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2020:Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Apland, James P., Braga, Maria F. Targeting theglutamatergic system to counteract organophosphate poisoning: a novel therapeutic strategy. Neurobiology ofDisease, 133, 104406, 2020.Aroniadou-Anderjaska, Vassiliki, Apland, James P., Figueiredo, Taiza H., De Araujo Furtado, Marcio, Braga,Maria F. Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms ofaction, and medical countermeasures. Neuropharmacology, 181, 108298, 2020.Barker, Bryan S., Spampanato, Jay, McCarren, Hilary S., Smolik, Melissa, Jackson, Cecelia E., Hornung, EdenN., Yeung, David T., Dudek, F. Edward, McDonough, John H. Screening for efficacious anticonvulsants andneuroprotectants in delayed treatment models of organophosphate-induced status epilepticus. Neuroscience,425, 280-300, 2020.Betapudi, Venkaiah, Goswami, Reena, Silayeva, Liliya, Doctor, Deborah M., Chilukuri, Nageswararao. Genetherapy delivering a paraoxonase 1 variant offers long-term prophylactic protection against nerve agents in mice.Science Translational Medicine, 12(527), eaay0356, 2020.Bortey-Sam, Nesta, Jackson, Randy, Gyamfi, Obed A., Bhadra, Subrata, Freeman, Caleb, Mahon, Sari B.,Brenner, Matthew, Rockwood, Gary A., Logue, Brian A. Diagnosis of cyanide poisoning using an automated, fieldportable sensor for rapid analysis of blood cyanide concentrations. Analytica Chimica Acta, 1098, 125-132, 2020.Causey, Robert D., Koenig, Jeffery A., Autrey, Jeffery J., McGowan, Kevin J., Gomez, Amber M., Lehman, JohnG. III, Ruff, Albert L. Development of mouse models for the study of chloropicrin and hydrogen fluoride ocularinjury. Annals of the New York Academy of Sciences, 1479(1), 65-74, 2020.Cerasoli, Douglas M., Armstrong, Stuart J., Reeves, Tony E., Hodgins, Sean M., Kasten, Shane A., Lee-Stubbs,Robyn B., Cadieux, C. Linn, Otto, Tamara C., Capacio, Benedict R., Lenz, David E. Butyrylcholinesterase, astereospecific in vivo bioscavenger against nerve agent intoxication. Biochemical Pharmacology, 171, 113670,2020.Chen, Qingqing, Xu, Shiping, Lu, Xingyu, Boeri, Michael V., Pepelyayeva, Yuliya, Diaz, Elizabeth L., Soni, SunilDatta, Allair, Marc, Forstner, Martin B., Bahnson, Brian J., Rozovsky, Sharon. 77Se-NMR probes the proteinenvironment of selenomethionine. The Journal of Physical Chemistry B, 124, 601-616, 2020.Clarkson, Edward D., Gordon, Richard K. Decontamination and detoxification. In Handbook of Toxicology ofChemical Warfare Agents, 3rd ed., edited by R.C. Gupta. Cambridge, MA: Academic Press, 1233-1248, 2020.Connolly, Jessica M., Stevenson, Robert S., Railer, Roy F., Clark, Offie E., Whitten, Kimberly A., Lee-Stubbs,Robyn B., Anderson, Dana R. Impairment of wound healing by reactive skin decontamination lotion (RSDL ) in aGöttingen minipig model. Cutaneous and Ocular Toxicology, 39(2), 143-157, 2020.de Araujo Furtado, M., Aroniadou-Anderjaska, V., Figueiredo, T.H., Apland, James P., Braga, M.F.M.Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558with caramiphen. Annals of the New York Academy of Sciences, 1479(1), 122-133, 2020.DeLey Cox, Vanessa E., Hartog, Matthew A., Pueblo, Erin, Racine, Michelle, Jennings, Laura, Tressler, Justin,Tuet, Wing Y., Stone, Samuel, Pierce, Samuel A., Thompson, Lily, Dukes, Aliyah, Hoard-Fruchey, Heidi, Wong,Benjamin, McCranor, Bryan J. Methylene blue and monosodium glutamate improve neurologic signs afterfluoroacetate poisoning. Annals of the New York Academy of Sciences, 1479(1), 196-209, 2020.Dunn, Emily N., Matson, Liana M., Haines, Keri M., Whitten, Kimberly A., Lee-Stubbs, Robyn B., Berger, Kyle E.,McCarren, Hilary S., Ardinger, Cherish E., Jackson Piercy, Cecelia E., Miller-Smith, Stephanie M., McDonough,John H. Evaluation of fosphenytoin, levetiracetam, and propofol as treatments for nerve agent-induced seizures inpediatric and adult rats. Neurotoxicology, 79, 58-66, 2020.Koenig, Jeffrey A., Acon Chen, Cindy, Shih, Tsung-Ming. Development of a larval zebrafish model for acuteorganophosphorus nerve agent and pesticide exposure and therapeutic evaluation. Toxics, 8(4), 106, 2020.

