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Francisco A. Arabía,MD CURRICULUMVITAE(as of 7/16/18)PERSONAL CONTACT INFORMATIONBanner University Medical Group2901 N. Central Ave., Suite 160Phoenix, AZ 9BS, Biomedical Engineering (magna cumlaude) Tulane University05/1983MDUniversity of Pennsylvania School of Medicine2004 – 2006MBAUniversity of Arizona07/1983 - 06/1984Internship, General SurgeryTulane University Affiliated Hospitals, New Orleans, LA07/1984 - 06/1985Residency, General SurgeryTulane University Affiliated Hospitals, New Orleans, LA07/1985 - 06/1987Clinical Associate, Surgical BranchNational Heart, Lung, and Blood Institute, National Institutes of Health07/1987 - 06/1989Residency, General SurgeryTulane University Affiliated Hospitals, New Orleans, LA07/1989 - 06/1990Chief Resident, General SurgeryTulane University Affiliated Hospitals, New Orleans, LA07/1990 - 06/1991Residency, Cardiothoracic SurgeryUniversity of Arizona, Tucson07/1991 - 06/1992Chief Resident, Cardiothoracic SurgeryUniversity of Arizona, TucsonPage 1 of 67
ADDITIONAL EDUCATION1996Surgical Management of End Stage Cardiac Failure (partial leftventriculectomy)Training and hands-on experienceBrazil2000LionHeartCompleted TrainingHershey, Pennsylvania2000Implantation of the Abiomed Total Artificial HeartSeminar and hands on trainingLouisville, Kentucky2001CO2 Transmyocardial Laser Revascularization (TMR)Completed TrainingRush-Presbyterian - St Luke's Medical CenterChicago, Illinois2002AbioCor Total ArtificialHeart Completed TrainingWilliam Harvey Conference Center, ABIOMED FacilityDanvers, Massachusetts2012 – PresentAmerican Heart Association (AHA)Advanced Cardiovascular Life Support (ACLS)LICENSURE06/198310/198507/199202/1994 – Present09/2012 – Present05/2013 – Present02/2014 – PresentLicensee, Medical Board of Louisiana, L017468Licensee, Medical Board of Maryland, D33006Licensee, Puerto Rico Commonwealth, 10685Licensee, Medical Board of Arizona, 22135Licensee, Medical Board of California, C55501Drug Enforcement AdministrationLicensee, California Department of Public Health(Fluoroscopy)BOARD CERTIFICATION1992 – PresentAmerican Board of SurgeryDiplomate1994 – PresentAmerican Board of Thoracic SurgeryThoracic SurgeryPage 2 of 67
PROFESSIONAL EXPERIENCE1992 – 1993Private Practice - San Pablo Cardiovascular, San Juan, Puerto Rico1994 – 1999Assistant Professor - Cardiothoracic Surgery, University of Arizona,Tucson, Arizona1996 – 2005Medical Director - MOBI Transport ProgramMobile intensive care1997 – 2005Consultant - UMC Phoenix Transplant Clinic, Phoenix, Arizona1997 – 2005Surgical Director - Lung Transplant Program, University of Arizona,Tucson, Arizona1997 – 2012Faculty (non-salaried) - Biomedical Engineering Department,University of Arizona, Tucson, AZCo-Director - Marshall Foundation Artificial Heart Program1998 – 20051999 – 2005Associate Professor - Cardiothoracic Surgery, University of Arizona,Tucson, Arizona2000 – 2005Surgical Director - Neonatal ECMO Program, University of Arizona,Tucson, Arizona2004 – 2005Physician Leader, Cardiovascular Program - University Medical Center,Tucson, Arizona2005 – 2012Surgical Director - Heart Transplant Program, Division of Cardiovascularand Thoracic Surgery, Department of Surgery, Mayo Clinic, Scottsdale,Arizona2005 – PresentProfessor of Surgery - Cardiothoracic Surgery, University of Arizona,Tucson, AZ2006 – 2012Professor of Surgery - College of Medicine, Mayo Clinic2006 – 2012Chair - Division of Cardiovascular and Thoracic Surgery, Department ofSurgery, Mayo Clinic, Phoenix, Arizona2012 – 2013Acting Professor of SurgeryCedars-Sinai Medical Center, Los Angeles CA2012 – 05/18Surgical Director – Mechanical Circulatory Support ProgramCedars-Sinai Medical Center, Los Angeles CA2012 – 05/18Director – CSHI Center for Surgical Device Management of AdvancedHeart DiseasePage 3 of 67
