2 2018 - American Transplant Congress (ATC)

Transcription

AMERICAN TRANSPLANT CONGRESSDay-at-a-Glance, Saturday, June 2, 20181:00 pm – 5:30 pmPre-Meeting SymposiaTransplant Center QAPIand Advanced Leadership:Navigating the ComplexRegulatory WatersRoom 6APage 6The Art and Science ofTransplantation (In collaborationwith NATCO and ITNS)Room 611-614Page 7Advanced ImmunologyRoom 606-607Page 8Basic Science for the ClinicianRoom 602-604Page 8The Immunology of KidneyTransplantationRoom 6BPage 9Managing and MitigatingTransplant InfectionsRoom 6CPage 10Reaching Across the Diaphragm:Dilemmas Posed by CombinedHeart and Liver Disease (CaseFocused Discussions)Room 615-617Page 11Immunobiology of ABMR –Bench to BedsideRoom 608-609Saturday, June 2Page 65:30 pm – 7:30 pmOpening Reception withExhibits and Exhibits andPoster Session APresenters in AttendanceHall 4EF5

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 2018Pre-Meeting Symposia1:00 pm – 5:30 pmAdvanced Transplant Leadership: CrisisManagementModerators: Linda Ohler, MSN CCTC, FAAN FAST,George Washington University Hospital, Vienna, VA,USA and Renee Bennett, BSN, Cleveland Clinic,Cleveland, OH, USATransplant Center QAPI and AdvancedLeadership: Navigating the ComplexRegulatory WatersRoom 6AClinical Aspects of a Transplant Quality ProgramModerators: Nahel Elias, MD, MassachusettsGeneral Hospital/Harvard Medical School, Boston,MA, USA and David Reich, MD, Drexel University,Philadelphia, PA, USA1:00 pm1:30 pm2:00 pm2:30 pmRegulatory Quality: What you Need toKnow: Clinical PerspectiveAmit Mathur, MD, MSMayo Clinic ArizonaPhoenix, AZ, USAProgram Approaching the SlipperySlopeJesse Schold, PhDCleveland ClinicCleveland, OH, USACrisis Management: Overall ConceptsMichael Abecassis, MDNorthwestern Memorial HospitalChicago, IL, USA4:05 pmCrisis Planning and Management: Howto Survive a Living Donor DeathChristiano Quintini, MDCleveland ClinicCleveland, OH, USA4:25 pmDisaster Planning: Natural orEnvironmentalMarion O’Rourke, RN, BSN, CCTCJackson Health SystemMiami, FL, USAAdvanced Transplant Leadership: RegulatoryReadinessModerators: Michelle James, MS, RN, CNS, CCTN,University of Minnesota, Minneapolis, MN, USA andAngie Korsun, RN, MSN, MPA, University of IowaHospitals & Clinics, Iowa City, IA, USAHow to See Your Way Clear AgainAtushi Yoshida, MDHenry Ford HospitalDetroit, MI, USA4:45 pmHow to Manage a Survey That Is NotGoing WellGwen McNatt, RN, PhD, CNN, FNP-BCNorthwestern Memorial HospitalChicago, IL, USA5:05 pmBalancing Strategy with FirefightingLuke PreczewskiJackson Health SystemMiami, FL, USA5:25 pmDiscussionThings that I Wish I had KnownAtushi Yoshida, MDHenry Ford HospitalDetroit, MI, USAAmit Mathur, MD, MSMayo Clinic ArizonaPhoenix, AZ, USAJesse Schold, PhDCleveland ClinicCleveland, OH, USAThe Art and Science of Transplantation(In collaboration with NATCO and ITNS)Room 611-614Marwan Abouljoud, MDHenry Ford HospitalDetroit, MI, USA3:15 pm3:45 pmCoffee Break6