Kundrick, Erica, Marrero-Rosada, Brenda, Stone, Michael, Schultz, Caroline, Walker, Katie, Lee-Stubbs, Robyn,de Araujo Furtado, Marcio, Lumley, Lucille A. Delayed midazolam dose effects against soman in male and femaleplasma carboxylesterase knockout mice. Annals of the New York Academy of Sciences, 1479(1), 94-107, 2020.Lam, Kwok-ho, Tremblay, Jacqueline M., Vazquez-Cintron, Edwin J., Perry, Kay, Ondeck, Celinia, Webb, RobertP., McNutt, Patrick M., Shoemaker, Charles B., Rongsheng, Jin. Structural insights into rational design of singledomain antibody-based antitoxins against botulinum neurotoxins. Cell Reports, 30(8), 2526-2539, 2020.Lang, X., Hong, X., Baker, Cetera A., Otto, Tamara C., Wheeldon, I. Molecular binding scaffolds increase localsubstrate concentration enhancing the enzymatic hydrolysis of VX nerve agent. Biotechnology andBioengineering, 117(7), 1970-1978 2020.Langston, Jeffrey L., Moffett, Mark C., Makar, Jennifer R., Burgan, Bradley M., Myers, Todd M. Carfentanil toxicityin the African green monkey: therapeutic efficacy of naloxone. Toxicology Letters, 325, 34-42, 2020.Lent, Emily M., Maistros, Kathleen J., Oyler, Jonathan M. In vitro dermal absorption of carfentanil. Toxicology InVitro, 62, 104696, 2020.Machamer, James B., Apland, James P., Winner, Brittany M., Wolfe, Sarah E., Pagarigan, Kathleen T.,Bounader, Kevin M., Kasten, Shane A., Adler, Michael, McNutt, Patrick M. Functional basis for dose-dependentantagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4. Archives ofToxicology, 94(11), 3877-3891, 2020.Marrero-Rosado, Brenda M., de Araujo Furtado, Marcio, Kundrick, Erica R., Walker, Katie A., Stone, Michael F.,Schultz, Caroline R., Nguyen, Donna A., Lumley, Lucille A. Ketamine as adjunct to midazolam reduces seizureseverity, epileptogenesis and brain pathology in soman-exposed carboxylesterase knockout mice. Epilepsy &Behavior, 111, 107229, 2020.McCarren, Hilary S. Eisen, Margaret R., Nguyen, Dominique L., Dubee, Parker B., Ardinger, Cherish E., Dunn,Emily N., Haines, Kari M., Santoro, Antonia N., Bodner, Paige M., Ondeck, Celinia A., Honnold, Cary L.,McDonough, John H., Beske, Phillip H., McNutt, Patrick M. Characterization and treatment of spontaneousrecurrent seizures following nerve agent-induced status epilepticus in mice. Epilepsy Research, 162:106320,2020.McCranor, Bryan J., Jennings, Laura, Tressler, Justin, Tuet, Wing Y., DeLey Cox, Vanessa E., Racine, Michelle,Stone, Samuel, Pierce, Samuel A., Pueblo, Erin, Dukes, Aliyah, Litvin, Samantha R., Leyden, Melissa R., Vignola,Justin N., Pennington, M. Ross, Wong, Benjamin. Assessment of naloxone as a therapeutic for inhaled carfentanilin the ferret. Toxicology Reports, 7, 1112-1120, 2020.McNutt, Patrick M., Nguyen, Dominique L., Nelson, Marian R., Lyman, Megan E., Eisen, Margaret M., Ondeck,Celinia A., Wolfe, Sarah E., Pagarigan, Kathleen T., Mangkhalakhili, Mark C., Kniffin, Denise M., Hamilton, TraceyA. Corneal endothelial cell toxicity determines long-term outcome after ocular exposure to sulfur mustard vapor.Cornea, 39(5), 640-648, 2020.McNutt, Patrick M., Hamilton, Tracey A., Lyman, Megan E., Nelson, Marian R. Ocular toxicity of chemical warfareagents. In Handbook of Toxicology of Chemical Warfare Agents, 3rd ed., edited by R.C. Gupta. Cambridge, MA:Academic