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Continuing Medical Education10524 Euclid Ave.Cleveland, Ohio 44106C O N T I N U I N G M E D I C A L E D U C AT I O NPRESENTED IN COOPERATION WITH THE CLEVELANDSOCIETY OF RHEUMATOLOGY31st Annual ClevelandReview of Rheumatic Diseases / CID2745A Comprehensive Review of Emerging andControversial Topics in RheumatologyFRIDAY AND SATURDAYMAY 20-21, 2022TINKHAM VEALECLEVELAND, OHIOPRESENTED BYTHE DIVISION OF RHEUMATOLOGY, DEPARTMENTOF MEDICINEUH CLEVELAND MEDICAL CENTERPRESENTED BY:SPONSORED BY:

ABOUT THE SYMPOSIUMTARGET AUDIENCEThis Symposium provides a comprehensive, state-of-the-art review of the latest advances in diagnosisand management of rheumatic diseases. It will be of interest not only to rheumatologists, but also toprimary care physicians, Rheumatology fellows and nurses. Allied health professionals will also benefitfrom this symposium.LEARNING OBJECTIVESAt the conclusion of this symposium, participants will be able to: Strategize therapies in psoriatic arthritis and axial spondyloarthritis patients that have been onchronic biologic treatment Discuss treatment of scleroderma, systemic lupus erythematosus osteoarthritis, inflammatorymyopathy and osteoporosis incorporating recent advances in the therapy Identify recent advances in the pathogenesis of axial spondyloarthritis Describe the newer guidelines for management of psoriatic arthritis and emerging treatments foraxial spondyloarthritis Teach the management of chronic rheumatic manifestations in patients that are infected withSARS CoV-2 (COVID long haulers) Demonstrate the need to prioritize vaccines in patients on immunosuppressive treatments Explain the management of immunosuppressive medications during perioperative period Report on the impact of COVID-19 infection on the immune system Manage patients with newer options in osteoporosisSYMPOSIUM COMMITTEEMarina Magrey, MD, ChairmanDavid Blumenthal, MD, Co-DirectorAli Askari, MDLawrence Kent, MDMaya Matter, MDOgechi Muoh, MDElizabeth Roter, MDVan Warren, MDEDUCATIONAL DESIGNDidactic lectures incorporate 15-minute question and answer sessions. Case studies will be presentedto address patient management issues. Audio/visual support will enhance the learning process.CONTINUING EDUCATIONCase Western Reserve University School of Medicine is accredited by the Accreditation Council forContinuing Medical Education to provide continuing medical education for physicians.Case Western Reserve University School of Medicine designates this live activity for a maximum of10.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with theextent of their participation in the activity.

PROGRAM AGENDA31st Annual Cleveland Review of Rheumatic DiseasesTinkham Veale, Cleveland, OHFriday, May 20, 20227:00 – 7:55 a.m.8:00 – 8:05 a.m.Registration, Exhibit Hall and Continental BreakfastWelcome and IntroductionMarina Magrey, MDSession I: Recent Advances in Pathogenesis and Therapeutics in Rheumatic DiseasesModerators: Ali Askari, MD and Elisabeth Roter, MD8:05 – 8:40 a.m.Pathogenesis of Axial Spondyloarthritis – Beyond HLA-B27Joerg Ermann, MD8:40 – 9:15 a.m.Strategizing Biologic Therapy in Axial Spondyloarthritis – Time to Taperor DiscontinueAtulya Deodhar, MD9:15 – 9:50 a.m.Inflammatory Myopathy – Recent Advances in TreatmentChester V. Oddis, MD9:50 – 10:10 a.m.Q&A10:10 – 10:30 a.m.Break, Exhibits and Refreshments10:30 – 11:05 a.m.Are the Newer Treatments in Lupus Nephritis Improving Outcomes?Sarfaraz A. Hasni, MD MSc.11:05 – 11:40 a.m.Scleroderma Management – New Treatments In SclerodermaShervin Assassi, MD, MS11:40 a.m. – 12:00 p.m. Q & A12:00 – 1:00 p.m.Lunch Break and Non-CME Industry SymposiumsSession II: Osteoporosis and Osteoarthritis- What is New?Moderators: Van Warren, MD and David Blumenthal, MD1:00 – 1:35 p.m.Beyond Bisphosphonates – What Are The Newer Options In Osteoporosis?Mary Beth Humphrey, MD, PhD1:35 – 2:10 p.m.Osteoarthritis, Do We Have Any Newer Options?Tuhina Neogi, MD, PhD2:10 – 2:45 p.m.Perioperative Medicine – How to Deal with Immunosuppressive Therapy?Susan M. Goodman, MD2:45 – 3:05 p.m.Q&A3:05 – 3:25 p.m.Break, Exhibits and Refreshments3:25 – 4:35 p.m.Diagnostic Dilemmas: Case DiscussionsMuhammad Asim Khan, MD; Maya Mattar, MD and Rula Hajj-Ali, MD4:35 – 5:00 p.m.Q&A5:00 p.m.Non-CME Industry SymposiumsAdjourn for the day