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 2018Assessment and Care of a Complex PatientPopulation – Part IModerators: Penny Keaney, RN, BSN, MA, CCTC,The International Transplant Nurses Society,Rockville, MD, USA1:30 pmObesity and Transplantation: Tacklinga Weighty IssueDan Pieloch, MS, RD, CPHQRobert Wood Johnson University HospitalNew Brunswick, NJ, USALong Term Impact of High RiskDonors On Graft and RecipientOutcomesChristine Koval, MD, CCFCleveland Clinic FoundationCleveland, OH, USA5:45DiscussionAdvanced ImmunologyRoom 606-607Moderators: Xian Li, MD, PhD, Houston Methodist,Houston, TX, USA and Andrew Wells, PhD,University of Pennsylvania CHOP, Philadelphia, PA,USAYou Don’t Have to Like Them, But Approaches to Caring for Difficult orHostile PatientsCathy Crone, MDGeorge Washington University School ofMedicine / Inova Fairfax HospitalFalls Church, VA, USA1:00 pmAssessing Patients for Skin Cancer Pre and Post-TransplantLindsay Smith, MSNVanderbilt Transplant CenterNashville, TN, USAUpdate On Innate Sensors,Inflammasome Activation, andInflammationIgor Brodsky, AB, PhDUniversity of PennsylvaniaPhiladelphia, PA, USA1:30 pmPalliative Medicine and End of LifeCareTiffany Buda, MSNCleveland ClinicCleveland, OH, USAUpdate On Regulated Cell DeathMechanisms and ImplicationsAndreas Linkermann, MDTU DresdenDresden, Germany2:00 pmUpdate On Mechanisms of T CellDysfunctionLeonardo Riella, MD, PhDBrigham and Women s HospitalBoston, MA, USAAssessment and Care of a Complex PatientPopulation – Part IIModerators: Mary Francois, DNP, RN-BC, CCTC,UW Health/NATCO, Madison, WI, USA and DonnaDickt, BS, NATCO, Oak Hill, VA, USA2:30 pmUpdate On Non-Coding RNA inRegulation of Immune ResponsesSheri Krams, PhDStanford UniversityStanford, CA, USA3:45 pm3:00 pmCoffee Break3:30 pmUpdate On Metabolic Control ofImmune ResponsesUlf Beier, MDChildren’s Hospital of PennsylvaniaPhiladelphia, PA, USA4:00 pmUpdate On Epigenetic Regulation ofImmune ResponsesWayne Hancock, MD, PhDChildren’s Hospital of PhiladelphiaPhiladelphia, PA, USA2:00 pm2:30 pm3:00 pmDiscussion3:15 pmCoffee Break4:15 pm4:45 pmA2 to B or Not to BKeith Melancon, MDGeorge Washington UniversityWashington, DC, USAUnderstanding C1QBernice Coleman, PhD, RNCedars Sinai Medical CenterLos Angeles, CA, USALiver Tumor StagingJohnny Hong, MD, FACSMedical College of WisconsinMilwaukee, WI, USA7Saturday, June 21:00 pm5:15 pm

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 20184:30 pmUpdate On Microbiota in Regulation ofImmunity and ToleranceMaria-Luisa Alegre, MD, PhDUniversity of ChicagoChicago, IL, USA4:00 pmMemory Cells and Their Impact onAllograft ToleranceMandy Ford, PhDEmory UniversityAtlanta, GA, USA5:00 pmTop 10 Immunology Papers of the YearJonathan Bromberg, MD, PhDUniversity of Maryland School ofMedicineBaltimore, MD, USA4:25 pmTherapeutic Approaches to RejectionEnver Akalin, MDAlbert Einstein College of MedicineMontefiore Medical CenterBronx, NY, USA4:50 pmChronic Graft Rejection- Mechanismsand Emerging ApproachesRoslyn Mannon, MDUniversity of Alabama at BirminghamBirmingham, AL, USA5:15 pmDiscussionBasic Science for the ClinicianRoom 602-604Moderators: Jonathan Maltzman, MD, PhD, StanfordUniversity, Palo Alto, CA, USA and AlexanderKroemer, Georgetown University Hospital,Washington, DC, USA1:00 pm1:25 pm1:50 pm2:15 pm2:40 pm3:05 pm3:30 pmThe Immunology of Kidney TransplantationAn Overview of Immune ResponsesFrom Inception to MemoryPeter Heeger, MDIcahn School of Medicine at Mount SinaiNew York, NY, USARoom 6BModerators: Jennifer Trofe-Clark, Pharm D, BCPS,University of Pennsylvania, Philadelphia, PA, USAand Lisa Florence, MD, Swedish Medical Center,Seattle, WA, USAThe Innate Immune ResponseDangers, Sensors, and CellsFadi Lakkis, MDUniversity of PittsburghPittsburgh, PA, USAT Cells and Their Effector Mechanismsin RejectionRobert Fairchild, PhDCleveland ClinicCleveland, OH, USAThe Life Cycle of B Cells and TheirRoles in AlloimmunityGeetha Chalasani, MDUniversity of PittsburghPittsburgh, PA, USAEssential Mechanisms RegulatingImmune ResponsesQizhi Tang, PhDUniversity of California San FranciscoSan Francisco, CA, USAThe “Holy Grail” of TransplantationToleranceJonathan Maltzman, MD, PhDStanford UniversityPalo Alto, CA, USACoffee Break81:00 pmImmunobiology of Rejection for theNephrologistLeonardo Riella, MD, PhDBrigham and Women’s Hospital Boston,MA, USA1:20 pmImmunological Assessment of theTransplant RecipientKathryn Tinckam, MD, MMSc, FRCPCUniversity of Health NetworkToronto, ON, Canada1:40 pmImmunosuppression CurrentApproaches and Future StrategiesAndrew Adams, MD, PhDEmory UniversityAtlanta, GA, USA2:00 pmBeyond Conventional Pathology – NewApproaches to Diagnose Rejection –Potential Use and AdvantagesPaolo CravediIcahn School of Medicine at Mount SinaiNew York, NY, USA2:20 pmDiscussion