Press, 567-588, 2020.McNutt, Patrick M., Mohan, Rajiv R. The need for improved therapeutic approaches to protect the cornea againstchemotoxic injuries. Translational Vision Science & Technology, 9(12), 2, 2020.Niquet, Jerome, Lumley, Lucille, Baldwin, Roger, Rossetti, Franco, Suchomelova, Lucie, Naylor, David, Estrada,Ireri Betsabe Franco, Schultz, Mark, de Araujo Furtado, Marcio, Wasterlain, Claude G. Rational polytherapy in thetreatment of cholinergic seizures. Neurobiology of Disease, 133, 104537, 2020.Oyler, Jonathan, Maistros, Kathleen, Oyler, Benjamin, Kilgour, David. Liquid Chromatography–MassSpectrometry in Analysis of Chemicals Related to the Chemical Weapons Convention. In Encyclopedia ofAnalytical Chemistry: Applications, Theory and Instrumentation. Chichester, United Kingdom: John Wiley & Sons,Ltd.Published Online 13 March 2020, https://doi.org/10.1002/9780470027318.a0408.pub3

Rice, Nathaniel C., Myers, Todd M. Organoleptic assessments as a tool for food defense chemical threatprioritization. In Agroterrorism: National Defense Assessment, Strategies, and Capabilities (ed. A. Mauroni and R.Norton). Maxwell Air Force Base, AL: United States Air Force Center for Strategic Deterrence Studies, 97-127,2020.Rice, Nathaniel C., Rauscher, Noah A., Moffett, Mark C., Myers, Todd M. Organoleptic assessment and medianlethal dose determination of oral aldicarb in rats. Annals of the New York Academy of Sciences, 1480(1), 136145, 2020.Tremblay, Jacqueline M., Vazquez-Cintron, Edwin, Lam, Kwok-Ho, Mukherjee, Jean, Bedenice, Daniela, Ondeck,Celinia A., Conroy, Matthieu T., Bodt, Skylar L., Winner, Brittany M., Webb, Robert P., Ichtchenko, Konstantin,Jin, Rongsheng, McNutt, Patrick M., Shoemaker, Charles B. Camelid VHH antibodies that neutralize botulinumneurotoxin serotype E intoxication or protease function. Toxins, 12(10), E611, 2020.Tuet, Wing Y., Racine, Michelle C., Jennings, Laura, Pierce, Samuel A., Tressler, Justin, McCranor, Brian J.,Wong, Benjamin. A sex-balanced rodent model for evaluating phosphine inhalation toxicity. Annals of the NewYork Academy of Sciences, 1479(1), 168-179, 2020.Vazquez-Cintron, Edwin, Machamer, James, Ondeck, Celinia, Pagarigan, Kathleen, Winner, Brittany, Bodner,Paige, Kelly, Kyle, Pennington, M. Ross, McNutt, Patrick. Symptomatic treatment of botulism with a clinicallyapproved small molecule. JCI Insight, 5(2), e132891, 2020.Warnakula, Indika K., Ebrahimpour, Afsin, Li, Sun Y., Gaspe Ralalage, Ramesha D., Hewa-Rahinduwage,Chathuranga C., Kiss, Marton, Rios, Christian T., Kelley, Kyler D., Whiteman, Ashley C., Thompson, David E.,Rockwood, Gary A., Petrikovics, Ilona. Evaluation of the long-term storage stability of the cyanide antidote:dimethyl trisulfide and degradation product identification. ACS Omega, 5(42), 27171-27179, 2020.Winner, Brittany M., Bodt, Skylar M.L., McNutt, Patrick M. Special Delivery: Potential mechanisms of botulinumneurotoxin uptake and trafficking within motor nerve terminals. International Journal of Molecular Sciences,21(22), 8715, 2020.Young, Sheena A., Capacio, Benedict R. Gas chromatography-tandem mass spectrometry verification of sulfurmustard exposure in humans through the conversion of protein adducts to free sulfur mustard. ChemicalResearch in Toxicology, 33(7), 1941-1949, 2020.

