reporter's clarification: Eugenics is a set of beliefs What about disease? Should genetic testing be used to IDcurrently untreatable diseases? Do carriers of currentlyand practices intended to improve the quality of a humanpopulation, excluding supposed inferior groups (forbidding untreatable diseases have an obligation to avoid pregnansome marriages and using selective forced sterilization) to cy?allow supposedly-superior groups to prosper.)Is it morally acceptable to test embryos and discard undeT.S. Eliot produced the words for a 1934 play called TheRock. These words, called Choruses from the Rock, were sirable ones (use of Preimplantation Genetic Diagnosispublished as a poem in a book of his poetry. In the poem, (PGD))? Could the past-maligned Eugenics come back?Eliot decries too much technology progress without theknowledge coming from inner stillness. He says "we needActually, Eugenics is back, and it is out of the closet (butwisdom and ethical guidance as we proceed forwards."without some of the revulsions of the past). PopulationsThis year, Robert Pensky wrote the think piece Beachare not exterminated (as the Nazis so horrifically emGlass in The New Yorker. He decries making large numbers of plastic bottles containing clean drinking water, but ployed) and marriage-banning or forced sterilization is notused (as was followed in supposedly civilized countrieswith those bottles ending up in huge pollution formationslike the UK and US). Now, the genes, themselves, arein the World's oceans.transformed much of the time. Improved athletics performance is a sometime-goal. In-vitro fertilization (IVF) hasWith the speed of Genetic Engineering developments, are become commonplace. Before the fertilization, the eggsand sperm are operated on to adjust their genetic codes.we presented with a boundary (moral or otherwise) thecrossing of which is a "step too far"? What is Genetic En- This is called germline editing. Unfortunately, it is not assuccessful as the above-noted PGD, which destroys embrygineering / Genetic Therapy? There is a difference between the Therapy (curing something) and the Engineering os.(making something better). Do we want to cure a disease,or to enhance ourselves and our progeny, or to achieveModern Eugenics is the dream of control over human fateboth?and chance. Who can disagree with the treatment of disease and the enrichment of human beings? Who can disagree with reducing human suffering and the improvementGenetic Engineering / Therapy is the emerging ability tochange our DNA and the inheritance of our progeny. The of human beings?Ethics Question is:"Is gene therapy moral if it is designed to ensure or restorenormal functions but immoral if it is aimed at enhancingfunctions beyond normal?"What is wrong with this dream? Here are three criticismsto remember:If this dream does not also in-Continued on Page 9

V O LUME 24 I SSUE 8P AGE 3Minutes—Continuedbrate the Mack's 60th Wedding Anniversary. Those kidssent the RMA a nice Thank You note:"We send you our deepest appreciation and heartfeltthanks for your role in making our parents' anniversarycelebration one of fun, fellowship, music, and song. Theirday was filled with love, laughter, and surprises and exceeded our expectations on every level.Dance this year. MA Gov. Charlie Baker says that nomeeting will be allowed to have more than 50 attendees.The Spring of 2021 may be another opportunity. TheRMA Board will Zoom Meet in September to try to finalize these plans.Chris mentioned the Discussion Group, which will meetvia Zoom at noon on Wed., August 19. The meeting willselect the topic (have suggestions ready). Let Chris knowWith Gratitude, Linda, Richard, and Sarah"if you will attend, and he will send the link and instrucChris announced the passing of William (Bill) Buckley on tions. His e-mail address is chammer6060@gmail.com7/1/20. His family thanked the RMA for our memorialDon Sherman announced the Birthdays and Anniversariesdonation.for August. Oldest-birthday honor is 91 years young,Chris said that at this time, we plan to hold Zoom meetshared by Peter Beckwith and Bert Sellier. Oldestings for the remainder of 2020. The Next Zoom meetinganniversary belongs to Gail and Derena Drake, still inwill be September 11 at 10 AM. The topic will be "Alove after 70 years.Race to Remember" and the Speaker (speaking live) willChris Hammer told of the Health of Our Members. Mortbe Larry Kerpelman of the American History Magazine.Brond is at the Willows in Southborough. He had aorticThe October Speaker visit is close to being arranged.surgery about a month ago. He is in rehab and is recoverChris noted that there will likely be no Annual Dinnering. However, he sounded tired and somewhat discourContinued on Page 4The Cigar Box BulletinP. O. Box 261Wayland, MA 01778Board of DirectorsChris HammerPresidentLarry Vifquain1st Vice PresidentTBD2nd Vice-PresidentMerrill MackTreasurerChris HammerProgram ChairmanBob DiefenbacherEditor of BulletinBoard MembersRay Atkins*Bob DiefenbacherChris HammerBob MalnatiRon RiggertPaul SturgisLarry Vifquain*Past RMA PresidentsBill BeebeeBill Ely*Merrill MackAl Persson*Richard G. SmithNick VeederEmeritus MembersMorton BrondWayne Clemens*Barry DavidKarl GeigerJohn Kiladis,Frank Lyons*Thank You To Our Proof Readers:Yutaka Kobayashi,Stan WulfAnd to Our Photographer:John McKinneyPublished monthly by the RetiredMen’s Association of Weston,Wayland, Sudbury andsurrounding communities.