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 2018Issues in Recipient and Donor EvaluationModerators: Deirdre Sawinski, MD, University ofPennsylvania, Philadelphia, PA, USA and LauraMyhre, PharmD, BCPS, Mayo Clinic, Rochester, MN,USAEvaluation of the Combined OrganTransplant CandidateRichard Formica, MDYale UniversityNew Haven, CT, USA2:55 pmEvaluation of the Living Kidney DonorDavid Landsberg, MDSt. Paul’s Hospital, University of BritishColumbiaVancouver, BC, Canada3:10 pmPanel Discussion3:20 pm – 3:45 pm4:00 pm4:15 pm4:30 pmDiscussionRoom 6CCandidates, Donors & Recipients: Diving into TheDeep EndModerators: Daniel Kaul, MD, University of Michigan,Ann Arbor, MI, USA and Deepali Kumar, MD, MSc,FRCP, University Health Network , Toronto, ON,CanadaCoffee BreakSurgical Complications After KidneyTransplantation for the Non-surgeonKenneth Newell, MD, PhDEmory UniversityAtlanta, GA, USAManagement of Malignancy; Pre andPost-Transplant Considerations andManagementChris Blosser, MDUniversity of WashingtonSeattle, WA, USA1:00 pmID Evaluation of the Living DonorCameron Wolfe, MDDuke University Medical CenterDurham, NC, USA1:20 pmHIV Candidate: Pre-TransplantEvaluation and Post-TransplantManagementEmily Blumberg, MDPerelman School of Medicine at theUniversity of PennsylvaniaPhiladelphia, PA, USA1:40 pmImmunosuppression Considerationsfor The ID PhysicianJay Fishman, MDMassachusetts General HospitalBoston, MA, USA2:00 pmDiscussionBread and Butter Transplant IDModerators: Rachel Miller, MD, Durham, NC, USA &Stephanie Pouch, MD, MS, Emory University Schoolof Medicine, Atlanta, GA, USAManagement of the Failing/FailedAllograftJoshua Augustine, MDCleveland Clinic FoundationCleveland, OH, USA2:10 pmFungi Among Us: The AntifungalLandscapeBarbara Alexander, MDDukeDurham, NC, USA2:30 pmNon-Tuberculous Mycobacteria: FromOutbreaks to CandidatesFernanda Silveira, MD, MSUniversity of PittsburghPittsburgh, PA, USADiscussionTransplant InfectionsModerators: Joshua Augustine, MD, Cleveland ClinicFoundation, Cleveland, OH, USA and Chris Blosser,MD, University of Washington, Seattle, WA, USA4:45 pm5:15 pmManaging and Mitigating TransplantInfectionsAvoidance and Management of Early and LateComplicationsModerators: John Gill, MD, MS, University of BritishColumbia, Vancouver, BC, Canada and RichardFormica, MD, Yale University, New Haven, CT, USA3:45 pmBK Virus – Prevention and TreatmentDan Brennan, MDJohns Hopkins Medical InstituteBaltimore, MD, USAChallenging Cases in CMVAlissa Wright, MDUniversity of British ColumbiaVancouver, Canada9Saturday, June 22:40 pm5:00 pm

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 20182:50 pmParasites, SOT and Travel: A Long andWinding RoadCamille Kotton, MDMassachusetts General HospitalBoston, MA, USARapid-Fire Cases: Dare to DiagnoseModerators: Lara Danziger-Isakov, MD, MPH,Cincinnati Children’s Hospital Medical Center,Cincinnati, OH, USA and Camille Kotton, MD,Massachusetts General Hospital, Boston, MA, USA3:10 pmDiscussion5:00 pm3:20 pmCoffee BreakA Little Help from Our Friends: Collaborating forA DiagnosisModerators: Michelle Morris, MD, FACP, FIDSA,University of Miami, Miami, FL, USA and Ricardo LaHoz, MD, UT Southwestern Medical Center, Dallas,TX, USA3:45 pm4:05 pm4:25 pm4:45 pmCase PresentationsRicardo La Hoz, MDUT Southwestern Medical CenterDallas, TX, USANicole Theodoropoulos, MD, MS, FASTUMass Memorial Medical CenterWorcester, MA, USAJonathan Hand, MDOschner Medical CenterNew Orleans, LA, USADermatology and TransplantInfectious DiseaseFan Liu, MDUniversity of WashingtonSeattle, WA, USAJudith Anesi, MDUniversity of PennsylvaniaPhiladelphia, PA, USARadiology and Transplant InfectiousDiseaseJoel Fishman, MD, PhDUniversity of MiamiMiami Beach, FL, USAReaching Across the Diaphragm: DilemmasPosed by Combined Heart and Liver Disease(Case-Focused Discussions)Room 615-617Operation! A Surgeons View of TIDGeorge Mazariegos, MDChildren’s Hospital of PittsburghPittsburgh, PA, USACan I Do this Heart Transplant?Moderators: Shelley Hall MD, Baylor UniversityMedical Center, Dallas, TX, USA and Scott Biggins,MD, University of Washington, Seattle, WA, USADiscussionCASE 1: 27-Year-Old with a History of CongenitalHeart Disease s/p Fontan Procedure Who isUndergoing Evaluation for Heart Transplantation.101:00 pmReaching Adulthood Comes at a PriceGeorge Lui, MDStanford UniversityStanford, CA, USA1:20 pmHow Do I Assess Fibrosis in Patientswith Congenital Heart Disease?Patrick Kamath, MDMayo Clinic College of Medicine andScienceRochester, MN, USA1:40 pmPanel Discussion