Cedars-Sinai Medical Center, Los Angeles CA2013 – 05/18Professor of SurgeryCedars-Sinai Professorial SeriesCedars-Sinai Medical Center, Los Angeles, CA2014 – 05/18Health Sciences Clinical ProfessorDavid Geffen School of MedicineUniversity of California Los Angeles2015 – 05/18Associate DirectorComprehensive Transplant CenterCedars-Sinai Medical Center, Los Angeles, CA2016 – 2017Co-Director – Division of Cardiothoracic SurgeryCedars-Sinai Medical Center, Los Angeles, CA2017 – 05/18Associate Director – Division of Cardiothoracic SurgeryCedars-Sinai Medical Center, Los Angeles, CA07/18 – PresentPhysician Executive – Advanced Heart ProgramBanner University Medical Group, Phoenix, AZEDUCATION AND TRAININGEducation on Total Artificial 19.20.21.Sharp Memorial Hospital, San Diego – 1996Cleveland Clinic Foundation - 2005University of Maryland – 2006Mayo Clinic Jacksonville – 2007Integris Medical Center – 2010Ohio State University - 2011USC Keck Hospital – 2011UPMC – University of Pittsburgh Medical Center – 2011University of Washington – 2011Texas Children’s Hospital – 2011Texas Heart Institute – 2011Montefiore Medical Center, NY – 2011Columbia University Medical Center – New York Presbyterian – 2011Cedars-Sinai Medical Center, Los Angeles – 2011Allegheny General Hospital – 2011Phoenix Children’s Hospital – 2012Ochsner Medical Center, New Orleans – 2012University of Minnesota – 2012UCLA Medical Center – 2012University of Kentucky - 2012Mayo Clinic Rochester – 2012Page 4 of 67
5.56.57.58.59.60.61.62.63.64.Children’s Hospital of Wisconsin – 2012Jewish Hospital and St Mary’s at University of Louisville – 2012Cincinnati Children’s Hospital – 2012Children’s Hospital of Philadelphia – 2012Baylor University Medical Center Dallas – 2012Inova Fairfax Hospital – 2013Boston’s Children Hospital – 2014Children’s Medical Center, Dallas – 2014Seattle’s Children Hospital – 2014University of Wisconsin – 2014Henry Ford Hospital, Detroit MI – 2015Carolinas Medical Center – 2015Duke University – 2015Banner University of Arizona – 2015Multi-Center – 2015PeaceHealth Bellingham – 2015University of Utah – 2015University of Alberta / Stollery Children’s – 2016University of Rochester / Strong Memorial Hospital – 2016Texas Heart Institute – 2016Texas Heart Institute – 2016Texas Children’s Hospital – 2016Hospital University of Pennsylvania (HUP) – 2016University of Kentucky Medical Center – 2016University of Alabama Medical Center – 2016University of Nebraska – 2017Baptist Medical Center Little Rock – 2017Baylor University Medical Center, Dallas – 2017Ohio State University – 2017Intermountain Medical Center – 2017University of Washington – 2017Jackson Memorial Medical Center – 2017University of Virginia – 2017Memorial Regional Hospital Hollywood, FL – 2017Allegheny Medical Center – 2017Baptist Memorial Hospital, Memphis TN – 2017University of Rochester – 2017Texas Heart Institute – 2017 (BiVACOR TAH x 2)Multi-Center – 2017Multi-Center – 2017Henry Ford Hospital, Detroit, MI – 2017Institute of Clinical and Experimental Medicine, Prague, Czech Republic– 2017 (CARMAT TAH)Integris Baptist Medical Center OKC - 2018Education on HeartWare Left Ventricular Assist Device1.Texas Heart Institute; Children’s Hospital of Colorado; Baylor Dallas TX;Page 5 of 67