PROGRAM AGENDASaturday, May 21, 20227:30 – 8:00 a.m.Registration, Exhibits and Continental Breakfast8:00 – 8:05 a.m.Opening RemarksMarina Magrey, MDSession III: New Lessons Learned from COVID PandemicModerators: Lawrence Kent, MD and Maya Mattar, MD8:05 – 8:40 a.m.The Impact of Treatment of Rheumatic Disease on HostResponse to COVID and COVID VaccineDonald Anthony, MD8:40 – 9:15 a.m.COVID-19 Long Haulers – How to Manage the Symptoms?Leonard Calabrese, DO9:15 – 9:45 a.m.Vaccines in Immunocompromised PatientsNora G. Singer, MD9:45 – 10:00 a.m.Q&A10:00 – 10:20 a.m.Break, Exhibits and RefreshmentsSession IV: Emerging Guidelines in Management of PsA and ASModerators: Ogechi Muoh, DO10:20 – 10:55 a.m.Newer Guidelines for Treatment of Psoriatic ArthritisM. Elaine Husni MD MPH10:55 – 11:30 a.m.Management of Axial SpAMarina Magrey, MD11:30 – 11:50 a.m.Q&A11:55 a.m. – 12:00 p.m. Closing RemarksMarina Magrey, MDFACULTYUniversity Hospitals of ClevelandDivision of RheumatologyMarina Magrey, MDCourse DirectorProfessor of MedicineCase Western Reserve University School of MedicineChief, Division of RheumatologyUH Cleveland Medical CenterAli Askari, MDProfessor of MedicineCase Western Reserve University School of MedicineUH Cleveland Medical CenterDonald Anthony, MD, PhDSenior Clinician Scientist, US Department ofVeterans AffairsProfessor of Medicine and PathologyDivisions of Rheumatology and Infectious DiseasesMetroHealth Medical CenterVA Northeast Ohio Health Care SystemsCase Western Reserve UniversityDavid Blumenthal, MDAssistant Professor of MedicineCase Western Reserve UniversityDivision of RheumatologyUH Cleveland Medical Center

FACULTY cont.Lawrence Kent, MDClinical Professor of MedicineCase Western Reserve UniversityUniversity Hospitals of ClevelandMuhammad Asim Khan, MD, MACPProfessor Emeritus of MedicineCase Western Reserve University School of MedicineUniversity Hospitals of ClevelandMaya Mattar, MDAssistant Professor of MedicineProgram Director, RheumatologyCase Western Reserve UniversityVA Northeast Ohio Health Care SystemUniversity Hospitals of ClevelandOgechi Muoh, DOClinical Instructor of MedicineCase Western Reserve UniversityRheumatologyUniversity Hospitals of ClevelandElisabeth Roter, MDClinical Assistant Professor of MedicineCase Western Reserve University School of MedicineUniversity Hospitals of ClevelandVan Warren, MDAssistant Professor of MedicineCase Western Reserve University School of MedicineUniversity Hospitals of ClevelandGuest FacultyShervin Assassi, MD, MSProfessorDivision Director, Rheumatology And ClinicalImmunogeneticsThe University of Texas Health Science Center at Houston(UTHealth)Leonard Calabrese, DORheumatologic and Immunologic DiseaseProfessor of MedicineCleveland Clinic Lerner College of Medicine of CaseWestern Reserve UniversityAtulya Deodhar, MD, MRCPProfessor of MedicineDivision of Arthritis and Rheumatic DiseasesOregon Health & Science UniversityJoerg Ermann, MDAssistant Professor of MedicineBrigham and Women’s Hospital andHarvard Medical SchoolSusan M. Goodman, MDRheumatology, Perioperative MedicineAttending Physician, Hospital for SpecialSurgeryProfessor of Clinical Medicine, Weill CornellMedical CollegeRula Hajj-Ali, MDDepartment of Rheumatologic andImmunologic DiseasesCleveland ClinicProfessor of MedicineCleveland Clinic Lerner College of Medicine ofCase Western Reserve UniversitySarfaraz A. Hasni, MD MScChief, Lupus Clinical Trials UnitDirector, Lupus Clinical Research ProgramNational Institute of Arthritis andMusculoskeletal and Skin DiseasesMary Beth Humphrey, MD, PhDAssociate Dean of ResearchProfessor of MedicineMcEldowney Chair in ImmunologyDivision Chief of Rheumatology, Immunologyand AllergyThe University of Oklahoma College ofMedicineM. Elaine Husni MD MPHAssistant ProfessorCleveland Clinic Lerner College of Medicine ofCase Western Reserve University.Vice Chair of RheumatologyDirector, Arthritis and Musculoskeletal CenterOrthopedic and Rheumatologic Institute atCleveland Clinic