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 2018CASE 2: 65-Year-Old Male with a History of DilatedCardiomyopathy, Diabetes and Obesity Admitted tothe CCU Who is Found to Have a Nodular Liver anda 1.5cm Mass on Imaging.The Nodular Liver in The Older Adultwith Heart Disease: Is It Cirrhosis?Catherine Frenette, MD, FAST, AGAFScripps Green HospitalLa Jolla, CA, USA2:20 pmFocal Liver Lesions in CongestiveHepatopathy: Is It HCC?Maarouf A. Hoteit, MDUniversity of PennsylvaniaPhiladelphia, PA, USA2:40 pmPanel Discussion3:00 pmCoffee BreakCan I Do this Liver Transplant?Moderators: Deepika Devuni, MD, University ofMassachusetts, Westborough, MA, USA and DanielGanger, MD, Northwestern University, Chicago, IL,USA4:05 pm4:25 pmEvaluation and Management ofIschemic Heart Disease Prior to LiverTransplantation: From Regulatoryto Reality: Critical Coronary ArteryStenosis Is 45 Year Old with A MELDof 40Sean Pinney, MDIcahn School of Medicine at Mount SinaiNew York, NY, USA5:00 pmValvular Heart Disease and LiverTransplant: Is TAVR an Option?Critical Valvular Heart Disease, How toApproachDuc Thinh Pham, MDNorthwestern UniversityChicago, IL, USA5:20 pmDiscussionImmunobiology of ABMR – Bench to BedsideCASE 1: 45-Year-Old Female with ESLD Secondaryto HCV Complicated by 3cm HCC and Prior Historyof Atrial Fibrillation Undergoing Evaluation for LiverTransplantation.3:45 pm4:40 pmRoom 608-609The Benchside View of ABMRModerators: Anat Tambur, DMD, PhD, NorthwesternUniversity, Chicago, IL, USA and Anita Chong, PhD,University of Chicago, Chicago, IL, USAHow Do I Assess CardiovascularPhysiology in End-Stage LiverDisease? Pearls and PitfallsRyan Tedford, MDMedical University of South CarolinaCharleston, SC, USACirrhotic Cardiomyopathy: Myth orReality?Lisa VanWagner, MD, MScNorthwestern UniversityChicago, IL, USA1:00 pmBiology of ABMRAnita Chong, PhDUniversity of ChicagoChicago, IL, USA1:20 pmDiscussion1:25 pmABMR – Effector PathwaysWilliam Baldwin, MD, PhDCleveland Clinic Main Campus, LernerResearch InstituteCleveland, OH, USA1:45 pmDiscussion1:50 pmHot Topics in ABMR PathologyDiagnosticsMichael Mengel, MDUniversity of AlbertaEdmonton, AB, Canada2:10 pmDiscussionPanel Discussion11Saturday, June 22:00 pmCASE 2: 64-Year-Old Male With ESLD Secondaryto Alcohol Complicated by Bleeding EsophagealVarices and Recurrent Hepatic Encephalopathy, PriorMI and HTN Found to have Severe Aortic Stenosison Screening Echocardiogram.