2019:Adler, Michael, Singh, Ajay K., Gul, Nizamettin, Lebeda, Frank. Medical countermeasures for intoxication bybotulinum neurotoxin. In Chemical Warfare Agents: Biomedical and Psychological Effects, MedicalCountermeasures, and Emergency Response, 3rd edition, edited by B.J. Lukey, J.A. Romano, Jr., and H. Salem.Boca Raton, FL: CRC Press, 227-244, 2019.Adler, Michael, Apland, James P., Deshpande, Sharad S., Koplovitz, Irwin, Lenz, David. Pyridostigmine protectionfrom nerve agent intoxication: concept to FDA Approval. In Chemical Warfare Agents: Biomedical andPsychological Effects, Medical Countermeasures, and Emergency Response, 3rd edition, edited by B.J. Lukey,J.A. Romano, Jr., and H. Salem. Boca Raton, FL: CRC Press, 373-392, 2019.Bellin, Michael A., Reitnauer, Kyle J., Gomez, Amber M., Lee-Stubbs, Robyn B., Ruff, Albert L. Evaluation of asynthetic bedding substrate for mice (Mus musculus). Journal of the American Association for Laboratory AnimalScience, 58(2), 154-159, 2019.Bhadra, Subrata, Zhang, Zhiling, Zhou, Wenhui, Ochieng, Fredrick, Rockwood, Gary A., Lippner, Dennean,Logue, Brian A. Analysis of potential cyanide antidote, dimethyl trisulfide, in whole blood by dynamic headspacegas chromatography-mass spectroscopy. Journal of Chromatography A, 1591, 71-78, 2019.Byrne, Timothy J., Vazquez, Raymond, Boehm, Dan, Rimpel, Laukton, Hurst, Charles G. Military chemicalcasualty treatment. In Chemical Warfare Agents: Biomedical and Psychological Effects, MedicalCountermeasures, and Emergency Response, 3rd edition, edited by B.J. Lukey, J.A. Romano, Jr., and H. Salem.Boca Raton, FL: CRC Press, 577-592, 2019.Capacio, Benedict R., Smith, J. Richard, diTargiani, Robert C., Pennington, M. Ross, Gordon, Richard K., Haigh,Julian R., Barr, John R., Lukey, Brian J., Noort, Daan. Clinical detection of exposure to chemical warfare agents.In Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and EmergencyResponse, 3rd edition, edited by B.J. Lukey, J.A. Romano, Jr., and H. Salem. Boca Raton, FL: CRC Press, 401442, 2019.Chilcott, Robert P., Lukey, Brian J., Slife, Harry F. Jr., Clarkson, Edward D., Hurst, Charles G., Braue, Ernest H.,Jr. Chemical warfare agent decontamination from skin. In Chemical Warfare Agents: Biomedical andPsychological Effects, Medical Countermeasures, and Emergency Response, 3rd edition, edited by B.J. Lukey,J.A. Romano, Jr., and H. Salem. Boca Raton, FL: CRC Press, 549-558, 2019.Dzisam, Joseph K., Brenner, Matthew, Mahon, Sari B., Rockwood, Gary A., Logue, Brian A. Determination of freecyano-cobinamide in swine and rabbit plasma by liquid chromatography tandem mass spectrometry. Journal ofChromatography B, Analytical Technologies in the Biomedical and Life Sciences, 1124, 100-108, 2019.Essler, Jennifer L., Smith, Paige G., Berger, Danielle, Gregorio, Elizabeth, Pennington, M. Ross, McGuire,Amanda, Furton, Kenneth G., Otto, Cynthia M. A randomized cross-over trial comparing the effect ofintramuscular versus intranasal naloxone reversal of intravenous fentanyl on odor detection in working dogs.Animals (Basel), 22, 9(6). pii: E385, 2019.Goldsmith, Moshe, Ashani, Yacov, Otto, Tamara C., Cadieux, C. Linn, Riddle, David S. Protein-basedbioscavengers of