VA Madison, WI; UT Houston, TX; University of Utah; VanderbiltUniversity – 20132.Intermountain Medical Center; University of Chicago; University ofMichigan; University of Alabama; Johns Hopkins University; OchsnerMedical Center; Sutter Memorial Medical Center; UC san Diego; OregonHealth and Science Center; Rady Children’s Hospital3.Stanford Medical Center, Mayo Clinic Phoenix, Sacred Heart, SpokaneWA – 20144.Seoul, Korea training at Cedars-Sinai – 20145.Kaiser Medical Center, Los Angeles, CA 20156.University of California, Irvine – 20157.PeaceHealth Bellingham, Bellingham, WA – 20178.National Taiwan University Medical Center, Taipei, Taiwan - 2017Education on Thoratec Centrimag1.Hoag Memorial Hospital, Long Beach Memorial Hospital, Orange CoastMemorial Hospital, Nevada Heart & Vascular Institute - 2013OUTREACH / INTER-FACILITY NEGOTIATION AND CONTRACTING1.Phoenix Children Hospital, Phoenix AZ and Cedars Sinai Medical Centeragreement to provide MCS Consulting Services. 2013 – Present2.PeaceHealth St. Joseph Medical Center, Bellingham WA and Cedars SinaiMedical Center agreement to provide MCS Consulting services. 2015 –PresentSt. Joseph’s Hospital and Medical Center Dignity Health Phoenix, AZ andCedars-Sinai Medical Center agreement to provide MCS ConsultingServices. 2015 – PresentCEDARS-SINAI INTRAMURAL ACTIVITIES3.1.2.3.4.5.6.7.Director, CSHI Center for Surgical Device Management of AdvancedHeart Disease. 2012 – PresentDirector, Mechanical Circulatory Support Program. 2012 – PresentCo-Director, ECMO Program. 2013 – PresentSurgical Director, Cardiothoracic Intensive Care Unit. 2014 – PresentChair, OR Task Force Committee. 2014 – PresentAssociate Director, Comprehensive Transplant Center. 2015 – PresentProject Leader, CSICU Quality Council. 2016 – PresentPage 6 of 67
8.9.10.ECMO Task Force. 2016 – PresentMobile Intensive Care Unit ECMO & Short-Term Devices. 2016 –PresentJoint Commission Preparatory Committee. 2017 – PresentPROFESSIONAL ACTIVITIES1979St. Jude Medical CorporationConsultant1978 – PresentTau Beta Pi, The Engineering Honor SocietyMember1978 – 1979Tulane Biomedical Engineering SocietyChair1988 – 1990Tulane University School of MedicinePhysical DiagnosisInstructor1993 – PresentAndrew Morrow Society of Cardiovascular SurgeonsMemberAmerican College of CardiologyFellow1994 – Present1994 – PresentAmerican College of SurgeonsFellow1994 – PresentAmerican Society for Artificial Internal OrgansMember1994 – PresentSociety of Thoracic SurgeonsMember1994 – PresentUnited Network for Organ Sharing (UNOS)Member1995 – PresentInternational Society For Heart and Lung TransplantationMember1997 – 2005Association for the Advancement of Medical InstrumentationMember1997 – 2005Southwest Oncology GroupMember1999 – PresentRegion 5 Thoracic Regional Review Board UNOSMemberPage 7 of 67
2002 – 2005Donor Network of Arizona Board of DirectorsMember2010 – PresentAmerican Association for Thoracic SurgeryMember2010 – PresentCouncil on Mechanical Circulatory Support, ISHLTMember2010 – PresentInteragency Registry for Mechanically Assisted Circulatory SupportData Access, Analysis & Publications CommitteeMember2015 – PresentInternational Editorial Review Board of Case Studies in Surgery (CSS)Member2016 – PresentWestern Thoracic Surgical AssociationMember2016 – PresentISHLT Registry for Mechanically Assisted Circulatory Support (IMACS)Executive BoardMember2017 – PresentMedtronic Independent Practitioner Quality Panel on MechanicalCirculatory SupportMemberUniversity Medical Center, Tucson1994 – 2005Intensive Care CommitteeMember1996 – 1998Medical Executive CommitteeMember-at-Large1996 – 2005Blood Utilization CommitteeMember1999 – 2005Operating Room CommitteeMemberUniversity of Arizona1998 – 2005Biomedical Engineering DepartmentInterdisciplinary Graduate ProgramMemberPage 8 of 67
