The Association Between Variant Rs9939609 In The FTO Gene With Free .

Transcription

011)Rs9939609 variant of the fat mass and obesity-associated gene and trunkobesity in adolescents. J Obes 36:186368Olza J, Ruperez AI, Gil-Campos M, Leis R, Fernandez-Orth D, Tojo R, CañeteR, Gil A, Aguilera CM (2013) Influence of FTO variants on obesity, inflammation, and cardiovascular disease risk biomarkers in Spanish children: acase-control multicentre study. BMC Med Genet 14:1–11Czogala W, Czogala M, Strojny W, Ator GW, Wolkow P, Wojcik M, Multanowski MB, Tomasik P, Edrychowicz AW et al (2021) Methylation andexpression of FTO and plag1 genes in childhood obesity: insight intoanthropometric parameters and glucose-lipid metabolism. Nutrients13:1683Labayen I, Ruiz JR, Ortega FB, Dallongeville J, Jiménez-Pavon D, CastilloMJ, Henauw S, González-Gross M, Bueno G, Molnar D, Kafatos A, DiazLE, Meirhaeghe A, Moreno LA (2011) Association between the FTOrs9939609 polymorphism and leptin in European adolescents: a possiblelink with energy balance control. HELENA Study Int J Obes 35:66–71Andreasen CH, Stender-Petersen KL, Mogensen MS et al (2008) Lowphysical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes 57:95–101Shaheed A, Rana S, Saeed S et al (2013) Common variant of FTO gene,rs9939609, and obesity in Pakistani females. Biomed Res Int 324093:1–7

Lubis e

Applied Biosystems, Foster City, CA) was used to per-form genotyping. Real-time PCR was performed in 25-µl . v.1.1 Cycle Sequencing Kit and the ABI 3500 sequencer (Applied Biosystems, Foster City, USA). Univariate analysis was performed to explain the char-acteristics of each studied variable. Normally distributed