FACULTY cont.Tuhina Neogi, MD, PhDProfessor of MedicineBoston University School of Public HealthChief, RheumatologyBoston Medical CenterNora G. Singer, MDProfessorCase Western Reserve University School of MedicineDivision Director of RheumatologyThe MetroHealth SystemChester V. Oddis, MDProfessor of MedicineDirector, Myositis CenterUniversity of Pittsburgh Medical CenterFACULTY DISCLOSUREThe policy of the Case Western Reserve University School of Medicine CME Program (CWRU) requires thatthe Activity Director, planning committee members and all activity faculty (that is, anyone in a positionto control the content of the education activity) disclose to the activity participants all relevant financialrelationships with commercial interests. Disclosure will be made to activity participants prior to thecommencement of the activity. CWRU also requires that faculty make clinical recommendations based onthe best available scientific evidence and that faculty identify any discussion of “off-label” or investigationaluse of pharmaceutical products or medical devices.INFORMATIONMEETING LOCATIONTinkham Veale University Center11038 Bellflower RdCleveland, OH 44106216-368-5681The Tinkham Veale University Center is located in the heart of University Circle. The conference will be heldin the Kelvin & Eleanor Smith Foundation Grand Ballroom on the second floor. Persons with disabilitiesshould inform Tinkham Veale staff of any special services required.PARKINGGuests are encouraged to park in the underground garage located at Campus Center Parking Garage (LotS-29), 11172 East Boulevard, Cleveland, Ohio 44106. You are responsible for your own parking charges.

REGISTRATION INFORMATIONConference tuition includes all educational sessions, materials, refreshments, and continental breakfast eachday. Registration is on a first come basis. Register online at https://bit.ly/RheumaticDisease2022. Advancepayment secures your participation in the program.For additional information contact the CME Program at medcme@case.edu or 216-983-1239.LATE REGISTRATION AND CANCELLATION POLICYPreregistrations are accepted online until 7 a.m. ET Wednesday, May 18, 2022. Full refunds will be madefor cancellations on or prior to May 13 only. A cancellation received after that date requires anadministrative fee of 100.00. Please direct questions to medcme@case.edu.ACKNOWLEDGMENTSThis Symposium will be supported by educational grants from our industry partners. A complete listing ofsupporters will be provided in the educational materials distributed at the program.Acceptance of funding in support of this program does not constitute endorsement of any productor manufacturer.

PRESENTED BY:SPONSORED BY:M AY 2 0 –2 1 , 2 0 2 2CID 274531st Annual Cleveland Review of Rheumatic DiseasesHOWHOW TOTO REGISTERREGISTERRegister on-line at https://bit.ly/RheumaticDisease2022 withwith aa creditcredit card.card.TUITIONCleveland SocietySociety ofof RheumatologyRheumatolgy memberClevelandmemberandandUHUHAlumniAlumni 325 325 225 225Allied Health Professional 175 175Corporate 400 400PhysicianPhysicianResident/Fellowwith letter fromProgramDirectorComplimentary with letter from Program ComplimentaryDirector documentingresidencystatus.* After May 1st, prices increases 50documenting residency status. Email to medcme@case.eduand registration instructions will be sent in response.* After May 1st, prices increase 50Signature 2022 University Hospitals TAY0047 2022 University Hospitals TAY0047

31st Annual Cleveland Review of Rheumatic Diseases / CID2745 A Comprehensive Review of Emerging and Controversial Topics in Rheumatology FRIDAY AND SATURDAY MAY 20-21, 2022 . Orthopedic and Rheumatologic Institute at. Cleveland Clinic. INFORMATION MEETING LOCATION Tinkham Veale University Center 11038 Bellflower Rd Cleveland, OH 44106