University of Arizona1994 – 1996Finance CommitteeMember1995 – 1996Peer Review CommitteeMember1995 – 1996Self-Study Committee, Academic Review ProgramMember1996 – 2005Clinical Research Oversight CommitteeMember2002 – 2005Department of Surgery Administrative CabinetCommittee Member2004 – 2005College of Medicine Steering CommitteeMember2004 – 2005Liaison Committee, Department Chairman SearchCedars-Sinai1/2013 – PresentExecutive Transplant Committee 1/2013– PresentMCS Operation Committee2/2016 – PresentDepartment of Surgery Executive CommitteeCommunity Memberships & Services2010 – PresentArizona Astronomy BoardUniversity of Arizona Steward ObservatoryBoard Member2010 – 2012Phoenix Public Library FoundationBoard MemberJOURNAL RESPONSIBILITIES1998 – PresentJournal of Heart and Lung TransplantationJournal Referee1998 – PresentAnnals of Thoracic SurgeryPage 9 of 67
Journal Referee2012 – PresentASAIO JournalReviewer2013 – PresentJournal of Cardiovascular and Thoracic SurgeryReviewerEDUCATIONAL ACTIVITIES09/20/2003TeachingAbiomed Training Laboratory for Cardiothoracic SurgeonsArizona10/02/2003Surgical management of end stage heart diseaseMayo Clinic ArizonaScottsdale, Arizona04/2005Surgical management for end stage diseaseMayo Clinic HospitalScottsdale, ArizonaMentorship1996 – 1997Wilson, Don (Masters Student)Description: Master Dissertation on The Effects of Perfluorocarbon BloodSubstitute Emulsions on Leukocyte Function in Vivo.1997Gawley, Bryan (Pre-Med Student) 1997 –1998Cerney, Kristin (Masters Student)Description: Masters Dissertation for University of Arizona perfusionstudent on The Effects of Hyperoxia on Leukocyte Function within an inVitro Model of Extracorporeal Circulation1997 – 1998Jablonowski, Kurt (Masters Student)Description: Master Dissertation for University of Arizona perfusionstudent on Effects of Pentoxifyline in Heterotopic Rat Heart TransplantModel as a Function of its Potential as a Nitric Oxide Synthase Inhibitor1998Tsau, Pei H (Trainee)Description: Mentor at American Society for Artificial Internal Organs1998Moenning, Megan (Student)Description: University of Arizona Clinical Medicine preceptee2002 – 2003Dobson, Victoria (Masters Student)Description: Master Dissertation for University of Arizona perfusionPage 10 of 67
student on Effects of IL-10 on Extra Cellular Matrix Gene Expression byCardiac Fibroblasts2002 – 2003Pierce, Christopher (Masters Student)Description: Master Dissertation for University of Arizona perfusionstudent on The role of Proinflammatory Cytokines in Chronic AnemiaDisease with VAD Supported Patients2003Freeland, Shea (Student)Description: University of Arizona Longitudinal Clinical Curriculumpreceptee2006Agwai, Abigail (Graduate Student)Description: Master Dissertation on Preliminary HydrodynamicInvestigation of a Mechanical Bileaflet Heart Valve2013 – 2017Hou, Margaret (Med Student)2017 – PresentKleinheyer, Matthias (PhD Candidate)Description: Pulsatile Rotary TAHACADEMIC CAREER DEVELOPMENT09/08 – 09/10/2011International Society for Rotary Blood PumpsLouisville, Kentucky09/12 – 09/13/2011IntermacsBirmingham, Alabama09/29 - 10/01/2011Fourth International Heart Failure ForumBelgrade, Serbia12/01 - 12/04/20113rd Annual International Congress of CardiologyBeijing, People's Republic of ChinaHONORS/AWARDS01/1979Magna Cum Laude - Tulane University1979 – 1980Citizenship Award (for extraordinary contributions to the Department ofBiomedical Engineering) - Tulane University01/1994Who's Who Directory of Medical Specialists01/1996ASAIO/Lippincott-Raven Book Award for Abstract entitled, "SuccessRates of Long Term Circulatory Assist Devices Currently Used for BridgePage 11 of 67