V O LUME 24 I SSUE 8P AGE 4Letter from RMA President Chris Hammer—Hi all,Hope all are safe and enjoying time with your family and friends, I am and it is fun, especially the grandkids.Our first regular RMA meeting (Thursday, August 13, 2020) held over Zoom went smoothly. There were 31 attendees and 2 whothought it was Friday.Our next RMA meeting will be Friday, September 11 at 10:00 am. The Zoom link and sign on information will be sent to all about aweek prior to the meeting. Block out the date so you can join us.If you have questions about signing onto Zoom, check the RMA website, there is a written document explaining how to do it and avideo explaining Zoom sign on.CHALLENGE – if you attended the August meeting; contact an RMA friend and getthem to join all of us at the September meeting or invite a friend.If you missed the August meeting, join us in September.The live speaker will be – Larry Kerpelman; Topic: “A Race to Remember”Larry Kerpelman's writing and editing reflects both his widely varied personal interests and his educational background. His work hasappeared in a variety of popular publications, such as The Boston Globe, The Boston Globe Magazine, HealthWorks magazine, andGreen Prints magazine, as well as in professional journals, among them The Journal of the American Medical Association, Physicians News Digest, The Chronicle of Higher Education, and Journal of Counseling Psychology.Race to RememberGunplay at Lexington and Concord had rebels and British general Thomas Gage in competition to spin the story for the worldFor your planning; all of the RMA meetings in 2020 will be held via Zoom. Consider joining your friends at the Zoom RMA meetings.If you have questions and want to try to sign on to Zoom prior to the meeting give me a call and I will work with you – 978 239-6764Join the fun.Best,Chris HammerMinutes, Continued—aged because the recovery has been slow. Mort wouldappreciate phone calls. He can be reached at (508) 2127599.Chris also noted that Ron Riggert is recovering from eyesurgery.Humor was provided by Nick Veeder. A neighbor of hissaw another neighbor having a long, in-depth conversa-tion with his cat. The observing neighbor thought that soremarkable that he related the details of what was said tohis own dog. (Bob Diefenbacher will receive more humor, for the Bulletin, from Harold Wilkinson.)Our Speaker, Dr. Harold Shapiro, speaks to us via a recorded address previously given to the RMA in Greenwich, CT. (This RMA, started years before ours, is