AMERICAN TRANSPLANT CONGRESSProgram, Saturday, June 2, 2018Hot Topics in ABMR SerumDiagnosticsNicole Valenzuela, PhD, D(ABHI)University of California, Los Angeles ImmunogeneticsLos Angeles, CA, USAPoster Session A – Presenters inAttendance2:35 pmDiscussion2:40 pmPanel Q&A – Case DiscussionPoster Session A can be found onpages 123-158.2:15 pm3:00 pm – 3:30 pmHall 4EFPoster Viewing: 5:30 pm – 7:30 pmPresenters in Attendance: 5:30 pm – 7:30 pmCoffee BreakThe Bedside View of ABMRModerators: Anat Tambur, DMD, PhD, NorthwesternUniversity, Chicago, IL, USA and Peter Nickerson,MD, Canadian Blood Services, Winnipeg, MB,Canada3:30 pmAccess for the Highly-SensitizedPatientMark Stegall, MDMayo ClinicRochester, MN, USA3:50 pmDiscussion3:55 pmIs There a Standard of Care for ABMR?Arjang Djamali, MDUniversity of Wisconsin School ofMedicine and Public HealthMadison, WI, USA4:15 pmDiscussion4:20 pmIs There a Link Between Acute/ChronicABMR?Mark Haas, MD, PhDCedars-Sinai Medical CenterLos Angeles, CA, USA4:40 pmDiscussion4:45 pmIs There Anything in The Pipeline forABMR?Peter Nickerson, MDCanadian Blood ServicesWinnipeg, MB, Canada5:05 pmDiscussion5:10 pmPanel Q&A – Case DiscussionOpening Reception with Exhibits5:30 pm – 7:30 pmHall 4EF12

AMERICAN TRANSPLANT CONGRESSDay-at-a-Glance, Sunday, June 3, 20187:00 am – 8:15 amPage 17Page 17Page 17Keep It Going! LongTerm Success After HeartTransplantationRoom 615-617Page 21Single vs. Dual KidneyTransplantation: 2 for 1 or 1 for2?Room 6BPage 21Page 21New Indications and Approachesin Targeting TregsRoom 6CRoom Hall 4BPage 2113ASTS Research AwardsRoom Hall 4B10:30 – 10:45 amDecision-Making for theComplicated Diabetic PatientRoom 608-609Page 20Room Hall 4B10:15 am – 10:30 amFrontiers in CMV - Bench toBedsideRoom 6ERole of Autophagy in Regulationof Immune ResponsesRoom 606-607AST Awards10:00 am – 10:15 am AST Lifetime AchievementAwardUnderstanding and OptimizingLiver Transplantation Outcomesin the Obese Cirrhotic PatientRoom 6APage 20Joint Award SessionRoom Hall 4B9:45 am – 10:00 amSunrise DidacticPage 19Page 19Page 21Plenary SessionPlenary Session IRoom Hall 4B9:30 am – 9:45 amMultidisciplinary TransplantTrainee Hot Topic DebateRoom 602-604VCA: Where are we now?Room 4C-3Page 19Page 20Virtual Transplant DiagnosticTestingRoom 611-614Page 18Special Considerations inTransplanting the Very YoungRoom 4C-48:30 am – 9:30 amPulmonary VascularComplications of Liver Disease:Management and Outcomes Preand Post-TransplantRoom 618-6207:00 am – 8:15 amPage 19Page 20ASTS Pioneer AwardRoom Hall 4B10:45 am – 11:15 amCoffee BreakExhibit Hall11:15 am – 12:45 pmMidday InteractivePage 21Liver Transplantation for AlcoholHepatitisRoom 6CPage 22Should We Continue PrioritizingKidney-Heart and Kidney-LiverTransplant Candidates OverKidney-Alone Candidates?Room 6BSunday, June 3Page 17Sunrise Interactive

AMERICAN TRANSPLANT CONGRESSDay-at-a-Glance, Sunday, June 3, 2018Page 22Is It Time to Change the PediatricKidney Allocation Paradigm fromExpedited Transplantation or toDelay Transplantation to FocusOn Better Class II HLA EpitopeMatching?Room 611-61411:15 am – 12:45 pmVCA: From Head to FingerUpdateRoom 4C-3Page 23To Pump or Not to PumpRoom 6APage 23Quagmires in Donor HeartAllocationRoom 618-620Page 23Acute and Chronic AntibodyMediated Rejection in LungTransplant: Alloimmunity andAutoimmunityRoom 615-617Page 24Top Papers in TransplantInfectious DiseasesRoom 6EPage 24Bench to Bedside- Costimulatoryand Co-Inhibitory Pathways inTransplantationRoom 602-604Page 24Page 25Sponsored SatelliteSymposia Located in theSheraton Seattle HotelSponsored by Sanofi GenzymePage 25Grand Ballroom A/B, Second FloorSponsored by One LambdaMidday DidacticPage 23Page 241:00 pm – 2:15 pmPage 25Metropolitan Ballroom A/B, ThirdFloor1:00 pm – 2:15 pmPage 25Luncheon WorkshopsTicketed EventsPage 25Controversies in BK: A CaseBased ApproachRoom 205Page 25Social Media in Organ Donationand EducationRoom 310Page 25Luncheon Workshop: Care ofAllograft Recipients in Transition(CARE - ART)Room 2041:30 pm – 4:00 pmTransplantation in Depth(Basic)Page 25Epigenetic Regulation of T CellResponsesRoom 608-609Mechanisms of Tissue Fibrosisand How They Apply to ChronicAllograft InjuryRoom 608-6092:30 pm – 6:00 pmEmerging Areas inRegulation of Immunity andImmunosuppressionRoom XXChallenges in ManagingAntibody-mediated AllograftInjuryRoom Hall 4B14Featured MultidisciplinaryTransplant ProfessionalsSymposium IPage 36Assessing and AddressingMedication Non-Adherence in the“Real World” Clinical SettingRoom 611-614Page 36The Science, The Art, And TheAllure of TransplantationRoom 618-620