to Heart Transplantation01/1996Yoshioka & Akutsu Price for abstract entitled, "Patient Selection forSuccessful Outcome with the CardioWest Total Artificial Heart as aBridge to Heart Transplantation"1998Training Award of Excellence - American Society for Artificial InternalOrgans01/2005 - 01/2006Best Doctors in AmericaGRANTS SUBMITTED1.Principal Investigator, Outcomes and Adverse Events for Total ArtificialHeart as Bridge to Transplantation. INTERMACS Database. In Progress.20152.Principal Investigator, Outcomes, adverse Events and Quality of Live forIntracorporeal, biventricular, centrifugal pumps. INTERMACS Database,pending review August 2015RESEARCH GRANTS AWARDEDPrincipal Investigator1.Principal Investigator, National Study, SynCardia 50 cc Total ArtificialHeart for Bridge to Transplantation. 2015 – Present2.Medical Monitor, National Study, SynCardia Total Artificial Heart forDestination Therapy2015 – Present3.Principal Investigator, HeartMate III LVAD Clinical Trial. 2015 - Present4.Principal Investigator, HeartWare LVAD Lateral Study. 2014 – Present5.Program Director / Principal InvestigatorThe HeartMate II Left Ventricular Assist System (LVAS) Pivotal StudyProtocol (Destination Therapy). Funded by Thoratec Corporation.04/2006 - 03/20126.Program Director / Principal Investigator08-003872/CentriMag VAS Failure-to-Wean from CardiopulmonaryBypass Trial. Funded by Thoratec Corporation11/2008 - 10/20097.Program Director / Principal Investigator08-005361/Evaluation of the VentrAssist Left Ventricular Assist Device asPage 12 of 67
a Bridge to Cardiac Transplantation – Pivotal Trial in: Evaluation of theVentrAssist Left Ventricular Assist Device as a Bridge to CardiacTransplantation – Pivotal Trial. Funded by Ventracor, Inc. (CLP06005)12/2008 - 11/20118.Program Director / Principal Investigator08-005401/VentrAssist - Destination Therapy in: Evaluation of theVentrAssist Left Ventricular Assist Device for the Treatment of AdvancedHeart Failure – Destination Therapy. Funded by Ventracor, Inc. (CLP12082)12/2008 - 11/20149.Program Director / Principal Investigator09-004814/ Evaluation of the Safety and Effectiveness of the DuraHeart LeftVentricular Assist System in: Evaluation of the Safety and Effectiveness of theDuraHeart Left Ventricular Assist System. Funded by TerumoCardiovascular Systems, Inc. (DH003)11/2009 - 11/201210.Program Director / Principal Investigator09-006472/ HW-003/ THE HEARTWARE LEFT VENTRICULARASSIST DEVICE (LVAD) SYSTEM in: 09-006472/ HW-003/Replacement Budget: THE HEARTWARE LEFT VENTRICULARASSIST DEVICE (LVAD) SYSTEM. Funded by HeartWare Inc. (N/A)01/2010 - 01/201711.Program Director / Principal Investigator09-007374/ CentriMag RVAS U.S. Post Approval Study (PAS) Protocol in:09-007374 Replacement Budget/ CentriMag RVAS U.S. Post ApprovalStudy (PAS) Protocol. Funded by Thoratec Corporation. (CentriMag RVAS)03/2010 - 03/201212.Program Director / Principal Investigator10-005239/ A Prospective, Randomized, Controlled, Un-blinded, MultiCenter Clinical Trial to Evaluate the HeartWare Ventricular Assist Systemfor Destination Therapy of Advanced Heart Failure. Funded by HeartWareInc. (HW-004)10/2010 - 10/201613.Principal InvestigatorThe Relationship between Serum Levels of Soluble Cell Adhesion Moleculesand the Development of Multiple Organ Failure in Patients implanted withCardiac Assist Devices. Funded by University Heart Center.01/1995 - 12/199514.Principal InvestigatorRelationship Between Cavitation in Mechanical Heart Valves, ArtificialHearts and High Frequency Ultrasonic Signals. Funded by American HeartAssociation Grant-In-Aid.01/1996 - 12/1996Page 13 of 67