C IGAR B OX B U LLE T INP AGE 5From Harold Wilkinson.RMA Jokes for August, 2020 Who said “Old dogs can’t learn new tricks?” This group of “old dogs” seems to havemastered the new world of electronics & Zoom!Bill Beebee: Zingers from Phyllis Diller:Whatever you may look like, marry a man your own age. As your beauty fades, so will his eyesight.Housework can't kill you, but why take a chance?Best way to get rid of kitchen odors: Eat out.I want my children to have all the things I couldn't afford. Then I want to move in with them.We spend the first twelve months of our children's lives teaching them to walk and talk and the next twelve years tellingthem to sit down and shut up.My photographs don't do me justice – they look just like me.You know you're old if they have discontinued your blood type.Al Persson: The Korean War, in which the US Marine Corps fought some of its most brutal battles, was not without itsgallows humor:During one such conflict an ROK (Republic of Korea) commander, whose unit was fighting along with the Marines,called legendary Marine General Chesty Puller, to report a major Chinese attack in his sector."How many Chinese are attacking you?" asked Puller."Many, many, many, many, many Chinese!" replied the excited Korean Officer.General Puller asked for another count and got the same answer, "Many, many, many, many Chinese!""Dammit!" swore Puller, "Put my Marine Liaison Officer on the radio."In a minute, an American voice came over the air: "Yes Sir?""Lieutenant," growled Chesty, "Exactly how many Chinese you got up there?""General, we've got a whole shitload of Chinese up here!"Thank God!" exclaimed Puller, "At least there's someone up there who knows how to count!"Iberg: Witty double entendre’sThe meaning of opaque is unclear.I'm reading a book about anti-gravity. I can't put it down.It's not that the man couldn't juggle - he just didn't have the balls to do it.So what if I don't know the meaning of the word “apocalypse”! It's not the end of the world.Police were called to the daycare center. A 3-year old was resisting a rest.Did you know they won't be making yardsticks any longer?A relief map shows where the restrooms are.Iberg: Wine TasterIn a wine factory the regular taster died and they were looking for a new one. A ragged, dirty drunkard came to apply forthe position. The director was about to send him away, but first they tested him. They gave him a glass of wine. He triedit and said, “It's red wine, a Muscat, three years old, grown on a north slope, matured in steel containers.”"That's correct", said the boss.Continued on Page 6

V O LUME 24 I SSUE 8P AGE 6Securely erase your data with Active@ ZDeleteDid you know that the normal way of deleting datadoesn't actually remove the files? This mightsound strange, given how you usually receive sucha warning before you empty the recycle bin or format adrive. But everything you delete can be recovered usingspecialized software. It's very important that you know thisif you're planning to sell or donate your old computer orany other digital storage device. In such cases, data whichyou thought you deleted can easily end up in the wronghands. Often, when you delete something, you're sure youwill never need it again. That's fine, but if the files containany sensitive information, the last thing you want is forsomeone else to get their hands on it.Active@ ZDelete helps you overcome this problem freelyand easily. Firstly, however, it's important to understandhow modern digital storage devices work. When you deletefiles and folders in the normal way, such as emptying therecycle bin or formatting a drive or volume, nothing is really deleted. Instead, the disk sectors which were previouslyoccupied by the file are made available to the operatingsystem. The files appear to be gone, but they're really stillthere on the disk until something else overwrites it. Thiscan happen at any time but, until it does, the data can berecovered. The only thing that changes during the normaldeletion process is an entry in the master file table.The only way to properly delete data so that it may neverbe recovered is to ensure it gets overwritten by somethingelse. Sometimes, this can take many months or even years.It mostly depends on how often you use the drive and howfrequently you write new data to it. You can't rely on gen-eral use to overwrite the files. Active@ ZDelete overcomesthis limitation by giving you a simple alternative to the recycle bin. Enter the ZDelete Bin, which provides a comfortable and familiar experience much like the normal recycle bin. Only, when you drag and drop a file or folder intoit, that data is gone for good. It's overwritten with zerosaccording to the internationally recognized US Departmentof Defense 5220.22-M standard.When you use Active@ ZDelete by dragging and droppinga file, a dialog box will appear providing further options.You can choose from various erasure and wiping methods,including one or multiple passes of zeros. For example, onepass overwrites the deleted data with zeros. Even then, inextreme cases, the data might still be recoverable, especially if you're using a magnetic storage device like a conventional hard disk. Fortunately, you can also choose evenmore secure wiping methods, including multiple passes ofzeros. Using the ZDelete alternative to the recycle bin, youcan simply delete files the normal way too. However, whenyou empty the bin, it will ask you if and how you want tooverwrite the data.Active@ ZDelete is now fully freeware, and you no longerneed to register to use any of the erasure methods. The diskwipe procedures have also been improved for certain filesystems, alongside various minor improvements and bugfixes. Download today at https://www.zdelete.com/index.html .By George G. Johnson, who works in a large data centerwhere obsolete information needs to be securely deletedwithout any possibility of recovery.Continued from Page 5Another glass. "It's red wine, cabernet, eight years old, a southwestern slope, oak barrels.""Correct."The director was astonished. He winked at his secretary so she brought in a glass of urine.The alcoholic tried it. " It's a blond, 26 years old, pregnant in the third month. And if you don't give me the job, I'll alsoname the father".Beebee: General Norman Schwarzkopf was asked if he thought there was room for forgiveness for the people who harbored and abetted the terrorists who perpetrated the 9/11 attacks on America. His answer was classic Schwarzkopf. The General said, "I believe that forgiving them is God's function. It’s OUR job to arrange the meeting."