organophosphorus nerve agents. In Chemical Warfare Agents: Biomedical and PsychologicalEffects, Medical Countermeasures, and Emergency Response, 3rd edition, edited by B.J. Lukey, J.A. Romano,Jr., and H. Salem. Boca Raton, FL: CRC Press, 655-680, 2019.Goswami, Reena, Subramanian, Gayatri, Silayeva, Liliya, Newkirk, Isabelle, Doctor, Deborah, Chattopadhyay,Saurabh, Chilukuri, Nageswararao, Betapudi, Venkaiah. Gene therapy leaves a vicious cycle. Frontiers inOncology, 9, 297, 24 April 2019.Gupta, Vibhor, Cadieux, C. Linn, McMenamin, Deirdre, Medina-Jaszek, C. Angelica, Arif, Muhammad, Ahonkhai,Omua, Wielechowski, Erik, Taheri, Maryam, Che, Yan, Goode, Tamara, Limberis, Maria P., Li, Mingyao, Cerasoli,Douglas M., Tretiakova, Anna P., Wilson, James M. Adeno-associated virus-mediated expression of humanbutyrylcholinesterase to treat organophosphate poisoning. PLoS One, 14(11), e0225188, 2019.

Gyamfi, Obed A., Bortey-Sam, Nesta, Mahon, Sari B., Brenner, Matthew, Rockwood, Gary A., Logue, Brian A.Metabolism of cyanide by glutathione to produce the novel cyanide metabolite 2-Aminothiazoline-4oxoaminoethanoic acid. Chemical Research in Toxicology, 32(4), 718-726, 2019.Haines, Keri M., Matson, Liana M., Dunn, Emily N., Ardinger, Cherish E., Lee-Stubbs, Robyn, Bibi, David,McDonough, John H., Bialer, Meir. Comparative efficacy of valnoctamide and sec-butylpropylacetamide (SPD) interminating nerve agent-induced seizures in pediatric rats. Epilepsia, 60(2), 315-321, 2019.Hendry-Hofer, Tara B., Witeof, Alyssa E., Lippner, Dennean S., Ng, Patrick C., Mahon, Sari B., Brenner, Matthew,Rockwood, Gary A., Bebarta, Vikhyat S. Intramuscular dimethyl trisulfide: efficacy in a large swine model of acutesevere cyanide toxicity. Clinical Toxicology, 57(4), 265-270, 2019.Hoffman, Katie M., Eisen, Margaret R., Chandler, Jessica K., Nelson, Marian R., Johnson, Erik A., McNutt, PatrickM. Retrograde activation of CB1R by muscarinic receptors protects against central organophosphorus toxicity.Neuropharmacology, 155, 113-120, 2019.Hsu, Fu-Lian L., Bae, Su Y., McGuire, Jack, Anderson, Dana R., Bester, Stephanie M., Height, Jude J. Pegan,Scott D., Walz, Andrew J. Synthesis and molecular properties of nerve agent reactivator HLö-7dimethanesulfonate. ACS Medicinal Chemistry Letters, 10(5), 761–766, 2019.Jackson, Cecelia, Ardinger, Cherish, Winter, Kristin M., McDonough, John H., McCarren, Hilary S. Validating amodel of benzodiazepine refractory nerve agent-induced status epilepticus by evaluating the anticonvulsant andneuroprotective effects of scopolamine, memantine, and phenobarbital. Journal of Pharmacological andToxicological Methods, 97, 1-12, 2019.Johnstone, Timothy B.C., McCarren, Hilary S., Spampanato, Jay, Dudek, F. Edward, McDonough, John H.,Hogenkamp, Derk, Gee, Kelvin W. Enaminone modulators of extrasynaptic α4β3δ γ-aminobutyric acidA receptorsreverse electrographic status epilepticus in the rat after acute organophosphorus poisoning. Frontiers inPharmacology, 10, 560, eCollection 2019.Lee, Jangwoen, Rockwood, Gary, Logue, Brian, Manandhar, Erica, Petrikovics, Ilona, Han, Changhoon, Bebarta,Vikhyat, Mahon, Sari B., Burney, Tanya, Brenner, Matthew. Correction to Monitoring dose response