15.Principal InvestigatorCMV disease in CMV mismatched heart transplant patients. The impact ofCytoGam on the incidence and severity of CMB disease in CMV high riskthoracic organ transplant recipients. Funded by CytoGam.01/1997 - 12/199716.Principal InvestigatorInteragency Registry of Mechanically Assisted Circulatory Support(INTERMACS DEVICE REGISTRY). (07-002278)04/2007 - 02/201317.Principal InvestigatorLevitronix CentriMag VAS: Failure-to-Wean from Cardiopulmonary BypassPivotal Trial. Levitronix. (08-003872)10/2008 - 09/201318.Principal InvestigatorEvaluation of the Heartware Left Ventricular Assist Device (LVAD)System. HeartWare, Inc. (09-006472)12/2009 - 09/201319.Principal InvestigatorCentriMag RVAS U.S. Post Approval Study (PAS) Protocol. LevitronixLLC. (09-007374)03/2010 - 02/201320.Principal InvestigatorA Prospective, Randomized, Controlled, Un-blinded, Multi-Center ClinicalTrial to Evaluate the HeartWare Ventricular Assist System for DestinationTherapy of Advanced Heart Failure. HeartWare, Inc. (10- 005239)09/2010 - 08/201321.Principal InvestigatorThe HeartMate II LVAS Pivotal Study Protocol. Thoratec Corporation.(06-003537)06/2006 - 07/201222.Principal InvestigatorINTERMACS (Interagency Registry for Mechanically Assisted CirculatorySupport). (06-005994)11/2006 - 10/200723.Principal InvestigatorEvaluation of the VentrAssist Left Ventricular Assist Device for theTreatment of Advanced Heart Failure - Destination Therapy - CLP12082.Ventracor Inc. (08-005401)11/2008 - 07/2009Page 14 of 67
24.Principal InvestigatorEvaluation of the VentrAssist Left Ventricular Assist Device as a Bridge toCardiac Transplantation - Pivotal Trial - CLP06005. Ventracor Inc. (08005361)11/2008 - 06/200925.Principal InvestigatorMCA Evaluation of the Safety and Effectiveness of the DuraHeart LeftVentricular Assist System in Patients Awaiting Transplantation. TerumoHeart, Inc. (09-004814)11/2009 - 01/201226.Principal InvestigatorInteragency Registry of Mechanically Assisted Circulatory Support(INTERMACS DEVICE REGISTRY). (CACS-0178)04/2014 – presentCo-Investigator1.Co-InvestigatorIn Vivo Matured Vascular Grafts for Coronary Artery Bypass Grafting.Funded by University Heart Center.01/1996 - 12/1997Industry2.Co-InvestigatorA cardiology/CT surgery study testing the effect of NA*/H* inhibitor onMI, high risk myocardial necrosis. Funded by Guardian Trial: Cariporide.01/1998 - 12/19983.Co-InvestigatorA phase 3 dose escalation study to evaluate safety and efficacy for theprevention and/or amelioration of acute renal failure in patients with renalimpairment who are undergoing elective cardiovascular surgicalprocedures in U.S. sites. Funded by Freedox Clinical Trial.01/1998 - 12/1998MAYO IRB DX-88 (Ecallantide) for the Reduction of Blood LossAssociated with Cardiopulmonary Bypass: A Phase 2 Randomized,Double-Blind, Placebo-Controlled, Multicenter Study in PatientsUndergoing Primary Coronary Artery Bypass Grafting, Single in: DX-88(Ecallantide) for the Reduction of Blood Loss Associated withCardiopulmonary Bypass: A Phase 2 Randomized, Double-Blind,Placebo-Controlled, Multicenter Study in Patients Undergoing PrimaryCoronary Artery Bypass Grafting, Single Valve Repair or Si. Funded byDyax Corporation.Page 15 of 67
01/2008 - 12/20095.Co-Investigator08-005619/Quark QRK.004/ INTRAVENOUS I5NP in: QRK.004/ APHASE I, RANDOMIZED, DOUBLE-BLIND, DOSE ESCALATIONTRIAL OF THE SAFETY AND PHARMACOKINETICS OF A SINGLEINTRAVENOUS INJECTION OF I5NP IN PATIENTS AT HIGH RISKOF ACUTE KIDNEY INJURY UNDERGOING MAJORCARDIOVASCULAR SURGERY. Funded by Quark Pharmaceuticals.(QRK.004)02/2009 - 01/2011Mayo Clinic6.Co-Investigator07-005029/Boston Scientific, Development, Gift / 3-D CT for accessingairways and planning stent placement: Results, performance & follow-upin: The use of CT Bronchoscopy for planning stent placement. Funded byDevelopment - Gifts from benefactors. (R07005)09/2009 - 09/2012Completed GrantsFederal7.Co-InvestigatorMitochondrial dysfunction and susceptibility to Atrial Fibrillation in theElderly. Funded by National Heart, Lung, and Blood Institute. (R01 R01HL101240)04/2010 - 08/2011Foundation8.Co-Principal InvestigatorInfection Database of Mechanical Circulatory Assist Device Recipients.no funds. (09-001079)03/2009 - 02/20139.Co-Principal InvestigatorEcho-Doppler characteristics of the SynCardia Total Artificial Heart. NoMayo funding required. (10-006326)09/2010 - 08/201310.Co-InvestigatorThrombogram Testing in Cardiac Surgery Patients. (08-002594)06/2008 - 04/201311.Co-InvestigatorCharacterization of microRNA Biomarkers in Cardiac Disease. (08002826)09/2008 - 08/201312.Co-InvestigatorPage 16 of 67