AMERICAN TRANSPLANT CONGRESSDay-at-a-Glance, Sunday, June 3, 2018Page 37Assessing and AddressingMedication Non-Adherence in the“Real World” Clinical SettingRoom 611-6142:30 pm – 6:00 pmFeatured NursingSymposiumPage 37Innovation in Transplantation:Leadership and Education (InCollaboration with NATCO andITNS)Room 615-617Page 38Health LiteracyRoom 615-6172:30 pm – 4:00 pmConcurrent Oral AbstractSessionsAntigen Presentation /Allorecognition / Dendritic CellsRoom 4C-3Page 26Islet Cell and CellTransplantationRoom 2ABPage 27Kidney Acute Antibody MediatedRejectionRoom Hall 4BPage 28Page 294:30 pm – 6:00 pmConcurrent Oral AbstractSessionsPage 38Acute RejectionRoom 6APage 39Kidney Deceased DonorAllocation - 1Room 6EKidney Complications: DiseaseRecurrenceRoom Hall 4BPage 40Kidney Immunosuppression:mTORi Based RegimensRoom 6AKidney Donor Selection /Management Issues - 1Room 6EPage 40Kidney Immunosuppression: CoStimulation Based RegimensRoom 6CPage 41Kidney Psychosocial - 1Room 210Page 42Kidney Transplant Goes ViralRoom 606/607Page 43Kidney: Cardiovascular andMetabolic - 1Room 303Page 43Liver - Kidney Issues in LiverTransplantationRoom 6BPage 44Non-Organ Specific: Disparitiesto Outcome and Access toHealthcareRoom 4C-4Page 45Novel TherapeuticsRoom 602/603/604Page 30Kidney Infectious - Viral HepatitisRoom 4C-4Page 30Kidney Living Donor: SelectionRoom 606/607Page 31Kidney: Pediatrics - 1Room 3ABPage 32Liver: Immunosuppression andRejectionRoom 6BPage 33Liver: Recipient SelectionRoom 6CPage 34Lung: From Allocation toOutcomesRoom 303Page 34Small Bowel: All TopicsRoom 210Page 35XenotransplantationRoom 602/603/60415Sunday, June 3Page 26

AMERICAN TRANSPLANT CONGRESSDay-at-a-Glance, Sunday, June 3, 2018Page 45The Guest That NEVER Leaves:Immunologic Challenges in HeartTransplantationRoom 4C-35:45 pm – 7:00 pmASTS Town Hall andReceptionPage 46Room 2AB6:00 pm – 7:00 pmPoster Session BPresenters in AttendanceHall 4EF16

AMERICAN TRANSPLANT CONGRESSProgram, Sunday, June 3, 2018Sunrise Interactive7:00 am – 8:15 am7:40 amIntraoperative Management ofPortopulmonary Hypertension andHepatopulmonary HypertensionMichael Ramsay, MD, FRCABaylor University Medical CenterDallas, TX, USA8:00 amDiscussionKeep It Going! Long-Term Success AfterHeart TransplantationRoom 615-617Moderators: David Baran, MD, Sentara HeartHospital, Norfolk, VA, USA and Maryjane Farr, MD,Columbia University Medical Center, New York, NY,USA7:00 amRoom 611-614Moderators: Howard Gebel, PhD, Emory UniversityHospital, Atlanta, GA, USA and Annette Jackson,PhD, Johns Hopkins University, Baltimore, MD, USAHow Should We Monitor andImmunosuppress?Allen Anderson, MDNorthwestern UniversityChicago, IL, USAGetting Kids to Adulthood – ManagingThe Pediatric PopulationHannah Copeland, MDUniversity of MississippiJackson, MS, USA7:40 amA Third Chance – Which Patients andWhen for Retransplantation?Howard Eisen, MDDrexel University College of MedicinePhiladelphia, PA, USA8:00 amDiscussionPulmonary Vascular Complications of LiverDisease: Management and Outcomes Preand Post-TransplantRoom 618-620Moderators: Reena Salgia, MD, Henry Ford Hospital,Detroit, MI, USA and Srinath Chinnakotla, MD, MBA,University of Minnesota Medical School, Minneapolis,MN, USA7:00 am7:20 am7:00 amPredicting Lymphocyte CrossmatchOutcomes VirtuallyAnat Tambur, DMD, PhDNorthwestern UniversityChicago, IL, USA7:20 amUtilization of Virtual CrossmatchingAcross All Solid Organ Types withAccuracy: Limitations for Hitting theTargetRobert Bray, PhDEmory University HospitalAtlanta, GA, USA7:40 amVirtual Crossmatch: Patient Outcomesand Future DirectionsPeter Jindra, PhDBaylor College of MedicineHouston, TX, USA8:00 amDiscussionMultidisciplinary Transplant Trainee HotTopic DebateRoom 602-604Moderators: Christin Rogers, PharmD, BCPS, BethIsrael Deaconess Medical Center and Josh Levitsky,MD, MS, Northwestern University Feinberg School ofMedicine, Chicago, IL, USAScreening, Evaluation, And Treatmentof Porto-Pulmonary Hypertension(POPH)Michael Fallon. MDUniversity of Arizona College of MedicinePhoenix, AZ, USA7:00 amCurrent Approach to HepatopulmonarySyndrome (HPS) Diagnosis andManagementMichael Krowka, MDMayo ClinicRochester, MN, USA17Hopkins Team: Use of HCV DonorsShould Be Considered Standard ofCareSunday, June 37:20 amVirtual Transplant Diagnostic Testing