C IGAR B OX B U LLE T INP AGE 7Anniversaries in lliam Diana08/03/196357Alfred 664Norman E.SearsDorothy08/07/195565Robert /11/195169Gail V.DrakeDerena A.08/06/195070Average Years Married—56

V O LUME 24 I SSUE 8P AGE 8Birthdays in th08/05/192991BertSellier08/13/192991Average Age— 84Happy Birthday

C IGAR B OX B U LLE T INP AGE 9Speaker, Continued—corporate the impulse to improve the current condition oflife, it is impoverishing.We choose to explain human nature in terms of heredity,because it promises a technological solution to our problems which seems easier than pursuing social/political solutions.Its great risk is that it obscures the power of diversity, thebeauty of chance, and the virtues of tolerance by illusionsof (technological) perfectibility.adapt to unknown future calamities. Since humans survive by helping each other, a calamity can be overcome bythose adapted to it cooperating with others (less-adapted)to make sure that the group as a whole comes through it.Without diversity in the group to deal with a wide varietyof problems, the group as a whole is less likely to survive.By choosing our genetics, we accept the risk of ruling outdiverse survival characteristics that might save us in unknown futures.)(Reporter's appreciation: Ken Mattes provided repeatedand essential help in getting the Speaker's input into useable form so that this Report could actually be written.)(Reporter's opinion: a great virtue of diversity for humansurvival is that a wide selection of human characteristicsallows a greater chance that some humans will successfullyA Corona Virus Article.Hi alleral days. Only later does it the immune system find theintrusive virus, resulting in symptoms finally showing ofCOVID-19. This is unique among viral infections. This iswhy so many infected carriers are so asymptomatic!!A friend sent me a very interesting article from ScientificAmerica about the Corona -19 virus. If you are interested ingetting a look into the virus’ complexity, open the link beIt also has "intelligence" to autocorrect its own DNA stringlow.if it is mutated. This makes it very tough to kill.I thought this article was outstanding, almost too technical,but not really.Note that the COVID virus amazing DNA strain allows itto initially hide itself from our body's immune system sothat it can quickly replicate itself in our lungs, etc. for sev-What scientists know about the inner workings of the pathogen that has infected the -visual-guideto-the-sars-cov-2-coronavirus/Knock Knocks for your grandchildren.Knock knock. Who's there? Hawaii. Hawaii who? I'm fine, Hawaii you?Knock knock. Who's there? Nana. Nana who? Nana your business.Knock knock. Who's there? Hatch. Hatch who? God bless you.Knock knock. Who's there? Mustache. Mustache who? Mustache you a question, but I'll shave it for laterKnock knock. Who's there? Amish. Amish who? Really? You don't look like a shoe.Knock knock. Who's there? Gorilla. Gorilla who? Gorilla me a hamburger.—Chris