Identifying microRNA biomarkers useful for early detection of recurrencein esophageal cancer patients. we are doing this ourselves. (09-000428)05/2009 - 04/201313.Co-InvestigatorEvaluation of Gastrointestinal Complications Following Cardiac Surgery.no funding required. (10-000745)04/2010 - 04/201314.Co-InvestigatorArrhythmia Burden and Outcomes in Patients Receiving Left VentricularAssist Device. No specific funds. (10-004046)06/2010 - 06/2013Completed15.Co-Principal InvestigatorReview of artificial support devices. (08-003388)06/2008 - 05/201016.Co-InvestigatorComparison of Intraoperative Cardiac Imaging Techniques – Real Time3D Transesophageal Echocardiography and Real Time Epicardial 3DEchocardiography. (08-008466)01/1900 - 10/201017.Co-Investigator"Prospective Randomized Trial of Low Dose Oral Amiodarone Use inPreventing Atrial Fibrillation Following Pulmonary Resections". (948-02)09/2002 - 06/200718.Co-Investigator"An Open Label Extension Trial to Determine Safety and Efficacy ofLong-Term Oral SPM 927 in Patients with Partial Seizures". (1435-05)07/2005 - 12/200919.Co-InvestigatorCardio-Pulmonary Impairment and Post-Operative Results FollowingPectus Repair. (06-006597)02/2007 - 09/200920.Co-InvestigatorKALAHARI 1: Kallikrein Antagonist (DX-88[Ecallantide]) Effect on Blood Loss Associated with Heart SurgeryRequiring Institution ofBypass. Dyax Corp. (06-008774)02/2007 - 02/200921.Co-InvestigatorEvaluation of the Incremental Value of the Real-Time 3D IntraoperativePage 17 of 67
Transesophageal Echocardiography in Cardiac Surgery: Comparison withthe conventional 2D multiplane transesophageal echocardiography. (07006533)10/2007 - 09/200822.Co-InvestigatorThe use of CT Bronchoscopy for planning stent placement. BostonScientific. (07-005029)10/2007 - 08/201223.Co-InvestigatorRetrospective chart review of patients who had left ventricular assistdevices implanted at Mayo Clinic Arizona, Rochester and Jacksonville.(08-003808)07/2008 - 05/201224.Co-InvestigatorA Phase I, Randomized, Double-Blind, Dose Escalation Trial of the SafetyAnd Pharmacokinetics of a Single Intravenous Injection of I5NP inPatients at High Risk of Acute Kidney Injury Undergoing MajorCardiovascular Surgery - QRK.004. Quark Pharmaceuticals, Inc. (08005619)01/2009 - 10/201025.Co-InvestigatorMitochondrial Dysfunction and Susceptibility to Atrial Fibrillation in theElderly. NHLBI/ NIH. (09-007827)12/2009 - 12/201126.Co-InvestigatorThe effect of active and passive range of motion on oxygen consumptionin patients after coronary artery bypass graft (CABG) surgery. No fundingrequired, routine collection of data during the course of a physical therapytreatment. (09-007579)04/2010 - 04/201227.Co-InvestigatorImpact of SynCardia Total Artificial Heart on Renal Function in PatientsBridged to Heart Transplant. No Mayo funds. (11-000073)09/2011 - 09/2012RESEARCH INTERESTS National Institutes of Health Clinical Associate, National Heart, Lung andBlood Institute, Surgery Branch, Bethesda, Maryland. Unanimously votedto participate in a two-year assignment with state-of-the-art techniques andequipment pertaining to heart surgery and artificial heart valves.Performed numerous studies in hemodynamics.Page 18 of 67