AMERICAN TRANSPLANT CONGRESSProgram, Sunday, June 3, 2018Team Mentor:Christine Durand, MDJohns Hopkins University School ofMedicineBaltimore, MD, USAUPENN Team:Behdad Besharatian, MDHospital of the University of PennsylvaniaPhiladelphia, PA, USAJudith Anesi, MDUniversity of PennsylvaniaPhiladelphia, PA, USAAndrew Cameron, MD, PhDJohns Hopkins UniversityBaltimore, MD, USAGrace Lee, MD, MSMEHospital of the University of PennsylvaniaPhiladelphia, PA, USAHopkins Team:Russell Wesson, MBChBJohns Hopkins UniversityBaltimore, MD, USAStephanie Hamel, PharmDHospital of the University of PennsylvaniaPhiladelphia, PA, USAJaime Glorioso, MDJohns Hopkins UniversityBaltimore, MD, USATherese Bitterman, MDUniversity of PennsylvaniaPhiladelphia, PA, USAWilliam Werbel, MDJohns Hopkins UniversityBaltimore, MD, USAMary Grace Bowring, MPHJohns Hopkins UniversityBaltimore, MD, USAChelsea Song, PharmD, BCPSJohns Hopkins UniversityBaltimore, MD, USA7:10 am7:20 amTeam Discussion7:25 amHopkins Rebuttal Supporting Standardof Care Position7:35 amUPENN Rebuttal SupportingRestriction to Research Position7:45 amQ&A from Judges and/or Audience8:00 amJudge/Audience DecisionJosh Levitsky, MD, MSNorthwestern University Feinberg Schoolof MedicineChicago, IL, USAUPENN Team: Use of HCV DonorsShould Be Restricted to ResearchProtocolsTeam Mentor:David Goldberg, MD, MSCEUniversity of PennsylvaniaPhiladelphia, PA, USASunrise Didactic7:00 am – 8:15 amVCA: Where are we now?Room 4C-3Moderators: Giuliano Testa, MD, FACS, MBA,Baylor University Medical Center, Dallas, TX, USAand Linda Cendales, MD, Duke University MedicalCenter, Durham, NC, USA7:00 am18Translational Science in VCA: Whereare we Now?Rolf Barth, MDUniversity of Maryland School ofMedicineBaltimore, MD, USA