V O LUME 24 I SSUE 8P AGE 1 0RMA Bulletin BoardRiddlesfor Your Grandchildren.Double my numberI’m less than a scoreHalf of my numberIs less than four SIXGoes up and down the stairsWithout ever moving CARPETSome men lose itWhen they get oldA shiny sight to behold HAIRYou throw this outWhen you want to use itBut take it inWhen you no longer need it - ANCHORCartoons From The New YorkerIf you change your email address, be sure to let Ron Riggert know so youcontinue to receive RMA emails. Ron’s email is: rkriggert@verizon.net

P AGE 1 1C IGAR B OX B U LLE T INKing James IQueen Elizabeth I of England, the virgin queen, died in 1603. She left no heir. Therefore, King JamesVI of Scotland, her nearest relative, became King of England and Ireland. He also remained king of Scotland.He was the first king of the British Isles and was known as James I.James I, was highly educated and encouraged the education of those in his realm. He urged the study ofscience, literature and the arts.He, like many others of his day, believed in witchcraft. He wrote several essays on the subject. Themost famous is “Daemonologie,” a treatise on sorcery and witchcraft.Shakespeare used material from “Daemonologie” in writing Macbeth and Hamlet.In 1604, James I wrote “A Counterblast to Tobacco,” in which he states that the use of tobacco is offensive to others and very harmful to the liver, heart and lungs of the user.The tobacco James I was talking about in his thesis was grown in Toledo, Spain, from seeds broughtfrom Mexico by Hernandez de Boncalo.Jamestown, Virginia, founded on May 4, 1607, was the first permanent settlement in North America. Itwas named in honor of James I, who granted the charter to the Virginia Company of London.The natives of America had grown tobacco for years. They used tobacco in rituals and not for generalrelaxation.When Jamestown was founded, tobacco had become very popular in England. From the very beginningof Jamestown, tobacco was the main cash crop. Because of his aversion to tobacco, James I leveled a hefty import tax on tobacco imported into England.The import tax had little effect on the use of tobacco. In the 1600s and later, tobacco was smoked usingvarious pipes.On November 5, 1605, a group of Catholics were planning to blow up the House of Parliament whenJames I was in the building attending a ceremony. One of the conspirators, Guy Fawkes, was discovered in thebasement with barrels of gun powder. The incident is known today as the Gunpowder Plot and Guy Fawkesday is celebrated every November 5 by the lighting of bonfires or fireworks.James I did not write, but authorized the translation of the King James Bible from the Greek and Latin.One of the problems the translators encountered was the lack of English words to express concepts in the Bible. They often created new words to capture the correct meaning.At the time, most of the educated class in England was bilingual. They spoke both English and French.French words often appeared in the translations and later in everyday use by those with little or no formal education.It is similar to the introduction of new words to express new concepts and procedures into the moderncomputer world.

First Class MailNext MeetingFriday, September 11, 2020Web site RMenA.orgE-mail info@RmenA.orgR.M.A.Box 261Wayland, MA 01778Next RMA Meeting: Friday, September 11 10:00 am via ZoomLarry Kerpelman; Topic: “A Race to RememberA Live Presentation—Larry Kerpelman's writing and editing reflects both his widely varied personal interests and his educationalbackground. His work has appeared in a variety of popular publications, such as The Boston Globe, The Boston Globe Magazine, HealthWorks magazine, and Green Prints magazine, as well as in professional journals,among them The Journal of the American Medical Association, Physicians News Digest, The Chronicle ofHigher Education, and Journal of Counseling Psychology.Zoom address link will be sent about a week before the meeting. Watch your email!Invite a Guest to our September 11 Zoom Meeting !

Professor of Economics and Public Affairs at the Woodrow Wilson School at Princeton University UPCOMING ZOOM MEETINGS VOLUME 24 ISSUE 8 Cigar Box Bulletin AUGUST 2020 RETIRED MEN'S ASSOCIATION B orn and raised in Montreal and gradu-ated from McGill U., Dr. Shapiro lat-er earned his PhD in Economics at Princeton in 1964. He then joined the U. of