Aerospace and Mechanical Engineering, University of ArizonaCollaborating with Professor Erdogan Madenci on the study of mechanicalcirculatory devices.1996 - Left Partial Ventriculectomy. Patients with dilated cardiomyopathy(viral and idiopathic) that have been accepted for heart transplantation.Principle investigator. 100% effort. (Internal project. Reimbursementwaived)CardioWest-TAH. Implantation of NYHA Class IV patients. Co-PrincipalInvestigator. 50% effort. CardioWest Technologies, Inc. is a non-profitorganization with no available research capital. Unfunded trial. IRB #07-002278. Intermacs. (Interagency Registry of MechanicallyAssisted Circulatory Support) Opened in 2007. Approved. IRB #09-004814. Terumo Duraheart. Approved. IRB #09-006472. HeartWare. Approved.PRESENTATIONS06/87Doppler derived pressure difference. Invitro studies of artificial heart valves.National Heart, Lung & Blood Institute, NIH. Bethesda, MD.10/88Congenital heart disease: An overview. General Surgery Residents Conference,Department of Surgery, Tulane University. New Orleans, LA.10/88Surgical management of burn patients. General Surgery Residents Conference,Department of Surgery, Tulane University. New Orleans, LA.12/88Acquired heart disease: An overview. General Surgery Residents Conference,Department of Surgery, Tulane University. New Orleans, LA.04/89Venous disease of the lower extremities. Surgical Grand Rounds, Department ofSurgery, Tulane University. New Orleans, LA.09/89Surgical infections. General Surgery Residents Conference, Department ofSurgery, Tulane University. New Orleans, LA.10/89Diseases of the small intestine. General Surgery Residents Conference,Department of Surgery, Tulane University. New Orleans, LA.01/90Peutz-Jeghers Syndrome. Patient presentation and discussion. Surgical GrandRounds, Department of Surgery, Tulane University. New Orleans, LA.08/90Thymoma & Myasthenia Gravis. Cardiothoracic Surgery Conference, Section ofCardiovascular & Thoracic Surgery, University of Arizona. Tucson, AZ.Page 19 of 67
10/90Thoracic Trauma I. Cardiothoracic Surgery Conference, Section ofCardiovascular & Thoracic Surgery, University of Arizona. Tucson, AZ.11/90Thoracic Trauma II. Cardiothoracic Surgery Conference, Section ofCardiovascular & Thoracic Surgery, University of Arizona. Tucson, AZ.12/90Thoracic Trauma III. Cardiothoracic Surgery Conference, Section ofCardiovascular & Thoracic Surgery, University of Arizona. Tucson, AZ.02/91Preoperative assessment for lung resection. Cardiothoracic Surgery Conference,Section of Cardiovascular & Thoracic Surgery, University of Arizona. Tucson,AZ.05/91Cardiac and pericardiac tumors. Cardiothoracic Surgery Conference, Section ofCardiovascular & Thoracic Surgery, University of Arizona. Tucson, AZ.06/91Mesothelioma: Diagnosis and management. Cardiothoracic Surgery Conference,Section of Cardiovascular & Thoracic Surgery, University of Arizona. Tucson,AZ.06/91Design & testing of mechanical heart valves. Cardiothoracic Surgery Conference,Section of Cardiovascular & Thoracic Surgery, University of Arizona. Tucson,AZ03/92Pulmonary tuberculosis and the Thoracic Surgeon. Cardiothoracic SurgeryConference, Section of Cardiovascular & Thoracic Surgery, University ofArizona. Tucson, AZ.05/92Surgical management of Bullous Emphysema. Cardiothoracic SurgeryConference, Section of Cardiovascular & Thoracic Surgery, University ofArizona. Tucson, AZ06/92Palliative procedures for congenital heart disease. Cardiothoracic SurgeryConference, Section of Cardiovascular & Thoracic Surgery, University ofArizona. Tu
23. Jewish Hospital and St Mary's at University of Louisville - 2012 24. Cincinnati Children's Hospital - 2012 25. Children's Hospital of Philadelphia - 2012 26. Baylor University Medical Center Dallas - 2012 27. Inova Fairfax Hospital - 2013 28. Boston's Children Hospital - 2014 29. Children's Medical Center, Dallas .