AMERICAN TRANSPLANT CONGRESSProgram, Sunday, June 3, 20187:25 amCurrent Status of VCA in the UnitedStatesWida Cherikh, PhDUnited Network for Organ SharingRichmond, VA, USA7:50 amWhere Now From Here? EthicalConsiderations in VCAEmmanuel Morelon, MDUniversité de LyonLyon, France7:25 amBariatric Surgery and LiverTransplantation: Who, When andHow?Julie Heimbach, MDMayo ClinicRochester, MN, USA7:50 amPerioperative Morbidity and LongTerm Patient and Graft Survival inMorbidly Obese Liver TransplantRecipientsAndre Dick, MD, MPHSeattle Children’s HospitalSeattle, WA, USASingle vs. Dual Kidney Transplantation: 2 for1 or 1 for 2?7:00 amAdultRobert Stratta, MDWake Forest Baptist HealthWinston-Salem, NC, USA7:25 amPediatricRichard Perez, MDUniversity of California DavisSacramento, CA, USA7:50 amFrontiers in CMV - Bench to BedsideRoom 6EModerators: Andre Kalil, MD, University ofNebraska, Omaha, NE, USA and Nicolas Mueller,MD, University Hosp Zurich, Zurich, SwitzerlandUNOS Policy UpdatesMark Aeder, MDUniversity Hospitals Cleveland MedicalCenterCleveland, OH, USAUnderstanding and Optimizing LiverTransplantation Outcomes in the ObeseCirrhotic PatientCMV virology: What the ClinicianNeeds to KnowVincent Emery, BSc, PhDUniversity of SurreyGuildford, UK7:25 amCMV Immune Monitoring: Are we thereyet?Martina Sester, PhDSaarland UniversityHamburg, Germany7:50 amNew Antivirals for CMVAjit Limaye, MDUniversity of WashingtonSeattle, WA, USADecision-Making for the ComplicatedDiabetic PatientRoom 6AModerators: Erin Spengler, MD, University ofWisconsin School of Medicine and Public Health,Madison, WI, USA and Lisa VanWagner, MD,Northwestern University, Chicagol, IL USA7:00 am7:00 amRoom 608-609Moderators: Marlon Levy, MD, FACS, VCU,Richmond, VA, USA and Robert Redfield, MD,University of Wisconsin, Madison, WI, USAOptimizing Medical Management of theObese Liver Transplant CandidateKris Kowdley, MDSwedish Medical CenterSeattle, WA, USA197:00 amPancreas Transplant AloneDixon Kaufman, MD, PhDUniversity of WisconsinMadison, WI, USA7:25 amSPK v. Kidney AlonePeter Abrams, MDMedStar Georgetown Transplant InstituteWashington DC, USASunday, June 3Room 6BModerators: Jayme Locke, MD, MPH, FACS,University of Alabama at Birmingham, Birmingham,AL, USA and Richard Formica, MD, Yale University,New Haven, CT, USA

AMERICAN TRANSPLANT CONGRESSProgram, Sunday, June 3, 20187:50 amLiving Donor Kidney / Pancreas AfterKidneyMark Stegall, MDMayo ClinicRochester, MN, USA7:50 amSuppression, Anergy and ToleranceInter-RelationsDaniel Mueller, MDUniversity of MinnesotaMinneapolis, MN, USARole of Autophagy in Regulation of ImmuneResponsesSpecial Considerations in Transplanting theVery YoungRoom 606-607Moderators: Andrew Wells, PhD, University ofPennsylvania CHOP, Philadelphia, PA, USAand Jonathan Bromberg, MD, PhD, University ofMaryland School of Medicine, Baltimore, MD, USARoom 4C-4Moderators: Michael Green, MD, MPH, Children’sHospital of Pittsburgh, Pittsburgh, PA, USA andJorge Reyes, MD, University of Washington, Seattle,WA, USA7:00 amAutophagy and MemoryJin Wang, MDHouston MethodistHouston, TX, USA7:00 am7:25 amMechanisms and Implications ofRegulated Cell DeathAndreas LinkermanTU DresdenDresden, GermanyNeurocognitive Outcomes in VeryYoung Transplant RecipientsBeth Logan, PhDChildren’s Hospital of Pittsburgh ofUPMCPittsburgh, PA, USA7:25 amInfectious Complications in VeryYoung Transplant RecipientsLara Danzinger, MD, MPHCincinnati Children’s Hospital MedicalCenterCincinnati, OH, USA7:50 amImmunological Considerations for theYoung Transplant RecipientSrinath Chinnakotla, MD, MBAUniversity of Minnesota Medical SchoolMinneapolis, MN, USA7:50 amAutophagy in Regulation of OrganInjury and RepairJerzy Kupiec-Weglinski, MD, PHDUniversity of California, Los AngelesLos Angeles, CA, USANew Indications and Approaches inTargeting TregsRoom 6CModerators: Qizhi Tang, PhD, University ofCalifornia SF, San Francisco, CA, USA and AngusThompson, PhD, DSc, University of Pittsburgh,Pittsburgh, PA, USA7:00 am7:25 amBreak8:15 am - 8:30 amPlenary Session I8:30 am – 9:30 amChimeric Antigen Receptorsand Donor- Specific Tregs inTransplantationAntoine Sicard, MD, PhDUniversity of British ColumbiaVancouver, CanadaRoom Hall 4BChairs: Jean Emond and Ronald Gill8:30 amTregs Promote Chimerism andToleranceMegan Sykes, MDColumbia UniversityNew York, NY, USA20Carfilzomib and Belatacept ReducesDSA and Prolongs Survival in a HighlySensitized Rhesus Model of KidneyTransplantation (Abstract #1)Brian Ezekian, Jean Kwun, Paul M.Schroder, Miriam Manook, JanghoonYoon, Michael

Phoenix, AZ, USA 1:30 pm Program Approaching the Slippery Slope Jesse Schold, PhD Cleveland Clinic Cleveland, OH, USA 2:00 pm How to See Your Way Clear Again . Moderators: Penny Keaney, RN, BSN, MA, CCTC, The International Transplant Nurses Society, Rockville, MD, USA 1:00 pm Obesity and Transplantation: Tackling a Weighty Issue Dan Pieloch .