of cyanideantidote dimethyl trisulfide in rabbits using diffuse optical spectroscopy. Journal of Medical Toxicology, 15(2), 139,2019.Lumley, Lucille A., Miller, Dennis, Muse, William T., Marrero-Rosada, Brenda, de Araujo Furtado, Marcio, Stone,Michael, McGuire, Jeffrey, Whalley, Christopher. Neurosteroid and benzodiazepine combination therapy reducesstatus epilepticus and long-term effects of whole-body sarin exposure in rats. Epilepsia Open, 4(3), 382-396,eCollection 2019.Lumley, Lucille A., Rossetti, Franco, de Araujo Furtado, Marcio, Marrero-Rosado, Brenda, Schultz, Caroline R.,Schultz, Mark K., Niquet, Jerome, Wasterlain, Claude G. Dataset of EEG power integral, spontaneous recurrentseizure and behavioral responses following combination drug therapy in soman-exposed rats. Data in Brief, 27,104629, 2019.Matson, Liana, Dunn, Emily, Haines, Kari, Miller-Smith, Stephanie, Lee-Stubbs, Robyn, Whitten, Kimberly,Ardinger, Cherish, McCarren, Hilary, McDonough, John. Evaluation of first-line anticonvulsants to treat nerveagent-induced seizures and prevent neuropathology in adult and pediatric rats. Neurotoxicology, 74, 203-208,2019.McCranor, Bryan J., Young, Talearia D., Tressler, Justin, Jennings, Laura, Irwin, James, Ali, Nazira A., Abilez,Marilynda K., Stone, Samuel, Racine, Michelle, Devorak, Jennifer L., Sciuto, Alfred M., Wong, Benjamin. Thecardiopulmonary effects of sodium fluoroacetate (1080) in Sprague-Dawley rats. Cogent Biology, 5, 1568669,2019.Moffett, Mark C., Rauscher, Noah A., Rice, Nathaniel C., Myers, Todd M. Survey of drug therapies against acuteoral tetramethylenedisulfotetramine poisoning in a rat voluntary consumption model. Neurotoxicology, 74, 264271, 2019.

Myers, Todd M. Human plasma-derived butyrylcholinesterase is behaviorally safe and effective in cynomolgusmacaques (Macaca fascicularis) challenged with soman. Chemico-Biological Interactions, 308, 170-178, 2019.Niquet, Jerome, Lumley, Lucille, Baldwin, Roger, Rossetti, Franco, Schultz, Mark, de Araujo Furtado, Marcio,Suchomelova, Lucie, Naylor, David, Franco-Estrada, Ireri, Wasterlain, Claude G. Early polytherapy forbenzodiazepine-refractory status epilepticus. Epilepsy & Behavior, 101(Pt B), 106367, 2019.Petrikovics, Ilona, Kiss, Lóránd, Chou, Ching-En, Ebrahimpour, Afshin, Kovács, Kristóf, Kiss, Márton, Logue,Brian, Chan, Adriano, Manage, Ananda B.W., Budai, Marianna, Boss, Gerry R., Rockwood, Gary A. Antidotalefficacies of the cyanide antidote candidate dimethyl trisulfide alone and in combination with cobinamidederivatives. Toxicology Mechanisms and Methods, 29(6), 438-444, 2019.Rice, Nathaniel C., Rauscher, Noah A., Wilkins, William L., Lippner, Dennean S., Rockwood, Gary A., Myers,Todd M. Behavioural and physiological assessments of dimethyl trisulfide treatment for acute oral sodium cyanidepoisoning. Basic & Clinical Pharmacology & Toxicology, 125(3), 289-303, 2019.Rockwood, Gary A. A bona fide need for a non-intravenous c

Rockwood, Gary A., Logue, Brian A. Analysis of the soil fumigant, dimethyl disulfide, in swine blood by dynamic . bridging therapy for a mass cyanide poisoning? Clinical Toxicology, 59(8), 734-739, 2021. . The Journal of Physical Chemistry B, 124, 601- 616, 2020.